Click here to switch to the map view.

The map label for this gene is mas [H]

Identifier: 145297068

GI number: 145297068

Start: 3289679

End: 3290545

Strand: Direct

Name: mas [H]

Synonym: cgR_2964

Alternate gene names: 145297068

Gene position: 3289679-3290545 (Clockwise)

Preceding gene: 145297066

Following gene: 145297069

Centisome position: 99.26

GC content: 59.98

Gene sequence:

>867_bases
ATGCGCGCAATCACTCACAACACTTTCGGCGACCCCGCCGACGTCCTACAGGTTACCGAGAAGGAAATTCCCAATCCCGG
CCCAGGTCAGGCACGTATTCGAGTGACGCTGGCAACCATCCACAACCATGATCTATGGACCGTGAAGGGCTCTTACGGCT
TCGTCCCAGATCTGCCGGCCGCCGCAGGCACCGAGGCAGTCGGCATCGTCGACGCCCTGGGCGAGGGCGTCGAGAGCTTG
CAGGTCGGTCAGCGTGTTGCGTCCAGCACCAGCTTTGGCATCTGGGCGGAGTACGCGCTTGTCGACGCCTCCGGCCTCAT
TCCCGTACCAGAGCAGCTCTCCGACGAAAGCGCAGCTCAGCTCGTCGCAATGCCTTTCAGCGCCATCAGCCTTCTTGATT
TCTTGGATATGAAACCAGGGGAGTGGCTGATCCAAAACTCCGCAAATGGTGCCGTCGGCCGCATACTCGCACAGCTGGCA
GAATCCCGTGGCATCCATGTCGTTGGCCTCGTCCGCCGTGACGCCGGTGTCCAAGAACTCGCTGCTCAAAACATCAGCGG
CGTCGTTTCCACTGAGACCCCAGGCTGGGAAAAGCAGGTCGAAGAAATCACCGGTGGCGCAAGCATCGCCGTCGCACTTG
ATTCCGTGGGTGGATCCTCCGCAGCTGACCTGGTGAAACTGCTTGGCGAAGGCGGCACCCTCGTCTCCTTCGGCGCCATG
GGCAACCCAGTCATGGAAATCCCATCCGGCCCCGTCATTTTCAAGCACATCACCGTCAAAGGCTTCTGGGGAAGCAAAGT
CAGCCGTGAAATGCCCGCAGAGAAGAAAACCCCAGTTGTTCGGCGAGCTCATTGCCCGCATACTTGA

Upstream 100 bases:

>100_bases
GCAAGTTTACTGCTCGGTCGTCACGGGGGGGGAATGGAAAAAGTACGCTTGGTGTTCATATAGCGAACCCATTTTCTATT
GCGAGGAGAGGAACACCACC

Downstream 100 bases:

>100_bases
TGGAACATTGACCCTTCCAGTTGATTCCACCTTTGATGCCGCTGACATCGTCTCGGCCGTGCGCGCCTCCAGCGAGCCTG
GCCGTGCCGGAAAAGTGCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MRAITHNTFGDPADVLQVTEKEIPNPGPGQARIRVTLATIHNHDLWTVKGSYGFVPDLPAAAGTEAVGIVDALGEGVESL
QVGQRVASSTSFGIWAEYALVDASGLIPVPEQLSDESAAQLVAMPFSAISLLDFLDMKPGEWLIQNSANGAVGRILAQLA
ESRGIHVVGLVRRDAGVQELAAQNISGVVSTETPGWEKQVEEITGGASIAVALDSVGGSSAADLVKLLGEGGTLVSFGAM
GNPVMEIPSGPVIFKHITVKGFWGSKVSREMPAEKKTPVVRRAHCPHT

Sequences:

>Translated_288_residues
MRAITHNTFGDPADVLQVTEKEIPNPGPGQARIRVTLATIHNHDLWTVKGSYGFVPDLPAAAGTEAVGIVDALGEGVESL
QVGQRVASSTSFGIWAEYALVDASGLIPVPEQLSDESAAQLVAMPFSAISLLDFLDMKPGEWLIQNSANGAVGRILAQLA
ESRGIHVVGLVRRDAGVQELAAQNISGVVSTETPGWEKQVEEITGGASIAVALDSVGGSSAADLVKLLGEGGTLVSFGAM
GNPVMEIPSGPVIFKHITVKGFWGSKVSREMPAEKKTPVVRRAHCPHT
>Mature_288_residues
MRAITHNTFGDPADVLQVTEKEIPNPGPGQARIRVTLATIHNHDLWTVKGSYGFVPDLPAAAGTEAVGIVDALGEGVESL
QVGQRVASSTSFGIWAEYALVDASGLIPVPEQLSDESAAQLVAMPFSAISLLDFLDMKPGEWLIQNSANGAVGRILAQLA
ESRGIHVVGLVRRDAGVQELAAQNISGVVSTETPGWEKQVEEITGGASIAVALDSVGGSSAADLVKLLGEGGTLVSFGAM
GNPVMEIPSGPVIFKHITVKGFWGSKVSREMPAEKKTPVVRRAHCPHT

Specific function: Catalyzes the elongation of N-fatty acyl-CoA with methylamalonyl-CoA (not malonyl-CoA) as the elongating agent to form mycocerosyl lipids [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Homo sapiens, GI67078404, Length=276, Percent_Identity=30.7971014492754, Blast_Score=137, Evalue=9e-33,
Organism=Homo sapiens, GI67078406, Length=239, Percent_Identity=31.7991631799163, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI194239674, Length=245, Percent_Identity=25.7142857142857, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI13236495, Length=245, Percent_Identity=25.7142857142857, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI24308257, Length=240, Percent_Identity=25, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI18379349, Length=212, Percent_Identity=28.3018867924528, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI194239676, Length=186, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI22538446, Length=285, Percent_Identity=24.9122807017544, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI22538444, Length=285, Percent_Identity=24.9122807017544, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1790485, Length=276, Percent_Identity=27.8985507246377, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787863, Length=139, Percent_Identity=31.6546762589928, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536829, Length=268, Percent_Identity=32.8358208955224, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17556000, Length=270, Percent_Identity=29.2592592592593, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17507255, Length=190, Percent_Identity=32.1052631578947, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319500, Length=242, Percent_Identity=27.6859504132231, Blast_Score=89, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6319520, Length=230, Percent_Identity=25.6521739130435, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45550423, Length=275, Percent_Identity=32.3636363636364, Blast_Score=148, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR013968
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00107 ADH_zinc_N; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]

EC number: =2.3.1.111 [H]

Molecular weight: Translated: 30129; Mature: 30129

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAITHNTFGDPADVLQVTEKEIPNPGPGQARIRVTLATIHNHDLWTVKGSYGFVPDLPA
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCEEEEECCCCCCCCCCCC
AAGTEAVGIVDALGEGVESLQVGQRVASSTSFGIWAEYALVDASGLIPVPEQLSDESAAQ
CCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHCCHHHHH
LVAMPFSAISLLDFLDMKPGEWLIQNSANGAVGRILAQLAESRGIHVVGLVRRDAGVQEL
HHHCCHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHH
AAQNISGVVSTETPGWEKQVEEITGGASIAVALDSVGGSSAADLVKLLGEGGTLVSFGAM
HHHCCCCEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEEECCC
GNPVMEIPSGPVIFKHITVKGFWGSKVSREMPAEKKTPVVRRAHCPHT
CCCEEECCCCCEEEEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRAITHNTFGDPADVLQVTEKEIPNPGPGQARIRVTLATIHNHDLWTVKGSYGFVPDLPA
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCEEEEECCCCCCCCCCCC
AAGTEAVGIVDALGEGVESLQVGQRVASSTSFGIWAEYALVDASGLIPVPEQLSDESAAQ
CCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHCCHHHHH
LVAMPFSAISLLDFLDMKPGEWLIQNSANGAVGRILAQLAESRGIHVVGLVRRDAGVQEL
HHHCCHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHH
AAQNISGVVSTETPGWEKQVEEITGGASIAVALDSVGGSSAADLVKLLGEGGTLVSFGAM
HHHCCCCEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEEECCC
GNPVMEIPSGPVIFKHITVKGFWGSKVSREMPAEKKTPVVRRAHCPHT
CCCEEECCCCCEEEEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1527058; 12788972 [H]