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The map label for this gene is suhB [H]

Identifier: 145299578

GI number: 145299578

Start: 2833755

End: 2834558

Strand: Direct

Name: suhB [H]

Synonym: ASA_2649

Alternate gene names: 145299578

Gene position: 2833755-2834558 (Clockwise)

Preceding gene: 145299571

Following gene: 145299580

Centisome position: 60.26

GC content: 57.34

Gene sequence:

>804_bases
ATGCATCCGATGCTGAATATCGCCGTGCGCGCTGCGCGCAACGCCGGTCAAGTAGTAGTAAAAGCCTTTTCCCAGCCCGA
AAACATCGAGGCCATCCAGAAAGGCAGCAATGACTTCGTGACCAACGTTGACCGTGACGCCGAAGCGGCCATCATTCACA
CCATCAAAAAATCTTACCCGGAACACAGCATCATTGCTGAAGAGTCTGGTGAGATTGCCGGTACCAATCCGGACTACCAA
TGGATCATTGACCCACTGGATGGCACGACCAACCTCGTCAAGGGCATTCCGCACTTTGCCGTCTCCATCGCTCTGCGCGT
CAAGGGCAAGACAGAACAAGCCGTCGTCTACGATCCCATCCGTGACGAGCTGTTTACCGCGACCCGTGGTAACGGCGCTC
AGCTGAACGGCTACCGCATCCGTGTCGGCAAGGCCAAAGAGCTGGCTGGCACCGTTCTGGCCACCGGTTTCCCATTCAAG
CAGAAGCATCATATCGAGCCCTACCTGAAGATGTTCCAGAGCATGTTCATCGAATGTGCCGACATCCGTCGTTCCGGCTC
TGCCGCACTGGATCTGGCCTATGTGGCCGCCGGTCGCGTCGACGGTTTCTGGGAGATCGGCCTCAAGCCCTGGGATACCG
CAGCCGGTGAACTGCTGGCCAAAGAGTCCGGCGCCATCGTCACCGACTTCGTGGGTGGTCACAACTACGAAAACTCCGGC
AACATAGTGGTTGCCAACCCGCGCGTCCTGAAAGAGATGCTCGGCAAGATCCGTGAGAACCTGCCGGAATCTCTGGCCAA
GTAA

Upstream 100 bases:

>100_bases
AAGGTCGGGGAGAAGGCGTATAACGGTTGCCATTATCGAAAAGACTGGTATCATACCGCGTCCTTTTATCCCCCGTTCTT
TAACATCCAGTGGTGAACCT

Downstream 100 bases:

>100_bases
GTCGTTACCCACAGCGCACACACATTGAACCCGGTCCAGGCCGGGTTTTTTTATGTCTATTGCCAAGCAATTTATCTGCA
AAGCCGCAAAACAATCCTGC

Product: inositol-1-monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MHPMLNIAVRAARNAGQVVVKAFSQPENIEAIQKGSNDFVTNVDRDAEAAIIHTIKKSYPEHSIIAEESGEIAGTNPDYQ
WIIDPLDGTTNLVKGIPHFAVSIALRVKGKTEQAVVYDPIRDELFTATRGNGAQLNGYRIRVGKAKELAGTVLATGFPFK
QKHHIEPYLKMFQSMFIECADIRRSGSAALDLAYVAAGRVDGFWEIGLKPWDTAAGELLAKESGAIVTDFVGGHNYENSG
NIVVANPRVLKEMLGKIRENLPESLAK

Sequences:

>Translated_267_residues
MHPMLNIAVRAARNAGQVVVKAFSQPENIEAIQKGSNDFVTNVDRDAEAAIIHTIKKSYPEHSIIAEESGEIAGTNPDYQ
WIIDPLDGTTNLVKGIPHFAVSIALRVKGKTEQAVVYDPIRDELFTATRGNGAQLNGYRIRVGKAKELAGTVLATGFPFK
QKHHIEPYLKMFQSMFIECADIRRSGSAALDLAYVAAGRVDGFWEIGLKPWDTAAGELLAKESGAIVTDFVGGHNYENSG
NIVVANPRVLKEMLGKIRENLPESLAK
>Mature_267_residues
MHPMLNIAVRAARNAGQVVVKAFSQPENIEAIQKGSNDFVTNVDRDAEAAIIHTIKKSYPEHSIIAEESGEIAGTNPDYQ
WIIDPLDGTTNLVKGIPHFAVSIALRVKGKTEQAVVYDPIRDELFTATRGNGAQLNGYRIRVGKAKELAGTVLATGFPFK
QKHHIEPYLKMFQSMFIECADIRRSGSAALDLAYVAAGRVDGFWEIGLKPWDTAAGELLAKESGAIVTDFVGGHNYENSG
NIVVANPRVLKEMLGKIRENLPESLAK

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=263, Percent_Identity=34.2205323193916, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI221625487, Length=263, Percent_Identity=34.2205323193916, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI7657236, Length=259, Percent_Identity=31.6602316602317, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI221625507, Length=143, Percent_Identity=40.5594405594406, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI1788882, Length=267, Percent_Identity=67.0411985018727, Blast_Score=390, Evalue=1e-110,
Organism=Escherichia coli, GI1790659, Length=131, Percent_Identity=29.7709923664122, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193202572, Length=239, Percent_Identity=34.7280334728033, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI193202570, Length=239, Percent_Identity=33.0543933054393, Blast_Score=130, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6320493, Length=213, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321836, Length=227, Percent_Identity=30.8370044052863, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21357329, Length=234, Percent_Identity=34.1880341880342, Blast_Score=148, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24664926, Length=244, Percent_Identity=31.9672131147541, Blast_Score=134, Evalue=7e-32,
Organism=Drosophila melanogaster, GI21357303, Length=233, Percent_Identity=34.3347639484979, Blast_Score=128, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24664922, Length=260, Percent_Identity=28.8461538461538, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21357957, Length=242, Percent_Identity=30.9917355371901, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24664918, Length=231, Percent_Identity=33.7662337662338, Blast_Score=113, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29140; Mature: 29140

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPMLNIAVRAARNAGQVVVKAFSQPENIEAIQKGSNDFVTNVDRDAEAAIIHTIKKSYP
CCCHHHHHHHHCCCCCHHHHEECCCCCCHHHHHCCCCCCEECCCCCHHHHHHHHHHHCCC
EHSIIAEESGEIAGTNPDYQWIIDPLDGTTNLVKGIPHFAVSIALRVKGKTEQAVVYDPI
CCCEEECCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEEEEEEECCCCCCEEEECCH
RDELFTATRGNGAQLNGYRIRVGKAKELAGTVLATGFPFKQKHHIEPYLKMFQSMFIECA
HHHHHHCCCCCCCEECCEEEEECCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
DIRRSGSAALDLAYVAAGRVDGFWEIGLKPWDTAAGELLAKESGAIVTDFVGGHNYENSG
HHHCCCCCCEEHHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCC
NIVVANPRVLKEMLGKIRENLPESLAK
CEEEECHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHPMLNIAVRAARNAGQVVVKAFSQPENIEAIQKGSNDFVTNVDRDAEAAIIHTIKKSYP
CCCHHHHHHHHCCCCCHHHHEECCCCCCHHHHHCCCCCCEECCCCCHHHHHHHHHHHCCC
EHSIIAEESGEIAGTNPDYQWIIDPLDGTTNLVKGIPHFAVSIALRVKGKTEQAVVYDPI
CCCEEECCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEEEEEEECCCCCCEEEECCH
RDELFTATRGNGAQLNGYRIRVGKAKELAGTVLATGFPFKQKHHIEPYLKMFQSMFIECA
HHHHHHCCCCCCCEECCEEEEECCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHH
DIRRSGSAALDLAYVAAGRVDGFWEIGLKPWDTAAGELLAKESGAIVTDFVGGHNYENSG
HHHCCCCCCEEHHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCC
NIVVANPRVLKEMLGKIRENLPESLAK
CEEEECHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]