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The map label for this gene is nagA [H]

Identifier: 145296642

GI number: 145296642

Start: 2816518

End: 2817684

Strand: Reverse

Name: nagA [H]

Synonym: cgR_2550

Alternate gene names: 145296642

Gene position: 2817684-2816518 (Counterclockwise)

Preceding gene: 145296647

Following gene: 145296641

Centisome position: 85.02

GC content: 53.81

Gene sequence:

>1167_bases
ATGGCAGAAGTGGTGCATTATCAAGAAAATGCAGGTCAAGCAGTTAAAAAAATTGAAGGAAGAATTGTTACCCCCCACGG
GGTGATTGATGGCTTTCTCCAACTCGAAAACGGCATCATCACGGAACTCTCTGGAGAACCAGCACCTAAAAACGCCGGAT
TCCACCCCGAACTCCCCACGATTGTTCCCGGTTTTATTGATCTTCATAATCACGGTGGAAACGGTGGCGCGTTTCCTACG
GGAACGCAGGACCAGGCGAGGAACGCCGCGCAGTATCACCGCGAACATGGCACGACCGTGATGTTGGCAAGCATGGTTTC
GGCGCCGGCTGACGCACTGGCAGCGCAGGTGGAAAACCTTATTCCCTTGTGTGAAGAGGGCCTGCTGTGCGGCATTCACC
TCGAGGGCCCTTTCATCAACGCATGCCGTTGTGGTGCTCAAAACCCGGATTTCATTTTTCCCGGCAACCCAACAGATCTT
GCCCAGGTGATCCATGCGGGAAAAGGTTGGATCAAATCGATCACAGTAGCGCCGGAAACTGACAATCTTTCTGAGCTTCT
CGATCTCTGTGCAGCGCACCACATCATTGCTTCCTTCGGGCACACTGATGCAGATTTTGATACCACTACCAGCGCAATTG
CCTTGGCTAAAGAGAAAAATGTGACGGTCACGGCTACGCATTTGTTCAATGCGATGCCTCCGCTGCATCATAGGGCTCCC
GGCAGCGTGGGCGCTTTGCTTGCTGCGGCACGTGCCGGGGACGCATATGTTGAGTTGATCGCCGACGGCGTGCATTTGGC
CGATGGAACGGTCGATCTAGCTCGTTCCAACAACGCCTTTTTTATCACGGACGCCATGGAAGCCGCCGGAATGCCAGACG
GTGAGTACATTTTGGGCGTTTTGAACGTCACCGTCACCGATGGAGTCGCCCGTCTGCGCGATGGCGGCGCCATCGCCGGG
GGCACTAGCACACTAGCGAGTCAGTTCGTGCACCACGTGCGCAGGGGTATGACGCTTATCGACGCGACCCTCCACACCTC
AACCGTCGCCGCCAAAATTCTCGGACTTAGCGATCACGAAATCGCTAAATCCAACCCTGTAAATTTTGTGGTCTTTGACT
CAAACGGTCAGTTACAACAGGTCCATTTAGACCATCAAGTAATTTAA

Upstream 100 bases:

>100_bases
AACAGCAGGCCTCAAGTCCGAAGATAATTAACCCAAATCCGTAGACATAAGACATCATACGTCCTATGCTTGCTGGAAGG
AAGCAAATAACCTCAGAAAG

Downstream 100 bases:

>100_bases
ATACGAGCAAAACTTTCCTGATAATAAAAGGAGTCCGACCATGGACATCATCATCTGCAAAGACGAGCAAGAAGTCGGCA
AAGCAGCGGCAGCCCTGATC

Product: hypothetical protein

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MAEVVHYQENAGQAVKKIEGRIVTPHGVIDGFLQLENGIITELSGEPAPKNAGFHPELPTIVPGFIDLHNHGGNGGAFPT
GTQDQARNAAQYHREHGTTVMLASMVSAPADALAAQVENLIPLCEEGLLCGIHLEGPFINACRCGAQNPDFIFPGNPTDL
AQVIHAGKGWIKSITVAPETDNLSELLDLCAAHHIIASFGHTDADFDTTTSAIALAKEKNVTVTATHLFNAMPPLHHRAP
GSVGALLAAARAGDAYVELIADGVHLADGTVDLARSNNAFFITDAMEAAGMPDGEYILGVLNVTVTDGVARLRDGGAIAG
GTSTLASQFVHHVRRGMTLIDATLHTSTVAAKILGLSDHEIAKSNPVNFVVFDSNGQLQQVHLDHQVI

Sequences:

>Translated_388_residues
MAEVVHYQENAGQAVKKIEGRIVTPHGVIDGFLQLENGIITELSGEPAPKNAGFHPELPTIVPGFIDLHNHGGNGGAFPT
GTQDQARNAAQYHREHGTTVMLASMVSAPADALAAQVENLIPLCEEGLLCGIHLEGPFINACRCGAQNPDFIFPGNPTDL
AQVIHAGKGWIKSITVAPETDNLSELLDLCAAHHIIASFGHTDADFDTTTSAIALAKEKNVTVTATHLFNAMPPLHHRAP
GSVGALLAAARAGDAYVELIADGVHLADGTVDLARSNNAFFITDAMEAAGMPDGEYILGVLNVTVTDGVARLRDGGAIAG
GTSTLASQFVHHVRRGMTLIDATLHTSTVAAKILGLSDHEIAKSNPVNFVVFDSNGQLQQVHLDHQVI
>Mature_387_residues
AEVVHYQENAGQAVKKIEGRIVTPHGVIDGFLQLENGIITELSGEPAPKNAGFHPELPTIVPGFIDLHNHGGNGGAFPTG
TQDQARNAAQYHREHGTTVMLASMVSAPADALAAQVENLIPLCEEGLLCGIHLEGPFINACRCGAQNPDFIFPGNPTDLA
QVIHAGKGWIKSITVAPETDNLSELLDLCAAHHIIASFGHTDADFDTTTSAIALAKEKNVTVTATHLFNAMPPLHHRAPG
SVGALLAAARAGDAYVELIADGVHLADGTVDLARSNNAFFITDAMEAAGMPDGEYILGVLNVTVTDGVARLRDGGAIAGG
TSTLASQFVHHVRRGMTLIDATLHTSTVAAKILGLSDHEIAKSNPVNFVVFDSNGQLQQVHLDHQVI

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=266, Percent_Identity=32.7067669172932, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI224922791, Length=266, Percent_Identity=32.7067669172932, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1786892, Length=345, Percent_Identity=25.2173913043478, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17553768, Length=335, Percent_Identity=28.6567164179104, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI19920392, Length=277, Percent_Identity=30.6859205776173, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281361140, Length=290, Percent_Identity=29.6551724137931, Blast_Score=95, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40788; Mature: 40657

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVVHYQENAGQAVKKIEGRIVTPHGVIDGFLQLENGIITELSGEPAPKNAGFHPELPT
CCCEEEEHHHHHHHHHHHCCEEECCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCC
IVPGFIDLHNHGGNGGAFPTGTQDQARNAAQYHREHGTTVMLASMVSAPADALAAQVENL
CCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHCCHHHHHHHHHHH
IPLCEEGLLCGIHLEGPFINACRCGAQNPDFIFPGNPTDLAQVIHAGKGWIKSITVAPET
HHHHCCCCEEEEEECCCCCHHHHCCCCCCCEEECCCHHHHHHHHHCCCCCEEEEEECCCC
DNLSELLDLCAAHHIIASFGHTDADFDTTTSAIALAKEKNVTVTATHLFNAMPPLHHRAP
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEECCCEEEEHHHHHHCCCCCCCCCC
GSVGALLAAARAGDAYVELIADGVHLADGTVDLARSNNAFFITDAMEAAGMPDGEYILGV
CHHHHHHHHHHCCHHHHHHHHCCEEECCCCEEEEECCCEEEEEECHHHCCCCCCCEEEEE
LNVTVTDGVARLRDGGAIAGGTSTLASQFVHHVRRGMTLIDATLHTSTVAAKILGLSDHE
EEEEEHHHHHHHCCCCEECCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCC
IAKSNPVNFVVFDSNGQLQQVHLDHQVI
HHCCCCCEEEEECCCCCEEEEECCCCCC
>Mature Secondary Structure 
AEVVHYQENAGQAVKKIEGRIVTPHGVIDGFLQLENGIITELSGEPAPKNAGFHPELPT
CCEEEEHHHHHHHHHHHCCEEECCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCC
IVPGFIDLHNHGGNGGAFPTGTQDQARNAAQYHREHGTTVMLASMVSAPADALAAQVENL
CCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHCCHHHHHHHHHHH
IPLCEEGLLCGIHLEGPFINACRCGAQNPDFIFPGNPTDLAQVIHAGKGWIKSITVAPET
HHHHCCCCEEEEEECCCCCHHHHCCCCCCCEEECCCHHHHHHHHHCCCCCEEEEEECCCC
DNLSELLDLCAAHHIIASFGHTDADFDTTTSAIALAKEKNVTVTATHLFNAMPPLHHRAP
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEECCCEEEEHHHHHHCCCCCCCCCC
GSVGALLAAARAGDAYVELIADGVHLADGTVDLARSNNAFFITDAMEAAGMPDGEYILGV
CHHHHHHHHHHCCHHHHHHHHCCEEECCCCEEEEECCCEEEEEECHHHCCCCCCCEEEEE
LNVTVTDGVARLRDGGAIAGGTSTLASQFVHHVRRGMTLIDATLHTSTVAAKILGLSDHE
EEEEEHHHHHHHCCCCEECCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCC
IAKSNPVNFVVFDSNGQLQQVHLDHQVI
HHCCCCCEEEEECCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]