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The map label for this gene is gcp [H]

Identifier: 145300340

GI number: 145300340

Start: 3755540

End: 3756553

Strand: Direct

Name: gcp [H]

Synonym: ASA_3465

Alternate gene names: 145300340

Gene position: 3755540-3756553 (Clockwise)

Preceding gene: 145300334

Following gene: 145300355

Centisome position: 79.86

GC content: 61.34

Gene sequence:

>1014_bases
ATGCGTGTATTGGGCATAGAGACATCCTGTGACGAAACCGGGATCGCGATCTTCGACGATCAAAAAGGGATCCTTTCCCA
TCAGTTGTACAGCCAGGTCAAGCTGCATGCGGACTACGGTGGCGTTGTCCCCGAGCTCGCCAGCCGGGATCACGTTCGCA
AGACGATCCCCTTGATCCAGGCCGCATTGCAAGAGGCGGGACTGGATAAAGATGGCATCGACGGCATCGCGTATACAGCA
GGGCCGGGTCTGGTTGGCGCCATTCTGGTGGGGGCCACCATAGGCCGCTCGCTGGCCATGGCGTGGAACAAACCGGCCAT
CGCCGTACATCATATGGAAGGCCACCTGCTGGCTCCCATGCTGGAAGAGAGAGCGCCCGAGTTCCCCTTCGTGGCACTGC
TGGTCTCCGGTGGTCACTCCATGCTGGTGCGAGTCGACGGGATCGGCAGCTACCAGCTGCTGGGCGAGTCCATCGATGAT
GCCGCCGGCGAGGCATTCGACAAGACTGCCAAGCTGATGGGGCTGGACTACCCGGGTGGCCCACTGCTTTCCAGGTTGGC
AGAAAAGGGCACCACCGGACGTTTCCACTTCCCCCGCCCGATGACTGACCGCCCGGGACTCGACATGAGCTTTTCCGGTC
TCAAGACCTTTGCCGCCAACACCATCGCCGCTAACGGTGATGATGAGCAGACCCGTGCCGATATCGCCCGTGCGTTTGAA
GATGCGGTGGTCGATACCCTGGCTATCAAGTGCCGTCGCGCTCTGAAAGAGACCGGCCTAAAACGGCTGGTGGTGGCCGG
TGGCGTCAGTGCCAACCGTCACCTGCGTGCCCAGCTGGCCGAGCTGATGGAGAGCCTCAAGGGTAAGGTGTTCTATCCGC
GCACCGAATATTGCACCGATAACGGCGCCATGATCGCCTATGCCGGCATGCAGCGCCTGAAGGCAGGGGTGTTCGAGCCG
CTGGCGGTCAAAGCAGTGCCACGCTGGCCACTGGACACTCTGGATCCAGTGTGA

Upstream 100 bases:

>100_bases
TGGACAGGGAATGAAAGTAAACCCGCAGAGATCGCTCTGGTTTAAAAAACCCGCGAAGGTTACCATAGCCGTCTCATTTT
AGCAGTGAAATTTTTTAGCA

Downstream 100 bases:

>100_bases
TCTTGCGGATCCAGTTGTAATAGAAGAAGGGGCCCATGGCCCCTTCTTCATTTCTATCAGCAATATCAGACTGCCTTGGT
ACTAACTAATTGGTACGAAA

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MRVLGIETSCDETGIAIFDDQKGILSHQLYSQVKLHADYGGVVPELASRDHVRKTIPLIQAALQEAGLDKDGIDGIAYTA
GPGLVGAILVGATIGRSLAMAWNKPAIAVHHMEGHLLAPMLEERAPEFPFVALLVSGGHSMLVRVDGIGSYQLLGESIDD
AAGEAFDKTAKLMGLDYPGGPLLSRLAEKGTTGRFHFPRPMTDRPGLDMSFSGLKTFAANTIAANGDDEQTRADIARAFE
DAVVDTLAIKCRRALKETGLKRLVVAGGVSANRHLRAQLAELMESLKGKVFYPRTEYCTDNGAMIAYAGMQRLKAGVFEP
LAVKAVPRWPLDTLDPV

Sequences:

>Translated_337_residues
MRVLGIETSCDETGIAIFDDQKGILSHQLYSQVKLHADYGGVVPELASRDHVRKTIPLIQAALQEAGLDKDGIDGIAYTA
GPGLVGAILVGATIGRSLAMAWNKPAIAVHHMEGHLLAPMLEERAPEFPFVALLVSGGHSMLVRVDGIGSYQLLGESIDD
AAGEAFDKTAKLMGLDYPGGPLLSRLAEKGTTGRFHFPRPMTDRPGLDMSFSGLKTFAANTIAANGDDEQTRADIARAFE
DAVVDTLAIKCRRALKETGLKRLVVAGGVSANRHLRAQLAELMESLKGKVFYPRTEYCTDNGAMIAYAGMQRLKAGVFEP
LAVKAVPRWPLDTLDPV
>Mature_337_residues
MRVLGIETSCDETGIAIFDDQKGILSHQLYSQVKLHADYGGVVPELASRDHVRKTIPLIQAALQEAGLDKDGIDGIAYTA
GPGLVGAILVGATIGRSLAMAWNKPAIAVHHMEGHLLAPMLEERAPEFPFVALLVSGGHSMLVRVDGIGSYQLLGESIDD
AAGEAFDKTAKLMGLDYPGGPLLSRLAEKGTTGRFHFPRPMTDRPGLDMSFSGLKTFAANTIAANGDDEQTRADIARAFE
DAVVDTLAIKCRRALKETGLKRLVVAGGVSANRHLRAQLAELMESLKGKVFYPRTEYCTDNGAMIAYAGMQRLKAGVFEP
LAVKAVPRWPLDTLDPV

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=357, Percent_Identity=34.1736694677871, Blast_Score=185, Evalue=6e-47,
Organism=Homo sapiens, GI8923380, Length=337, Percent_Identity=31.1572700296736, Blast_Score=143, Evalue=2e-34,
Organism=Escherichia coli, GI1789445, Length=334, Percent_Identity=78.7425149700599, Blast_Score=544, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI17557464, Length=327, Percent_Identity=30.8868501529052, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71995670, Length=339, Percent_Identity=30.0884955752212, Blast_Score=126, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320099, Length=368, Percent_Identity=32.0652173913043, Blast_Score=178, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6322891, Length=297, Percent_Identity=27.9461279461279, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI20129063, Length=340, Percent_Identity=34.7058823529412, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI21357207, Length=333, Percent_Identity=30.03003003003, Blast_Score=143, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36147; Mature: 36147

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGIETSCDETGIAIFDDQKGILSHQLYSQVKLHADYGGVVPELASRDHVRKTIPLIQ
CEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
AALQEAGLDKDGIDGIAYTAGPGLVGAILVGATIGRSLAMAWNKPAIAVHHMEGHLLAPM
HHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
LEERAPEFPFVALLVSGGHSMLVRVDGIGSYQLLGESIDDAAGEAFDKTAKLMGLDYPGG
HHHHCCCCCEEEEEEECCCEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
PLLSRLAEKGTTGRFHFPRPMTDRPGLDMSFSGLKTFAANTIAANGDDEQTRADIARAFE
HHHHHHHHCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHEECCCCCHHHHHHHHHHHH
DAVVDTLAIKCRRALKETGLKRLVVAGGVSANRHLRAQLAELMESLKGKVFYPRTEYCTD
HHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCHHHHHHHHHHHHHHCCCEECCCHHCCCC
NGAMIAYAGMQRLKAGVFEPLAVKAVPRWPLDTLDPV
CCCEEEHHHHHHHHHHCCCCHHEEECCCCCCCCCCCC
>Mature Secondary Structure
MRVLGIETSCDETGIAIFDDQKGILSHQLYSQVKLHADYGGVVPELASRDHVRKTIPLIQ
CEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
AALQEAGLDKDGIDGIAYTAGPGLVGAILVGATIGRSLAMAWNKPAIAVHHMEGHLLAPM
HHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
LEERAPEFPFVALLVSGGHSMLVRVDGIGSYQLLGESIDDAAGEAFDKTAKLMGLDYPGG
HHHHCCCCCEEEEEEECCCEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
PLLSRLAEKGTTGRFHFPRPMTDRPGLDMSFSGLKTFAANTIAANGDDEQTRADIARAFE
HHHHHHHHCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHEECCCCCHHHHHHHHHHHH
DAVVDTLAIKCRRALKETGLKRLVVAGGVSANRHLRAQLAELMESLKGKVFYPRTEYCTD
HHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCHHHHHHHHHHHHHHCCCEECCCHHCCCC
NGAMIAYAGMQRLKAGVFEPLAVKAVPRWPLDTLDPV
CCCEEEHHHHHHHHHHCCCCHHEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA