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The map label for this gene is ybbO [H]

Identifier: 145300144

GI number: 145300144

Start: 3513588

End: 3514421

Strand: Direct

Name: ybbO [H]

Synonym: ASA_3247

Alternate gene names: 145300144

Gene position: 3513588-3514421 (Clockwise)

Preceding gene: 145300143

Following gene: 145300146

Centisome position: 74.72

GC content: 62.83

Gene sequence:

>834_bases
ATGGATGATTACCCCTTCGTGCTCATCACCGGCTGTTCCAGTGGCATAGGCCTCGCCGCCGCCAAGGCGCTCGGTGACCA
CGGCTTTACCGTGATCGCCTCCGCTCGCAAGGCCGACGATGTAGCACAGCTGCAACAGCAGGGTTTACTGGCTGTACAAC
TGGATCTGGCCGATACCGCCAGCATTGAGCAGGGTGCTGCCGAGGCACTGGAGCTGGCCGGAGGCCGTCTCTACGGCCTG
TTCAACAACGGTGCCTATGGCCAGCCTGGCGCACTGGAAGACTTGCCCACAGAGGCGCTGCGGGCCCAGTTCGACACCAA
TCTGTTTGGCTGGCATCACCTGATCCGCCAGATACTGCCGACCATGCTGGCAGCCCGGGAGGGGCGCATAGTGCAGAACA
GCTCGGTGCTGGGGCTGGTGGCCATGAAGTATCGCGGCGCCTACAACGCCAGCAAGTTTGCCCTTGAAGGCTATACCGAC
ACCCTGCGCCTCGAACTTGAGGGAAGCGGCGTGCACATCAGCCTGATCGAACCCGGTCCCATCGATACCCGCTTTCGTGC
CAATGCCCACGCCGCCTTCGTGCGCCATATCGATCCGGCCCAGAGTCGTCATCAGGGCGCCTATCGCCAGACCCTGACCC
GGTTGGAAAAAGAGGGGGCCACCAGCGGCTTCACGCTGCCAAGCGATGCCTGCATTCCGCCACTGCTCCATGCACTGCAG
AGCAAGCGCCCCAAGCATCGCTACCCTGTCACCTTCCCGACCCGGTTGTTTGCGATACTGCGCCGCCTGCTGCCAAGCAG
CTGGCTTGACCGGATCCTCTCCAAGTCGGCCTGA

Upstream 100 bases:

>100_bases
CAGGCGGTGCAACCTCAGCAAACCGGGCCCCTTGGCCCGGTTTTCTTTTTGGCCGCACTCAGGCTACCATGCCCACCTTG
GCCACACTCAGGCCGCCACC

Downstream 100 bases:

>100_bases
TCCTTGATTCACACAGGGTGAGTGGCACCGCCTGCTCGCCCTGCGGTTGATGATGTGACCCCCGTCTGCCCCTTGCCCGC
CATCTGTCCCGCAGCCAGGA

Product: short-chain dehydrogenase/reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MDDYPFVLITGCSSGIGLAAAKALGDHGFTVIASARKADDVAQLQQQGLLAVQLDLADTASIEQGAAEALELAGGRLYGL
FNNGAYGQPGALEDLPTEALRAQFDTNLFGWHHLIRQILPTMLAAREGRIVQNSSVLGLVAMKYRGAYNASKFALEGYTD
TLRLELEGSGVHISLIEPGPIDTRFRANAHAAFVRHIDPAQSRHQGAYRQTLTRLEKEGATSGFTLPSDACIPPLLHALQ
SKRPKHRYPVTFPTRLFAILRRLLPSSWLDRILSKSA

Sequences:

>Translated_277_residues
MDDYPFVLITGCSSGIGLAAAKALGDHGFTVIASARKADDVAQLQQQGLLAVQLDLADTASIEQGAAEALELAGGRLYGL
FNNGAYGQPGALEDLPTEALRAQFDTNLFGWHHLIRQILPTMLAAREGRIVQNSSVLGLVAMKYRGAYNASKFALEGYTD
TLRLELEGSGVHISLIEPGPIDTRFRANAHAAFVRHIDPAQSRHQGAYRQTLTRLEKEGATSGFTLPSDACIPPLLHALQ
SKRPKHRYPVTFPTRLFAILRRLLPSSWLDRILSKSA
>Mature_277_residues
MDDYPFVLITGCSSGIGLAAAKALGDHGFTVIASARKADDVAQLQQQGLLAVQLDLADTASIEQGAAEALELAGGRLYGL
FNNGAYGQPGALEDLPTEALRAQFDTNLFGWHHLIRQILPTMLAAREGRIVQNSSVLGLVAMKYRGAYNASKFALEGYTD
TLRLELEGSGVHISLIEPGPIDTRFRANAHAAFVRHIDPAQSRHQGAYRQTLTRLEKEGATSGFTLPSDACIPPLLHALQ
SKRPKHRYPVTFPTRLFAILRRLLPSSWLDRILSKSA

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=189, Percent_Identity=39.1534391534392, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI19743808, Length=289, Percent_Identity=33.9100346020761, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI40548397, Length=284, Percent_Identity=30.9859154929577, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI214010158, Length=284, Percent_Identity=30.9859154929577, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI214010156, Length=284, Percent_Identity=30.9859154929577, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI22758144, Length=284, Percent_Identity=30.9859154929577, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI150247226, Length=286, Percent_Identity=30.4195804195804, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI223718074, Length=191, Percent_Identity=37.17277486911, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI7706318, Length=199, Percent_Identity=32.6633165829146, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI22507405, Length=280, Percent_Identity=29.6428571428571, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=31.8181818181818, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI50726952, Length=287, Percent_Identity=28.9198606271777, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI44680136, Length=183, Percent_Identity=32.2404371584699, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI44680133, Length=183, Percent_Identity=32.2404371584699, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI17738292, Length=183, Percent_Identity=32.2404371584699, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI119392083, Length=210, Percent_Identity=31.4285714285714, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=31.0880829015544, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI5031737, Length=189, Percent_Identity=31.7460317460317, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI157739938, Length=222, Percent_Identity=26.5765765765766, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4504503, Length=180, Percent_Identity=29.4444444444444, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4503817, Length=188, Percent_Identity=29.7872340425532, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI32483357, Length=186, Percent_Identity=30.6451612903226, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1786701, Length=267, Percent_Identity=43.4456928838951, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI87082100, Length=183, Percent_Identity=32.2404371584699, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1787335, Length=185, Percent_Identity=29.1891891891892, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787820, Length=198, Percent_Identity=26.7676767676768, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786812, Length=181, Percent_Identity=32.0441988950276, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=281, Percent_Identity=27.4021352313167, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17557780, Length=288, Percent_Identity=26.7361111111111, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71997402, Length=270, Percent_Identity=28.8888888888889, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI193210355, Length=278, Percent_Identity=29.136690647482, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17570069, Length=190, Percent_Identity=32.6315789473684, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32563809, Length=293, Percent_Identity=25.938566552901, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=291, Percent_Identity=25.4295532646048, Blast_Score=71, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=31.0880829015544, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322067, Length=172, Percent_Identity=30.2325581395349, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320089, Length=186, Percent_Identity=27.9569892473118, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=31.4432989690722, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24580925, Length=193, Percent_Identity=31.0880829015544, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24651139, Length=214, Percent_Identity=31.7757009345794, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24644339, Length=190, Percent_Identity=31.0526315789474, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28571526, Length=244, Percent_Identity=27.8688524590164, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21357041, Length=243, Percent_Identity=25.5144032921811, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24643142, Length=200, Percent_Identity=30, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI23397609, Length=187, Percent_Identity=31.5508021390374, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI19922066, Length=271, Percent_Identity=26.9372693726937, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641232, Length=195, Percent_Identity=28.7179487179487, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21356301, Length=188, Percent_Identity=28.1914893617021, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30098; Mature: 30098

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDYPFVLITGCSSGIGLAAAKALGDHGFTVIASARKADDVAQLQQQGLLAVQLDLADTA
CCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCEEEEEECCCCC
SIEQGAAEALELAGGRLYGLFNNGAYGQPGALEDLPTEALRAQFDTNLFGWHHLIRQILP
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHCCHHHHHHHHCCCHHHHHHHHHHHHH
TMLAAREGRIVQNSSVLGLVAMKYRGAYNASKFALEGYTDTLRLELEGSGVHISLIEPGP
HHHHHHCCCEEECCCCCEEHHHHHCCCCCCCCEEECCCCEEEEEEEECCCEEEEEECCCC
IDTRFRANAHAAFVRHIDPAQSRHQGAYRQTLTRLEKEGATSGFTLPSDACIPPLLHALQ
CCCCCCCCHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
SKRPKHRYPVTFPTRLFAILRRLLPSSWLDRILSKSA
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MDDYPFVLITGCSSGIGLAAAKALGDHGFTVIASARKADDVAQLQQQGLLAVQLDLADTA
CCCCCEEEEECCCCCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCEEEEEECCCCC
SIEQGAAEALELAGGRLYGLFNNGAYGQPGALEDLPTEALRAQFDTNLFGWHHLIRQILP
HHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHCCHHHHHHHHCCCHHHHHHHHHHHHH
TMLAAREGRIVQNSSVLGLVAMKYRGAYNASKFALEGYTDTLRLELEGSGVHISLIEPGP
HHHHHHCCCEEECCCCCEEHHHHHCCCCCCCCEEECCCCEEEEEEEECCCEEEEEECCCC
IDTRFRANAHAAFVRHIDPAQSRHQGAYRQTLTRLEKEGATSGFTLPSDACIPPLLHALQ
CCCCCCCCHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
SKRPKHRYPVTFPTRLFAILRRLLPSSWLDRILSKSA
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]