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The map label for this gene is trxB [H]

Identifier: 145299390

GI number: 145299390

Start: 2604522

End: 2605472

Strand: Direct

Name: trxB [H]

Synonym: ASA_2440

Alternate gene names: 145299390

Gene position: 2604522-2605472 (Clockwise)

Preceding gene: 145299382

Following gene: 145299391

Centisome position: 55.39

GC content: 60.57

Gene sequence:

>951_bases
ATGAGCCAAGTCACTCACAGCAAACTGCTGATCCTGGGGTCAGGCCCGGCCGGTTACACCGCCGCCGTCTACGCAGCCCG
CGCCAACCTGAATCCTCTGCTCATCACAGGTATGCAGCAAGGTGGTCAGCTGACCACCACCACAGAGGTGGAAAACTGGC
CCGGTGATTCCGAAGGTCTGACCGGTCCAGCCCTGATGGAGCGCATGAAGGCCCATGCGGAGAAGTTCGATACCCGCATC
CTGTTTGATCACATCAATGAAGTGGAGCTGACCCAGCGTCCGTTCCGCCTCAAGGGCGACAGCGCCGAATACACCTGCGA
TGCGCTGATCATCGCCACCGGCGCCTCCGCCAAATATTTGGGACTGCCTTCCGAAGAGGCCTTCAAGGGACGCGGCGTCT
CCGCCTGCGCTACCTGTGACGGCTTCTTCTATCGCAACCAGGAAGTGGCGGTGATCGGCGGCGGCAATACCGCAGTGGAA
GAAGCACTCTATCTTGCCAACATCGCCAAGAAGGTGCACCTCATTCACCGCCGCGATGAGTTTCGCGCCGAGAAGATCCT
GATCAAGCTTCTGCACGACAAGGTAGCGAGCGGCAACATAGTGCTGCACACCCACCAGACCCTGGACGAAGTGCTGGGGG
ATCAGATGGGCGTGACCGGTGTGCGCCTGCGCAGCACGCAGGATGACACCACCACGGATCTGCCGCTGATGGGCGTATTC
ATTGCTATCGGCCACCAGCCGAATACCCAGATCTTCGAGGGCCAGCTGGCGATGCAAAACGGCTACCTGATCGTGCGTGG
CGGACTGGACGGCTTTGCCACCCAGACCAGTATTGAAGGGGTATTTGCCGCCGGCGACGTGGCCGATCACAACTACCGTC
AGGCCATCACGTCTGCCGGCACCGGCTGCATGGCCGCTCTCGATGCCGAGCGATATCTGGACGCGCAATAA

Upstream 100 bases:

>100_bases
GCACCTATGGTCGATTGGCACAATCGACTCACTGACCTTTGACCCCATATCACGAATTACCTACAATCGCGCAAACTCAT
CACGTCTCGGAAATCACATC

Downstream 100 bases:

>100_bases
GCGCAAGGGATATAAAAGGCATGCCGTGAGGCATGCCTTTTTACGTTAAGGAGCCGGATGAAACAGAAAATATTGATTGT
CGAAGATAGCATGACGATCC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSQVTHSKLLILGSGPAGYTAAVYAARANLNPLLITGMQQGGQLTTTTEVENWPGDSEGLTGPALMERMKAHAEKFDTRI
LFDHINEVELTQRPFRLKGDSAEYTCDALIIATGASAKYLGLPSEEAFKGRGVSACATCDGFFYRNQEVAVIGGGNTAVE
EALYLANIAKKVHLIHRRDEFRAEKILIKLLHDKVASGNIVLHTHQTLDEVLGDQMGVTGVRLRSTQDDTTTDLPLMGVF
IAIGHQPNTQIFEGQLAMQNGYLIVRGGLDGFATQTSIEGVFAAGDVADHNYRQAITSAGTGCMAALDAERYLDAQ

Sequences:

>Translated_316_residues
MSQVTHSKLLILGSGPAGYTAAVYAARANLNPLLITGMQQGGQLTTTTEVENWPGDSEGLTGPALMERMKAHAEKFDTRI
LFDHINEVELTQRPFRLKGDSAEYTCDALIIATGASAKYLGLPSEEAFKGRGVSACATCDGFFYRNQEVAVIGGGNTAVE
EALYLANIAKKVHLIHRRDEFRAEKILIKLLHDKVASGNIVLHTHQTLDEVLGDQMGVTGVRLRSTQDDTTTDLPLMGVF
IAIGHQPNTQIFEGQLAMQNGYLIVRGGLDGFATQTSIEGVFAAGDVADHNYRQAITSAGTGCMAALDAERYLDAQ
>Mature_315_residues
SQVTHSKLLILGSGPAGYTAAVYAARANLNPLLITGMQQGGQLTTTTEVENWPGDSEGLTGPALMERMKAHAEKFDTRIL
FDHINEVELTQRPFRLKGDSAEYTCDALIIATGASAKYLGLPSEEAFKGRGVSACATCDGFFYRNQEVAVIGGGNTAVEE
ALYLANIAKKVHLIHRRDEFRAEKILIKLLHDKVASGNIVLHTHQTLDEVLGDQMGVTGVRLRSTQDDTTTDLPLMGVFI
AIGHQPNTQIFEGQLAMQNGYLIVRGGLDGFATQTSIEGVFAAGDVADHNYRQAITSAGTGCMAALDAERYLDAQ

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=78.7301587301587, Blast_Score=513, Evalue=1e-147,
Organism=Escherichia coli, GI87081763, Length=314, Percent_Identity=33.1210191082803, Blast_Score=133, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6321898, Length=328, Percent_Identity=45.7317073170732, Blast_Score=281, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6320560, Length=324, Percent_Identity=46.2962962962963, Blast_Score=276, Evalue=3e-75,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34043; Mature: 33912

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVTHSKLLILGSGPAGYTAAVYAARANLNPLLITGMQQGGQLTTTTEVENWPGDSEGL
CCCCCCEEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCC
TGPALMERMKAHAEKFDTRILFDHINEVELTQRPFRLKGDSAEYTCDALIIATGASAKYL
CCHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCEEECCCCCCEEEEEEEEEECCCEEEE
GLPSEEAFKGRGVSACATCDGFFYRNQEVAVIGGGNTAVEEALYLANIAKKVHLIHRRDE
CCCCHHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
FRAEKILIKLLHDKVASGNIVLHTHQTLDEVLGDQMGVTGVRLRSTQDDTTTDLPLMGVF
HHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHEEEE
IAIGHQPNTQIFEGQLAMQNGYLIVRGGLDGFATQTSIEGVFAAGDVADHNYRQAITSAG
EEECCCCCCEEEECEEEEECCEEEEEECCCCCCCHHCCCEEEEECCCCCCHHHHHHHHCC
TGCMAALDAERYLDAQ
CCCEEEECHHHHCCCC
>Mature Secondary Structure 
SQVTHSKLLILGSGPAGYTAAVYAARANLNPLLITGMQQGGQLTTTTEVENWPGDSEGL
CCCCCEEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCC
TGPALMERMKAHAEKFDTRILFDHINEVELTQRPFRLKGDSAEYTCDALIIATGASAKYL
CCHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCEEECCCCCCEEEEEEEEEECCCEEEE
GLPSEEAFKGRGVSACATCDGFFYRNQEVAVIGGGNTAVEEALYLANIAKKVHLIHRRDE
CCCCHHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
FRAEKILIKLLHDKVASGNIVLHTHQTLDEVLGDQMGVTGVRLRSTQDDTTTDLPLMGVF
HHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHEEEE
IAIGHQPNTQIFEGQLAMQNGYLIVRGGLDGFATQTSIEGVFAAGDVADHNYRQAITSAG
EEECCCCCCEEEECEEEEECCEEEEEECCCCCCCHHCCCEEEEECCCCCCHHHHHHHHCC
TGCMAALDAERYLDAQ
CCCEEEECHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]