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The map label for this gene is csdA [H]

Identifier: 146283175

GI number: 146283175

Start: 3058781

End: 3059986

Strand: Direct

Name: csdA [H]

Synonym: PST_2840

Alternate gene names: 146283175

Gene position: 3058781-3059986 (Clockwise)

Preceding gene: 146283174

Following gene: 146283176

Centisome position: 66.97

GC content: 67.08

Gene sequence:

>1206_bases
ATGGCCCTGTTCTCCCCCTGGCGCGCTGACTTCCCCGCTCTGGCCGTGCTCGAAGCACAAGGCCAGACCTACCTCGACAG
CGCCGCCACGGCACAGAAGCCGCAGGCGCTGATCGATGCCCTCAGCGGTTACTACACCTGCGGTGCGGCCAACGTGCACC
GTGCCCAGCACCAACCTGCCGAACGCGCCACCCGTGCCTACGAAGACGCCCGTATCAAAGTCGCCAAGTGGCTGAATGCC
GCCTGCCCGACCGAAATCGTGTTCACCCGTGGCGCGACCGAAGCGCTGAACCTGCTCGCCTACGGCCTGGAACACCTGAT
CGAAGCCGGCGACGAGATCGTCATCAGCGCCCTCGAGCATCACGCCAATCTGCTGCCCTGGCAGCAGCTGGCCAAACGTC
GAGCGGCCAAGCTGCAGGTACTGCCCATCGATGCCTCCGGGCGTATCGACCTCGCCGCGGCCGCCGGGCTGATCGGGCCG
CGCACGCGGCTGCTGGCGGTGAGTCAGTTGTCCAACGTGCTCGGCTGCTGGCAGCCGCTCGAACCGTTGCTGCGCCTGGC
CAAGGCACAGGGCGCGCTGACTGTCGTCGATGGTGCGCAAGGTGTGGTCCACGGGCGCCATGACATGACCACGCTGGGCT
GCGACTTCTATGTGCTGTCCAGCCACAAGCTCTACGGGCCGGATGGCGTCGGCGCGCTCTATGGGCGCGGCGAATCCCTG
CTGCAGCTGCGTCACTGGCAGTTCGGCGGCGAGATGGTGCGGATCGCCGACTACCAGAGTGCCGAGTTTCATGCCGCGCC
ACTGGGTTTCGAGGCCGGCACACCGCCGATTTCCGGCGTGATCGGGTTGGGCGCCGCACTGGACTATCTCGCCGCCCTCG
ATGCCACCGCGGTCGGCCGTCATGAACAGGCGTTGCACGACCTGTTGCTCGCCGGCCTCGCCGAGCGCAGCGGCATTCGT
CTGCTCGGCGCGCCGCAGGTCGCTCTGGCCAGCTTTGTTGTCGACGGTGTGCACCATTCCGATCTCGGTCACCTGCTCAC
CGAGCAGGGCATCGCCGTGCGCAGCGGCAACCACTGCGCCATGCCGCTCATGAAGCATCTCGGCCTGGATGGCGCCACGC
GCGTCTCGCTCGGCCTGTACAACGACCACAACGATCTGCAGCGCTTCTTCGATGCGCTGGACCAGGCCCTGGAGCTGCTG
CGATGA

Upstream 100 bases:

>100_bases
TGAACGAGGCGCTGCACGCGCATAACTGACGGGAGCAGCGGCAAGCTGCGAGCCATGAGCGCCTGCCTTGCCGCACCCTG
TTGCACGAGGCTTGCCGCTT

Downstream 100 bases:

>100_bases
GTGAACTGCCCGACGCCGCCCGAGAGGCCTTGGCGACCTTCGCCCAGGCGCCTGGCTGGGAGCAGCGCGCACGCCTGCTG
ATGCAGTGGGGGGAACGGCT

Product: cysteine sulfinate desulfinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MALFSPWRADFPALAVLEAQGQTYLDSAATAQKPQALIDALSGYYTCGAANVHRAQHQPAERATRAYEDARIKVAKWLNA
ACPTEIVFTRGATEALNLLAYGLEHLIEAGDEIVISALEHHANLLPWQQLAKRRAAKLQVLPIDASGRIDLAAAAGLIGP
RTRLLAVSQLSNVLGCWQPLEPLLRLAKAQGALTVVDGAQGVVHGRHDMTTLGCDFYVLSSHKLYGPDGVGALYGRGESL
LQLRHWQFGGEMVRIADYQSAEFHAAPLGFEAGTPPISGVIGLGAALDYLAALDATAVGRHEQALHDLLLAGLAERSGIR
LLGAPQVALASFVVDGVHHSDLGHLLTEQGIAVRSGNHCAMPLMKHLGLDGATRVSLGLYNDHNDLQRFFDALDQALELL
R

Sequences:

>Translated_401_residues
MALFSPWRADFPALAVLEAQGQTYLDSAATAQKPQALIDALSGYYTCGAANVHRAQHQPAERATRAYEDARIKVAKWLNA
ACPTEIVFTRGATEALNLLAYGLEHLIEAGDEIVISALEHHANLLPWQQLAKRRAAKLQVLPIDASGRIDLAAAAGLIGP
RTRLLAVSQLSNVLGCWQPLEPLLRLAKAQGALTVVDGAQGVVHGRHDMTTLGCDFYVLSSHKLYGPDGVGALYGRGESL
LQLRHWQFGGEMVRIADYQSAEFHAAPLGFEAGTPPISGVIGLGAALDYLAALDATAVGRHEQALHDLLLAGLAERSGIR
LLGAPQVALASFVVDGVHHSDLGHLLTEQGIAVRSGNHCAMPLMKHLGLDGATRVSLGLYNDHNDLQRFFDALDQALELL
R
>Mature_400_residues
ALFSPWRADFPALAVLEAQGQTYLDSAATAQKPQALIDALSGYYTCGAANVHRAQHQPAERATRAYEDARIKVAKWLNAA
CPTEIVFTRGATEALNLLAYGLEHLIEAGDEIVISALEHHANLLPWQQLAKRRAAKLQVLPIDASGRIDLAAAAGLIGPR
TRLLAVSQLSNVLGCWQPLEPLLRLAKAQGALTVVDGAQGVVHGRHDMTTLGCDFYVLSSHKLYGPDGVGALYGRGESLL
QLRHWQFGGEMVRIADYQSAEFHAAPLGFEAGTPPISGVIGLGAALDYLAALDATAVGRHEQALHDLLLAGLAERSGIRL
LGAPQVALASFVVDGVHHSDLGHLLTEQGIAVRSGNHCAMPLMKHLGLDGATRVSLGLYNDHNDLQRFFDALDQALELLR

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=293, Percent_Identity=29.0102389078498, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI156713448, Length=347, Percent_Identity=25.0720461095101, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1789175, Length=404, Percent_Identity=44.5544554455446, Blast_Score=317, Evalue=6e-88,
Organism=Escherichia coli, GI1787970, Length=400, Percent_Identity=43, Blast_Score=304, Evalue=7e-84,
Organism=Escherichia coli, GI48994898, Length=397, Percent_Identity=26.9521410579345, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI25143064, Length=297, Percent_Identity=28.6195286195286, Blast_Score=111, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6319831, Length=392, Percent_Identity=27.0408163265306, Blast_Score=119, Evalue=8e-28,
Organism=Drosophila melanogaster, GI20129463, Length=263, Percent_Identity=31.5589353612167, Blast_Score=118, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 42940; Mature: 42808

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALFSPWRADFPALAVLEAQGQTYLDSAATAQKPQALIDALSGYYTCGAANVHRAQHQPA
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHCCEECCCCHHHHHHCCCH
ERATRAYEDARIKVAKWLNAACPTEIVFTRGATEALNLLAYGLEHLIEAGDEIVISALEH
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
HANLLPWQQLAKRRAAKLQVLPIDASGRIDLAAAAGLIGPRTRLLAVSQLSNVLGCWQPL
HCCCCCHHHHHHHHHCEEEEEEECCCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHCHHHH
EPLLRLAKAQGALTVVDGAQGVVHGRHDMTTLGCDFYVLSSHKLYGPDGVGALYGRGESL
HHHHHHHHCCCCEEEEECCCCCEECCCCCEEECCEEEEEECCCEECCCCCCHHHCCCHHH
LQLRHWQFGGEMVRIADYQSAEFHAAPLGFEAGTPPISGVIGLGAALDYLAALDATAVGR
HHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
HEQALHDLLLAGLAERSGIRLLGAPQVALASFVVDGVHHSDLGHLLTEQGIAVRSGNHCA
HHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCH
MPLMKHLGLDGATRVSLGLYNDHNDLQRFFDALDQALELLR
HHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
ALFSPWRADFPALAVLEAQGQTYLDSAATAQKPQALIDALSGYYTCGAANVHRAQHQPA
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHCCEECCCCHHHHHHCCCH
ERATRAYEDARIKVAKWLNAACPTEIVFTRGATEALNLLAYGLEHLIEAGDEIVISALEH
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
HANLLPWQQLAKRRAAKLQVLPIDASGRIDLAAAAGLIGPRTRLLAVSQLSNVLGCWQPL
HCCCCCHHHHHHHHHCEEEEEEECCCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHCHHHH
EPLLRLAKAQGALTVVDGAQGVVHGRHDMTTLGCDFYVLSSHKLYGPDGVGALYGRGESL
HHHHHHHHCCCCEEEEECCCCCEECCCCCEEECCEEEEEECCCEECCCCCCHHHCCCHHH
LQLRHWQFGGEMVRIADYQSAEFHAAPLGFEAGTPPISGVIGLGAALDYLAALDATAVGR
HHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
HEQALHDLLLAGLAERSGIRLLGAPQVALASFVVDGVHHSDLGHLLTEQGIAVRSGNHCA
HHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCH
MPLMKHLGLDGATRVSLGLYNDHNDLQRFFDALDQALELLR
HHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]