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The map label for this gene is dasR [H]

Identifier: 145296882

GI number: 145296882

Start: 3089251

End: 3090051

Strand: Direct

Name: dasR [H]

Synonym: cgR_2782

Alternate gene names: 145296882

Gene position: 3089251-3090051 (Clockwise)

Preceding gene: 145296877

Following gene: 145296883

Centisome position: 93.21

GC content: 57.3

Gene sequence:

>801_bases
ATGCCTGACCAACCGCTCAACCAGGACGGATTCCCTACCGCATCCAAAGGGGTGGAACCCGACAACCTCCCCGACCGCGT
TCTCGTGGACGGCCTTAAACCAAAGCATCAGCAGCTTCGTGAAATTTTGGAGGAAATCTGCACCACCCAGCTTCAGCCTG
GGGACATGCTGCCTGGTGAGCGCATCCTGGAAGAAAAGTATGGCGTCAGCCGAATTACGGTTCGTCGGGCGATTGGTGAT
CTGGTCGCGTCCGGCAGGTTGAAGCGAGCTCGCGGCAAAGGTACCTTCGTGGCCCACTCGCCGTTGATTTCCCGCCTGCA
TTTGGCCTCGTTTTCCGCAGAGATGGCCGCCCAGAATCTATCGGCTACCAGCAGGATTTTGAGTTCTTCCCGCGGTCCCG
CCCCAGATGATATTGCTGATTTCTTTGGTACCGATCGCGCGGCCCAGCACATCACGTTGCGCCGCCTGCGCCTTGGAAAT
GGTCGACCCTATGCCATTGACAACGGCTGGTATAACTCCGAATTCGCACCTGACCTGCTGGAAAATGATGTGTACAACTC
CGTGTACTCCATCCTGGACCGCGTCTATGGCGTCCCCGTCACCCAGGCCGAGCAAACGGTCACCGCCGTAGCAGCCGATG
AAGACACCGCACGGCTTCTCGACGTCACCCCCGGCGCCCCACTCCTTCGTATCCTTCGACAGTCACTTTCTGGCGATAAG
CCCGTGGAATGGTGCGTTTCCTTGTACCGAACCGACCGATATTCTTTAAAAACATTGGTTACACGCTCCGAAGATCTCTG
A

Upstream 100 bases:

>100_bases
TATCTGTTTTCCAGCCTTGCTTTTTACTAGGCGCTCCTGTCCCGCTTCAGTCACCAAAACCACACCCCTGGTTATGACCA
GATCGGCTAAAATGAACACC

Downstream 100 bases:

>100_bases
CGTGAACCCATTTTGGTGGCATGATGGTGTCAATTATGAGTACAAACTTTGACACTTCGACGTCTCCAGAGGGTGAAACC
AAGAAGAACTCTTCTTTCCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MPDQPLNQDGFPTASKGVEPDNLPDRVLVDGLKPKHQQLREILEEICTTQLQPGDMLPGERILEEKYGVSRITVRRAIGD
LVASGRLKRARGKGTFVAHSPLISRLHLASFSAEMAAQNLSATSRILSSSRGPAPDDIADFFGTDRAAQHITLRRLRLGN
GRPYAIDNGWYNSEFAPDLLENDVYNSVYSILDRVYGVPVTQAEQTVTAVAADEDTARLLDVTPGAPLLRILRQSLSGDK
PVEWCVSLYRTDRYSLKTLVTRSEDL

Sequences:

>Translated_266_residues
MPDQPLNQDGFPTASKGVEPDNLPDRVLVDGLKPKHQQLREILEEICTTQLQPGDMLPGERILEEKYGVSRITVRRAIGD
LVASGRLKRARGKGTFVAHSPLISRLHLASFSAEMAAQNLSATSRILSSSRGPAPDDIADFFGTDRAAQHITLRRLRLGN
GRPYAIDNGWYNSEFAPDLLENDVYNSVYSILDRVYGVPVTQAEQTVTAVAADEDTARLLDVTPGAPLLRILRQSLSGDK
PVEWCVSLYRTDRYSLKTLVTRSEDL
>Mature_265_residues
PDQPLNQDGFPTASKGVEPDNLPDRVLVDGLKPKHQQLREILEEICTTQLQPGDMLPGERILEEKYGVSRITVRRAIGDL
VASGRLKRARGKGTFVAHSPLISRLHLASFSAEMAAQNLSATSRILSSSRGPAPDDIADFFGTDRAAQHITLRRLRLGNG
RPYAIDNGWYNSEFAPDLLENDVYNSVYSILDRVYGVPVTQAEQTVTAVAADEDTARLLDVTPGAPLLRILRQSLSGDKP
VEWCVSLYRTDRYSLKTLVTRSEDL

Specific function: Global regulator that is part of the nutrient-sensing system. In the absence of N-acetylglucosamine 6-P, represses the phosphotransferase system (PTS) specific for the uptake of N- acetylglucosamine (PTSNag), and genes involved in the metabolism of chitin

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=236, Percent_Identity=27.5423728813559, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082252, Length=223, Percent_Identity=29.1479820627803, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790540, Length=222, Percent_Identity=30.6306306306306, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790118, Length=189, Percent_Identity=29.6296296296296, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788418, Length=235, Percent_Identity=23.8297872340426, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 29413; Mature: 29281

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDQPLNQDGFPTASKGVEPDNLPDRVLVDGLKPKHQQLREILEEICTTQLQPGDMLPGE
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHH
RILEEKYGVSRITVRRAIGDLVASGRLKRARGKGTFVAHSPLISRLHLASFSAEMAAQNL
HHHHHHHCHHHHHHHHHHHHHHHHCCHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHH
SATSRILSSSRGPAPDDIADFFGTDRAAQHITLRRLRLGNGRPYAIDNGWYNSEFAPDLL
HHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHH
ENDVYNSVYSILDRVYGVPVTQAEQTVTAVAADEDTARLLDVTPGAPLLRILRQSLSGDK
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHEECCCCCHHEEECCCCCHHHHHHHHHHCCCC
PVEWCVSLYRTDRYSLKTLVTRSEDL
HHHHHHHHHHCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
PDQPLNQDGFPTASKGVEPDNLPDRVLVDGLKPKHQQLREILEEICTTQLQPGDMLPGE
CCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHH
RILEEKYGVSRITVRRAIGDLVASGRLKRARGKGTFVAHSPLISRLHLASFSAEMAAQNL
HHHHHHHCHHHHHHHHHHHHHHHHCCHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHH
SATSRILSSSRGPAPDDIADFFGTDRAAQHITLRRLRLGNGRPYAIDNGWYNSEFAPDLL
HHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHH
ENDVYNSVYSILDRVYGVPVTQAEQTVTAVAADEDTARLLDVTPGAPLLRILRQSLSGDK
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHEECCCCCHHEEECCCCCHHHHHHHHHHCCCC
PVEWCVSLYRTDRYSLKTLVTRSEDL
HHHHHHHHHHCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]