Click here to switch to the map view.

The map label for this gene is prkA [H]

Identifier: 145299255

GI number: 145299255

Start: 2431159

End: 2433081

Strand: Direct

Name: prkA [H]

Synonym: ASA_2298

Alternate gene names: 145299255

Gene position: 2431159-2433081 (Clockwise)

Preceding gene: 145299254

Following gene: 145299256

Centisome position: 51.7

GC content: 55.02

Gene sequence:

>1923_bases
ATGGGCATCTTCGAGCATTATCAACAGCGATACGAGAAAGCCAGGGAAGAGGAGTACAGTATCCAGGAGTTTCTGGATAT
GTGTAAGCAGGACAAAGCCTGCTACGCCTCCGCTGCCGAACGCTTGCTGGTCGCCATCGGCGAGCCGGAAATGATCGATA
CCTCGGTCAATCCCAGACTCAGTCGCCTTTTTTCCAACCGCGTCGTTGCACGCTATCCCGCCTTCAAAGATTTCTACGGC
ATGGAAGAGGCCATCGAGCAGATCGTCTCCTACCTCAAGCACTCTGCCCAGGGGCTGGAAGAGAAGAAGCAGATCCTCTA
TCTGCTGGGACCGGTTGGCGGCGGCAAATCCTCTCTGGCTGAGAAGCTCAAATCCTTGATGCAAAAAGTGCCGGTCTATC
GCATCAAGGGCTCACCGGTCAATGACCACCCCTTCTGTCTGTTCGACATCGAAGAGGATGGCGAGCTGCTGGAAAAAGAG
TACGGCATTCCACGCCGCTATCTGCGACCCATCATGTCACCCTGGGTAGCCAAGCGACTGCACGAGTTCGGTGGCGACAT
CTCCAAGTTCAAGGTAGAGAAGGTCAACCCATCCATCCTCGATCAGATTGCCATCGCCAAGACAGAACCGGGTGATGACA
ACAACCAGGATATCTCCTCTCTGGTCGGCAAGGTCGACATCCGCATGCTGGAGCATTATGCCCAGGATGATGCAGATGCT
TACTCCTACTCAGGTGCGCTGTGCAAGGCGAACCAGGGGATCATGGAGTTCGTGGAGATGTTCAAAGCCCCCATCAAGGT
GCTGCATCCTCTGCTGACCGCGACCCAGGAAGGGAACTACAACGGCACCGAAGGGCTCTCCGCCCTGCCCTTCGACGGTA
TATTGCTGGCTCACTCCAACGAATCAGAGTGGCAGCAGTTCCGTAACAACAAGAACAACGAAGCCTTCCTCGACCGGGTT
TACATCGTCAAGGTGCCTTACTGCCTGCGCGTCTCGGAAGAGGTGAAGATATACGAAAAACTGCTGATCAACAGCGAGTT
GACTGACGCCAAGTGCGCACCTGGCACCTTGGAACTGTTGGGCCAGTTCTCCGTCCTCTCCCGACTGAAAGAGCCGGAAA
ACTCAAGCCTCTACTCCAAGATGCGGGTCTATGATGGCGAGAGCCTGAAAGATACGGATCCCAAGGCCAAGAGCTATCAG
GAGTACCGTGACTACGCCGGTGTGGATGAGGGCATGAATGGTCTCTCCACCCGCTTTGCGTTCAAGATCCTCTCTCGCGT
TTTCAACTTCGACCACGCGGAAGTGGCGGCCAACCCGGTACACCTCTTCTATGTGCTGGAGCAGCAGATAGAGCGCGAAC
AGTTCCCGCAGGAGCTGCACGATCGCTACCTTGAGTTCATCAAGGGTTATCTGACTCCGCGCTATGTGGAGTTCATCGGC
AAGGAGATCCAGACCGCCTACCTCGAATCCTATTCGGAGTACGGCCAGAACATCTTCGATCGCTACGTCACCTATGCAGA
CTTCTGGATCCAGGATCAGGAGTACCGAGACCCCGAGACCGGCCAGCTGTTTGACCGTGCATCGCTCAACAGCGAGCTGG
AGAAGATTGAAAAACCCGCCGGGATCAGCAACCCGAAAGATTTCCGCAACCAAATCGTCAACTTCGTGCTGCGAGCCCGG
GCCAACAATGCAGGCCGTAACCCCAACTGGACCAGTTACGAGAAGCTGCGCACCGTGATCGAGAAGAAGATGTTCTCCAA
CACGGAAGAGCTGCTGCCGGTTATCTCCTTCAACAGCAAAACCTCGGCTGAGGAGCAGAAGAAGCACGATAACTTTGTCG
AACGGATGATGGAGAAAGGCTACACCCGGAAACAGGTGCGACTGCTCTCCGAATGGTATCTCAGGGTACGCAAGTCATCC
TGA

Upstream 100 bases:

>100_bases
TGGATTACTGGGGGCTGTTGACCTAGGATTAATGAGGTAAACAGAACAAAAGTAGTGATCCACTCTTTTCAGGGTAAGCG
ACTATAACGAGGGCAAAGTT

Downstream 100 bases:

>100_bases
CCCTGCCGTGGTTCAAGGGGGAGTTATGGCGCATTTTATCGACCGCAGGCTCAACGGCAAAAACAAAAGCGCTGTCAATC
GGCAGCGCTTCATCCGCCGC

Product: serine protein kinase, PrkA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 639

Protein sequence:

>640_residues
MGIFEHYQQRYEKAREEEYSIQEFLDMCKQDKACYASAAERLLVAIGEPEMIDTSVNPRLSRLFSNRVVARYPAFKDFYG
MEEAIEQIVSYLKHSAQGLEEKKQILYLLGPVGGGKSSLAEKLKSLMQKVPVYRIKGSPVNDHPFCLFDIEEDGELLEKE
YGIPRRYLRPIMSPWVAKRLHEFGGDISKFKVEKVNPSILDQIAIAKTEPGDDNNQDISSLVGKVDIRMLEHYAQDDADA
YSYSGALCKANQGIMEFVEMFKAPIKVLHPLLTATQEGNYNGTEGLSALPFDGILLAHSNESEWQQFRNNKNNEAFLDRV
YIVKVPYCLRVSEEVKIYEKLLINSELTDAKCAPGTLELLGQFSVLSRLKEPENSSLYSKMRVYDGESLKDTDPKAKSYQ
EYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHAEVAANPVHLFYVLEQQIEREQFPQELHDRYLEFIKGYLTPRYVEFIG
KEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPETGQLFDRASLNSELEKIEKPAGISNPKDFRNQIVNFVLRAR
ANNAGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNSKTSAEEQKKHDNFVERMMEKGYTRKQVRLLSEWYLRVRKSS

Sequences:

>Translated_640_residues
MGIFEHYQQRYEKAREEEYSIQEFLDMCKQDKACYASAAERLLVAIGEPEMIDTSVNPRLSRLFSNRVVARYPAFKDFYG
MEEAIEQIVSYLKHSAQGLEEKKQILYLLGPVGGGKSSLAEKLKSLMQKVPVYRIKGSPVNDHPFCLFDIEEDGELLEKE
YGIPRRYLRPIMSPWVAKRLHEFGGDISKFKVEKVNPSILDQIAIAKTEPGDDNNQDISSLVGKVDIRMLEHYAQDDADA
YSYSGALCKANQGIMEFVEMFKAPIKVLHPLLTATQEGNYNGTEGLSALPFDGILLAHSNESEWQQFRNNKNNEAFLDRV
YIVKVPYCLRVSEEVKIYEKLLINSELTDAKCAPGTLELLGQFSVLSRLKEPENSSLYSKMRVYDGESLKDTDPKAKSYQ
EYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHAEVAANPVHLFYVLEQQIEREQFPQELHDRYLEFIKGYLTPRYVEFIG
KEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPETGQLFDRASLNSELEKIEKPAGISNPKDFRNQIVNFVLRAR
ANNAGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNSKTSAEEQKKHDNFVERMMEKGYTRKQVRLLSEWYLRVRKSS
>Mature_639_residues
GIFEHYQQRYEKAREEEYSIQEFLDMCKQDKACYASAAERLLVAIGEPEMIDTSVNPRLSRLFSNRVVARYPAFKDFYGM
EEAIEQIVSYLKHSAQGLEEKKQILYLLGPVGGGKSSLAEKLKSLMQKVPVYRIKGSPVNDHPFCLFDIEEDGELLEKEY
GIPRRYLRPIMSPWVAKRLHEFGGDISKFKVEKVNPSILDQIAIAKTEPGDDNNQDISSLVGKVDIRMLEHYAQDDADAY
SYSGALCKANQGIMEFVEMFKAPIKVLHPLLTATQEGNYNGTEGLSALPFDGILLAHSNESEWQQFRNNKNNEAFLDRVY
IVKVPYCLRVSEEVKIYEKLLINSELTDAKCAPGTLELLGQFSVLSRLKEPENSSLYSKMRVYDGESLKDTDPKAKSYQE
YRDYAGVDEGMNGLSTRFAFKILSRVFNFDHAEVAANPVHLFYVLEQQIEREQFPQELHDRYLEFIKGYLTPRYVEFIGK
EIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPETGQLFDRASLNSELEKIEKPAGISNPKDFRNQIVNFVLRARA
NNAGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNSKTSAEEQKKHDNFVERMMEKGYTRKQVRLLSEWYLRVRKSS

Specific function: Unknown

COG id: COG2766

COG function: function code T; Putative Ser protein kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prkA family [H]

Homologues:

Organism=Escherichia coli, GI1788083, Length=644, Percent_Identity=85.4037267080745, Blast_Score=1162, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013153
- InterPro:   IPR010650
- InterPro:   IPR016230 [H]

Pfam domain/function: PF08298 AAA_PrkA; PF06798 PrkA [H]

EC number: NA

Molecular weight: Translated: 74046; Mature: 73914

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIFEHYQQRYEKAREEEYSIQEFLDMCKQDKACYASAAERLLVAIGEPEMIDTSVNPRL
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
SRLFSNRVVARYPAFKDFYGMEEAIEQIVSYLKHSAQGLEEKKQILYLLGPVGGGKSSLA
HHHHHCCHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHEEEEECCCCCCHHHHH
EKLKSLMQKVPVYRIKGSPVNDHPFCLFDIEEDGELLEKEYGIPRRYLRPIMSPWVAKRL
HHHHHHHHHCCEEEECCCCCCCCCEEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
HEFGGDISKFKVEKVNPSILDQIAIAKTEPGDDNNQDISSLVGKVDIRMLEHYAQDDADA
HHHCCCHHHEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
YSYSGALCKANQGIMEFVEMFKAPIKVLHPLLTATQEGNYNGTEGLSALPFDGILLAHSN
HHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCC
ESEWQQFRNNKNNEAFLDRVYIVKVPYCLRVSEEVKIYEKLLINSELTDAKCAPGTLELL
HHHHHHHHCCCCCHHHHHEEHEEECCHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
GQFSVLSRLKEPENSSLYSKMRVYDGESLKDTDPKAKSYQEYRDYAGVDEGMNGLSTRFA
HHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHCCHHHHHHHH
FKILSRVFNFDHAEVAANPVHLFYVLEQQIEREQFPQELHDRYLEFIKGYLTPRYVEFIG
HHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHH
KEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPETGQLFDRASLNSELEKIEKPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
GISNPKDFRNQIVNFVLRARANNAGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNSK
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
TSAEEQKKHDNFVERMMEKGYTRKQVRLLSEWYLRVRKSS
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GIFEHYQQRYEKAREEEYSIQEFLDMCKQDKACYASAAERLLVAIGEPEMIDTSVNPRL
CHHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
SRLFSNRVVARYPAFKDFYGMEEAIEQIVSYLKHSAQGLEEKKQILYLLGPVGGGKSSLA
HHHHHCCHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHEEEEECCCCCCHHHHH
EKLKSLMQKVPVYRIKGSPVNDHPFCLFDIEEDGELLEKEYGIPRRYLRPIMSPWVAKRL
HHHHHHHHHCCEEEECCCCCCCCCEEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
HEFGGDISKFKVEKVNPSILDQIAIAKTEPGDDNNQDISSLVGKVDIRMLEHYAQDDADA
HHHCCCHHHEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
YSYSGALCKANQGIMEFVEMFKAPIKVLHPLLTATQEGNYNGTEGLSALPFDGILLAHSN
HHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCC
ESEWQQFRNNKNNEAFLDRVYIVKVPYCLRVSEEVKIYEKLLINSELTDAKCAPGTLELL
HHHHHHHHCCCCCHHHHHEEHEEECCHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
GQFSVLSRLKEPENSSLYSKMRVYDGESLKDTDPKAKSYQEYRDYAGVDEGMNGLSTRFA
HHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHCCHHHHHHHH
FKILSRVFNFDHAEVAANPVHLFYVLEQQIEREQFPQELHDRYLEFIKGYLTPRYVEFIG
HHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHH
KEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPETGQLFDRASLNSELEKIEKPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
GISNPKDFRNQIVNFVLRARANNAGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNSK
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
TSAEEQKKHDNFVERMMEKGYTRKQVRLLSEWYLRVRKSS
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]