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The map label for this gene is pcbC [H]

Identifier: 145299302

GI number: 145299302

Start: 2491924

End: 2492994

Strand: Direct

Name: pcbC [H]

Synonym: ASA_2346

Alternate gene names: 145299302

Gene position: 2491924-2492994 (Clockwise)

Preceding gene: 145299301

Following gene: 145299303

Centisome position: 52.99

GC content: 66.11

Gene sequence:

>1071_bases
ATGGAACATTCACCACTGCCGCTCATCGATCTCGCCGCCCTTGGTGGCGACCCCGAGGCTCGTCGCCACATGCTGGCCAA
GCTTGGCCGGGCGGCCCGCGACATCGGCTTTTTCTATCTGACAGGCCATGGCCTGAGCGAGGCGCAACAGCAAGAGACCC
TGGCGCTGGCGGCCCGTTTCTTCGCCCTGCCGGAACAGGAAAAACGGGCAGTGCAGATGGTACACTCTCCCCATTTTCGC
GGTTACAACCAGGTGGGCGCCGAACTCACCCGCCAGCGGCCGGACCGGCGCGAGCAGTTCGACATCATGAATGAGACGCC
TGCGCTGGCAAAAGACGAGATCCATGCCCCCTGGCAGCGGCTGATAGGCCCCAACCAGTGGCCTGCAGCCCTGCCCGAAA
TGAAAGCGCAGCTGCTGGCCTGGCAGGAGCGCCTCAGCGACATCACCCTCACCCTGCTCGACGCCTTCGCCGAGGTGCTG
GCGCAGCCGCAAGGCGTGTTCGATGCCAGCATTCGCGGCAAGCCCTACCAGCACATGAAGCTCATCCACTATCCGGGGCG
CGAAGCAGGTAGCAGCAGCCAGGGAGTGGGCGCCCACAAGGATCCCGGCTACCTGACCCTGGTGATGCAGGACGATCACT
CAGGGCTTGAGGTGGAGACGGCGGCAGGCTGGATCCCTGCGCCGCCCCTGCCGGGGGCCCTGGTGGTCAACATCGGCGAG
TTGCTTGAGCTGGCTTCCAACGGCTACCTCAAGGCCACCCTGCACAGGGTGGTGAGCCCGCCGCCGGGGGTATCGCGCCT
CTCCTGCGCCTTCTTTATGGCGGCGCGGCTCGATGCCACTGTGCCGCTGCTGACCCTGTCGCCGAGTCTGGCAGCGCAGG
CGCAAGGCCCCGAGAGCGACCCCGCCAACCCGCTCTTCTATCAGGTGGGGGAAAACGTGCTGAAAGGACGGTTGCGCTCC
CACCCGGATGTGGCGGCGCGCCACTATACCGCCGACCCGGCTTCAGCCAACGAACAGATGGCAAGCGGGCAGACAACAAG
CAGCGAGCGGCGCGAACCGCAGCCAGCCTGA

Upstream 100 bases:

>100_bases
TCTTTACCGGTCGGCCCGGTGTATCACCACCGACCCGCGCTGTCATGTTTGCACTGAGTCGTCGGGAAAGCCCCGATACT
CAGAAAATGAGGAGGTGCAC

Downstream 100 bases:

>100_bases
CTCTGCCATACCTATTAAACGGGGGATGCCGTGGCGTCCCGCCACCCGGATGACACAAGCAGTTAAGCCACAGCCTGGCA
ATGACGGAGTAATAGAATGA

Product: 2OG-Fe(II) oxygenase superfamily protein

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MEHSPLPLIDLAALGGDPEARRHMLAKLGRAARDIGFFYLTGHGLSEAQQQETLALAARFFALPEQEKRAVQMVHSPHFR
GYNQVGAELTRQRPDRREQFDIMNETPALAKDEIHAPWQRLIGPNQWPAALPEMKAQLLAWQERLSDITLTLLDAFAEVL
AQPQGVFDASIRGKPYQHMKLIHYPGREAGSSSQGVGAHKDPGYLTLVMQDDHSGLEVETAAGWIPAPPLPGALVVNIGE
LLELASNGYLKATLHRVVSPPPGVSRLSCAFFMAARLDATVPLLTLSPSLAAQAQGPESDPANPLFYQVGENVLKGRLRS
HPDVAARHYTADPASANEQMASGQTTSSERREPQPA

Sequences:

>Translated_356_residues
MEHSPLPLIDLAALGGDPEARRHMLAKLGRAARDIGFFYLTGHGLSEAQQQETLALAARFFALPEQEKRAVQMVHSPHFR
GYNQVGAELTRQRPDRREQFDIMNETPALAKDEIHAPWQRLIGPNQWPAALPEMKAQLLAWQERLSDITLTLLDAFAEVL
AQPQGVFDASIRGKPYQHMKLIHYPGREAGSSSQGVGAHKDPGYLTLVMQDDHSGLEVETAAGWIPAPPLPGALVVNIGE
LLELASNGYLKATLHRVVSPPPGVSRLSCAFFMAARLDATVPLLTLSPSLAAQAQGPESDPANPLFYQVGENVLKGRLRS
HPDVAARHYTADPASANEQMASGQTTSSERREPQPA
>Mature_356_residues
MEHSPLPLIDLAALGGDPEARRHMLAKLGRAARDIGFFYLTGHGLSEAQQQETLALAARFFALPEQEKRAVQMVHSPHFR
GYNQVGAELTRQRPDRREQFDIMNETPALAKDEIHAPWQRLIGPNQWPAALPEMKAQLLAWQERLSDITLTLLDAFAEVL
AQPQGVFDASIRGKPYQHMKLIHYPGREAGSSSQGVGAHKDPGYLTLVMQDDHSGLEVETAAGWIPAPPLPGALVVNIGE
LLELASNGYLKATLHRVVSPPPGVSRLSCAFFMAARLDATVPLLTLSPSLAAQAQGPESDPANPLFYQVGENVLKGRLRS
HPDVAARHYTADPASANEQMASGQTTSSERREPQPA

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI28572124, Length=287, Percent_Identity=26.4808362369338, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 38819; Mature: 38819

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHSPLPLIDLAALGGDPEARRHMLAKLGRAARDIGFFYLTGHGLSEAQQQETLALAARF
CCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHH
FALPEQEKRAVQMVHSPHFRGYNQVGAELTRQRPDRREQFDIMNETPALAKDEIHAPWQR
HHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHCCCHHH
LIGPNQWPAALPEMKAQLLAWQERLSDITLTLLDAFAEVLAQPQGVFDASIRGKPYQHMK
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHEE
LIHYPGREAGSSSQGVGAHKDPGYLTLVMQDDHSGLEVETAAGWIPAPPLPGALVVNIGE
EEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCHHEECHHH
LLELASNGYLKATLHRVVSPPPGVSRLSCAFFMAARLDATVPLLTLSPSLAAQAQGPESD
HHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCCCCCC
PANPLFYQVGENVLKGRLRSHPDVAARHYTADPASANEQMASGQTTSSERREPQPA
CCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHCCCCCCHHCCCCCCC
>Mature Secondary Structure
MEHSPLPLIDLAALGGDPEARRHMLAKLGRAARDIGFFYLTGHGLSEAQQQETLALAARF
CCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHHHH
FALPEQEKRAVQMVHSPHFRGYNQVGAELTRQRPDRREQFDIMNETPALAKDEIHAPWQR
HHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHCCCHHH
LIGPNQWPAALPEMKAQLLAWQERLSDITLTLLDAFAEVLAQPQGVFDASIRGKPYQHMK
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCHHHEE
LIHYPGREAGSSSQGVGAHKDPGYLTLVMQDDHSGLEVETAAGWIPAPPLPGALVVNIGE
EEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCHHEECHHH
LLELASNGYLKATLHRVVSPPPGVSRLSCAFFMAARLDATVPLLTLSPSLAAQAQGPESD
HHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHCCCCCCCC
PANPLFYQVGENVLKGRLRSHPDVAARHYTADPASANEQMASGQTTSSERREPQPA
CCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1901702 [H]