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The map label for this gene is kipR [H]

Identifier: 145297048

GI number: 145297048

Start: 3263480

End: 3264964

Strand: Direct

Name: kipR [H]

Synonym: cgR_2944

Alternate gene names: 145297048

Gene position: 3263480-3264964 (Clockwise)

Preceding gene: 145297043

Following gene: 145297049

Centisome position: 98.47

GC content: 54.75

Gene sequence:

>1485_bases
ATGCGAACAATTCAGCTACTCACCAAAGCAGGACTTTTAGTAGACGCACTTTCTGCAGGGCCAAATACTCATTCCGAGCT
GGCAAAACAGTTAAATGAGCCGAGATCGTCGATCTATCGAATAACGTCCTCGCTAGAGGAAGTCGGGTACGTCAACATCA
CCAGCAGTGGCTTGTTAGGGCTTGGCGTAAACATCCTCCACCTGGGCGAAAGTGCCGTTGACGCCCTGCTTAACAGAACT
TTATTGCGGGAAAAATTAGGCTGGCTCCGCGATCAGCTGGGCATGACCGCTTTCTTTTGCACCCTCCAAGATGACCGCAT
CATCAGTCTGGATTGGCAGGAGGGCGCAGATATTGATCTGATTTACCTCGCCCCTGGCCGCACGCTCCCGTCCCAAAAAG
GTGCAGTCTCCCATGTTCTCCAGGGCAAAGACCTGCACAAAGGGTGGAGTATTGATCACGGCGAGCTTGCCGCAGGAGTG
TCAACCTTAGCTGTCGCGGTGAAAAACACTAACGGCGATATCTTAGGAGCAGTGGCGGTAGCTGGGCTAAGTGCGAGCGT
TGAGAGCAAAATCGACACCATCAGAGACACATTGAAGGAAACTGCGTGCGCAATCACAGACATGCCTCCGGCCAAAACGC
AGGAATTCGATCCATCACGAATCGAGGAACCCAATTCACCTTCGGTGATCACCAAAGCGGCAACGCTCATGGATGTGCTC
CGCACTGAAGGTCCCACCAACTCCGCCCGCCTGGCCGAGCTGCTGGGGGAGCCGATCAGTTCGGTGTACAGAATGCTCCA
CACCTTAACCGTGATCGGGTGGGTTGAGCAGGACGGAAAGCGCGGTTCCTATCGTGTGGGCCTAGCCATGCTCACACTTG
CCGAATCGCAATTGCGCCATATGGATCTCCGCAAGATCGCCGCACTAACAATGCGGAAAATTCATGCACTCACTGGTGAA
ACCACATTTTTATGTGTTCGTCACGGCATTCGCGCGGTATGCATTGAGAGGGTCGATGGCGATCGTGTGAATAGTCGAGT
TCTCCAACTGGGAACCTCGCTGCCCCTCCATGTCGGTGCCGCACCGCGTGCGCTTCTCGCTTTTGAGGGGCGCAGGGCCT
GGGAAACATATGCCACAAACTTAGGATTCGAGGGCCACAACTGGTCTAAAGGACCGTCCAGAGCCGAGCTATTCCAACAC
TTGGACGAAGACCGCGACAAGGGTTTTTGCCTGGTAGACAATGAAATTACTCCCGGAATCGCCGCTGTGGGAGCACCGAT
TTACAACCATCGTGGTGAAGTCGTGGCAAGCCTGTCCATGAGTGGACTGCGGGACGGCATCCTCAGCGATACCGCCGACT
ACTCGGCCGTGGAACTGATCCTGCAGGGGTCTGCGGAGATTTCCCAAGCGCTGGGAGCGACCATTGAGCACAACGGGGGC
AACCAAAAACTACCCCAGGTAACTCCTCTGAGCATTGTGGTTTAA

Upstream 100 bases:

>100_bases
TTTTCGTCGATATAGTTACCCAAGACAACATGTTTGACCGCCATAAAACACCCCAAGTGGGGGCAAAATCAATAACACCC
TTTAGAAAATCGGATCAATT

Downstream 100 bases:

>100_bases
GCAATTCATTGACGTTCAAAGTGATGCGTGTCATGATTGAGACACTTGTCCGGTAGGTGAGTCTTCGTGAGATACCCCCG
GCCAGTCATACAGTTCAACC

Product: hypothetical protein

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MRTIQLLTKAGLLVDALSAGPNTHSELAKQLNEPRSSIYRITSSLEEVGYVNITSSGLLGLGVNILHLGESAVDALLNRT
LLREKLGWLRDQLGMTAFFCTLQDDRIISLDWQEGADIDLIYLAPGRTLPSQKGAVSHVLQGKDLHKGWSIDHGELAAGV
STLAVAVKNTNGDILGAVAVAGLSASVESKIDTIRDTLKETACAITDMPPAKTQEFDPSRIEEPNSPSVITKAATLMDVL
RTEGPTNSARLAELLGEPISSVYRMLHTLTVIGWVEQDGKRGSYRVGLAMLTLAESQLRHMDLRKIAALTMRKIHALTGE
TTFLCVRHGIRAVCIERVDGDRVNSRVLQLGTSLPLHVGAAPRALLAFEGRRAWETYATNLGFEGHNWSKGPSRAELFQH
LDEDRDKGFCLVDNEITPGIAAVGAPIYNHRGEVVASLSMSGLRDGILSDTADYSAVELILQGSAEISQALGATIEHNGG
NQKLPQVTPLSIVV

Sequences:

>Translated_494_residues
MRTIQLLTKAGLLVDALSAGPNTHSELAKQLNEPRSSIYRITSSLEEVGYVNITSSGLLGLGVNILHLGESAVDALLNRT
LLREKLGWLRDQLGMTAFFCTLQDDRIISLDWQEGADIDLIYLAPGRTLPSQKGAVSHVLQGKDLHKGWSIDHGELAAGV
STLAVAVKNTNGDILGAVAVAGLSASVESKIDTIRDTLKETACAITDMPPAKTQEFDPSRIEEPNSPSVITKAATLMDVL
RTEGPTNSARLAELLGEPISSVYRMLHTLTVIGWVEQDGKRGSYRVGLAMLTLAESQLRHMDLRKIAALTMRKIHALTGE
TTFLCVRHGIRAVCIERVDGDRVNSRVLQLGTSLPLHVGAAPRALLAFEGRRAWETYATNLGFEGHNWSKGPSRAELFQH
LDEDRDKGFCLVDNEITPGIAAVGAPIYNHRGEVVASLSMSGLRDGILSDTADYSAVELILQGSAEISQALGATIEHNGG
NQKLPQVTPLSIVV
>Mature_494_residues
MRTIQLLTKAGLLVDALSAGPNTHSELAKQLNEPRSSIYRITSSLEEVGYVNITSSGLLGLGVNILHLGESAVDALLNRT
LLREKLGWLRDQLGMTAFFCTLQDDRIISLDWQEGADIDLIYLAPGRTLPSQKGAVSHVLQGKDLHKGWSIDHGELAAGV
STLAVAVKNTNGDILGAVAVAGLSASVESKIDTIRDTLKETACAITDMPPAKTQEFDPSRIEEPNSPSVITKAATLMDVL
RTEGPTNSARLAELLGEPISSVYRMLHTLTVIGWVEQDGKRGSYRVGLAMLTLAESQLRHMDLRKIAALTMRKIHALTGE
TTFLCVRHGIRAVCIERVDGDRVNSRVLQLGTSLPLHVGAAPRALLAFEGRRAWETYATNLGFEGHNWSKGPSRAELFQH
LDEDRDKGFCLVDNEITPGIAAVGAPIYNHRGEVVASLSMSGLRDGILSDTADYSAVELILQGSAEISQALGATIEHNGG
NQKLPQVTPLSIVV

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=228, Percent_Identity=27.6315789473684, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1786715, Length=239, Percent_Identity=26.3598326359833, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788131, Length=223, Percent_Identity=26.9058295964126, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082359, Length=247, Percent_Identity=23.8866396761134, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790752, Length=233, Percent_Identity=23.6051502145923, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789999, Length=240, Percent_Identity=23.75, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1788581, Length=250, Percent_Identity=24, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 53236; Mature: 53236

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTIQLLTKAGLLVDALSAGPNTHSELAKQLNEPRSSIYRITSSLEEVGYVNITSSGLLG
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCHH
LGVNILHLGESAVDALLNRTLLREKLGWLRDQLGMTAFFCTLQDDRIISLDWQEGADIDL
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEECCCCCCEEE
IYLAPGRTLPSQKGAVSHVLQGKDLHKGWSIDHGELAAGVSTLAVAVKNTNGDILGAVAV
EEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHCHHEEEEEEECCCCCEEHHHHH
AGLSASVESKIDTIRDTLKETACAITDMPPAKTQEFDPSRIEEPNSPSVITKAATLMDVL
HHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHH
RTEGPTNSARLAELLGEPISSVYRMLHTLTVIGWVEQDGKRGSYRVGLAMLTLAESQLRH
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHECCCCCCCCEEHHHHHHHHHHHHHHH
MDLRKIAALTMRKIHALTGETTFLCVRHGIRAVCIERVDGDRVNSRVLQLGTSLPLHVGA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHCCCCCEEECC
APRALLAFEGRRAWETYATNLGFEGHNWSKGPSRAELFQHLDEDRDKGFCLVDNEITPGI
CCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCH
AAVGAPIYNHRGEVVASLSMSGLRDGILSDTADYSAVELILQGSAEISQALGATIEHNGG
HHHCCCHHCCCCCEEEHHHHHHHHCCHHCCCCCHHHHHHHHCCCHHHHHHHCCEEEECCC
NQKLPQVTPLSIVV
CCCCCCCCCCEEEC
>Mature Secondary Structure
MRTIQLLTKAGLLVDALSAGPNTHSELAKQLNEPRSSIYRITSSLEEVGYVNITSSGLLG
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEECCCCHH
LGVNILHLGESAVDALLNRTLLREKLGWLRDQLGMTAFFCTLQDDRIISLDWQEGADIDL
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEEEEECCCCCCEEE
IYLAPGRTLPSQKGAVSHVLQGKDLHKGWSIDHGELAAGVSTLAVAVKNTNGDILGAVAV
EEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHCHHEEEEEEECCCCCEEHHHHH
AGLSASVESKIDTIRDTLKETACAITDMPPAKTQEFDPSRIEEPNSPSVITKAATLMDVL
HHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHH
RTEGPTNSARLAELLGEPISSVYRMLHTLTVIGWVEQDGKRGSYRVGLAMLTLAESQLRH
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHECCCCCCCCEEHHHHHHHHHHHHHHH
MDLRKIAALTMRKIHALTGETTFLCVRHGIRAVCIERVDGDRVNSRVLQLGTSLPLHVGA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHCCCCHHHHHHHHHCCCCCEEECC
APRALLAFEGRRAWETYATNLGFEGHNWSKGPSRAELFQHLDEDRDKGFCLVDNEITPGI
CCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCCCCH
AAVGAPIYNHRGEVVASLSMSGLRDGILSDTADYSAVELILQGSAEISQALGATIEHNGG
HHHCCCHHCCCCCEEEHHHHHHHHCCHHCCCCCHHHHHHHHCCCHHHHHHHCCEEEECCC
NQKLPQVTPLSIVV
CCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]