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The map label for this gene is malY [C]

Identifier: 145296901

GI number: 145296901

Start: 3110233

End: 3111411

Strand: Direct

Name: malY [C]

Synonym: cgR_2801

Alternate gene names: 145296901

Gene position: 3110233-3111411 (Clockwise)

Preceding gene: 145296900

Following gene: 145296902

Centisome position: 93.85

GC content: 49.02

Gene sequence:

>1179_bases
GTGTTTAACACCTTGTCTTTGGAACAGCTCCGTCAGCGCGGCACCCTCAAATGGACTACTTTCGATCAAGATGTTCTTCC
ATTATGGGTCGCGGAAACAGATTTCGATACTTGCCCTGCGGTGGTTGAGTCTGTTCAAAATGCCGTGAATCTTCAGCAAT
TTGGATACCCTTCCAACAGCAATAAGCTTGCCGATGCCCTCACCGCATGGTGCGCTACCCGCTACAACTGGGAGATCAAC
CCAGCGTGGGTGCATGATTTACCGGATGTTCTCAAGGGTATTGAAGTATCAATCAACCACTTTACGGTGGCTGGATCTGC
GATTATCCTTCCGACTCCTGCATATATGCCGTTTTACGATGTGCTCGAAGTTACCGGCCGGAAGATCAATCAAGTCCCGA
TGATTTTTGAAGACGGACGTTATTCCTTTGACTTAGTGGCAATCGAAGAGGCTTTCGCCAATGGAGCTGGCGGACTCATT
GTGTGCAATCCTTACAACCCTTTGGGAGCTACTTTCACGGCCGAAGAACTCCAGTCCTTAGCCCAGTTGGCTCAGAAGTA
CGAGGCGCGGATTATCTCTGATGAGATCCATGCTCCACTAACTTTGGATGAAGCCCACATCCCCACTGCGTCGGTTTCTG
ATACAGCGGCAGAAGTCACCATCACCATTACGGCGACTTCCAAGGGCTGGAATACTCCAGGCCTGAAATGCGCCCAGCTC
ATCTTGCATAATGAGCGCGATGAAAAAACCTGGAAGAAAATTAATTCACTTCGCTCGCATGGCGCATCTACACTCGGCAT
TGCTGCCTCGATTGGAGCATATGAAAAGGGTGGTGAGTGGCTCGATACGGAGATTGAATACCTCCGCAAGAACCGTCAGT
TCTTGCTGGATAACTTAGGTCAAGCTATTCCTGGCATTGGTTTCAATAAGCCTCAAGCAACTTATCTCGCATGGCTTGAT
TTCAGCGAGGTGGAGGGCCTTAACGACCAAGATCCTGCTGCATACCTTCTTGAACATGCGAGGGTTGCTTTGAATCCAGG
ACTTCCGTTTGGCCCAGGAGGTGAGAATCATGCTCGTCTAAATTTCGGAACGTCGCAAGAAATCCTTGAAGAATTTTTGG
ATCGAACCCGCACCGCCTTTTCTTCTTCACCCACCAAGAATGAATTCATTTACCTTTAG

Upstream 100 bases:

>100_bases
ACACTGTTCTACATCGGCATGAAAGAAACGGCATTCAAGCCACTACCGAAGTAAGTCACTTCCCCCAAAAGTCACCACAC
CTATTTAGAAAGAATCTTCA

Downstream 100 bases:

>100_bases
AAAGGCACTTTCCCATGTCTTACCACGATCACAGCGACATCGAATACCTCAAGAAGATCGGCGCCAACTCCCCTGACGCG
TTCAAAGCCTTTGCCCATTT

Product: hypothetical protein

Products: NA

Alternate protein names: CBL; Beta-cystathionase; Cysteine lyase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MFNTLSLEQLRQRGTLKWTTFDQDVLPLWVAETDFDTCPAVVESVQNAVNLQQFGYPSNSNKLADALTAWCATRYNWEIN
PAWVHDLPDVLKGIEVSINHFTVAGSAIILPTPAYMPFYDVLEVTGRKINQVPMIFEDGRYSFDLVAIEEAFANGAGGLI
VCNPYNPLGATFTAEELQSLAQLAQKYEARIISDEIHAPLTLDEAHIPTASVSDTAAEVTITITATSKGWNTPGLKCAQL
ILHNERDEKTWKKINSLRSHGASTLGIAASIGAYEKGGEWLDTEIEYLRKNRQFLLDNLGQAIPGIGFNKPQATYLAWLD
FSEVEGLNDQDPAAYLLEHARVALNPGLPFGPGGENHARLNFGTSQEILEEFLDRTRTAFSSSPTKNEFIYL

Sequences:

>Translated_392_residues
MFNTLSLEQLRQRGTLKWTTFDQDVLPLWVAETDFDTCPAVVESVQNAVNLQQFGYPSNSNKLADALTAWCATRYNWEIN
PAWVHDLPDVLKGIEVSINHFTVAGSAIILPTPAYMPFYDVLEVTGRKINQVPMIFEDGRYSFDLVAIEEAFANGAGGLI
VCNPYNPLGATFTAEELQSLAQLAQKYEARIISDEIHAPLTLDEAHIPTASVSDTAAEVTITITATSKGWNTPGLKCAQL
ILHNERDEKTWKKINSLRSHGASTLGIAASIGAYEKGGEWLDTEIEYLRKNRQFLLDNLGQAIPGIGFNKPQATYLAWLD
FSEVEGLNDQDPAAYLLEHARVALNPGLPFGPGGENHARLNFGTSQEILEEFLDRTRTAFSSSPTKNEFIYL
>Mature_392_residues
MFNTLSLEQLRQRGTLKWTTFDQDVLPLWVAETDFDTCPAVVESVQNAVNLQQFGYPSNSNKLADALTAWCATRYNWEIN
PAWVHDLPDVLKGIEVSINHFTVAGSAIILPTPAYMPFYDVLEVTGRKINQVPMIFEDGRYSFDLVAIEEAFANGAGGLI
VCNPYNPLGATFTAEELQSLAQLAQKYEARIISDEIHAPLTLDEAHIPTASVSDTAAEVTITITATSKGWNTPGLKCAQL
ILHNERDEKTWKKINSLRSHGASTLGIAASIGAYEKGGEWLDTEIEYLRKNRQFLLDNLGQAIPGIGFNKPQATYLAWLD
FSEVEGLNDQDPAAYLLEHARVALNPGLPFGPGGENHARLNFGTSQEILEEFLDRTRTAFSSSPTKNEFIYL

Specific function: Acts As A Beta-Cystathionase And As A Repressor Of The Maltose Regulon. [C]

COG id: COG1168

COG function: function code E; Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. MalY/PatB cystathionine beta-lyase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787909, Length=355, Percent_Identity=29.5774647887324, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1788722, Length=383, Percent_Identity=22.7154046997389, Blast_Score=89, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17567663, Length=296, Percent_Identity=26.3513513513513, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=307, Percent_Identity=23.4527687296417, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =4.4.1.8 [H]

Molecular weight: Translated: 43385; Mature: 43385

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNTLSLEQLRQRGTLKWTTFDQDVLPLWVAETDFDTCPAVVESVQNAVNLQQFGYPSNS
CCCCCCHHHHHHCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCC
NKLADALTAWCATRYNWEINPAWVHDLPDVLKGIEVSINHFTVAGSAIILPTPAYMPFYD
CHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEEEEEEECCEEEECCCCCCCHHH
VLEVTGRKINQVPMIFEDGRYSFDLVAIEEAFANGAGGLIVCNPYNPLGATFTAEELQSL
HHHHCCCCCCCCCEEEECCCEEEEEEEEEHHHCCCCCCEEEECCCCCCCCCCCHHHHHHH
AQLAQKYEARIISDEIHAPLTLDEAHIPTASVSDTAAEVTITITATSKGWNTPGLKCAQL
HHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHH
ILHNERDEKTWKKINSLRSHGASTLGIAASIGAYEKGGEWLDTEIEYLRKNRQFLLDNLG
HHCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QAIPGIGFNKPQATYLAWLDFSEVEGLNDQDPAAYLLEHARVALNPGLPFGPGGENHARL
HHCCCCCCCCCCCEEEEEEEHHHHCCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCEEE
NFGTSQEILEEFLDRTRTAFSSSPTKNEFIYL
ECCCHHHHHHHHHHHHHHHHCCCCCCCCEEEC
>Mature Secondary Structure
MFNTLSLEQLRQRGTLKWTTFDQDVLPLWVAETDFDTCPAVVESVQNAVNLQQFGYPSNS
CCCCCCHHHHHHCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCC
NKLADALTAWCATRYNWEINPAWVHDLPDVLKGIEVSINHFTVAGSAIILPTPAYMPFYD
CHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEEEEEEECCEEEECCCCCCCHHH
VLEVTGRKINQVPMIFEDGRYSFDLVAIEEAFANGAGGLIVCNPYNPLGATFTAEELQSL
HHHHCCCCCCCCCEEEECCCEEEEEEEEEHHHCCCCCCEEEECCCCCCCCCCCHHHHHHH
AQLAQKYEARIISDEIHAPLTLDEAHIPTASVSDTAAEVTITITATSKGWNTPGLKCAQL
HHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCHHHHHH
ILHNERDEKTWKKINSLRSHGASTLGIAASIGAYEKGGEWLDTEIEYLRKNRQFLLDNLG
HHCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QAIPGIGFNKPQATYLAWLDFSEVEGLNDQDPAAYLLEHARVALNPGLPFGPGGENHARL
HHCCCCCCCCCCCEEEEEEEHHHHCCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCCEEE
NFGTSQEILEEFLDRTRTAFSSSPTKNEFIYL
ECCCHHHHHHHHHHHHHHHHCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]