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The map label for this gene is bglC [H]

Identifier: 145296704

GI number: 145296704

Start: 2878401

End: 2879819

Strand: Reverse

Name: bglC [H]

Synonym: cgR_2609

Alternate gene names: 145296704

Gene position: 2879819-2878401 (Counterclockwise)

Preceding gene: 145296705

Following gene: 145296703

Centisome position: 86.89

GC content: 50.18

Gene sequence:

>1419_bases
ATGCACATTTCTAAACTCCCTCCATTCCCAGAAAATTTTCTGTGGGGAGCATCCACCTCTGCGTACCAAACTGAAGGTGC
GTGGAATGAAGATGGCAAGGGACCTTCAGTGATAGATGTTCGCGAAAGCTACCCGGAAGGTACCTGCGATTACACCGTGG
CAACCGATACCTACCACCACGTGGAAGAAGACGTTGCACTGTTCGCAGAATTGGGTCTTAAAACTTACCGTTTCTCTATC
GCGTGGACCCGAATTATTCCGGATGGCGATGGTGAGGAAAATCCTGCGGGTATCGCCTTTTACCACCGCCTCATTGATGA
GTTGCTGAAATACGGCATTGAACCACTGGTGACCATGTACCACTTTGATCTTCCAGCAGAATTGGATAACAAGGGTGGTT
GGGGAAGCCGCGACACTATCGATGCTTTTGAGCGTTTCGCAAAGATTTTGTTCCGAGAATATGGATCAAAGGTAAAGCGC
TGGCTGACCATCAATGAGCAGAACATGATGATCTTGCACGGTGATGCTCTGGGCACCACCAAGCTTCGTGGTTTGGAGGC
CAAGAAGGATCTCTACCAGCAGAATCACAATATGTTTGTGGCTCAGGCCAAAGCGATGATTGCCTGCCATGAGATGTTGG
ATGATGCTCTGATTGGACCTGCCCCCAACATTGCTCCTGTGTACGCAGCAACTGAAGCTCCACAAGATGTGGTGACTGCT
GATAACTGGTGGGCGATCCGCAACTGGCTGTACCTGGATTTGGCTGTTCGCGGTGAATACAACGGTATCGCCTGGGCATA
CCTGACTGAGCGCGGTTGGGAACCCACAATTGAAGACGGCGACATGGAAATCATGAAGGCCGCTAAGCCCGACTTCATTG
CTTTTAATTACTACAACTCTCAAACCGTGGCTGCGATTGAAGAAGGCGAAGAAATCAATGATGGCAGTGGCGACCAGCAG
ATCGCCTGGGGTGAGCAGGGCCTGTACAAGGCAGTAAAGAACACTCACCTGGAGATCACCAACTTCGGATGGGGCATTGA
TCCACATGGTTTCCGCACCGTCATGCGCCAGATTTGGTACCGCTACCGTTTGCCCATGATTCTGACGGAAAACGGTTTGG
GTGAATTCGACACTTTGACTGAGGACGGCCGCGTTCATGATGATTACCGCATTGAATATTTGGCCAAGCACATTGAACAG
ATCCAATATGCTCTTGCAGAGGGCGTTGAAATGTTTGGTTACTGCCCGTGGTCGGCTATTGATTTGGTGTCGACCCACCA
GGGTGTGGCCAAGCGTTACGGATTCATTTATGTTGATCGCACGGATTCGGATCTGAAGTCTTTGGCGCGTATCCGGAAGG
ACTCTTTCTTCTGGTACCAAGGTGTGATCGCTAATAATGCACTAAGTACGCTTGAGTAA

Upstream 100 bases:

>100_bases
ACGCTTAAAACCATCGGATTCCTTCTTCAGCTCTAGGGCTAGGGAGGAATCTTGGTACGAGTCCACATACTTGCATTAAT
ACAGAAAGATTTAGCTAACC

Downstream 100 bases:

>100_bases
GAATAACGAGAGATTATGGTGAGCACTTCTGCTTGGAAGATTATTCAAGTCTTCAACAACAACGTGGTCCTAGCTGAGAA
CGGCTCAGATAGGGCTGTGT

Product: hypothetical protein

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MHISKLPPFPENFLWGASTSAYQTEGAWNEDGKGPSVIDVRESYPEGTCDYTVATDTYHHVEEDVALFAELGLKTYRFSI
AWTRIIPDGDGEENPAGIAFYHRLIDELLKYGIEPLVTMYHFDLPAELDNKGGWGSRDTIDAFERFAKILFREYGSKVKR
WLTINEQNMMILHGDALGTTKLRGLEAKKDLYQQNHNMFVAQAKAMIACHEMLDDALIGPAPNIAPVYAATEAPQDVVTA
DNWWAIRNWLYLDLAVRGEYNGIAWAYLTERGWEPTIEDGDMEIMKAAKPDFIAFNYYNSQTVAAIEEGEEINDGSGDQQ
IAWGEQGLYKAVKNTHLEITNFGWGIDPHGFRTVMRQIWYRYRLPMILTENGLGEFDTLTEDGRVHDDYRIEYLAKHIEQ
IQYALAEGVEMFGYCPWSAIDLVSTHQGVAKRYGFIYVDRTDSDLKSLARIRKDSFFWYQGVIANNALSTLE

Sequences:

>Translated_472_residues
MHISKLPPFPENFLWGASTSAYQTEGAWNEDGKGPSVIDVRESYPEGTCDYTVATDTYHHVEEDVALFAELGLKTYRFSI
AWTRIIPDGDGEENPAGIAFYHRLIDELLKYGIEPLVTMYHFDLPAELDNKGGWGSRDTIDAFERFAKILFREYGSKVKR
WLTINEQNMMILHGDALGTTKLRGLEAKKDLYQQNHNMFVAQAKAMIACHEMLDDALIGPAPNIAPVYAATEAPQDVVTA
DNWWAIRNWLYLDLAVRGEYNGIAWAYLTERGWEPTIEDGDMEIMKAAKPDFIAFNYYNSQTVAAIEEGEEINDGSGDQQ
IAWGEQGLYKAVKNTHLEITNFGWGIDPHGFRTVMRQIWYRYRLPMILTENGLGEFDTLTEDGRVHDDYRIEYLAKHIEQ
IQYALAEGVEMFGYCPWSAIDLVSTHQGVAKRYGFIYVDRTDSDLKSLARIRKDSFFWYQGVIANNALSTLE
>Mature_472_residues
MHISKLPPFPENFLWGASTSAYQTEGAWNEDGKGPSVIDVRESYPEGTCDYTVATDTYHHVEEDVALFAELGLKTYRFSI
AWTRIIPDGDGEENPAGIAFYHRLIDELLKYGIEPLVTMYHFDLPAELDNKGGWGSRDTIDAFERFAKILFREYGSKVKR
WLTINEQNMMILHGDALGTTKLRGLEAKKDLYQQNHNMFVAQAKAMIACHEMLDDALIGPAPNIAPVYAATEAPQDVVTA
DNWWAIRNWLYLDLAVRGEYNGIAWAYLTERGWEPTIEDGDMEIMKAAKPDFIAFNYYNSQTVAAIEEGEEINDGSGDQQ
IAWGEQGLYKAVKNTHLEITNFGWGIDPHGFRTVMRQIWYRYRLPMILTENGLGEFDTLTEDGRVHDDYRIEYLAKHIEQ
IQYALAEGVEMFGYCPWSAIDLVSTHQGVAKRYGFIYVDRTDSDLKSLARIRKDSFFWYQGVIANNALSTLE

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=489, Percent_Identity=30.4703476482618, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI13273313, Length=491, Percent_Identity=29.938900203666, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI110681710, Length=487, Percent_Identity=30.1848049281314, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI24497614, Length=496, Percent_Identity=29.2338709677419, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI28376633, Length=200, Percent_Identity=36.5, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI190360571, Length=87, Percent_Identity=44.8275862068966, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI2367270, Length=480, Percent_Identity=42.0833333333333, Blast_Score=345, Evalue=3e-96,
Organism=Escherichia coli, GI2367174, Length=488, Percent_Identity=37.5, Blast_Score=327, Evalue=8e-91,
Organism=Escherichia coli, GI1789070, Length=488, Percent_Identity=37.7049180327869, Blast_Score=310, Evalue=1e-85,
Organism=Caenorhabditis elegans, GI17552856, Length=476, Percent_Identity=30.2521008403361, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17539390, Length=480, Percent_Identity=28.125, Blast_Score=174, Evalue=6e-44,
Organism=Drosophila melanogaster, GI21356577, Length=478, Percent_Identity=27.6150627615063, Blast_Score=171, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 53823; Mature: 53823

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHISKLPPFPENFLWGASTSAYQTEGAWNEDGKGPSVIDVRESYPEGTCDYTVATDTYHH
CCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEHHHCCCCCCCCEEEECCHHHH
VEEDVALFAELGLKTYRFSIAWTRIIPDGDGEENPAGIAFYHRLIDELLKYGIEPLVTMY
HHHHHHHHHHHCCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
HFDLPAELDNKGGWGSRDTIDAFERFAKILFREYGSKVKRWLTINEQNMMILHGDALGTT
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCCCCH
KLRGLEAKKDLYQQNHNMFVAQAKAMIACHEMLDDALIGPAPNIAPVYAATEAPQDVVTA
HHCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEC
DNWWAIRNWLYLDLAVRGEYNGIAWAYLTERGWEPTIEDGDMEIMKAAKPDFIAFNYYNS
CCCEEEEEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCEEEEEEECC
QTVAAIEEGEEINDGSGDQQIAWGEQGLYKAVKNTHLEITNFGWGIDPHGFRTVMRQIWY
CEEEEECCCCCCCCCCCCCEEECCHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHH
RYRLPMILTENGLGEFDTLTEDGRVHDDYRIEYLAKHIEQIQYALAEGVEMFGYCPWSAI
HHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHH
DLVSTHQGVAKRYGFIYVDRTDSDLKSLARIRKDSFFWYQGVIANNALSTLE
HHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCEEEEEEHHCCHHHHCC
>Mature Secondary Structure
MHISKLPPFPENFLWGASTSAYQTEGAWNEDGKGPSVIDVRESYPEGTCDYTVATDTYHH
CCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEEHHHCCCCCCCCEEEECCHHHH
VEEDVALFAELGLKTYRFSIAWTRIIPDGDGEENPAGIAFYHRLIDELLKYGIEPLVTMY
HHHHHHHHHHHCCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
HFDLPAELDNKGGWGSRDTIDAFERFAKILFREYGSKVKRWLTINEQNMMILHGDALGTT
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCCCCH
KLRGLEAKKDLYQQNHNMFVAQAKAMIACHEMLDDALIGPAPNIAPVYAATEAPQDVVTA
HHCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEC
DNWWAIRNWLYLDLAVRGEYNGIAWAYLTERGWEPTIEDGDMEIMKAAKPDFIAFNYYNS
CCCEEEEEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCEEEEEEECC
QTVAAIEEGEEINDGSGDQQIAWGEQGLYKAVKNTHLEITNFGWGIDPHGFRTVMRQIWY
CEEEEECCCCCCCCCCCCCEEECCHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHH
RYRLPMILTENGLGEFDTLTEDGRVHDDYRIEYLAKHIEQIQYALAEGVEMFGYCPWSAI
HHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHH
DLVSTHQGVAKRYGFIYVDRTDSDLKSLARIRKDSFFWYQGVIANNALSTLE
HHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCEEEEEEHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]