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The map label for this gene is nanE

Identifier: 145296645

GI number: 145296645

Start: 2819805

End: 2820503

Strand: Direct

Name: nanE

Synonym: cgR_2553

Alternate gene names: 145296645

Gene position: 2819805-2820503 (Clockwise)

Preceding gene: 145296644

Following gene: 145296646

Centisome position: 85.08

GC content: 56.8

Gene sequence:

>699_bases
ATGGACTTAAATACTCAACGCTCAAAGCTCTACGCACAGCTTCAAGGCCAGCTCATTGTTTCCGTGCAAGCTCCCGACGG
CCATGCCATGCGAGATACCCATACGCTCACCCATGTGGCCGCAGCCTGTGTCGATGGCGGTGCTCCTGCCATTCGCTGTG
GCGGTTACGGCGGTTTGGAAGATATCCGTTCAATCTCCAACCGTGTCGACGTTCCCGTTTTCGGACTCACCAAAGAAGGC
TCCGAAGGAGTTTACATCACCCCAACCAGGGATTCCGTTCGAGCAGTGGCAGAATCCGGCGCCACTGTAGTCTGCGCGGA
TGCAACTTTCCGACCTAGGCCTGACGGCTCCACCTTTGCAGAGCTGGTCACTGTTGCCCACGATTCCGGAATTCTCATCA
TGGCGGACTGCGCAACTCCCGAAGAAGTTCTCAGTGCGCATAAGGCTGGCGCGGATTTTGTGTCCACCACGCTTGCCGGA
TACACCGAACACCGCGAGAAAACAGTCGGGCCAGATTTCGATTGCCTCCGCGAAGCCCGTGAGTTAGTTCCAGATGCGTT
CCTCATTGGCGAAGGCCGCTTCTCCAACCCTGCGGATGTTGCACACGGTCGTCTCATTGGTGCCAACGCGATCATCGTGG
GCACCGCAATCACTGACCCTGGTTTCATCACTGGACAGTTCGCGTCACTGTTGCACTAG

Upstream 100 bases:

>100_bases
TGGTGCCCAAGCAGCCGTCATCGCAGCAGCAAAATATGCCCGCGATAACGCCTTTTAAGCACCTAAAACGCTGTTCTCAA
CACAGGAGTTTCCTTAAATA

Downstream 100 bases:

>100_bases
CACTTAGTCCAGCGCTGCACGGATCCACCACAAATCGCTCGGATCAGCGGTTTTGTGGTGGATTTTTGCGTCTCATCTGC
CTAAAAGCGCTAGGATCTAC

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MDLNTQRSKLYAQLQGQLIVSVQAPDGHAMRDTHTLTHVAAACVDGGAPAIRCGGYGGLEDIRSISNRVDVPVFGLTKEG
SEGVYITPTRDSVRAVAESGATVVCADATFRPRPDGSTFAELVTVAHDSGILIMADCATPEEVLSAHKAGADFVSTTLAG
YTEHREKTVGPDFDCLREARELVPDAFLIGEGRFSNPADVAHGRLIGANAIIVGTAITDPGFITGQFASLLH

Sequences:

>Translated_232_residues
MDLNTQRSKLYAQLQGQLIVSVQAPDGHAMRDTHTLTHVAAACVDGGAPAIRCGGYGGLEDIRSISNRVDVPVFGLTKEG
SEGVYITPTRDSVRAVAESGATVVCADATFRPRPDGSTFAELVTVAHDSGILIMADCATPEEVLSAHKAGADFVSTTLAG
YTEHREKTVGPDFDCLREARELVPDAFLIGEGRFSNPADVAHGRLIGANAIIVGTAITDPGFITGQFASLLH
>Mature_232_residues
MDLNTQRSKLYAQLQGQLIVSVQAPDGHAMRDTHTLTHVAAACVDGGAPAIRCGGYGGLEDIRSISNRVDVPVFGLTKEG
SEGVYITPTRDSVRAVAESGATVVCADATFRPRPDGSTFAELVTVAHDSGILIMADCATPEEVLSAHKAGADFVSTTLAG
YTEHREKTVGPDFDCLREARELVPDAFLIGEGRFSNPADVAHGRLIGANAIIVGTAITDPGFITGQFASLLH

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential)

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family

Homologues:

Organism=Escherichia coli, GI1789617, Length=217, Percent_Identity=35.9447004608295, Blast_Score=97, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NANE_CORGB (A4QH48)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001139466.1
- ProteinModelPortal:   A4QH48
- SMR:   A4QH48
- STRING:   A4QH48
- GeneID:   4991869
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_2553
- eggNOG:   COG3010
- HOGENOM:   HBG296941
- OMA:   EHIVSWF
- ProtClustDB:   PRK01130
- HAMAP:   MF_01235
- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF04131 NanE; SSF51366 RibP_bind_barrel

EC number: =5.1.3.9

Molecular weight: Translated: 24362; Mature: 24362

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNTQRSKLYAQLQGQLIVSVQAPDGHAMRDTHTLTHVAAACVDGGAPAIRCGGYGGLE
CCCCHHHHHHHHEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHH
DIRSISNRVDVPVFGLTKEGSEGVYITPTRDSVRAVAESGATVVCADATFRPRPDGSTFA
HHHHHHHCCCCCEEEECCCCCCCEEEECCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHH
ELVTVAHDSGILIMADCATPEEVLSAHKAGADFVSTTLAGYTEHREKTVGPDFDCLREAR
HHHHHCCCCCEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ELVPDAFLIGEGRFSNPADVAHGRLIGANAIIVGTAITDPGFITGQFASLLH
HHCCCEEEEECCCCCCCCHHHCCEEEECCEEEEEEEECCCCCCHHHHHHHCC
>Mature Secondary Structure
MDLNTQRSKLYAQLQGQLIVSVQAPDGHAMRDTHTLTHVAAACVDGGAPAIRCGGYGGLE
CCCCHHHHHHHHEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHH
DIRSISNRVDVPVFGLTKEGSEGVYITPTRDSVRAVAESGATVVCADATFRPRPDGSTFA
HHHHHHHCCCCCEEEECCCCCCCEEEECCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHH
ELVTVAHDSGILIMADCATPEEVLSAHKAGADFVSTTLAGYTEHREKTVGPDFDCLREAR
HHHHHCCCCCEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ELVPDAFLIGEGRFSNPADVAHGRLIGANAIIVGTAITDPGFITGQFASLLH
HHCCCEEEEECCCCCCCCHHHCCEEEECCEEEEEEEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA