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The map label for this gene is aat [H]

Identifier: 145299393

GI number: 145299393

Start: 2607340

End: 2608077

Strand: Direct

Name: aat [H]

Synonym: ASA_2443

Alternate gene names: 145299393

Gene position: 2607340-2608077 (Clockwise)

Preceding gene: 145299391

Following gene: 145299394

Centisome position: 55.45

GC content: 59.08

Gene sequence:

>738_bases
ATGGCCTTCATCTGTGAACCTCTTCGCCTTATGTCTCGCTATCTTACCCAATTGGATGATGCGCTGTGCTGGTTTCCCGA
CCCCGAGCACGCACTGGATGAACCCAACGGCCTGCTGGCGATCGGCGGGGATCTCTCCCCTGAACGATTGCTGGCAGCTT
ACCACAAGGGGATCTTCCCGTGGAATGAGCCCCACCAGCCGTTGCTGTGGTGGTCGCCGGATCCCAGAGGGGTCATCATC
CCCGAACAGCTGCACATAGGTCGCAGCCTGCGCAAATTTATCCGCCGCACCTCATTCGATATTTCCATCAATCGCGCCTT
TAATGAGGTAATAGCGGCCTGCGCCGCCCCCCGTCGCAGCGCCAGTGGAACCTGGATAAGCACGCCCATGATCGACGCCT
ATCGACAACTTCATCGCCTTGGCCATGCCCACTCCGTCGAGATCTGGCAGCATGGCCAGTTGCAAGCTGGCCTCTATGGC
CTCTCCCTCGGCCGCCTCTTCTGCGGTGAGTCCATGTTCAGCCGCATCGACAACGGCGCCAAGCTAGCCATGGTGGCGCT
CTGTCACCACTTCGCCAGCCACGGTGGTGCACTGATCGATTGCCAGATGCAGAATGATTTTCTGGCTACCATGGGGATCC
AGGAGTGGCCAAGAGAGACGTTTTTGACGGCGCTGACCAAACTGAGCCGGCAGCCGTTGGCAGATAACTGCTGGCAAGCG
GGGAGCATCAGCCTATGA

Upstream 100 bases:

>100_bases
AAACACCACCTGATTGACGGGCCGCGCCGTGTTGCGCTCGTAAACCTGGGCCCCGGCAGGCGCAGTGACAAAGCAGAGCA
AGCTGGATACTATCAGGATA

Downstream 100 bases:

>100_bases
CAGAAGAAGTGATCCTAAAAGTAGGTCTGACCCCCAAGCATCAATGCAGCTATCTGGGCCATGAACAGGAGCAACTGCTG
GTATTGATGGACCACAACCT

Product: leucyl/phenylalanyl-tRNA--protein transferase

Products: NA

Alternate protein names: L/F-transferase; Leucyltransferase; Phenyalanyltransferase [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MAFICEPLRLMSRYLTQLDDALCWFPDPEHALDEPNGLLAIGGDLSPERLLAAYHKGIFPWNEPHQPLLWWSPDPRGVII
PEQLHIGRSLRKFIRRTSFDISINRAFNEVIAACAAPRRSASGTWISTPMIDAYRQLHRLGHAHSVEIWQHGQLQAGLYG
LSLGRLFCGESMFSRIDNGAKLAMVALCHHFASHGGALIDCQMQNDFLATMGIQEWPRETFLTALTKLSRQPLADNCWQA
GSISL

Sequences:

>Translated_245_residues
MAFICEPLRLMSRYLTQLDDALCWFPDPEHALDEPNGLLAIGGDLSPERLLAAYHKGIFPWNEPHQPLLWWSPDPRGVII
PEQLHIGRSLRKFIRRTSFDISINRAFNEVIAACAAPRRSASGTWISTPMIDAYRQLHRLGHAHSVEIWQHGQLQAGLYG
LSLGRLFCGESMFSRIDNGAKLAMVALCHHFASHGGALIDCQMQNDFLATMGIQEWPRETFLTALTKLSRQPLADNCWQA
GSISL
>Mature_244_residues
AFICEPLRLMSRYLTQLDDALCWFPDPEHALDEPNGLLAIGGDLSPERLLAAYHKGIFPWNEPHQPLLWWSPDPRGVIIP
EQLHIGRSLRKFIRRTSFDISINRAFNEVIAACAAPRRSASGTWISTPMIDAYRQLHRLGHAHSVEIWQHGQLQAGLYGL
SLGRLFCGESMFSRIDNGAKLAMVALCHHFASHGGALIDCQMQNDFLATMGIQEWPRETFLTALTKLSRQPLADNCWQAG
SISL

Specific function: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine [H]

COG id: COG2360

COG function: function code O; Leu/Phe-tRNA-protein transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L/F-transferase family [H]

Homologues:

Organism=Escherichia coli, GI1787111, Length=224, Percent_Identity=51.7857142857143, Blast_Score=251, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR004616 [H]

Pfam domain/function: PF03588 Leu_Phe_trans [H]

EC number: =2.3.2.6 [H]

Molecular weight: Translated: 27541; Mature: 27410

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFICEPLRLMSRYLTQLDDALCWFPDPEHALDEPNGLLAIGGDLSPERLLAAYHKGIFP
CCCCCHHHHHHHHHHHHHHHCEECCCCCHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCC
WNEPHQPLLWWSPDPRGVIIPEQLHIGRSLRKFIRRTSFDISINRAFNEVIAACAAPRRS
CCCCCCCEEEECCCCCCEECCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCC
ASGTWISTPMIDAYRQLHRLGHAHSVEIWQHGQLQAGLYGLSLGRLFCGESMFSRIDNGA
CCCCEECCHHHHHHHHHHHHCCCCEEEHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
KLAMVALCHHFASHGGALIDCQMQNDFLATMGIQEWPRETFLTALTKLSRQPLADNCWQA
HHHHHHHHHHHHHCCCEEEEEEECCCHHHHCCHHHCCHHHHHHHHHHHHCCCCHHHCCCC
GSISL
CCCCC
>Mature Secondary Structure 
AFICEPLRLMSRYLTQLDDALCWFPDPEHALDEPNGLLAIGGDLSPERLLAAYHKGIFP
CCCCHHHHHHHHHHHHHHHCEECCCCCHHHCCCCCCEEEECCCCCHHHHHHHHHHCCCC
WNEPHQPLLWWSPDPRGVIIPEQLHIGRSLRKFIRRTSFDISINRAFNEVIAACAAPRRS
CCCCCCCEEEECCCCCCEECCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCC
ASGTWISTPMIDAYRQLHRLGHAHSVEIWQHGQLQAGLYGLSLGRLFCGESMFSRIDNGA
CCCCEECCHHHHHHHHHHHHCCCCEEEHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
KLAMVALCHHFASHGGALIDCQMQNDFLATMGIQEWPRETFLTALTKLSRQPLADNCWQA
HHHHHHHHHHHHHCCCEEEEEEECCCHHHHCCHHHCCHHHHHHHHHHHHCCCCHHHCCCC
GSISL
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA