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The map label for this gene is aspC [H]

Identifier: 145296832

GI number: 145296832

Start: 3026095

End: 3027408

Strand: Direct

Name: aspC [H]

Synonym: cgR_2734

Alternate gene names: 145296832

Gene position: 3026095-3027408 (Clockwise)

Preceding gene: 145296831

Following gene: 145296833

Centisome position: 91.31

GC content: 55.02

Gene sequence:

>1314_bases
GTGACTACAGACAAGCGCAAAACCTCTAAGACCACCGACACCGCCAACAAGGCTGTGGGCGCGGATCAGGCGGCGCGTCC
CACTCGGCGAACAACTCGCCGCATCTTCGATCAGTCGGAGAAGATGAAGGACGTGCTGTACGAGATCCGTGGCCCGGTGG
CCGCGGAGGCGGAACGCATGGAGCTCGACGGACACAACATCCTGAAGCTCAACACTGGAAACCCAGCTGTATTCGGATTC
GATGCACCTGACGTGATCATGCGAGACATGATCGCAAACCTCCCAACTTCCCAAGGTTATTCCACCTCAAAGGGCATCAT
TCCAGCCCGCCGAGCAGTGGTAACCCGCTACGAAGTTGTGCCCGGATTCCCCCACTTCGATGTTGATGATGTGTTCTTAG
GCAACGGTGTCTCAGAACTAATCACCATGACCACCCAAGCACTCCTCAACGACGGCGATGAAGTTCTTATCCCAGCACCG
GACTACCCACTGTGGACTGCCGCAACCTCCCTGGCTGGTGGTAAGCCTGTGCACTACCTCTGTGATGAGGAAGATGACTG
GAACCCATCCATCGAAGACATCAAGTCCAAAATCTCAGACAAAACCAAAGCTATTGTGGTGATCAACCCCAACAACCCCA
CGGGAGCTGTCTACCCGCGCCGGGTGTTGGAACAAATCGTCGAGATTGCACGCGAGCATGACCTGCTGATTTTAGCCGAT
GAAATCTACGACCGCATCCTCTACGATGATGCCGAGCACATCAGCCTGGCAACCCTTGCACCAGATCTCCTTTGCATCAC
ATACAACGGTCTATCCAAGGCATACCGCGTCGCAGGATACCGAGCTGGCTGGATGGTATTGACTGGACCAAAGCAATACG
CACGTGGATTTATTGAGGGCCTCGAACTCCTCGCAGGCACTCGACTCTGCCCGAATGTCCCAGCTCAGCACGCTATTCAG
GTGGCTCTCGGTGGACGCCAGTCCATTTACGACCTCACTGGTGAACACGGCCGACTCCTGGAACAGCGCAACATGGCATG
GACGAAACTCAACGAAATCCCAGGTGTCAGCTGTGTGAAACCAATGGGTGCTTTGTACGCGTTCCCCAAGCTTGACCCGA
ACGTGTACGAAATCCACGACGACACCCAACTCATGCTGGATCTTCTCCGTGCCGAGAAAATCCTCATGGTTCAGGGCACT
GGCTTCAACTGGCCACATCACGATCACTTCCGAGTGGTCACCCTGCCATGGGCATCGCAATTAGAAAACGCAATTGAGCG
CCTAGGAAACTTCCTGTCCACCTACAAGCAGTAG

Upstream 100 bases:

>100_bases
TAAGAGAGAACTACACCCTTTTGCCCCTTTTCTGCCTACAAATAGGAATTATTCAACCAATAGCTTTTAACTACGGACAC
AAAGTGGCAACATTGAGCGG

Downstream 100 bases:

>100_bases
CAGTTGTTAGGATTCACCACGAATCTCAGGATTTTTGAGATTCGTGGTGAATTTTTGCGTTTTCCAGTCAGGCTCTTGCA
ACTTTCGGACCGATTTCAGA

Product: aminotransferase AlaT

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTTDKRKTSKTTDTANKAVGADQAARPTRRTTRRIFDQSEKMKDVLYEIRGPVAAEAERMELDGHNILKLNTGNPAVFGF
DAPDVIMRDMIANLPTSQGYSTSKGIIPARRAVVTRYEVVPGFPHFDVDDVFLGNGVSELITMTTQALLNDGDEVLIPAP
DYPLWTAATSLAGGKPVHYLCDEEDDWNPSIEDIKSKISDKTKAIVVINPNNPTGAVYPRRVLEQIVEIAREHDLLILAD
EIYDRILYDDAEHISLATLAPDLLCITYNGLSKAYRVAGYRAGWMVLTGPKQYARGFIEGLELLAGTRLCPNVPAQHAIQ
VALGGRQSIYDLTGEHGRLLEQRNMAWTKLNEIPGVSCVKPMGALYAFPKLDPNVYEIHDDTQLMLDLLRAEKILMVQGT
GFNWPHHDHFRVVTLPWASQLENAIERLGNFLSTYKQ

Sequences:

>Translated_437_residues
MTTDKRKTSKTTDTANKAVGADQAARPTRRTTRRIFDQSEKMKDVLYEIRGPVAAEAERMELDGHNILKLNTGNPAVFGF
DAPDVIMRDMIANLPTSQGYSTSKGIIPARRAVVTRYEVVPGFPHFDVDDVFLGNGVSELITMTTQALLNDGDEVLIPAP
DYPLWTAATSLAGGKPVHYLCDEEDDWNPSIEDIKSKISDKTKAIVVINPNNPTGAVYPRRVLEQIVEIAREHDLLILAD
EIYDRILYDDAEHISLATLAPDLLCITYNGLSKAYRVAGYRAGWMVLTGPKQYARGFIEGLELLAGTRLCPNVPAQHAIQ
VALGGRQSIYDLTGEHGRLLEQRNMAWTKLNEIPGVSCVKPMGALYAFPKLDPNVYEIHDDTQLMLDLLRAEKILMVQGT
GFNWPHHDHFRVVTLPWASQLENAIERLGNFLSTYKQ
>Mature_436_residues
TTDKRKTSKTTDTANKAVGADQAARPTRRTTRRIFDQSEKMKDVLYEIRGPVAAEAERMELDGHNILKLNTGNPAVFGFD
APDVIMRDMIANLPTSQGYSTSKGIIPARRAVVTRYEVVPGFPHFDVDDVFLGNGVSELITMTTQALLNDGDEVLIPAPD
YPLWTAATSLAGGKPVHYLCDEEDDWNPSIEDIKSKISDKTKAIVVINPNNPTGAVYPRRVLEQIVEIAREHDLLILADE
IYDRILYDDAEHISLATLAPDLLCITYNGLSKAYRVAGYRAGWMVLTGPKQYARGFIEGLELLAGTRLCPNVPAQHAIQV
ALGGRQSIYDLTGEHGRLLEQRNMAWTKLNEIPGVSCVKPMGALYAFPKLDPNVYEIHDDTQLMLDLLRAEKILMVQGTG
FNWPHHDHFRVVTLPWASQLENAIERLGNFLSTYKQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=489, Percent_Identity=25.7668711656442, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI215599424, Length=376, Percent_Identity=27.3936170212766, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI4507369, Length=406, Percent_Identity=26.6009852216749, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI4885351, Length=451, Percent_Identity=26.1640798226164, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI95147551, Length=237, Percent_Identity=25.7383966244726, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI169881279, Length=237, Percent_Identity=25.7383966244726, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI56713254, Length=158, Percent_Identity=32.9113924050633, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI56713256, Length=163, Percent_Identity=31.9018404907975, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI169881281, Length=148, Percent_Identity=29.7297297297297, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI1788627, Length=402, Percent_Identity=61.9402985074627, Blast_Score=536, Evalue=1e-154,
Organism=Escherichia coli, GI1788722, Length=408, Percent_Identity=26.2254901960784, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786816, Length=238, Percent_Identity=23.109243697479, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17567663, Length=421, Percent_Identity=29.2161520190024, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71981209, Length=469, Percent_Identity=23.454157782516, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=221, Percent_Identity=32.579185520362, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71994476, Length=221, Percent_Identity=32.579185520362, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17567369, Length=172, Percent_Identity=30.2325581395349, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71981215, Length=294, Percent_Identity=23.469387755102, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323118, Length=361, Percent_Identity=29.0858725761773, Blast_Score=126, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6320317, Length=412, Percent_Identity=27.1844660194175, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6322401, Length=238, Percent_Identity=24.7899159663866, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI18859735, Length=373, Percent_Identity=27.3458445040214, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI45551451, Length=402, Percent_Identity=27.6119402985075, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24641770, Length=402, Percent_Identity=27.6119402985075, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24641760, Length=402, Percent_Identity=27.6119402985075, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24641768, Length=402, Percent_Identity=27.6119402985075, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24641766, Length=402, Percent_Identity=27.6119402985075, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24641764, Length=402, Percent_Identity=27.6119402985075, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28573069, Length=296, Percent_Identity=25.6756756756757, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24646114, Length=296, Percent_Identity=25.6756756756757, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28573067, Length=296, Percent_Identity=25.6756756756757, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28573065, Length=296, Percent_Identity=25.6756756756757, Blast_Score=94, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 48684; Mature: 48553

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDKRKTSKTTDTANKAVGADQAARPTRRTTRRIFDQSEKMKDVLYEIRGPVAAEAERM
CCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHE
ELDGHNILKLNTGNPAVFGFDAPDVIMRDMIANLPTSQGYSTSKGIIPARRAVVTRYEVV
ECCCCCEEEEECCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCC
PGFPHFDVDDVFLGNGVSELITMTTQALLNDGDEVLIPAPDYPLWTAATSLAGGKPVHYL
CCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCEEEE
CDEEDDWNPSIEDIKSKISDKTKAIVVINPNNPTGAVYPRRVLEQIVEIAREHDLLILAD
CCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEHH
EIYDRILYDDAEHISLATLAPDLLCITYNGLSKAYRVAGYRAGWMVLTGPKQYARGFIEG
HHHHHHHHCCHHHEEEHHHCCCEEEEEECCHHHHHHHHCCCCCEEEEECCHHHHHHHHHH
LELLAGTRLCPNVPAQHAIQVALGGRQSIYDLTGEHGRLLEQRNMAWTKLNEIPGVSCVK
HHHHHCCCCCCCCCHHHEEEEEECCCCHHHHCCCCHHHHHHHCCCHHHHHHCCCCCHHHH
PMGALYAFPKLDPNVYEIHDDTQLMLDLLRAEKILMVQGTGFNWPHHDHFRVVTLPWASQ
HHHHHHCCCCCCCCEEEECCCHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEEECCHHH
LENAIERLGNFLSTYKQ
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTDKRKTSKTTDTANKAVGADQAARPTRRTTRRIFDQSEKMKDVLYEIRGPVAAEAERM
CCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHE
ELDGHNILKLNTGNPAVFGFDAPDVIMRDMIANLPTSQGYSTSKGIIPARRAVVTRYEVV
ECCCCCEEEEECCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCC
PGFPHFDVDDVFLGNGVSELITMTTQALLNDGDEVLIPAPDYPLWTAATSLAGGKPVHYL
CCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCEEEE
CDEEDDWNPSIEDIKSKISDKTKAIVVINPNNPTGAVYPRRVLEQIVEIAREHDLLILAD
CCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEHH
EIYDRILYDDAEHISLATLAPDLLCITYNGLSKAYRVAGYRAGWMVLTGPKQYARGFIEG
HHHHHHHHCCHHHEEEHHHCCCEEEEEECCHHHHHHHHCCCCCEEEEECCHHHHHHHHHH
LELLAGTRLCPNVPAQHAIQVALGGRQSIYDLTGEHGRLLEQRNMAWTKLNEIPGVSCVK
HHHHHCCCCCCCCCHHHEEEEEECCCCHHHHCCCCHHHHHHHCCCHHHHHHCCCCCHHHH
PMGALYAFPKLDPNVYEIHDDTQLMLDLLRAEKILMVQGTGFNWPHHDHFRVVTLPWASQ
HHHHHHCCCCCCCCEEEECCCHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEEECCHHH
LENAIERLGNFLSTYKQ
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]