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The map label for this gene is cat1 [H]

Identifier: 145296564

GI number: 145296564

Start: 2728368

End: 2729909

Strand: Reverse

Name: cat1 [H]

Synonym: cgR_2472

Alternate gene names: 145296564

Gene position: 2729909-2728368 (Counterclockwise)

Preceding gene: 145296567

Following gene: 145296563

Centisome position: 82.37

GC content: 56.23

Gene sequence:

>1542_bases
TTGAAAAAGTCCGATTACCTGAGGAGGTATTCAATGTCTGATCGCATTGCTTCAGAAAAGCTGCGCTCCAAGCTCATGTC
CGCCGACGAGGCGGCACAGTTTGTTAACCACGGTGACAAGGTTGGTTTCTCCGGCTTCACCGGCGCTGGCTACCCAAAGG
CACTGCCTACGGCAATCGCTAACCGGGCTAAGGAAGCACACGGTGCAGGCAACGACTACGCAATTGACCTGTTCACTGGC
GCATCCACCGCACCTGACTGCGATGGCGTTCTGGCTGAAGCTGACGCAGTTCGCTGGCGTATGCCTTACGCATCTGATCC
AATCATGCGTAACAAGATCAACTCCGGCTCCATGGGATACTCCGATATCCACCTGTCCCACTCCGGCCAGCAGGTCGAAG
AGGGCTTCTTCGGCCAGCTCAACGTAGCTGTCATTGAAGTCACCCGCATTACCGAAGAGGGCTACATCATTCCTTCTTCC
TCCGTGGGTAACAACGTTGAGTGGCTCAACGCTGCCGAGAAGGTCATCCTCGAGGTTAACTCTTGGCAGTCTGAAGACCT
CGAAGGTATGCACGACATCTGGTCTGTTCCTGCCCTGCCAAACCGCATTGCAGTGCCAATCAACAAGCCAGGCGACCGCA
TCGGTAAGACCTACATCGAGTTCGACACCGACAAGGTTGTTGCTGTTGTTGAGACCAACACCGCAGACCGCAACGCACCA
TTCAAGCCTGTCGACGACATCTCTAAGAAGATCGCTGGCAACTTCCTCGACTTCCTGGAGAGCGAAGTCGCTGCAGGTCG
CCTGTCCTACGACGGCTACATCATGCAGTCCGGCGTGGGCAACGTGCCTAACGCTGTGATGGCAGGTCTGCTGGAATCCA
AGTTTGAGAACATCCAGGCCTACACCGAAGTTATCCAGGACGGCATGGTGGACCTCATCGACGCCGGCAAGATGACCGTT
GCATCCGCAACTTCCTTCTCCCTGTCTCCTGAGTACGCAGAGAAGATGAACAACGAGGCTAAGCGTTACCGCGAGTCCAT
TATCCTGCGCCCACAGCAGATCTCTAACCACCCAGAGGTCATCCGCCGCGTCGGCCTGATCGCCACCAACGGTCTCATCG
AGGCTGACATCTACGGCAACGTCAACTCCACCAACGTTTCTGGCTCCCGCGTCATGAACGGCATCGGCGGCTCCGGCGAC
TTCACCCGTAACGGCTACATCTCCAGCTTCATCACCCCTTCAGAGGCAAAGGGCGGCGCAATCTCTGCGATCGTTCCTTT
CGCATCCCACATCGACCACACCGAGCACGATGTCATGGTTGTTATCTCTGAGTACGGTTACGCAGACCTTCGTGGCCTGG
CTCCACGTGAGCGCGTTGCCAAGATGATCGGCCTGGCACACCCTGATTACCGCCCACTGCTCGAGGAGTACTACGCTCGC
GCAACCTCCGGTGACAACAAGTACATGCAGACCCCTCATGACCTTGCAACCGCGTTTGATTTCCACATCAACCTGGCTAA
GAACGGCTCCATGAAGGCATAA

Upstream 100 bases:

>100_bases
CTGCGTTAACGAATTTTGTCGGACGTTAAAATGGTCGCATTCTGCTTGCTGAAGTGGCACACCTATGTGTTCTGCTTGGG
TATAGCAGTGCGGGAAAAAT

Downstream 100 bases:

>100_bases
GTTTTTTCTTGGTTTAGAAACCGCCGCCTCGACAACATTTCGAGGCGGCGGCTTCTTTTATCACCTGGGTTTTGAGCGTT
AAATTAGACCAGGTCAGGCT

Product: hypothetical protein

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MKKSDYLRRYSMSDRIASEKLRSKLMSADEAAQFVNHGDKVGFSGFTGAGYPKALPTAIANRAKEAHGAGNDYAIDLFTG
ASTAPDCDGVLAEADAVRWRMPYASDPIMRNKINSGSMGYSDIHLSHSGQQVEEGFFGQLNVAVIEVTRITEEGYIIPSS
SVGNNVEWLNAAEKVILEVNSWQSEDLEGMHDIWSVPALPNRIAVPINKPGDRIGKTYIEFDTDKVVAVVETNTADRNAP
FKPVDDISKKIAGNFLDFLESEVAAGRLSYDGYIMQSGVGNVPNAVMAGLLESKFENIQAYTEVIQDGMVDLIDAGKMTV
ASATSFSLSPEYAEKMNNEAKRYRESIILRPQQISNHPEVIRRVGLIATNGLIEADIYGNVNSTNVSGSRVMNGIGGSGD
FTRNGYISSFITPSEAKGGAISAIVPFASHIDHTEHDVMVVISEYGYADLRGLAPRERVAKMIGLAHPDYRPLLEEYYAR
ATSGDNKYMQTPHDLATAFDFHINLAKNGSMKA

Sequences:

>Translated_513_residues
MKKSDYLRRYSMSDRIASEKLRSKLMSADEAAQFVNHGDKVGFSGFTGAGYPKALPTAIANRAKEAHGAGNDYAIDLFTG
ASTAPDCDGVLAEADAVRWRMPYASDPIMRNKINSGSMGYSDIHLSHSGQQVEEGFFGQLNVAVIEVTRITEEGYIIPSS
SVGNNVEWLNAAEKVILEVNSWQSEDLEGMHDIWSVPALPNRIAVPINKPGDRIGKTYIEFDTDKVVAVVETNTADRNAP
FKPVDDISKKIAGNFLDFLESEVAAGRLSYDGYIMQSGVGNVPNAVMAGLLESKFENIQAYTEVIQDGMVDLIDAGKMTV
ASATSFSLSPEYAEKMNNEAKRYRESIILRPQQISNHPEVIRRVGLIATNGLIEADIYGNVNSTNVSGSRVMNGIGGSGD
FTRNGYISSFITPSEAKGGAISAIVPFASHIDHTEHDVMVVISEYGYADLRGLAPRERVAKMIGLAHPDYRPLLEEYYAR
ATSGDNKYMQTPHDLATAFDFHINLAKNGSMKA
>Mature_513_residues
MKKSDYLRRYSMSDRIASEKLRSKLMSADEAAQFVNHGDKVGFSGFTGAGYPKALPTAIANRAKEAHGAGNDYAIDLFTG
ASTAPDCDGVLAEADAVRWRMPYASDPIMRNKINSGSMGYSDIHLSHSGQQVEEGFFGQLNVAVIEVTRITEEGYIIPSS
SVGNNVEWLNAAEKVILEVNSWQSEDLEGMHDIWSVPALPNRIAVPINKPGDRIGKTYIEFDTDKVVAVVETNTADRNAP
FKPVDDISKKIAGNFLDFLESEVAAGRLSYDGYIMQSGVGNVPNAVMAGLLESKFENIQAYTEVIQDGMVDLIDAGKMTV
ASATSFSLSPEYAEKMNNEAKRYRESIILRPQQISNHPEVIRRVGLIATNGLIEADIYGNVNSTNVSGSRVMNGIGGSGD
FTRNGYISSFITPSEAKGGAISAIVPFASHIDHTEHDVMVVISEYGYADLRGLAPRERVAKMIGLAHPDYRPLLEEYYAR
ATSGDNKYMQTPHDLATAFDFHINLAKNGSMKA

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=488, Percent_Identity=46.5163934426229, Blast_Score=426, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17538151, Length=399, Percent_Identity=25.31328320802, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32563853, Length=249, Percent_Identity=28.9156626506024, Blast_Score=75, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6319456, Length=515, Percent_Identity=39.2233009708738, Blast_Score=361, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 55918; Mature: 55918

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSDYLRRYSMSDRIASEKLRSKLMSADEAAQFVNHGDKVGFSGFTGAGYPKALPTAIA
CCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
NRAKEAHGAGNDYAIDLFTGASTAPDCDGVLAEADAVRWRMPYASDPIMRNKINSGSMGY
HHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHCCCHHEEECCCCCCCHHHCCCCCCCCCC
SDIHLSHSGQQVEEGFFGQLNVAVIEVTRITEEGYIIPSSSVGNNVEWLNAAEKVILEVN
EEEEECCCCCHHHCCCCCCEEEEEEEEEEECCCCEEEECCCCCCCCHHHHHHHHEEEEEC
SWQSEDLEGMHDIWSVPALPNRIAVPINKPGDRIGKTYIEFDTDKVVAVVETNTADRNAP
CCCCCCHHHHHHHHCCCCCCCCEEEECCCCCHHHCCEEEEECCCCEEEEEECCCCCCCCC
FKPVDDISKKIAGNFLDFLESEVAAGRLSYDGYIMQSGVGNVPNAVMAGLLESKFENIQA
CCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
YTEVIQDGMVDLIDAGKMTVASATSFSLSPEYAEKMNNEAKRYRESIILRPQQISNHPEV
HHHHHHCCHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHH
IRRVGLIATNGLIEADIYGNVNSTNVSGSRVMNGIGGSGDFTRNGYISSFITPSEAKGGA
HHHHHHHEECCEEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCE
ISAIVPFASHIDHTEHDVMVVISEYGYADLRGLAPRERVAKMIGLAHPDYRPLLEEYYAR
EEHHHHHHHHCCCCCCCEEEEEECCCCHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
ATSGDNKYMQTPHDLATAFDFHINLAKNGSMKA
HCCCCCCCCCCCHHHHHEEEEEEEEECCCCCCC
>Mature Secondary Structure
MKKSDYLRRYSMSDRIASEKLRSKLMSADEAAQFVNHGDKVGFSGFTGAGYPKALPTAIA
CCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
NRAKEAHGAGNDYAIDLFTGASTAPDCDGVLAEADAVRWRMPYASDPIMRNKINSGSMGY
HHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHCCCHHEEECCCCCCCHHHCCCCCCCCCC
SDIHLSHSGQQVEEGFFGQLNVAVIEVTRITEEGYIIPSSSVGNNVEWLNAAEKVILEVN
EEEEECCCCCHHHCCCCCCEEEEEEEEEEECCCCEEEECCCCCCCCHHHHHHHHEEEEEC
SWQSEDLEGMHDIWSVPALPNRIAVPINKPGDRIGKTYIEFDTDKVVAVVETNTADRNAP
CCCCCCHHHHHHHHCCCCCCCCEEEECCCCCHHHCCEEEEECCCCEEEEEECCCCCCCCC
FKPVDDISKKIAGNFLDFLESEVAAGRLSYDGYIMQSGVGNVPNAVMAGLLESKFENIQA
CCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHH
YTEVIQDGMVDLIDAGKMTVASATSFSLSPEYAEKMNNEAKRYRESIILRPQQISNHPEV
HHHHHHCCHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHH
IRRVGLIATNGLIEADIYGNVNSTNVSGSRVMNGIGGSGDFTRNGYISSFITPSEAKGGA
HHHHHHHEECCEEEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCE
ISAIVPFASHIDHTEHDVMVVISEYGYADLRGLAPRERVAKMIGLAHPDYRPLLEEYYAR
EEHHHHHHHHCCCCCCCEEEEEECCCCHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHH
ATSGDNKYMQTPHDLATAFDFHINLAKNGSMKA
HCCCCCCCCCCCHHHHHEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]