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The map label for this gene is namA [H]

Identifier: 145297034

GI number: 145297034

Start: 3252624

End: 3253718

Strand: Direct

Name: namA [H]

Synonym: cgR_2931

Alternate gene names: 145297034

Gene position: 3252624-3253718 (Clockwise)

Preceding gene: 145297032

Following gene: 145297035

Centisome position: 98.14

GC content: 56.44

Gene sequence:

>1095_bases
ATGGAGCCTTTGGTGTCCAAGCTGTTTACCCCAATTCAAATCCGCGACATCACCATCCCCAACCGCGTGTGGATGTCACC
GATGTGCACCTACTCTGCAGCCACCGGTTCAGGTCTTCCCACCGATTTTCACCAGGCTCATTACGCAGCTCGCGCAGCAG
GTGGTGTCGGATTAGTCATGGTTGAAGCAACTGGAGTGAGCCCCGTAGCTCCCATCTCCCCAGTCGACCTTGGACTTTGG
AGCCATGACCAAATTGAACCATTCTCCCGAGTGACAGCAGCTATTCGCGCCGGTGGGGCAGTACCGGCCGTTCAATTAGC
CCATGCTGGCCGCAAGGCATCCACCGATGCTCCGTGGAATGGTGGCGGATATGTTGGACCAGAAACCAATGGATGGGAGA
CTGTCGGCCCCAGCCCTCTGGCATTCCCAGGTTTGCCTGCTCCGCGCGAGCTGACGGTTTCAGAAATCCAAGAGGTTGTG
CAGCAGTTCGCTAGCGCCGCCGTTCGTGCAGATCAGGCTGGTTTTGATGTCGTGGAAATTCACGCAGCACACGGCTACCT
TTTGCATAACTTCCTTTCTCCGATCTCCAACAAGCGCACCGATTCATACGGCGGATCTTTAGAAAACCGCGCTCGCATCG
TGCTCGAAGTCATTGATGCAATCCGCGCAGTGTGGCCAGAGGAAAAGCCTGTATTCATGCGCATTTCCACCACCGACTGG
GTAGAGGAAAACCCACAGGATGATCGCGAGTCCTGGACGCTGAGCCAAAGCAGGCAGCTGGCTTTGTGGGCATCCGAGCG
CGGAGTTGATTTGATCGATGCCTCTTCTGGTGGCCTCGACATCGTCCCCATTCCGCATGACCGCGATTACCAAACCGCGA
AGGCCGCAGATCTTCACGCAAGGACCGGAGTGACAGTCGCTGCTGTGGGGCGCATTGATGACGCCCAAACTGCGCACAAT
TTGGTTGATTCTGGCGATGTCAATGCAGTTTTCCTCGGCCGTCCGCTGCTCAAGGATCCTTCCTGGGCAAACCAAGCAGC
CCTCGCGCTAGGTGCGGAACCCAGGTATGTTCGCCAATACGACTACGTACTTTAA

Upstream 100 bases:

>100_bases
GTATTGAATTTAGGTACGACTCTAATCGTACCTTGCCCTTAAGCCAAGCTAGTTGTACGATCAAACTCGTTGTATGGTAA
ACGTCGTACTAGTCGATTGA

Downstream 100 bases:

>100_bases
AGGAGAGTTGACATGAAGGTTTTCATCATCGGCGCTGCGGGTGGCATCGGCAATCGACTTTCCAGCCTGCTTCACGCCAG
GGGAGATGCAGTTAGCGGCA

Product: hypothetical protein

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MEPLVSKLFTPIQIRDITIPNRVWMSPMCTYSAATGSGLPTDFHQAHYAARAAGGVGLVMVEATGVSPVAPISPVDLGLW
SHDQIEPFSRVTAAIRAGGAVPAVQLAHAGRKASTDAPWNGGGYVGPETNGWETVGPSPLAFPGLPAPRELTVSEIQEVV
QQFASAAVRADQAGFDVVEIHAAHGYLLHNFLSPISNKRTDSYGGSLENRARIVLEVIDAIRAVWPEEKPVFMRISTTDW
VEENPQDDRESWTLSQSRQLALWASERGVDLIDASSGGLDIVPIPHDRDYQTAKAADLHARTGVTVAAVGRIDDAQTAHN
LVDSGDVNAVFLGRPLLKDPSWANQAALALGAEPRYVRQYDYVL

Sequences:

>Translated_364_residues
MEPLVSKLFTPIQIRDITIPNRVWMSPMCTYSAATGSGLPTDFHQAHYAARAAGGVGLVMVEATGVSPVAPISPVDLGLW
SHDQIEPFSRVTAAIRAGGAVPAVQLAHAGRKASTDAPWNGGGYVGPETNGWETVGPSPLAFPGLPAPRELTVSEIQEVV
QQFASAAVRADQAGFDVVEIHAAHGYLLHNFLSPISNKRTDSYGGSLENRARIVLEVIDAIRAVWPEEKPVFMRISTTDW
VEENPQDDRESWTLSQSRQLALWASERGVDLIDASSGGLDIVPIPHDRDYQTAKAADLHARTGVTVAAVGRIDDAQTAHN
LVDSGDVNAVFLGRPLLKDPSWANQAALALGAEPRYVRQYDYVL
>Mature_364_residues
MEPLVSKLFTPIQIRDITIPNRVWMSPMCTYSAATGSGLPTDFHQAHYAARAAGGVGLVMVEATGVSPVAPISPVDLGLW
SHDQIEPFSRVTAAIRAGGAVPAVQLAHAGRKASTDAPWNGGGYVGPETNGWETVGPSPLAFPGLPAPRELTVSEIQEVV
QQFASAAVRADQAGFDVVEIHAAHGYLLHNFLSPISNKRTDSYGGSLENRARIVLEVIDAIRAVWPEEKPVFMRISTTDW
VEENPQDDRESWTLSQSRQLALWASERGVDLIDASSGGLDIVPIPHDRDYQTAKAADLHARTGVTVAAVGRIDDAQTAHN
LVDSGDVNAVFLGRPLLKDPSWANQAALALGAEPRYVRQYDYVL

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=353, Percent_Identity=32.0113314447592, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1789463, Length=346, Percent_Identity=27.7456647398844, Blast_Score=115, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI72001454, Length=318, Percent_Identity=31.1320754716981, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17559804, Length=320, Percent_Identity=29.6875, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17559802, Length=319, Percent_Identity=29.4670846394984, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17540738, Length=294, Percent_Identity=30.952380952381, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17564188, Length=319, Percent_Identity=27.8996865203762, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17565138, Length=343, Percent_Identity=26.8221574344023, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17566914, Length=324, Percent_Identity=28.7037037037037, Blast_Score=105, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6321973, Length=234, Percent_Identity=35.042735042735, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6325086, Length=234, Percent_Identity=32.9059829059829, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39166; Mature: 39166

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPLVSKLFTPIQIRDITIPNRVWMSPMCTYSAATGSGLPTDFHQAHYAARAAGGVGLVM
CCHHHHHHCCCEEEEEEECCCHHHCCCHHEECCCCCCCCCCHHHHHHHHHHHCCCEEEEE
VEATGVSPVAPISPVDLGLWSHDQIEPFSRVTAAIRAGGAVPAVQLAHAGRKASTDAPWN
EEECCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCC
GGGYVGPETNGWETVGPSPLAFPGLPAPRELTVSEIQEVVQQFASAAVRADQAGFDVVEI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
HAAHGYLLHNFLSPISNKRTDSYGGSLENRARIVLEVIDAIRAVWPEEKPVFMRISTTDW
ECCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
VEENPQDDRESWTLSQSRQLALWASERGVDLIDASSGGLDIVPIPHDRDYQTAKAADLHA
CCCCCCCCHHHCCCCCCCEEEEEECCCCCEEEECCCCCEEEEECCCCCCCCCHHHHHHHH
RTGVTVAAVGRIDDAQTAHNLVDSGDVNAVFLGRPLLKDPSWANQAALALGAEPRYVRQY
CCCCEEEEECCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCEEEECCCCCHHHHC
DYVL
CCCC
>Mature Secondary Structure
MEPLVSKLFTPIQIRDITIPNRVWMSPMCTYSAATGSGLPTDFHQAHYAARAAGGVGLVM
CCHHHHHHCCCEEEEEEECCCHHHCCCHHEECCCCCCCCCCHHHHHHHHHHHCCCEEEEE
VEATGVSPVAPISPVDLGLWSHDQIEPFSRVTAAIRAGGAVPAVQLAHAGRKASTDAPWN
EEECCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCC
GGGYVGPETNGWETVGPSPLAFPGLPAPRELTVSEIQEVVQQFASAAVRADQAGFDVVEI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
HAAHGYLLHNFLSPISNKRTDSYGGSLENRARIVLEVIDAIRAVWPEEKPVFMRISTTDW
ECCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
VEENPQDDRESWTLSQSRQLALWASERGVDLIDASSGGLDIVPIPHDRDYQTAKAADLHA
CCCCCCCCHHHCCCCCCCEEEEEECCCCCEEEECCCCCEEEEECCCCCCCCCHHHHHHHH
RTGVTVAAVGRIDDAQTAHNLVDSGDVNAVFLGRPLLKDPSWANQAALALGAEPRYVRQY
CCCCEEEEECCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCEEEECCCCCHHHHC
DYVL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]