Click here to switch to the map view.

The map label for this gene is bdlA [H]

Identifier: 146282621

GI number: 146282621

Start: 2481062

End: 2482378

Strand: Direct

Name: bdlA [H]

Synonym: PST_2273

Alternate gene names: 146282621

Gene position: 2481062-2482378 (Clockwise)

Preceding gene: 146282620

Following gene: 146282622

Centisome position: 54.32

GC content: 62.72

Gene sequence:

>1317_bases
ATGTTCAACAAAAACCTAAAACGGGAACTGGCTGAGTTGCGCGAGGACGCGGCGATCAACCAGCAGATCAAGAACTCGTT
GTACAGGGAAATGATGGTCCTCGAATTGGACCCGCAAGGACGCATCCAGCACGCCAACGAGCTGTTCATCAGCGAAATGG
GCTATCGCCGCGAGGACCTTATCGGTCGTCCGCTCGATGGCTTCTTCAGCCAGCAGTTTCGTAGCGAACCGAACTATTCA
CGGCTCAAGACCGCCATGCAGCGTGCCGAGCATGTCAGCGGGGCGTACCGCCTGCTGCGTGCCGATGGCCAGGAAGCCTG
GCTGCGCTCCATCTGGCAACCGATCAAGGGCTCCGATGGCACGCTGCACCACTTCACCCTGTGCGCCACCAACCTGACCC
GCACCATCGAGACGTCACGCGAGCACGAGAGCGTGATCAATGCACTGCTGCGCTCCACCGCCGTCATCGAATTCGACCTG
GGCGGGCATGTCATCACGGCCAATCAGCGCTTCCTCGACGGCATGGGCTATCGCCTCGAGCAGATCAAGGGCAAGCACCA
CCGCATGTTCTGCGAACGCGAAGAGGCCGAATCCGCTGCCTACCGGGATTTCTGGGCCAGCCTGAACCGCGGCGAGTACA
TTGCGGACCGCTTCAAGCGCATCGATGCCCATGGCCGGACGGTCTGGCTGGAGGCTTCCTACAACCCGGTGCACGATGCC
TACGGCAAGCTCTACAAGGTCATCAAGTTCGCCACCGTGATCACCGATCAGGTCAACCGCGAGCTGGCCGTCGCCGAGGC
CGCGACCATCGCCTATGACACCTCGCACCACACTGATCTCAGTGCCCAGCGCGGCGCCCAGGTGGTCCAGCAGACCGTCG
ATGTGATGCATCGCATTGCCCAGCAGATGCAAGAGGCTTCCGATGGCATCGAGGCGCTGGACAAGCAGTCGCAGCTGATC
AGCGCCATTCTCAAGACCATCAGCGGGATCGCCGATCAGACCAACCTGCTGGCGCTCAACGCCGCCATCGAAGCTGCTCG
CGCCGGCGATCAGGGCCGCGGCTTCGCCGTAGTAGCCGACGAGGTGCGTCAGCTGGCCGCGCGCACCAGCAAGGCAGCCG
AGGAAATCGTCGGGGTGGTGCAGAAGAACCAGGACCTCGCCCAGGCTGCCGTGCACAGCATGTCCAGCAGCCGAGACCAG
GCCGAACAGGGCCTGGAATTCGCCAACCAGGCCGGCGCGGTCATCGTCGAGATCCAGGACGGCGCCCAGCGAGTGGTCAG
TGCGGTCGGCCAGTTCGCCAGTCAGCTGAAGAACTGA

Upstream 100 bases:

>100_bases
CGGAGGGATAGAACGAAGGGTGGCCACTGCGCCTCAGGAAAACTAGAACGGCGCCGATGCAGTGACTGGGCGGTCTTGCC
CTCCACTGGATGCCAAACAG

Downstream 100 bases:

>100_bases
TGGCGGGCTGCGCTCGGCCCAGCGCCTACACTTGCCGGCAGGCCCGAGCGCAATCGGGCGATGCATGTACCCGGCGGAGG
ATCAGCGCTTGAGCCAGAGG

Product: methyl-accepting chemotaxis transducer/sensory box protein

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MFNKNLKRELAELREDAAINQQIKNSLYREMMVLELDPQGRIQHANELFISEMGYRREDLIGRPLDGFFSQQFRSEPNYS
RLKTAMQRAEHVSGAYRLLRADGQEAWLRSIWQPIKGSDGTLHHFTLCATNLTRTIETSREHESVINALLRSTAVIEFDL
GGHVITANQRFLDGMGYRLEQIKGKHHRMFCEREEAESAAYRDFWASLNRGEYIADRFKRIDAHGRTVWLEASYNPVHDA
YGKLYKVIKFATVITDQVNRELAVAEAATIAYDTSHHTDLSAQRGAQVVQQTVDVMHRIAQQMQEASDGIEALDKQSQLI
SAILKTISGIADQTNLLALNAAIEAARAGDQGRGFAVVADEVRQLAARTSKAAEEIVGVVQKNQDLAQAAVHSMSSSRDQ
AEQGLEFANQAGAVIVEIQDGAQRVVSAVGQFASQLKN

Sequences:

>Translated_438_residues
MFNKNLKRELAELREDAAINQQIKNSLYREMMVLELDPQGRIQHANELFISEMGYRREDLIGRPLDGFFSQQFRSEPNYS
RLKTAMQRAEHVSGAYRLLRADGQEAWLRSIWQPIKGSDGTLHHFTLCATNLTRTIETSREHESVINALLRSTAVIEFDL
GGHVITANQRFLDGMGYRLEQIKGKHHRMFCEREEAESAAYRDFWASLNRGEYIADRFKRIDAHGRTVWLEASYNPVHDA
YGKLYKVIKFATVITDQVNRELAVAEAATIAYDTSHHTDLSAQRGAQVVQQTVDVMHRIAQQMQEASDGIEALDKQSQLI
SAILKTISGIADQTNLLALNAAIEAARAGDQGRGFAVVADEVRQLAARTSKAAEEIVGVVQKNQDLAQAAVHSMSSSRDQ
AEQGLEFANQAGAVIVEIQDGAQRVVSAVGQFASQLKN
>Mature_438_residues
MFNKNLKRELAELREDAAINQQIKNSLYREMMVLELDPQGRIQHANELFISEMGYRREDLIGRPLDGFFSQQFRSEPNYS
RLKTAMQRAEHVSGAYRLLRADGQEAWLRSIWQPIKGSDGTLHHFTLCATNLTRTIETSREHESVINALLRSTAVIEFDL
GGHVITANQRFLDGMGYRLEQIKGKHHRMFCEREEAESAAYRDFWASLNRGEYIADRFKRIDAHGRTVWLEASYNPVHDA
YGKLYKVIKFATVITDQVNRELAVAEAATIAYDTSHHTDLSAQRGAQVVQQTVDVMHRIAQQMQEASDGIEALDKQSQLI
SAILKTISGIADQTNLLALNAAIEAARAGDQGRGFAVVADEVRQLAARTSKAAEEIVGVVQKNQDLAQAAVHSMSSSRDQ
AEQGLEFANQAGAVIVEIQDGAQRVVSAVGQFASQLKN

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=133, Percent_Identity=42.1052631578947, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788195, Length=154, Percent_Identity=39.6103896103896, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI2367378, Length=154, Percent_Identity=40.2597402597403, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1787690, Length=109, Percent_Identity=48.6238532110092, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789453, Length=129, Percent_Identity=39.5348837209302, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 48969; Mature: 48969

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNKNLKRELAELREDAAINQQIKNSLYREMMVLELDPQGRIQHANELFISEMGYRREDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCHHHH
IGRPLDGFFSQQFRSEPNYSRLKTAMQRAEHVSGAYRLLRADGQEAWLRSIWQPIKGSDG
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
TLHHFTLCATNLTRTIETSREHESVINALLRSTAVIEFDLGGHVITANQRFLDGMGYRLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEECCHHHHHHHHHHHH
QIKGKHHRMFCEREEAESAAYRDFWASLNRGEYIADRFKRIDAHGRTVWLEASYNPVHDA
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHH
YGKLYKVIKFATVITDQVNRELAVAEAATIAYDTSHHTDLSAQRGAQVVQQTVDVMHRIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
QQMQEASDGIEALDKQSQLISAILKTISGIADQTNLLALNAAIEAARAGDQGRGFAVVAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEHHHH
EVRQLAARTSKAAEEIVGVVQKNQDLAQAAVHSMSSSRDQAEQGLEFANQAGAVIVEIQD
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECC
GAQRVVSAVGQFASQLKN
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFNKNLKRELAELREDAAINQQIKNSLYREMMVLELDPQGRIQHANELFISEMGYRREDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHCCCHHHH
IGRPLDGFFSQQFRSEPNYSRLKTAMQRAEHVSGAYRLLRADGQEAWLRSIWQPIKGSDG
CCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
TLHHFTLCATNLTRTIETSREHESVINALLRSTAVIEFDLGGHVITANQRFLDGMGYRLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEECCHHHHHHHHHHHH
QIKGKHHRMFCEREEAESAAYRDFWASLNRGEYIADRFKRIDAHGRTVWLEASYNPVHDA
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHH
YGKLYKVIKFATVITDQVNRELAVAEAATIAYDTSHHTDLSAQRGAQVVQQTVDVMHRIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
QQMQEASDGIEALDKQSQLISAILKTISGIADQTNLLALNAAIEAARAGDQGRGFAVVAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEHHHH
EVRQLAARTSKAAEEIVGVVQKNQDLAQAAVHSMSSSRDQAEQGLEFANQAGAVIVEIQD
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECC
GAQRVVSAVGQFASQLKN
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]