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The map label for this gene is nagD [H]

Identifier: 145299445

GI number: 145299445

Start: 2675195

End: 2675944

Strand: Direct

Name: nagD [H]

Synonym: ASA_2507

Alternate gene names: 145299445

Gene position: 2675195-2675944 (Clockwise)

Preceding gene: 145299443

Following gene: 145299446

Centisome position: 56.89

GC content: 59.47

Gene sequence:

>750_bases
ATGAAAAAAAGCGTCATCTGTGACATCGACGGCGTCATTCTGCACAACAACGATCTCATCCCCGGTGCCGACCGCTTCGT
CCATCGCCTGCTGGAACAGGGCACCAAGCTGTTGTTCCTCACCAACTACCCGGCCCAGACCCAGAAAGATCTGCAAAACC
GCTTCCGCTCCGCCGGGATCGAAGTGCCGGAGGAGTGCTTCTACACCTCCGCCATGGGCACAGCCGATTTTCTCAAACGC
CAGGATGGCAAGAAGGCCTATGTGATTGGTGAGGGGGCCCTGACCCACGAGCTCTACAAGGCCGGTTTCACCATCACCGA
CATAGACCCCGACTTCGTGGTCGTGGGCGAGACCCGCAACTACAACTGGACCATGATGCAGCTGGGGGCCAAGTTTGTGG
ATCAGGGGGCCCGCTTCATCGCCACCAACCCCGATACCCATGGCCCCATGATGCATCCGGCCTGCGGCGCCCTCTGCGCC
CCCATAGAGCGGATGACGGGCAAGAAGCCGTTTTATGTGGGCAAGCCGAGCGCCTGGATCATTCGCGCGGCATTGAACCG
GATGGAGGCCCACTCCGACGACACCATCATCATCGGCGACAACCTGCACACCGATATTCTGGCGGGCTTCCAGGCCGGTC
TTGAAACCGTGCTGGTGCTGTCAGGGGTGAGCAATGTCGCGGATATCGATCGCATGCCGTTTCGCCCGAACCACATCTTC
GACTCAGTCGTGGATATCGATATCGTCTGA

Upstream 100 bases:

>100_bases
GACTTATAATGGCGTCACAAAAACAACATAACTGATTGAAGATATTAAGAGTTGGCGTCCGCCCCGCGTTCACTCTTGTG
CCCTATACAAAGGAGTTCCC

Downstream 100 bases:

>100_bases
TGTGATCACAGGAGTCATCCATGGAACCGCTCTTCATTGCCGTCGCCTTCGCCTGCGGCATGCTGGTCAACCTGGTGGGG
CTGCCTCCCCTGATCGGTTT

Product: UMP phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKKSVICDIDGVILHNNDLIPGADRFVHRLLEQGTKLLFLTNYPAQTQKDLQNRFRSAGIEVPEECFYTSAMGTADFLKR
QDGKKAYVIGEGALTHELYKAGFTITDIDPDFVVVGETRNYNWTMMQLGAKFVDQGARFIATNPDTHGPMMHPACGALCA
PIERMTGKKPFYVGKPSAWIIRAALNRMEAHSDDTIIIGDNLHTDILAGFQAGLETVLVLSGVSNVADIDRMPFRPNHIF
DSVVDIDIV

Sequences:

>Translated_249_residues
MKKSVICDIDGVILHNNDLIPGADRFVHRLLEQGTKLLFLTNYPAQTQKDLQNRFRSAGIEVPEECFYTSAMGTADFLKR
QDGKKAYVIGEGALTHELYKAGFTITDIDPDFVVVGETRNYNWTMMQLGAKFVDQGARFIATNPDTHGPMMHPACGALCA
PIERMTGKKPFYVGKPSAWIIRAALNRMEAHSDDTIIIGDNLHTDILAGFQAGLETVLVLSGVSNVADIDRMPFRPNHIF
DSVVDIDIV
>Mature_249_residues
MKKSVICDIDGVILHNNDLIPGADRFVHRLLEQGTKLLFLTNYPAQTQKDLQNRFRSAGIEVPEECFYTSAMGTADFLKR
QDGKKAYVIGEGALTHELYKAGFTITDIDPDFVVVGETRNYNWTMMQLGAKFVDQGARFIATNPDTHGPMMHPACGALCA
PIERMTGKKPFYVGKPSAWIIRAALNRMEAHSDDTIIIGDNLHTDILAGFQAGLETVLVLSGVSNVADIDRMPFRPNHIF
DSVVDIDIV

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI10092677, Length=272, Percent_Identity=27.2058823529412, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI108796653, Length=291, Percent_Identity=25.085910652921, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI14149777, Length=252, Percent_Identity=23.4126984126984, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1786890, Length=247, Percent_Identity=69.2307692307692, Blast_Score=380, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17562458, Length=276, Percent_Identity=25.7246376811594, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17558880, Length=260, Percent_Identity=25.7692307692308, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560956, Length=260, Percent_Identity=25.7692307692308, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562356, Length=247, Percent_Identity=25.5060728744939, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71984613, Length=266, Percent_Identity=25.5639097744361, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193210059, Length=260, Percent_Identity=25.3846153846154, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319965, Length=235, Percent_Identity=24.6808510638298, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24666141, Length=254, Percent_Identity=28.740157480315, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24656326, Length=255, Percent_Identity=25.8823529411765, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI22026920, Length=241, Percent_Identity=26.5560165975104, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24656330, Length=252, Percent_Identity=26.5873015873016, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 27586; Mature: 27586

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSVICDIDGVILHNNDLIPGADRFVHRLLEQGTKLLFLTNYPAQTQKDLQNRFRSAGI
CCCCEEEECCCEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCC
EVPEECFYTSAMGTADFLKRQDGKKAYVIGEGALTHELYKAGFTITDIDPDFVVVGETRN
CCCHHHHHHHHCCHHHHHHCCCCCEEEEEECCHHHHHHHHCCCEEEECCCCEEEEECCCC
YNWTMMQLGAKFVDQGARFIATNPDTHGPMMHPACGALCAPIERMTGKKPFYVGKPSAWI
CCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCHHH
IRAALNRMEAHSDDTIIIGDNLHTDILAGFQAGLETVLVLSGVSNVADIDRMPFRPNHIF
HHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHH
DSVVDIDIV
HHHEEEECC
>Mature Secondary Structure
MKKSVICDIDGVILHNNDLIPGADRFVHRLLEQGTKLLFLTNYPAQTQKDLQNRFRSAGI
CCCCEEEECCCEEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCC
EVPEECFYTSAMGTADFLKRQDGKKAYVIGEGALTHELYKAGFTITDIDPDFVVVGETRN
CCCHHHHHHHHCCHHHHHHCCCCCEEEEEECCHHHHHHHHCCCEEEECCCCEEEEECCCC
YNWTMMQLGAKFVDQGARFIATNPDTHGPMMHPACGALCAPIERMTGKKPFYVGKPSAWI
CCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCHHH
IRAALNRMEAHSDDTIIIGDNLHTDILAGFQAGLETVLVLSGVSNVADIDRMPFRPNHIF
HHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHH
DSVVDIDIV
HHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]