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The map label for this gene is fprA [H]

Identifier: 145296801

GI number: 145296801

Start: 2995740

End: 2997113

Strand: Direct

Name: fprA [H]

Synonym: cgR_2704

Alternate gene names: 145296801

Gene position: 2995740-2997113 (Clockwise)

Preceding gene: 145296789

Following gene: 145296802

Centisome position: 90.39

GC content: 57.5

Gene sequence:

>1374_bases
ATGACAACTCCCCTGCGCGTAGCCGTCATCGGAGCTGGCCCTGCTGGCATTTACGCATCCGACCTCCTCATCCGCAATGA
AGAGCGCGAAGTGTTCGTTGACCTTTTCGAGCAAATGCCTGCACCGTTCGGACTCATCCGTTACGGCGTTGCTCCAGACC
ACCCACGCATCAAGGGCATCGTTAAGTCCCTGCACAACGTGTTGGACAAGCCACGCCTGCGCCTGCTCGGCAACATTGAA
ATCGGCAAAGACATCACCGTCGAAGAACTCCGCGACTACTACGATGCAGTCGTGTTCTCCACCGGCGCAGTTGCAGACCG
CGACCTCAACATCCCCGGAATTGAAGCAGAAGGCTCCTTCGGTGCCGGCGAGTTCGTGGGCTTCTACGACGGCAACCCAC
GCTTCGAGCGCTCCTGGGATCTGTCTGCACAGTCCGTCGCTGTTATCGGCGTTGGTAACGTCGGCCTCGACGTAGCCCGC
ATCCTGGCTAAGACAGGCGACGAGCTCAAAGTCACCGAAATTTCCGACAACGTCTACGACTCCCTCAAAGAAAACAAGGC
CACTGAAGTACACGTTTTCGGACGTCGTGGCCCAGCACAGGTCAAGTTCACCCCACAGGAACTCAAAGAACTCGACCACT
CCCCCACCATCAACGTGGTTGTTGACCCAGAAGACATCGACTACGACGGCGCCTCCGAAGAAGCCCGACGCGCATCCAAG
TCCCAGGACCTGGTCTGCCAGATCCTGGAACAGTACGCAATCCGCGAGCCAAAGGATGCTCCACACACCCTGCAGATCCA
CCTCTTTGAAAACCCAGTTGAGGTTCTTCAAAAGGACGGCAAAGTTGTTGGCCTGCGCACCGAACGCACCGCACTCGACG
GCAACGGTGGCGTAAACGGAACCGGAGAATTCAAGGACTGGCCAGTCCAGGCTGTTTACCGCGCAGTCGGCTACAAGTCC
GACCCAATTGATGGCGTCCCATTCGATGATGCCAAGCACGTCATCCCTAATGACGGCGGACATGTCCTCACCGCTCCAGG
TGCAGAACCAGTACCAGGCCTCTATGCAACCGGCTGGATCAAGCGTGGACCAATCGGTCTGATCGGCAACACCAAGTCTG
ATGCCAAGGAAACCACCGACATCCTCATCAAGGATGCCGTCGCCGGTGTACTTGAAGCTCCAAAGCACCAGGGCGAAGAA
GCCATCATTGAGCTTCTCGATTCCCGCAACATCCCATTCACCACCTGGGAAGGCTGGTACAAACTCGACGCAGCAGAGCG
CGCACTCGGTGAAGCCGAAGGCCGCGAGCGTAAGAAGATTGTTGATTGGGAAGAGATGGTCCGCCAGGCCCGCGAAGCCC
CAGCAATTGTCTAA

Upstream 100 bases:

>100_bases
TCTAGGAGAGTTAAACAACCTGGACTTGAAACACCTTTAACTACTTGATTTTCACACCCTTGTTTCCATAAAAGGGCTCA
CGAAAGGCAACTTCAAACAC

Downstream 100 bases:

>100_bases
ATTGTTTTAGCGCGTTTGAGAAGTCCCCACCCGATTTATTCGAGGCGGGGACTTTCGCTTTCCACCTTGCGCGGCCGATT
CACCATATAAACCAGCACTG

Product: hypothetical protein

Products: NA

Alternate protein names: NFR [H]

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MTTPLRVAVIGAGPAGIYASDLLIRNEEREVFVDLFEQMPAPFGLIRYGVAPDHPRIKGIVKSLHNVLDKPRLRLLGNIE
IGKDITVEELRDYYDAVVFSTGAVADRDLNIPGIEAEGSFGAGEFVGFYDGNPRFERSWDLSAQSVAVIGVGNVGLDVAR
ILAKTGDELKVTEISDNVYDSLKENKATEVHVFGRRGPAQVKFTPQELKELDHSPTINVVVDPEDIDYDGASEEARRASK
SQDLVCQILEQYAIREPKDAPHTLQIHLFENPVEVLQKDGKVVGLRTERTALDGNGGVNGTGEFKDWPVQAVYRAVGYKS
DPIDGVPFDDAKHVIPNDGGHVLTAPGAEPVPGLYATGWIKRGPIGLIGNTKSDAKETTDILIKDAVAGVLEAPKHQGEE
AIIELLDSRNIPFTTWEGWYKLDAAERALGEAEGRERKKIVDWEEMVRQAREAPAIV

Sequences:

>Translated_457_residues
MTTPLRVAVIGAGPAGIYASDLLIRNEEREVFVDLFEQMPAPFGLIRYGVAPDHPRIKGIVKSLHNVLDKPRLRLLGNIE
IGKDITVEELRDYYDAVVFSTGAVADRDLNIPGIEAEGSFGAGEFVGFYDGNPRFERSWDLSAQSVAVIGVGNVGLDVAR
ILAKTGDELKVTEISDNVYDSLKENKATEVHVFGRRGPAQVKFTPQELKELDHSPTINVVVDPEDIDYDGASEEARRASK
SQDLVCQILEQYAIREPKDAPHTLQIHLFENPVEVLQKDGKVVGLRTERTALDGNGGVNGTGEFKDWPVQAVYRAVGYKS
DPIDGVPFDDAKHVIPNDGGHVLTAPGAEPVPGLYATGWIKRGPIGLIGNTKSDAKETTDILIKDAVAGVLEAPKHQGEE
AIIELLDSRNIPFTTWEGWYKLDAAERALGEAEGRERKKIVDWEEMVRQAREAPAIV
>Mature_456_residues
TTPLRVAVIGAGPAGIYASDLLIRNEEREVFVDLFEQMPAPFGLIRYGVAPDHPRIKGIVKSLHNVLDKPRLRLLGNIEI
GKDITVEELRDYYDAVVFSTGAVADRDLNIPGIEAEGSFGAGEFVGFYDGNPRFERSWDLSAQSVAVIGVGNVGLDVARI
LAKTGDELKVTEISDNVYDSLKENKATEVHVFGRRGPAQVKFTPQELKELDHSPTINVVVDPEDIDYDGASEEARRASKS
QDLVCQILEQYAIREPKDAPHTLQIHLFENPVEVLQKDGKVVGLRTERTALDGNGGVNGTGEFKDWPVQAVYRAVGYKSD
PIDGVPFDDAKHVIPNDGGHVLTAPGAEPVPGLYATGWIKRGPIGLIGNTKSDAKETTDILIKDAVAGVLEAPKHQGEEA
IIELLDSRNIPFTTWEGWYKLDAAERALGEAEGRERKKIVDWEEMVRQAREAPAIV

Specific function: May serve as electron transfer protein and supply electrons to P450 systems [H]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=458, Percent_Identity=38.2096069868996, Blast_Score=296, Evalue=2e-80,
Organism=Homo sapiens, GI111118983, Length=464, Percent_Identity=37.7155172413793, Blast_Score=291, Evalue=7e-79,
Organism=Escherichia coli, GI87082180, Length=161, Percent_Identity=31.055900621118, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788811, Length=170, Percent_Identity=27.6470588235294, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789606, Length=172, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17543860, Length=458, Percent_Identity=30.5676855895196, Blast_Score=236, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17570289, Length=126, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320584, Length=480, Percent_Identity=30.4166666666667, Blast_Score=198, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6320030, Length=163, Percent_Identity=31.2883435582822, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI17137178, Length=463, Percent_Identity=33.9092872570194, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24665547, Length=175, Percent_Identity=31.4285714285714, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24665543, Length=175, Percent_Identity=31.4285714285714, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574881, Length=172, Percent_Identity=31.3953488372093, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24665539, Length=172, Percent_Identity=31.3953488372093, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 50057; Mature: 49926

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPLRVAVIGAGPAGIYASDLLIRNEEREVFVDLFEQMPAPFGLIRYGVAPDHPRIKGI
CCCCEEEEEEECCCCCHHHHHEEEECCCHHHHHHHHHHCCCCHHEEEECCCCCCHHHHHH
VKSLHNVLDKPRLRLLGNIEIGKDITVEELRDYYDAVVFSTGAVADRDLNIPGIEAEGSF
HHHHHHHHCCCCEEEEECEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
GAGEFVGFYDGNPRFERSWDLSAQSVAVIGVGNVGLDVARILAKTGDELKVTEISDNVYD
CCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEECCHHHHH
SLKENKATEVHVFGRRGPAQVKFTPQELKELDHSPTINVVVDPEDIDYDGASEEARRASK
HHHHCCCCEEEEECCCCCCEEEECHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHCC
SQDLVCQILEQYAIREPKDAPHTLQIHLFENPVEVLQKDGKVVGLRTERTALDGNGGVNG
CHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHCCCCEEEEEECCEEECCCCCCCC
TGEFKDWPVQAVYRAVGYKSDPIDGVPFDDAKHVIPNDGGHVLTAPGAEPVPGLYATGWI
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCC
KRGPIGLIGNTKSDAKETTDILIKDAVAGVLEAPKHQGEEAIIELLDSRNIPFTTWEGWY
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEECCCEE
KLDAAERALGEAEGRERKKIVDWEEMVRQAREAPAIV
EECHHHHHHHHHCCCHHHCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTPLRVAVIGAGPAGIYASDLLIRNEEREVFVDLFEQMPAPFGLIRYGVAPDHPRIKGI
CCCEEEEEEECCCCCHHHHHEEEECCCHHHHHHHHHHCCCCHHEEEECCCCCCHHHHHH
VKSLHNVLDKPRLRLLGNIEIGKDITVEELRDYYDAVVFSTGAVADRDLNIPGIEAEGSF
HHHHHHHHCCCCEEEEECEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
GAGEFVGFYDGNPRFERSWDLSAQSVAVIGVGNVGLDVARILAKTGDELKVTEISDNVYD
CCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEECCHHHHH
SLKENKATEVHVFGRRGPAQVKFTPQELKELDHSPTINVVVDPEDIDYDGASEEARRASK
HHHHCCCCEEEEECCCCCCEEEECHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHCC
SQDLVCQILEQYAIREPKDAPHTLQIHLFENPVEVLQKDGKVVGLRTERTALDGNGGVNG
CHHHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHCCCCEEEEEECCEEECCCCCCCC
TGEFKDWPVQAVYRAVGYKSDPIDGVPFDDAKHVIPNDGGHVLTAPGAEPVPGLYATGWI
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCC
KRGPIGLIGNTKSDAKETTDILIKDAVAGVLEAPKHQGEEAIIELLDSRNIPFTTWEGWY
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEECCCEE
KLDAAERALGEAEGRERKKIVDWEEMVRQAREAPAIV
EECHHHHHHHHHCCCHHHCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12071965; 12614197; 12102623 [H]