Click here to switch to the map view.

The map label for this gene is fhuA [H]

Identifier: 145301185

GI number: 145301185

Start: 4667676

End: 4669781

Strand: Direct

Name: fhuA [H]

Synonym: ASA_4363

Alternate gene names: 145301185

Gene position: 4667676-4669781 (Clockwise)

Preceding gene: 145301169

Following gene: 145301186

Centisome position: 99.26

GC content: 59.07

Gene sequence:

>2106_bases
ATGATTGCGCAAAAAAACACCCTGACCGCAGCGATGCGAAATAGAGGGGCACAGCAACTGCTGCCGCTCTCCTGCCTGCT
GGCAAGCCTGCCAGTACTGGCCGAACAACCGAAAGAATTGCCAAAAGCCAGCGAAACCATGGTGGTGACAGGTACCGCCA
TGAAGGTGGAAGTGCCCATGGCCGAGACGCCAAGGGCCGTCTCAGTGGTCAATCGTGAGGAACTGGATCAGCACGCCGTG
CTGAAACTGGACGAAGCGCTGCGCTACCGCTCCGGTGTGCTCTCCCAATCCTATGGATCCGACAACGATGCTGACTGGTT
CAAGGTGCGTGGCTTCGATGCCGCCTCCTATCTGGATGGCAATCGCCTGTTCAGCACCGGCTACTATGTGTGGACGCCAG
AGCCGTTCGGTCTGGAAAGCGTGGAAGTGCTGAAAGGGCCCGCCTCGATCCTCTACGGCGAGGCGCCTCCCGGCGGCGTG
ATCAATGCCATCAGCAAGCGGCCGACTGCCACCCCGCAGGGGCAGCTGGATCTGCAGATGGGCTGCCGGGATCTTCGCCA
GATCGGGGTGGATGTCTCGGATGCATTGACCGACAACAGTCGCTACCGTCTGGTCGCCCTCTATAGCGAGCGTGACGGCG
TGCTGAACGATACCTATAACGATAGGGTTTATCTGGCGCCAAGCGTCACCCTGGATATCTCGGATCGTACCAGCCTGACC
CTGCTGGCCAGTTTCAAGCATGACGAAGGTGTGCCGACCAACGGCTTCTTCCCTGTCTATGGCACTCTCAATACCAGCGG
TGGCCAGATTGATCCCTCCACCAACCTGAGCCAGCCGGATTACGATCGCAATCGCAACACCCAGATCTCCGCCGGTTACG
AGCTGGCCCACCAGCTCAACCAGACCTGGGAATTCAAGCAGAACGTCCGCTTCAACTACAACGATCTGCTGCTGCGCCAG
ACCTATATCTTCCCGACCTATGAAGGCACGACCGCCTACCGTGGGCTGGTCTACCGGGATGGCGACACCAAGAGCGCCAC
CATGGATAACCAGATGGTGGGTTACTGGAACACGGACAGCACGGAGCAGACCTTGCTGCTGGGGCTGGATCTGCAGCGTC
ACGTCAACGAAGGTCAGGAAGCCGATAACTTCGGCATGGGTTCCATCAATACCATGAACCCGGATTACAGCGGCTTCCCC
GGTTTTGACGAATCCACCACCATCCACCAGAAGAGCACCAAGGGCCAGAGCGGCCTCTATGCCCAGCACCAGATCCGCTG
GGACGATCGCTGGTTGCTGACCGGTGGTGGCCGCTTCGACTATGTGGAGACCCACAACATCAGCGAAGCCAAGAGCAAGG
AGGAGAAACAGTACGATCACGAGCTATCCCTCTCCGGCAGCCTGATGTATCTGGCCGACAACGGTCTCTCTCCTTATATT
GCCTACGCCGAATCGTTCGAGGTGTTGCCCGGGATAGATCCCAATACCCAGAACTCCTACAAGCCGCTCAAGGGCACCCT
GTATGAGACTGGCGTCAAGTACGCCCCCAGCTTCCTAGACGGTTACATCAATCTGGCCCTGTTCGATCTGGAGCAGACCA
ACTCGCTCGTCTCTACAGGATCCGGTCAGCAGACCCAGGCCGGCGAAGTGACCTCCCAGGGTGTCGAGCTGGAAGGCAGC
GTGCAGGCCACAGAGGCGCTGCGTCTCACCGCTGCTTATACCTACACGGATGCCAAGACCAACGACACCGGCAAGGGTGA
TCGCCGTGCCAGCCTGATCCCGCGCCATATCGCCTCCTTCTGGGGCAACTACAAGGTGCAGCAGGGAGTTGCTTCCGGTC
TGGAACTGCGAACCGGCGTACGTTATGTCGGCTCCAGTGTCGGCATAGGCGCCGTGGATGCCAGCTACAACCCCATCTAT
GGTTCGGCCCAGGTACCGGCCCATACCGTATGGGATGCGATGATCGGGTATGACTTTGCCAAGAACTGGCGAGCCCAGCT
CAACGTCAACAACCTGCTGGGTGAAACCTACGTGGCCAGCTGTGACTACTACTGCTACTACGGCGAGCCGCGCAGTGTGG
TGGGCAGCATCAACTACCGCTGGTAA

Upstream 100 bases:

>100_bases
ATTGCGCTGCTTTATTCGCCTGAGGAACCGGGCAGACCAGCTTGATCGGTCACCAATAATAAGAAACCAGAAACAACTCA
TTGATATTTGAGACACTTAT

Downstream 100 bases:

>100_bases
CAGAGGTCGGGCGGGAGTCGTGACTTCCGCCCTTTTTTCCCCGCATACAGGCCCGTCATGGAACTCTTGTCTCTGGTTTA
CCGCCAATATCGTTGGCCCT

Product: hydroxamate-type ferric siderophore receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 701; Mature: 701

Protein sequence:

>701_residues
MIAQKNTLTAAMRNRGAQQLLPLSCLLASLPVLAEQPKELPKASETMVVTGTAMKVEVPMAETPRAVSVVNREELDQHAV
LKLDEALRYRSGVLSQSYGSDNDADWFKVRGFDAASYLDGNRLFSTGYYVWTPEPFGLESVEVLKGPASILYGEAPPGGV
INAISKRPTATPQGQLDLQMGCRDLRQIGVDVSDALTDNSRYRLVALYSERDGVLNDTYNDRVYLAPSVTLDISDRTSLT
LLASFKHDEGVPTNGFFPVYGTLNTSGGQIDPSTNLSQPDYDRNRNTQISAGYELAHQLNQTWEFKQNVRFNYNDLLLRQ
TYIFPTYEGTTAYRGLVYRDGDTKSATMDNQMVGYWNTDSTEQTLLLGLDLQRHVNEGQEADNFGMGSINTMNPDYSGFP
GFDESTTIHQKSTKGQSGLYAQHQIRWDDRWLLTGGGRFDYVETHNISEAKSKEEKQYDHELSLSGSLMYLADNGLSPYI
AYAESFEVLPGIDPNTQNSYKPLKGTLYETGVKYAPSFLDGYINLALFDLEQTNSLVSTGSGQQTQAGEVTSQGVELEGS
VQATEALRLTAAYTYTDAKTNDTGKGDRRASLIPRHIASFWGNYKVQQGVASGLELRTGVRYVGSSVGIGAVDASYNPIY
GSAQVPAHTVWDAMIGYDFAKNWRAQLNVNNLLGETYVASCDYYCYYGEPRSVVGSINYRW

Sequences:

>Translated_701_residues
MIAQKNTLTAAMRNRGAQQLLPLSCLLASLPVLAEQPKELPKASETMVVTGTAMKVEVPMAETPRAVSVVNREELDQHAV
LKLDEALRYRSGVLSQSYGSDNDADWFKVRGFDAASYLDGNRLFSTGYYVWTPEPFGLESVEVLKGPASILYGEAPPGGV
INAISKRPTATPQGQLDLQMGCRDLRQIGVDVSDALTDNSRYRLVALYSERDGVLNDTYNDRVYLAPSVTLDISDRTSLT
LLASFKHDEGVPTNGFFPVYGTLNTSGGQIDPSTNLSQPDYDRNRNTQISAGYELAHQLNQTWEFKQNVRFNYNDLLLRQ
TYIFPTYEGTTAYRGLVYRDGDTKSATMDNQMVGYWNTDSTEQTLLLGLDLQRHVNEGQEADNFGMGSINTMNPDYSGFP
GFDESTTIHQKSTKGQSGLYAQHQIRWDDRWLLTGGGRFDYVETHNISEAKSKEEKQYDHELSLSGSLMYLADNGLSPYI
AYAESFEVLPGIDPNTQNSYKPLKGTLYETGVKYAPSFLDGYINLALFDLEQTNSLVSTGSGQQTQAGEVTSQGVELEGS
VQATEALRLTAAYTYTDAKTNDTGKGDRRASLIPRHIASFWGNYKVQQGVASGLELRTGVRYVGSSVGIGAVDASYNPIY
GSAQVPAHTVWDAMIGYDFAKNWRAQLNVNNLLGETYVASCDYYCYYGEPRSVVGSINYRW
>Mature_701_residues
MIAQKNTLTAAMRNRGAQQLLPLSCLLASLPVLAEQPKELPKASETMVVTGTAMKVEVPMAETPRAVSVVNREELDQHAV
LKLDEALRYRSGVLSQSYGSDNDADWFKVRGFDAASYLDGNRLFSTGYYVWTPEPFGLESVEVLKGPASILYGEAPPGGV
INAISKRPTATPQGQLDLQMGCRDLRQIGVDVSDALTDNSRYRLVALYSERDGVLNDTYNDRVYLAPSVTLDISDRTSLT
LLASFKHDEGVPTNGFFPVYGTLNTSGGQIDPSTNLSQPDYDRNRNTQISAGYELAHQLNQTWEFKQNVRFNYNDLLLRQ
TYIFPTYEGTTAYRGLVYRDGDTKSATMDNQMVGYWNTDSTEQTLLLGLDLQRHVNEGQEADNFGMGSINTMNPDYSGFP
GFDESTTIHQKSTKGQSGLYAQHQIRWDDRWLLTGGGRFDYVETHNISEAKSKEEKQYDHELSLSGSLMYLADNGLSPYI
AYAESFEVLPGIDPNTQNSYKPLKGTLYETGVKYAPSFLDGYINLALFDLEQTNSLVSTGSGQQTQAGEVTSQGVELEGS
VQATEALRLTAAYTYTDAKTNDTGKGDRRASLIPRHIASFWGNYKVQQGVASGLELRTGVRYVGSSVGIGAVDASYNPIY
GSAQVPAHTVWDAMIGYDFAKNWRAQLNVNNLLGETYVASCDYYCYYGEPRSVVGSINYRW

Specific function: Involved in the initial step of iron uptake by binding chrysobactin, an iron chelatin siderophore that allows the bacteria to extract iron from the environment [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=710, Percent_Identity=31.5492957746479, Blast_Score=308, Evalue=7e-85,
Organism=Escherichia coli, GI1787024, Length=728, Percent_Identity=25.8241758241758, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1788478, Length=180, Percent_Identity=30.5555555555556, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 77551; Mature: 77551

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAQKNTLTAAMRNRGAQQLLPLSCLLASLPVLAEQPKELPKASETMVVTGTAMKVEVPM
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHCHHHCCCCCCEEEEEECEEEEEECC
AETPRAVSVVNREELDQHAVLKLDEALRYRSGVLSQSYGSDNDADWFKVRGFDAASYLDG
CCCCCCEEHHCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHCCCC
NRLFSTGYYVWTPEPFGLESVEVLKGPASILYGEAPPGGVINAISKRPTATPQGQLDLQM
CEEEECCEEEECCCCCCCCHHHHHCCCCCEEECCCCCCHHHHHHCCCCCCCCCCCEEHHH
GCRDLRQIGVDVSDALTDNSRYRLVALYSERDGVLNDTYNDRVYLAPSVTLDISDRTSLT
HHHHHHHHCCCHHHHHCCCCCEEEEEEEECCCCCCCCCCCCEEEECCEEEEEECCCCCEE
LLASFKHDEGVPTNGFFPVYGTLNTSGGQIDPSTNLSQPDYDRNRNTQISAGYELAHQLN
EEEECCCCCCCCCCCEEEEEEEEECCCCEECCCCCCCCCCCCCCCCCEEECHHHHHHHHC
QTWEFKQNVRFNYNDLLLRQTYIFPTYEGTTAYRGLVYRDGDTKSATMDNQMVGYWNTDS
CCHHHHCCCCCCCCCEEEEEEEEEECCCCCCHHCEEEEECCCCCCCCCCCCEEEEECCCC
TEQTLLLGLDLQRHVNEGQEADNFGMGSINTMNPDYSGFPGFDESTTIHQKSTKGQSGLY
CCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCE
AQHQIRWDDRWLLTGGGRFDYVETHNISEAKSKEEKQYDHELSLSGSLMYLADNGLSPYI
EEEEEEECCEEEEECCCEEEEEECCCCHHHHHHHHHHHCCEECCCCCEEEEECCCCCCEE
AYAESFEVLPGIDPNTQNSYKPLKGTLYETGVKYAPSFLDGYINLALFDLEQTNSLVSTG
EECCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHCHHHHCCEEEEEEEEEHHCCCHHCCC
SGQQTQAGEVTSQGVELEGSVQATEALRLTAAYTYTDAKTNDTGKGDRRASLIPRHIASF
CCCCCCCCCHHHCCEEECCCCCHHHEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
WGNYKVQQGVASGLELRTGVRYVGSSVGIGAVDASYNPIYGSAQVPAHTVWDAMIGYDFA
HCCCEEHHHHHCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
KNWRAQLNVNNLLGETYVASCDYYCYYGEPRSVVGSINYRW
CCCEEEEEHHHHCCCCEEECCCEEEEECCCCCEEEECCCCC
>Mature Secondary Structure
MIAQKNTLTAAMRNRGAQQLLPLSCLLASLPVLAEQPKELPKASETMVVTGTAMKVEVPM
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHCHHHCCCCCCEEEEEECEEEEEECC
AETPRAVSVVNREELDQHAVLKLDEALRYRSGVLSQSYGSDNDADWFKVRGFDAASYLDG
CCCCCCEEHHCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHCCCC
NRLFSTGYYVWTPEPFGLESVEVLKGPASILYGEAPPGGVINAISKRPTATPQGQLDLQM
CEEEECCEEEECCCCCCCCHHHHHCCCCCEEECCCCCCHHHHHHCCCCCCCCCCCEEHHH
GCRDLRQIGVDVSDALTDNSRYRLVALYSERDGVLNDTYNDRVYLAPSVTLDISDRTSLT
HHHHHHHHCCCHHHHHCCCCCEEEEEEEECCCCCCCCCCCCEEEECCEEEEEECCCCCEE
LLASFKHDEGVPTNGFFPVYGTLNTSGGQIDPSTNLSQPDYDRNRNTQISAGYELAHQLN
EEEECCCCCCCCCCCEEEEEEEEECCCCEECCCCCCCCCCCCCCCCCEEECHHHHHHHHC
QTWEFKQNVRFNYNDLLLRQTYIFPTYEGTTAYRGLVYRDGDTKSATMDNQMVGYWNTDS
CCHHHHCCCCCCCCCEEEEEEEEEECCCCCCHHCEEEEECCCCCCCCCCCCEEEEECCCC
TEQTLLLGLDLQRHVNEGQEADNFGMGSINTMNPDYSGFPGFDESTTIHQKSTKGQSGLY
CCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCE
AQHQIRWDDRWLLTGGGRFDYVETHNISEAKSKEEKQYDHELSLSGSLMYLADNGLSPYI
EEEEEEECCEEEEECCCEEEEEECCCCHHHHHHHHHHHCCEECCCCCEEEEECCCCCCEE
AYAESFEVLPGIDPNTQNSYKPLKGTLYETGVKYAPSFLDGYINLALFDLEQTNSLVSTG
EECCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHCHHHHCCEEEEEEEEEHHCCCHHCCC
SGQQTQAGEVTSQGVELEGSVQATEALRLTAAYTYTDAKTNDTGKGDRRASLIPRHIASF
CCCCCCCCCHHHCCEEECCCCCHHHEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
WGNYKVQQGVASGLELRTGVRYVGSSVGIGAVDASYNPIYGSAQVPAHTVWDAMIGYDFA
HCCCEEHHHHHCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
KNWRAQLNVNNLLGETYVASCDYYCYYGEPRSVVGSINYRW
CCCEEEEEHHHHCCCCEEECCCEEEEECCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8576065 [H]