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The map label for this gene is htpX [H]

Identifier: 146282878

GI number: 146282878

Start: 2766032

End: 2766904

Strand: Direct

Name: htpX [H]

Synonym: PST_2539

Alternate gene names: 146282878

Gene position: 2766032-2766904 (Clockwise)

Preceding gene: 146282877

Following gene: 146282879

Centisome position: 60.56

GC content: 62.2

Gene sequence:

>873_bases
ATGATGCGCATTTTCTTGTTCCTGGCCACCAACCTTGCGGTCCTGGTCATCGCCAGCATCACCCTGAAGCTGCTCGGGGT
CGATCGCTACACCGGCCAGAACTATGGCAGCCTGCTGGTCTTCTGTGCGGTGTTCGGCTTTGCGGGATCGCTGATTTCGC
TGTTCATCTCCAAATGGATGGCGAAGATGAGCACACGCACGGAGATCATCAGCCAGCCGCGCACCCGCCATGAGCAGTGG
CTGCTGCAGACCGTCGAGCAACTGTCGCGCGAAGCCGGCATCAAGATGCCCGAGGTCGGTATCTTCCCGGCCTACGAGGC
CAACGCCTTCGCCACCGGATGGAATCGCAACGACGCGCTGGTAGCCGTCAGCCAGGGCCTGCTCGAACGTTTCTCCCCGG
ATGAAGTGCGCGCGGTGCTGGCGCATGAAATCGGCCACGTGGCCAATGGCGACATGGTCACCCTGGCGCTGATCCAGGGC
GTTGTGAACACCTTCGTCATGTTCTTTGCACGAATCTTCGGCAACTTCGTCGACAAGGCGATCCTCAAGAACGAGGACGG
CCATGGCATCGGCTACTTCGTCGCGACGATCTTCGCCGAACTGGTACTGGGCATCCTTGCCAGCATCATCGTCATGTGGT
TCTCGCGCAAGCGTGAATACCGCGCCGACGAAGCCGGCGCGCAACTGGCCGGCACCAGCGCCATGATCGGCGCCCTGCAG
CGCCTGCGGGCCGAACAGGGCCTGCCGGTGCACATGCCCGATTCGCTCAAGGCGTTCGGCATCAACGGCTCGCTCAAGCA
CGGCATGGCCGGCCTGTTCATGACCCATCCCTCTCTGGAGGATCGCATCGAAGCCCTGCGTCAGCGTGGCTGA

Upstream 100 bases:

>100_bases
CAAGCGACATAGCTTGAAATAGTCGCTCGGTTGAATAGCTCAAGGGCGCACCTTATATAGCCTATCGTTCTTCAAATCCT
ACCCTGGAGTCTGCCGCAAC

Downstream 100 bases:

>100_bases
GATCGACCGAGTGGTACCGGGGCGACGCAAGTCGCCCTTTTCGTTTGTCTATGCAGATTCAACTCCGCATAGAAGGAATC
GCCATGCGCCGCCTCATCTT

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MMRIFLFLATNLAVLVIASITLKLLGVDRYTGQNYGSLLVFCAVFGFAGSLISLFISKWMAKMSTRTEIISQPRTRHEQW
LLQTVEQLSREAGIKMPEVGIFPAYEANAFATGWNRNDALVAVSQGLLERFSPDEVRAVLAHEIGHVANGDMVTLALIQG
VVNTFVMFFARIFGNFVDKAILKNEDGHGIGYFVATIFAELVLGILASIIVMWFSRKREYRADEAGAQLAGTSAMIGALQ
RLRAEQGLPVHMPDSLKAFGINGSLKHGMAGLFMTHPSLEDRIEALRQRG

Sequences:

>Translated_290_residues
MMRIFLFLATNLAVLVIASITLKLLGVDRYTGQNYGSLLVFCAVFGFAGSLISLFISKWMAKMSTRTEIISQPRTRHEQW
LLQTVEQLSREAGIKMPEVGIFPAYEANAFATGWNRNDALVAVSQGLLERFSPDEVRAVLAHEIGHVANGDMVTLALIQG
VVNTFVMFFARIFGNFVDKAILKNEDGHGIGYFVATIFAELVLGILASIIVMWFSRKREYRADEAGAQLAGTSAMIGALQ
RLRAEQGLPVHMPDSLKAFGINGSLKHGMAGLFMTHPSLEDRIEALRQRG
>Mature_290_residues
MMRIFLFLATNLAVLVIASITLKLLGVDRYTGQNYGSLLVFCAVFGFAGSLISLFISKWMAKMSTRTEIISQPRTRHEQW
LLQTVEQLSREAGIKMPEVGIFPAYEANAFATGWNRNDALVAVSQGLLERFSPDEVRAVLAHEIGHVANGDMVTLALIQG
VVNTFVMFFARIFGNFVDKAILKNEDGHGIGYFVATIFAELVLGILASIIVMWFSRKREYRADEAGAQLAGTSAMIGALQ
RLRAEQGLPVHMPDSLKAFGINGSLKHGMAGLFMTHPSLEDRIEALRQRG

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=293, Percent_Identity=50.8532423208191, Blast_Score=272, Evalue=2e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 31968; Mature: 31968

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRIFLFLATNLAVLVIASITLKLLGVDRYTGQNYGSLLVFCAVFGFAGSLISLFISKWM
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AKMSTRTEIISQPRTRHEQWLLQTVEQLSREAGIKMPEVGIFPAYEANAFATGWNRNDAL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCHH
VAVSQGLLERFSPDEVRAVLAHEIGHVANGDMVTLALIQGVVNTFVMFFARIFGNFVDKA
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILKNEDGHGIGYFVATIFAELVLGILASIIVMWFSRKREYRADEAGAQLAGTSAMIGALQ
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCHHHHHHHHHHHHHH
RLRAEQGLPVHMPDSLKAFGINGSLKHGMAGLFMTHPSLEDRIEALRQRG
HHHHHCCCCEECCCCCCEECCCCCHHHCCHHHHEECCCHHHHHHHHHHCC
>Mature Secondary Structure
MMRIFLFLATNLAVLVIASITLKLLGVDRYTGQNYGSLLVFCAVFGFAGSLISLFISKWM
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AKMSTRTEIISQPRTRHEQWLLQTVEQLSREAGIKMPEVGIFPAYEANAFATGWNRNDAL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCCCCCCHH
VAVSQGLLERFSPDEVRAVLAHEIGHVANGDMVTLALIQGVVNTFVMFFARIFGNFVDKA
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILKNEDGHGIGYFVATIFAELVLGILASIIVMWFSRKREYRADEAGAQLAGTSAMIGALQ
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCHHHHHHHHHHHHHH
RLRAEQGLPVHMPDSLKAFGINGSLKHGMAGLFMTHPSLEDRIEALRQRG
HHHHHCCCCEECCCCCCEECCCCCHHHCCHHHHEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA