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The map label for this gene is dsbB

Identifier: 145299260

GI number: 145299260

Start: 2438984

End: 2439505

Strand: Direct

Name: dsbB

Synonym: ASA_2303

Alternate gene names: 145299260

Gene position: 2438984-2439505 (Clockwise)

Preceding gene: 145299259

Following gene: 145299264

Centisome position: 51.87

GC content: 57.47

Gene sequence:

>522_bases
ATGATTGAGTTCCTGCGTCGTATTGCCGCCCATCGACTGGCATGGGGTCTGCTTGCCGCGTCCGCTTTGTTCCTTGAGTT
GAGTGCCCTCTTCTTCCAATATGTGCTGGGTCTGCACCCATGTGTCATGTGCGTGTACGAGCGCCTCGCCATCCTGGGGG
TACTCTCGGCAGGATTGCTCGGCATGGTAGCGCCAGAGAAGTGGTATCTCCGCTGGAGTGCCCTCTTGCTCTGGGGCTAC
AGTGCCTTCCGTGGCCTTCAACTGGCACTGAAGCACGTGGATTATCAGATGAATCCTTCCCCATTCAACGTATGCAGCCC
TTTTGCCGACTTCCCCAGCTGGGCTCCTCTCGATCAGTGGCTGCCCTGGCTATTCTTCCCGGATGGAGATTGCAGCGAGA
TCAGCTGGCAATTCCTGAGCTTCTCCATGCCTCAGTGGCTTGTCGCCATCTTCGCCGCCTACCTGCTGGTGTTTGTGGTC
GTGACCATCGGCAATCTGGTCAAGGGACGGTGCTGCAGCTAA

Upstream 100 bases:

>100_bases
CAATGGATTCGTCTCACAATGCGGGATTGGGACAGCACCTTTCTTTTTATCCCCTGCTCTGCTCTAATTCAGCCACTGTT
TTTTCTGTGAGATCAACCAG

Downstream 100 bases:

>100_bases
TGCAGAGTAACAAGCATAAAAAAGGGAGCCATTGGCTCCCTTCTTCATGGGGCTGAATACCATCTTTTCCGCCTGCCTCT
GGCGTTTGTGATCCTGGCTA

Product: disulfide bond formation protein B

Products: NA

Alternate protein names: Disulfide oxidoreductase

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MIEFLRRIAAHRLAWGLLAASALFLELSALFFQYVLGLHPCVMCVYERLAILGVLSAGLLGMVAPEKWYLRWSALLLWGY
SAFRGLQLALKHVDYQMNPSPFNVCSPFADFPSWAPLDQWLPWLFFPDGDCSEISWQFLSFSMPQWLVAIFAAYLLVFVV
VTIGNLVKGRCCS

Sequences:

>Translated_173_residues
MIEFLRRIAAHRLAWGLLAASALFLELSALFFQYVLGLHPCVMCVYERLAILGVLSAGLLGMVAPEKWYLRWSALLLWGY
SAFRGLQLALKHVDYQMNPSPFNVCSPFADFPSWAPLDQWLPWLFFPDGDCSEISWQFLSFSMPQWLVAIFAAYLLVFVV
VTIGNLVKGRCCS
>Mature_173_residues
MIEFLRRIAAHRLAWGLLAASALFLELSALFFQYVLGLHPCVMCVYERLAILGVLSAGLLGMVAPEKWYLRWSALLLWGY
SAFRGLQLALKHVDYQMNPSPFNVCSPFADFPSWAPLDQWLPWLFFPDGDCSEISWQFLSFSMPQWLVAIFAAYLLVFVV
VTIGNLVKGRCCS

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family

Homologues:

Organism=Escherichia coli, GI1787433, Length=170, Percent_Identity=50.5882352941176, Blast_Score=171, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBB_AERS4 (A4SN81)

Other databases:

- EMBL:   CP000644
- RefSeq:   YP_001142101.1
- ProteinModelPortal:   A4SN81
- SMR:   A4SN81
- STRING:   A4SN81
- GeneID:   4997348
- GenomeReviews:   CP000644_GR
- KEGG:   asa:ASA_2303
- eggNOG:   COG1495
- HOGENOM:   HBG637909
- OMA:   ALYFQHV
- PhylomeDB:   A4SN81
- ProtClustDB:   PRK01749
- BioCyc:   ASAL382245:ASA_2303-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00286
- InterPro:   IPR003752
- InterPro:   IPR022920

Pfam domain/function: PF02600 DsbB

EC number: NA

Molecular weight: Translated: 19646; Mature: 19646

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1157a60c)-; HASH(0x10f72f74)-; HASH(0x10d960dc)-; HASH(0x1182ffe0)-;

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEFLRRIAAHRLAWGLLAASALFLELSALFFQYVLGLHPCVMCVYERLAILGVLSAGLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMVAPEKWYLRWSALLLWGYSAFRGLQLALKHVDYQMNPSPFNVCSPFADFPSWAPLDQW
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCHHHC
LPWLFFPDGDCSEISWQFLSFSMPQWLVAIFAAYLLVFVVVTIGNLVKGRCCS
CCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
>Mature Secondary Structure
MIEFLRRIAAHRLAWGLLAASALFLELSALFFQYVLGLHPCVMCVYERLAILGVLSAGLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMVAPEKWYLRWSALLLWGYSAFRGLQLALKHVDYQMNPSPFNVCSPFADFPSWAPLDQW
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCHHHC
LPWLFFPDGDCSEISWQFLSFSMPQWLVAIFAAYLLVFVVVTIGNLVKGRCCS
CCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA