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The map label for this gene is csgD [H]

Identifier: 146283191

GI number: 146283191

Start: 3073878

End: 3074525

Strand: Direct

Name: csgD [H]

Synonym: PST_2856

Alternate gene names: 146283191

Gene position: 3073878-3074525 (Clockwise)

Preceding gene: 146283187

Following gene: 146283192

Centisome position: 67.3

GC content: 66.05

Gene sequence:

>648_bases
ATGAAAGACGACGTCGTGCCGGCCTATCAGCCCAACTCCCCCCGTGTACTGCTGCTTTCGGCCAGCAGCTCGCTCAACAG
CACCCTGCGGCAGCATCTGTACGATTGCCCCGACTGGACGCTCAGCCACGCCTCGGCACCGCGCGGCGAGGTCGAGGCAG
CGCTGGTGCTGCTCGACGTGGGGAGCTACGACCGCGACACCAACGTTCACCTGCTCAGGCAGATCGGCGACACGCCGGTC
GCGCTGGTCAATGCGCAGCCGGACCAGGCGCGCCGGCTGGTCGAAACCCACCCATGGATCCGTGGCGTGTTCTACCGCGC
CACCCCGCGCACCATCTTCGTTCGCGGCATCCGCACGCTGCTCACCGGCGGCGACTGGCTGCCACGGGAGCTGATGGAGG
CACTGCTGTCACGCTACCGGCAGCTGAGCAGCGCCAATCAAGTGATCGATGAGCTGACGCTGCGGGAGAAGCAGATTCTC
GCCCTCGCCGGTCAGGGTCTTTCCAATGCGGAGATCGGCGAGAAGCTGCACCTGAGCATCCATACCATCAAGAGCCATGT
GCACAACGCTCTGCGCAAACTGGGCGCGAGCAACCGTGCCCAGGGCGCCTCGCTGGTACTCGCCCACGTCAGCGAGGCGG
TGTCGTGA

Upstream 100 bases:

>100_bases
ACTTTTTTTTGTCGCAAAGCTGAACTACTTTCAGTTGCGCGTGGATGCTTAAGCCCACGCGTCCAGGACTCCCCTTCAAC
ATTCAGCAAAGGACATGCGA

Downstream 100 bases:

>100_bases
AACGCACCGGCGCGCTGCTTCTGCTGCTGGTGGGCCTGACGGCCCAGGCAGACGAAGCCGAGCTGCAGGGTTTCATCACC
AACAACACGATTTCCCGCTC

Product: LuxR family DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKDDVVPAYQPNSPRVLLLSASSSLNSTLRQHLYDCPDWTLSHASAPRGEVEAALVLLDVGSYDRDTNVHLLRQIGDTPV
ALVNAQPDQARRLVETHPWIRGVFYRATPRTIFVRGIRTLLTGGDWLPRELMEALLSRYRQLSSANQVIDELTLREKQIL
ALAGQGLSNAEIGEKLHLSIHTIKSHVHNALRKLGASNRAQGASLVLAHVSEAVS

Sequences:

>Translated_215_residues
MKDDVVPAYQPNSPRVLLLSASSSLNSTLRQHLYDCPDWTLSHASAPRGEVEAALVLLDVGSYDRDTNVHLLRQIGDTPV
ALVNAQPDQARRLVETHPWIRGVFYRATPRTIFVRGIRTLLTGGDWLPRELMEALLSRYRQLSSANQVIDELTLREKQIL
ALAGQGLSNAEIGEKLHLSIHTIKSHVHNALRKLGASNRAQGASLVLAHVSEAVS
>Mature_215_residues
MKDDVVPAYQPNSPRVLLLSASSSLNSTLRQHLYDCPDWTLSHASAPRGEVEAALVLLDVGSYDRDTNVHLLRQIGDTPV
ALVNAQPDQARRLVETHPWIRGVFYRATPRTIFVRGIRTLLTGGDWLPRELMEALLSRYRQLSSANQVIDELTLREKQIL
ALAGQGLSNAEIGEKLHLSIHTIKSHVHNALRKLGASNRAQGASLVLAHVSEAVS

Specific function: The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA t

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787277, Length=201, Percent_Identity=31.3432835820896, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 23730; Mature: 23730

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDDVVPAYQPNSPRVLLLSASSSLNSTLRQHLYDCPDWTLSHASAPRGEVEAALVLLDV
CCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEC
GSYDRDTNVHLLRQIGDTPVALVNAQPDQARRLVETHPWIRGVFYRATPRTIFVRGIRTL
CCCCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHCHHHHHEEEECCCHHHHHHHHHHH
LTGGDWLPRELMEALLSRYRQLSSANQVIDELTLREKQILALAGQGLSNAEIGEKLHLSI
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
HTIKSHVHNALRKLGASNRAQGASLVLAHVSEAVS
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKDDVVPAYQPNSPRVLLLSASSSLNSTLRQHLYDCPDWTLSHASAPRGEVEAALVLLDV
CCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEC
GSYDRDTNVHLLRQIGDTPVALVNAQPDQARRLVETHPWIRGVFYRATPRTIFVRGIRTL
CCCCCCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHCHHHHHEEEECCCHHHHHHHHHHH
LTGGDWLPRELMEALLSRYRQLSSANQVIDELTLREKQILALAGQGLSNAEIGEKLHLSI
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
HTIKSHVHNALRKLGASNRAQGASLVLAHVSEAVS
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8817489; 8905232; 9278503 [H]