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The map label for this gene is yclF [H]

Identifier: 145297042

GI number: 145297042

Start: 3256794

End: 3258320

Strand: Reverse

Name: yclF [H]

Synonym: cgR_2939

Alternate gene names: 145297042

Gene position: 3258320-3256794 (Counterclockwise)

Preceding gene: 145297044

Following gene: 145297039

Centisome position: 98.31

GC content: 55.86

Gene sequence:

>1527_bases
ATGAACACCGACACAACTCAAGACGGTGTGAGTCCTGAACCTTCCGACCCCCACCTAGGGTCTGAAGTGGCGGAAACTCA
CCGCGAAAAGAAATTCTTCGGCCAGCCTTGGGGGCTGGCAAACCTCTTCGGCGTGGAGATGTGGGAGCGATTCAGCTTCT
ACGGCATGCAGTCCATCCTTGCTTTCTATCTGTACTACTCCGTTACCGATGGCGGACTTGGTATGAATCAGACAGCTGCA
CTGTCCATTGTGGGCGCCTACGGCGGCTTCGTCTACATGACCTCCCTCGTGGCTTCGTTCATTGCAGACCGAGTATTGGG
TTCTGAACGTACACTCTTCTACTCCGCGATCATCGTCATGCTGGGCCACATTGCCCTGGCCTTGATTCCGGGATATACGG
GGCTGTCCATCGGCTTGGTCCTCATCGGCCTTGGCTCAGGTGGCGTGAAGACGGCAGCGCAGGTTGTGCTGGGCCAGCTG
TACTCACGCACGGACACGCGTCGAGACGCAGGCTTCTCCATCTTCTACATGGGCGTCAACCTCGGTGGCCTCTTTGGCCC
GCTGATCACCAACGCTCTGTGGGGATGGGGAGGATTCCACTGGGGCTTCGGTATCGCCGCAGTCGGCATGGCTTTGGGTC
TCATCCAATACGTGGCGATGCGTAAAACCACCATCGGTGCGGCAGGGCATACTGTTCCTAACCCACTGCCTAAGAATGAA
TATGCGCGCTGGATTATCGGCGCAGTCGTGGTTGTCGCAGCAGTTGTCGCTCTCATCGCAACGGGCATCATCAAGCTGGA
ATGGCTGTCCAACATCACCGCAGCGATCGCACTGATTGCGGCTATTGCTCTGCTTGCTCAGATGTACGTTTCCCCACTGA
CCACCGCAGCGGAAAAGTCCCGCTTGTTGGGATTCATCCCAATGTTCATCGGTGGCGTGCTTTTCTTCGCGATCTTCCAA
ACCCAGTTCACCGTCCTCGCGGTTTACTCCGACACCCGCCTGGACCGTAACTTCTTCGGCATTGATCTTCCTCCAGGATT
GATCAACTCCTTCAATCCAATCTTCATCATCATCTTCTCCGGAATCTTTGCCACCTTGTGGACAAAACTCGGAGCAAAGC
AGTGGTCTACTGCAGTGAAGTTCGGTGTCGCCAACATTGTCATTGGTTGCGCGCTGTTCTTCTTCCTGCCGTTCGCCGGC
GGTGCAGAGAACTCTACCCCAATGGCACTGATCATTTGGGTCTACTTCCTCTTCACCATCGCTGAGCTTCTGCTCTCCCC
TGTCGGCAACTCACTTGCAACCAAGGTCGCACCCGAGGCATTCCAGTCCCGCATGTTCGCCGTGTGGCTGATGGCTGTCT
CCATGGGTACGTCCCTGTCCGGCACCCTGGGTGGTTACTACGATCCAACCGATGCAGGATCTGAAAAGGTCTTCTTCATT
ACCGTTGGCGTTGCAGCCATCGTTCTTGGTGCAATCGTCATTGCAGCCAAGGGCTGGGTGCTGAAGAAGTTCATCGACGT
CCGATAG

Upstream 100 bases:

>100_bases
GATCAACTTAAGCCTCTAGCTATTTTCAACTGTGTTTCAGTTGCGGGATCGTTGGGTGCCTAATTGGAGTTGTGCTTTTA
GGTGGAGGATCATAGAGGTT

Downstream 100 bases:

>100_bases
GCCTCACAAAGACTCAAAACAAAAACCGCGTGCCTTCTCTAAACAGAGAAGGCACGCGGTTTTTAGATGCGACGAACCTT
AGTTCTTCAAGGTCTGATCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MNTDTTQDGVSPEPSDPHLGSEVAETHREKKFFGQPWGLANLFGVEMWERFSFYGMQSILAFYLYYSVTDGGLGMNQTAA
LSIVGAYGGFVYMTSLVASFIADRVLGSERTLFYSAIIVMLGHIALALIPGYTGLSIGLVLIGLGSGGVKTAAQVVLGQL
YSRTDTRRDAGFSIFYMGVNLGGLFGPLITNALWGWGGFHWGFGIAAVGMALGLIQYVAMRKTTIGAAGHTVPNPLPKNE
YARWIIGAVVVVAAVVALIATGIIKLEWLSNITAAIALIAAIALLAQMYVSPLTTAAEKSRLLGFIPMFIGGVLFFAIFQ
TQFTVLAVYSDTRLDRNFFGIDLPPGLINSFNPIFIIIFSGIFATLWTKLGAKQWSTAVKFGVANIVIGCALFFFLPFAG
GAENSTPMALIIWVYFLFTIAELLLSPVGNSLATKVAPEAFQSRMFAVWLMAVSMGTSLSGTLGGYYDPTDAGSEKVFFI
TVGVAAIVLGAIVIAAKGWVLKKFIDVR

Sequences:

>Translated_508_residues
MNTDTTQDGVSPEPSDPHLGSEVAETHREKKFFGQPWGLANLFGVEMWERFSFYGMQSILAFYLYYSVTDGGLGMNQTAA
LSIVGAYGGFVYMTSLVASFIADRVLGSERTLFYSAIIVMLGHIALALIPGYTGLSIGLVLIGLGSGGVKTAAQVVLGQL
YSRTDTRRDAGFSIFYMGVNLGGLFGPLITNALWGWGGFHWGFGIAAVGMALGLIQYVAMRKTTIGAAGHTVPNPLPKNE
YARWIIGAVVVVAAVVALIATGIIKLEWLSNITAAIALIAAIALLAQMYVSPLTTAAEKSRLLGFIPMFIGGVLFFAIFQ
TQFTVLAVYSDTRLDRNFFGIDLPPGLINSFNPIFIIIFSGIFATLWTKLGAKQWSTAVKFGVANIVIGCALFFFLPFAG
GAENSTPMALIIWVYFLFTIAELLLSPVGNSLATKVAPEAFQSRMFAVWLMAVSMGTSLSGTLGGYYDPTDAGSEKVFFI
TVGVAAIVLGAIVIAAKGWVLKKFIDVR
>Mature_508_residues
MNTDTTQDGVSPEPSDPHLGSEVAETHREKKFFGQPWGLANLFGVEMWERFSFYGMQSILAFYLYYSVTDGGLGMNQTAA
LSIVGAYGGFVYMTSLVASFIADRVLGSERTLFYSAIIVMLGHIALALIPGYTGLSIGLVLIGLGSGGVKTAAQVVLGQL
YSRTDTRRDAGFSIFYMGVNLGGLFGPLITNALWGWGGFHWGFGIAAVGMALGLIQYVAMRKTTIGAAGHTVPNPLPKNE
YARWIIGAVVVVAAVVALIATGIIKLEWLSNITAAIALIAAIALLAQMYVSPLTTAAEKSRLLGFIPMFIGGVLFFAIFQ
TQFTVLAVYSDTRLDRNFFGIDLPPGLINSFNPIFIIIFSGIFATLWTKLGAKQWSTAVKFGVANIVIGCALFFFLPFAG
GAENSTPMALIIWVYFLFTIAELLLSPVGNSLATKVAPEAFQSRMFAVWLMAVSMGTSLSGTLGGYYDPTDAGSEKVFFI
TVGVAAIVLGAIVIAAKGWVLKKFIDVR

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI226371746, Length=362, Percent_Identity=27.6243093922652, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI4827008, Length=219, Percent_Identity=29.2237442922374, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI226371748, Length=353, Percent_Identity=25.4957507082153, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1790572, Length=408, Percent_Identity=26.9607843137255, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787922, Length=475, Percent_Identity=22.9473684210526, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1786927, Length=350, Percent_Identity=29.7142857142857, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1789911, Length=480, Percent_Identity=22.7083333333333, Blast_Score=125, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI71987453, Length=353, Percent_Identity=25.7790368271955, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17569141, Length=354, Percent_Identity=23.728813559322, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24639585, Length=349, Percent_Identity=25.214899713467, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24639583, Length=349, Percent_Identity=25.214899713467, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24639581, Length=349, Percent_Identity=25.214899713467, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28571098, Length=383, Percent_Identity=23.4986945169713, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571102, Length=383, Percent_Identity=23.2375979112272, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571100, Length=383, Percent_Identity=23.2375979112272, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 54403; Mature: 54403

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTDTTQDGVSPEPSDPHLGSEVAETHREKKFFGQPWGLANLFGVEMWERFSFYGMQSIL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AFYLYYSVTDGGLGMNQTAALSIVGAYGGFVYMTSLVASFIADRVLGSERTLFYSAIIVM
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LGHIALALIPGYTGLSIGLVLIGLGSGGVKTAAQVVLGQLYSRTDTRRDAGFSIFYMGVN
HHHHHHHHHCCCCHHHEEHHHEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCC
LGGLFGPLITNALWGWGGFHWGFGIAAVGMALGLIQYVAMRKTTIGAAGHTVPNPLPKNE
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
YARWIIGAVVVVAAVVALIATGIIKLEWLSNITAAIALIAAIALLAQMYVSPLTTAAEKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLGFIPMFIGGVLFFAIFQTQFTVLAVYSDTRLDRNFFGIDLPPGLINSFNPIFIIIFS
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCHHHCCCCHHHHHHHH
GIFATLWTKLGAKQWSTAVKFGVANIVIGCALFFFLPFAGGAENSTPMALIIWVYFLFTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
AELLLSPVGNSLATKVAPEAFQSRMFAVWLMAVSMGTSLSGTLGGYYDPTDAGSEKVFFI
HHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEE
TVGVAAIVLGAIVIAAKGWVLKKFIDVR
EHHHHHHHHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure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EHHHHHHHHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]