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The map label for this gene is hlyB [H]

Identifier: 145300865

GI number: 145300865

Start: 4305044

End: 4307038

Strand: Direct

Name: hlyB [H]

Synonym: ASA_4010

Alternate gene names: 145300865

Gene position: 4305044-4307038 (Clockwise)

Preceding gene: 145300864

Following gene: 145300868

Centisome position: 91.55

GC content: 62.96

Gene sequence:

>1995_bases
ATGGGGTGGAGTCTGGGAACAATCAAGGGACGATATACAGCCGTCTTCGTGGGATTCATGGTGCTGGTGTGCGCCCTGAC
GGTCATCGGCATCCAGATCTGGATCAAGCCGGCGCTGCAAAAGGCCGGTGAACAGAATGTGACGCTGCTGGTCAGCGAGA
TCGCCACCGACATCCTCGATGAGCTCAACGGCGTACAGAGCCAGTCCCGCAGCATCACCCAGCTGGTCGCCCAGCTGCCA
AGCGAGCAAATTGATGCCCTGCTGCCTGCGCTGATCGATCAATATGGCAATGCCATGGTGTTTGGCGGCGGCATCTGGCC
GCTGCCGGATCAACGGGAAGCGGGCCGCGCCAAGTTCAGCACCTTCTTTCACAGGGATGCGGCCAACAAGCTGATCCCCA
ACACCTACTGGAACTCGGCCGAGGCCCCCAACTACTTCGAACAGCCCTGGCACAAGGCGGGGCAACAGGCTCCCCAGGGC
ATGTGCGTCTGGGCGGCGGCCTACAAGGACGGTGCCAGCCAGCAGCCGAGAACCAACTGCGCCATGGGGATCTATCGCAA
CGGCGCCCTGTTCGGGGTATCGACCATAGATGTGACCCTGGGTTTCTTCAACGATCTGGTGGCCAGGAAAGAGCAGGAGA
TCGGGGGCCAGGTGATGATCATCGAGGCTGACGGCAAGATCCTGAGCAAGAATGCCCGTCTGAACGGGGATGTTGTGCTG
GGCAACCTCTCGGCTCACGCCGATTACCCCTTCGCTGGTGCCATCGCCAGCCTGATCGGCCAGAGCCGGGGTACAGGGCT
GTTGCGCACCACTTTCCAGGATCAGGGGCAGGAACAGACATTGCTGCTGCAGGCCATAGAGGGGACCCCCTGGTTGCTGG
CCACCGCCCTGCCAACCAGCACCCTGACCCAGGACAGCCAGGACGTGCTCACCACGCTGGCCGCAATTCAGCTGCCCCTG
GTCGGACTACTGTTCGTGCTGATGCTGCTGGCCATCACTCAGCTCGGCAGCCGCTTGCAGACACTCAAACAGAATATCGA
CGCCCTCTCCACCGGCGATGCCGACCTGACCGCCCGCATCCAGGTGAAGGGGAATGACGAGCTGGATCATATCGCCCTGT
CGGTGAACCGCTTCATCGCCTATTTGCAGCAGATGATGGTGCAGGTGACTGACGCCACCGACCTCATCACCCGCGAACTG
GCACAGCTCGATCAGCAGACGGGTCAGGCAAGACGGATCCTGGGTGAACATGCCGCCGAAACGGATCAGGTGGTCACCGC
CCTCACCGAGCTCAGCTCCACCGCCGACAGCGTGGCACAACACGCTAGCGACTCGGCCAGCTTCACCGAAGCCGCCAACG
GCCAGGCAGCCAATTCACGCAAGGTAGTGGGATCGGCCTCCGCCAGCGTAGTAGCCCTGATCGACGACGTGGATCTCGCC
GCCGCCAAGGTGCTGGAGATGCAGGAAGATGCCAAGCAGATTGGCAGCGTGCTCGGGGTGATAGGTGGCATCGCCGCCCA
GACCAACTTGCTGGCGCTCAATGCCGCCATCGAAGCGGCGCGGGCCGGTGAGCAGGGCCGCGGTTTCGCTGTGGTGGCTG
ACGAAGTGCGTGCCCTGGCGGCTCGTACCCAGAAGAGCACCGCCGAGGTGGGCAGCATGCTGTCGCGCCTCACTCAGGGG
GTGGCCGATGCCGTCGTCGCCATGGAGCAGACCAAACGCAGCTGTCAGGCCGCGGCAGATACCACTGGGCAGGTGACTGG
GGGGCTCGACAGCATGGCCGACTCAGTGGTGCAGATCCACGATCTCAGCAGCCAGATCGCCACCGCCGCCGAGGAGCAGA
GCCGGGTGACAGAGGAGATCAACCGCAACATGGTGAGCATCCGCGACATGCTCAACCTGCTGGTAGAAAATGGCCGCAAC
ACGGAGCAGAGCGCCGAGTCGCTGCTCAGCTCCAACCGCCAGTTGCTGGCCCTGGTGCGTCGCTTCAAGGTGTGA

Upstream 100 bases:

>100_bases
CTGTGAGCGATAACAAACGTTTTATGTTCGAAATGGCTAATAATAGCGACTCAAACAACAAGGTCACGCAAGACAGTGCC
AACAACAGACAGGAGTCGTT

Downstream 100 bases:

>100_bases
TCATGAACGTCAGCCAGCAAAAAGGGGCCATCAGGCCCTTTTTCATGCACGTCACTCAGACTCAACCTTGGCTTTGTCGG
CCAGGTTCAGGGTCTTGACG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 664; Mature: 663

Protein sequence:

>664_residues
MGWSLGTIKGRYTAVFVGFMVLVCALTVIGIQIWIKPALQKAGEQNVTLLVSEIATDILDELNGVQSQSRSITQLVAQLP
SEQIDALLPALIDQYGNAMVFGGGIWPLPDQREAGRAKFSTFFHRDAANKLIPNTYWNSAEAPNYFEQPWHKAGQQAPQG
MCVWAAAYKDGASQQPRTNCAMGIYRNGALFGVSTIDVTLGFFNDLVARKEQEIGGQVMIIEADGKILSKNARLNGDVVL
GNLSAHADYPFAGAIASLIGQSRGTGLLRTTFQDQGQEQTLLLQAIEGTPWLLATALPTSTLTQDSQDVLTTLAAIQLPL
VGLLFVLMLLAITQLGSRLQTLKQNIDALSTGDADLTARIQVKGNDELDHIALSVNRFIAYLQQMMVQVTDATDLITREL
AQLDQQTGQARRILGEHAAETDQVVTALTELSSTADSVAQHASDSASFTEAANGQAANSRKVVGSASASVVALIDDVDLA
AAKVLEMQEDAKQIGSVLGVIGGIAAQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAARTQKSTAEVGSMLSRLTQG
VADAVVAMEQTKRSCQAAADTTGQVTGGLDSMADSVVQIHDLSSQIATAAEEQSRVTEEINRNMVSIRDMLNLLVENGRN
TEQSAESLLSSNRQLLALVRRFKV

Sequences:

>Translated_664_residues
MGWSLGTIKGRYTAVFVGFMVLVCALTVIGIQIWIKPALQKAGEQNVTLLVSEIATDILDELNGVQSQSRSITQLVAQLP
SEQIDALLPALIDQYGNAMVFGGGIWPLPDQREAGRAKFSTFFHRDAANKLIPNTYWNSAEAPNYFEQPWHKAGQQAPQG
MCVWAAAYKDGASQQPRTNCAMGIYRNGALFGVSTIDVTLGFFNDLVARKEQEIGGQVMIIEADGKILSKNARLNGDVVL
GNLSAHADYPFAGAIASLIGQSRGTGLLRTTFQDQGQEQTLLLQAIEGTPWLLATALPTSTLTQDSQDVLTTLAAIQLPL
VGLLFVLMLLAITQLGSRLQTLKQNIDALSTGDADLTARIQVKGNDELDHIALSVNRFIAYLQQMMVQVTDATDLITREL
AQLDQQTGQARRILGEHAAETDQVVTALTELSSTADSVAQHASDSASFTEAANGQAANSRKVVGSASASVVALIDDVDLA
AAKVLEMQEDAKQIGSVLGVIGGIAAQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAARTQKSTAEVGSMLSRLTQG
VADAVVAMEQTKRSCQAAADTTGQVTGGLDSMADSVVQIHDLSSQIATAAEEQSRVTEEINRNMVSIRDMLNLLVENGRN
TEQSAESLLSSNRQLLALVRRFKV
>Mature_663_residues
GWSLGTIKGRYTAVFVGFMVLVCALTVIGIQIWIKPALQKAGEQNVTLLVSEIATDILDELNGVQSQSRSITQLVAQLPS
EQIDALLPALIDQYGNAMVFGGGIWPLPDQREAGRAKFSTFFHRDAANKLIPNTYWNSAEAPNYFEQPWHKAGQQAPQGM
CVWAAAYKDGASQQPRTNCAMGIYRNGALFGVSTIDVTLGFFNDLVARKEQEIGGQVMIIEADGKILSKNARLNGDVVLG
NLSAHADYPFAGAIASLIGQSRGTGLLRTTFQDQGQEQTLLLQAIEGTPWLLATALPTSTLTQDSQDVLTTLAAIQLPLV
GLLFVLMLLAITQLGSRLQTLKQNIDALSTGDADLTARIQVKGNDELDHIALSVNRFIAYLQQMMVQVTDATDLITRELA
QLDQQTGQARRILGEHAAETDQVVTALTELSSTADSVAQHASDSASFTEAANGQAANSRKVVGSASASVVALIDDVDLAA
AKVLEMQEDAKQIGSVLGVIGGIAAQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAARTQKSTAEVGSMLSRLTQGV
ADAVVAMEQTKRSCQAAADTTGQVTGGLDSMADSVVQIHDLSSQIATAAEEQSRVTEEINRNMVSIRDMLNLLVENGRNT
EQSAESLLSSNRQLLALVRRFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=273, Percent_Identity=31.1355311355311, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI2367378, Length=308, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787690, Length=342, Percent_Identity=26.0233918128655, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1788194, Length=135, Percent_Identity=39.2592592592593, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789453, Length=238, Percent_Identity=33.6134453781513, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 70844; Mature: 70713

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGWSLGTIKGRYTAVFVGFMVLVCALTVIGIQIWIKPALQKAGEQNVTLLVSEIATDILD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ELNGVQSQSRSITQLVAQLPSEQIDALLPALIDQYGNAMVFGGGIWPLPDQREAGRAKFS
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHH
TFFHRDAANKLIPNTYWNSAEAPNYFEQPWHKAGQQAPQGMCVWAAAYKDGASQQPRTNC
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEHHCCCCCCCCCCCH
AMGIYRNGALFGVSTIDVTLGFFNDLVARKEQEIGGQVMIIEADGKILSKNARLNGDVVL
HHHEECCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCCCCCCCEEE
GNLSAHADYPFAGAIASLIGQSRGTGLLRTTFQDQGQEQTLLLQAIEGTPWLLATALPTS
ECCCCCCCCCHHHHHHHHHCCCCCCCCEEECHHHCCCCHHHHHHHHCCCCEEEEECCCCH
TLTQDSQDVLTTLAAIQLPLVGLLFVLMLLAITQLGSRLQTLKQNIDALSTGDADLTARI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
QVKGNDELDHIALSVNRFIAYLQQMMVQVTDATDLITRELAQLDQQTGQARRILGEHAAE
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
TDQVVTALTELSSTADSVAQHASDSASFTEAANGQAANSRKVVGSASASVVALIDDVDLA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCEECCCCCCEEEEECCHHHH
AAKVLEMQEDAKQIGSVLGVIGGIAAQTNLLALNAAIEAARAGEQGRGFAVVADEVRALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHH
ARTQKSTAEVGSMLSRLTQGVADAVVAMEQTKRSCQAAADTTGQVTGGLDSMADSVVQIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
DLSSQIATAAEEQSRVTEEINRNMVSIRDMLNLLVENGRNTEQSAESLLSSNRQLLALVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHH
RFKV
HHCC
>Mature Secondary Structure 
GWSLGTIKGRYTAVFVGFMVLVCALTVIGIQIWIKPALQKAGEQNVTLLVSEIATDILD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ELNGVQSQSRSITQLVAQLPSEQIDALLPALIDQYGNAMVFGGGIWPLPDQREAGRAKFS
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHH
TFFHRDAANKLIPNTYWNSAEAPNYFEQPWHKAGQQAPQGMCVWAAAYKDGASQQPRTNC
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEHHCCCCCCCCCCCH
AMGIYRNGALFGVSTIDVTLGFFNDLVARKEQEIGGQVMIIEADGKILSKNARLNGDVVL
HHHEECCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCCCCCCCEEE
GNLSAHADYPFAGAIASLIGQSRGTGLLRTTFQDQGQEQTLLLQAIEGTPWLLATALPTS
ECCCCCCCCCHHHHHHHHHCCCCCCCCEEECHHHCCCCHHHHHHHHCCCCEEEEECCCCH
TLTQDSQDVLTTLAAIQLPLVGLLFVLMLLAITQLGSRLQTLKQNIDALSTGDADLTARI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
QVKGNDELDHIALSVNRFIAYLQQMMVQVTDATDLITRELAQLDQQTGQARRILGEHAAE
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
TDQVVTALTELSSTADSVAQHASDSASFTEAANGQAANSRKVVGSASASVVALIDDVDLA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCEECCCCCCEEEEECCHHHH
AAKVLEMQEDAKQIGSVLGVIGGIAAQTNLLALNAAIEAARAGEQGRGFAVVADEVRALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHH
ARTQKSTAEVGSMLSRLTQGVADAVVAMEQTKRSCQAAADTTGQVTGGLDSMADSVVQIH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
DLSSQIATAAEEQSRVTEEINRNMVSIRDMLNLLVENGRNTEQSAESLLSSNRQLLALVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHH
RFKV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]