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The map label for this gene is glnL [H]

Identifier: 145300969

GI number: 145300969

Start: 4414477

End: 4415532

Strand: Direct

Name: glnL [H]

Synonym: ASA_4122

Alternate gene names: 145300969

Gene position: 4414477-4415532 (Clockwise)

Preceding gene: 145300968

Following gene: 145300970

Centisome position: 93.88

GC content: 60.13

Gene sequence:

>1056_bases
GTGCCAACCCGCCCGGATCAAGCCAAGATACTGCTCGATAACTTGCTGACCGCCGTCATCCTGATGGATGAGCGGCTCTG
CATCCAGTTCGTCAACCCGGCGGCCGAACAACTGCTCTCCCTCAGCCAGCCTCGGCTGATCGGGATCGAGCTGCCCCACC
TGCTGGAACATATCTCTCTCGATTTGCAGCGCCTCAAGCAATGCCTTACCTCTGGGCAGGGCTTCACCGACAGTGAAGTG
ACCCTGGTGGTGGAAGGTGAACCCAGGCTGCTGGAGATGAGCGTAAGCCCGCTTGCCGACCATGAACAACGGCTGATGGT
GGTAGAGCTGCGCAAAATTGATCAGCAGAAGAAGATCAGCCAGGAGCTGCAACAACATGCCCAGCAACAGGCGGCCAAGG
AACTGGTGCGCGGACTGGCCCACGAGATCAAGAACCCGCTGGGCGGCCTGCGCGGCGCGGCTCAGCTGCTGCAAAAAGAG
CTACCGGATCCGGCCTTGCGCGAATACACGGGCATCATCATAGAGCAGGCCGACCGGCTGAGGGTGCTGGTCGATCGCCT
GCTCGGCCCCCAGCGTCCGGGTCGCCACCAGATGCACAATGTCCACTCCGTGCTGGAGCAGGTGCGCCGTCTGGTGGAGC
TGGAGCTGCCACCCACTGTGCGCATAGAGCGGGATTACGATCCCAGCATTCCCGAGTTCGAGATGGAGCCGGATCATCTG
CAGCAAGCCTTTCTCAACATGGTTCGCAACGCCGCCGAAGCCATAGGTGAACAGATGGGACTGATTCGCATCAAAACCCG
CACCTCCTTCCAGATCACCATCCATGGTCAGCGCTACCGGCTGGCGGCCGAGATCAAGATCATCGACAACGGCCCCGGCA
TTCCCGATGCCATCCGCGACACCCTCTTCTACCCCATGATCACCGGCAAGGAGGGGGGAACCGGACTCGGCCTCTCCATC
GCCCAGAATCTGATTGATCAGCACAAGGGGCGTATCGACTGCATCAGCTGGCCTGGTCACACCGAATTCACCATTTTTCT
ACCGCTTCGCAAATAA

Upstream 100 bases:

>100_bases
CGCTCCCCAACAAGGGGTGATCCTGTGCATCGATACGGGTAGACTAAATGCACCACGTTGGTGCATTACTGGTGTATAGC
ACCGTTTTAGGGAGAAACCT

Downstream 100 bases:

>100_bases
GGGAACGTCATGACAGCAAAAGTGTGGATCGTCGATGACGACAGTTCTATCCGCTGGGTACTGGAACGCACCCTCGGCAG
TGAAGGCTTCGAGTGCGAGA

Product: nitrogen regulation protein NR(II)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MPTRPDQAKILLDNLLTAVILMDERLCIQFVNPAAEQLLSLSQPRLIGIELPHLLEHISLDLQRLKQCLTSGQGFTDSEV
TLVVEGEPRLLEMSVSPLADHEQRLMVVELRKIDQQKKISQELQQHAQQQAAKELVRGLAHEIKNPLGGLRGAAQLLQKE
LPDPALREYTGIIIEQADRLRVLVDRLLGPQRPGRHQMHNVHSVLEQVRRLVELELPPTVRIERDYDPSIPEFEMEPDHL
QQAFLNMVRNAAEAIGEQMGLIRIKTRTSFQITIHGQRYRLAAEIKIIDNGPGIPDAIRDTLFYPMITGKEGGTGLGLSI
AQNLIDQHKGRIDCISWPGHTEFTIFLPLRK

Sequences:

>Translated_351_residues
MPTRPDQAKILLDNLLTAVILMDERLCIQFVNPAAEQLLSLSQPRLIGIELPHLLEHISLDLQRLKQCLTSGQGFTDSEV
TLVVEGEPRLLEMSVSPLADHEQRLMVVELRKIDQQKKISQELQQHAQQQAAKELVRGLAHEIKNPLGGLRGAAQLLQKE
LPDPALREYTGIIIEQADRLRVLVDRLLGPQRPGRHQMHNVHSVLEQVRRLVELELPPTVRIERDYDPSIPEFEMEPDHL
QQAFLNMVRNAAEAIGEQMGLIRIKTRTSFQITIHGQRYRLAAEIKIIDNGPGIPDAIRDTLFYPMITGKEGGTGLGLSI
AQNLIDQHKGRIDCISWPGHTEFTIFLPLRK
>Mature_350_residues
PTRPDQAKILLDNLLTAVILMDERLCIQFVNPAAEQLLSLSQPRLIGIELPHLLEHISLDLQRLKQCLTSGQGFTDSEVT
LVVEGEPRLLEMSVSPLADHEQRLMVVELRKIDQQKKISQELQQHAQQQAAKELVRGLAHEIKNPLGGLRGAAQLLQKEL
PDPALREYTGIIIEQADRLRVLVDRLLGPQRPGRHQMHNVHSVLEQVRRLVELELPPTVRIERDYDPSIPEFEMEPDHLQ
QAFLNMVRNAAEAIGEQMGLIRIKTRTSFQITIHGQRYRLAAEIKIIDNGPGIPDAIRDTLFYPMITGKEGGTGLGLSIA
QNLIDQHKGRIDCISWPGHTEFTIFLPLRK

Specific function: NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC. In nitrogen limitation ntrB activates ntrC by phosphorylating it, while in nitrogen excess ntrC is dephosphorylated and consequently inactiva

COG id: COG3852

COG function: function code T; Signal transduction histidine kinase, nitrogen specific

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790300, Length=349, Percent_Identity=57.0200573065903, Blast_Score=417, Evalue=1e-118,
Organism=Escherichia coli, GI1788549, Length=348, Percent_Identity=28.1609195402299, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=28.6885245901639, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786600, Length=351, Percent_Identity=27.6353276353276, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789808, Length=206, Percent_Identity=27.6699029126214, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790861, Length=237, Percent_Identity=26.1603375527426, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39698; Mature: 39567

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTRPDQAKILLDNLLTAVILMDERLCIQFVNPAAEQLLSLSQPRLIGIELPHLLEHISL
CCCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHCCCCCEEECCHHHHHHHHHH
DLQRLKQCLTSGQGFTDSEVTLVVEGEPRLLEMSVSPLADHEQRLMVVELRKIDQQKKIS
HHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
QELQQHAQQQAAKELVRGLAHEIKNPLGGLRGAAQLLQKELPDPALREYTGIIIEQADRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RVLVDRLLGPQRPGRHQMHNVHSVLEQVRRLVELELPPTVRIERDYDPSIPEFEMEPDHL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHH
QQAFLNMVRNAAEAIGEQMGLIRIKTRTSFQITIHGQRYRLAAEIKIIDNGPGIPDAIRD
HHHHHHHHHHHHHHHHHHCCEEEEEECCEEEEEEECCEEEEEEEEEEEECCCCCHHHHHH
TLFYPMITGKEGGTGLGLSIAQNLIDQHKGRIDCISWPGHTEFTIFLPLRK
HHHHCEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCC
>Mature Secondary Structure 
PTRPDQAKILLDNLLTAVILMDERLCIQFVNPAAEQLLSLSQPRLIGIELPHLLEHISL
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHCCCCCEEECCHHHHHHHHHH
DLQRLKQCLTSGQGFTDSEVTLVVEGEPRLLEMSVSPLADHEQRLMVVELRKIDQQKKIS
HHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
QELQQHAQQQAAKELVRGLAHEIKNPLGGLRGAAQLLQKELPDPALREYTGIIIEQADRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RVLVDRLLGPQRPGRHQMHNVHSVLEQVRRLVELELPPTVRIERDYDPSIPEFEMEPDHL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHH
QQAFLNMVRNAAEAIGEQMGLIRIKTRTSFQITIHGQRYRLAAEIKIIDNGPGIPDAIRD
HHHHHHHHHHHHHHHHHHCCEEEEEECCEEEEEEECCEEEEEEEEEEEECCCCCHHHHHH
TLFYPMITGKEGGTGLGLSIAQNLIDQHKGRIDCISWPGHTEFTIFLPLRK
HHHHCEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2574025 [H]