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The map label for this gene is murA [H]

Identifier: 145296553

GI number: 145296553

Start: 2717433

End: 2718689

Strand: Reverse

Name: murA [H]

Synonym: cgR_2462

Alternate gene names: 145296553

Gene position: 2718689-2717433 (Counterclockwise)

Preceding gene: 145296555

Following gene: 145296552

Centisome position: 82.03

GC content: 54.1

Gene sequence:

>1257_bases
GTGAAAGACAAGTTTTTAGTCACTGGTGGAGCACGGCTGCAGGGCGCTGTAAAAGTTGACGGCGCAAAAAACAGCGTTTT
GAAGCTCATGGCAGCAGCACTTCTCGCTGAAGGCACAACAACTCTGACCAATTGCCCCGAAATCCTCGACGTCCCCCTGA
TGCGCGACGTCCTCGTTGGTCTTGGCTGCGATGTCACCATCGACGGCTCAACCGTAACCATTACTACCCCTGCAGAACTC
AGCTCCAATGCTGACTTCCCAGCAGTCACCCAATTCCGTGCATCCGTATGTGTGCTTGGTCCATTGACAGCACGTTGTGG
TCGCGCAGTTGTATCCCTTCCCGGCGGTGACGCCATTGGATCCCGTCCACTCGACATGCATCAAAGCGGCCTGGAAAAGC
TTGGTGCCACCACCCGCATTTCCCACGGTGCAGTGGTTGCAGAAGCTGAAAAGCTCGTCGGTGCCAACATCACCCTGGAT
TTCCCGTCCGTCGGCGCCACCGAAAACATCCTCACTGCATCCGTCATGGCAGAAGGACGCACAGTATTAGATAACGCAGC
GCGCGAACCAGAAATTGTTGATCTCTGCCGTATGCTTCGTTCCATGGGCGCCAACATTGAAGGTGAAGGAAGCCCAACCA
TCACCATCGAAGGCGTAGAGAAACTCACCCCAACTCAGCACGAAGTAATCGGCGACCGCATCGTTGCCGGAACGTGGGCA
TACGCCGCTGCGATGACTCGTGGCGATATTACAGTTGGCGGAATCGCACCAAGGTATCTGCACCTTCCATTGGAAAAGCT
CAAGATCGCCGGCGCCAAGGTGGAAACCTACGAAAACGGCTTCCGCGTCCAAATGGATAAGCAGCCTGAGGCAACCGACT
ACCAAACCCTCCCGTTCCCAGGCTTCCCTACAGATCTGCAACCCATGGCAATTGGAATCAACGCAGTATCTAATGGAACT
TCAGTAATTACAGAGAATGTCTTTGAATCACGATTCCGCTTCGTCGATGAAATGCTTCGCCTGGGCGCTGACGCGAATGT
CGATGGGCACCACGTAGTAATCCGAGGAATTGAACAGCTTTCCTCTACTTCCGTGTGGTCTTCAGATATCCGTGCAGGAG
CAGGACTGGTTCTTGCCGCCCTTTGCGCAGACGGAGTGACCGAAGTTCACGATGTTTTCCACATCGACCGCGGATACCCC
AACTTCGTGGAAAATCTGCAGAAACTCGGAGCGACCATCGAAAGGGTTTCTTCCTAA

Upstream 100 bases:

>100_bases
CCCCGGTTCGCGTATAGATTTTGGTTAAATGAACGGCCATAACTTGAGATTTTAGCTGTCGTTACGCACAGGGGTGGGGA
ACACGGATAAGGTGGGGCAC

Downstream 100 bases:

>100_bases
CGAAGCCTTCCCATCAAGCATCCCCCAGCGAAACCATCATTGAGCTGGGGGTTTGTGCTTGCCAGGTGGGCTGTGTAGAT
TAATTCGAGTCAGCGCAACG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MKDKFLVTGGARLQGAVKVDGAKNSVLKLMAAALLAEGTTTLTNCPEILDVPLMRDVLVGLGCDVTIDGSTVTITTPAEL
SSNADFPAVTQFRASVCVLGPLTARCGRAVVSLPGGDAIGSRPLDMHQSGLEKLGATTRISHGAVVAEAEKLVGANITLD
FPSVGATENILTASVMAEGRTVLDNAAREPEIVDLCRMLRSMGANIEGEGSPTITIEGVEKLTPTQHEVIGDRIVAGTWA
YAAAMTRGDITVGGIAPRYLHLPLEKLKIAGAKVETYENGFRVQMDKQPEATDYQTLPFPGFPTDLQPMAIGINAVSNGT
SVITENVFESRFRFVDEMLRLGADANVDGHHVVIRGIEQLSSTSVWSSDIRAGAGLVLAALCADGVTEVHDVFHIDRGYP
NFVENLQKLGATIERVSS

Sequences:

>Translated_418_residues
MKDKFLVTGGARLQGAVKVDGAKNSVLKLMAAALLAEGTTTLTNCPEILDVPLMRDVLVGLGCDVTIDGSTVTITTPAEL
SSNADFPAVTQFRASVCVLGPLTARCGRAVVSLPGGDAIGSRPLDMHQSGLEKLGATTRISHGAVVAEAEKLVGANITLD
FPSVGATENILTASVMAEGRTVLDNAAREPEIVDLCRMLRSMGANIEGEGSPTITIEGVEKLTPTQHEVIGDRIVAGTWA
YAAAMTRGDITVGGIAPRYLHLPLEKLKIAGAKVETYENGFRVQMDKQPEATDYQTLPFPGFPTDLQPMAIGINAVSNGT
SVITENVFESRFRFVDEMLRLGADANVDGHHVVIRGIEQLSSTSVWSSDIRAGAGLVLAALCADGVTEVHDVFHIDRGYP
NFVENLQKLGATIERVSS
>Mature_418_residues
MKDKFLVTGGARLQGAVKVDGAKNSVLKLMAAALLAEGTTTLTNCPEILDVPLMRDVLVGLGCDVTIDGSTVTITTPAEL
SSNADFPAVTQFRASVCVLGPLTARCGRAVVSLPGGDAIGSRPLDMHQSGLEKLGATTRISHGAVVAEAEKLVGANITLD
FPSVGATENILTASVMAEGRTVLDNAAREPEIVDLCRMLRSMGANIEGEGSPTITIEGVEKLTPTQHEVIGDRIVAGTWA
YAAAMTRGDITVGGIAPRYLHLPLEKLKIAGAKVETYENGFRVQMDKQPEATDYQTLPFPGFPTDLQPMAIGINAVSNGT
SVITENVFESRFRFVDEMLRLGADANVDGHHVVIRGIEQLSSTSVWSSDIRAGAGLVLAALCADGVTEVHDVFHIDRGYP
NFVENLQKLGATIERVSS

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=417, Percent_Identity=45.5635491606715, Blast_Score=330, Evalue=9e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44178; Mature: 44178

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDKFLVTGGARLQGAVKVDGAKNSVLKLMAAALLAEGTTTLTNCPEILDVPLMRDVLVG
CCCCEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHH
LGCDVTIDGSTVTITTPAELSSNADFPAVTQFRASVCVLGPLTARCGRAVVSLPGGDAIG
CCCCEEECCCEEEEECCHHCCCCCCCCHHHHHHHCEEEECCHHHHHCCEEEECCCCCCCC
SRPLDMHQSGLEKLGATTRISHGAVVAEAEKLVGANITLDFPSVGATENILTASVMAEGR
CCCCHHHHHHHHHHCCCCEECCCCCEEEHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCC
TVLDNAAREPEIVDLCRMLRSMGANIEGEGSPTITIEGVEKLTPTQHEVIGDRIVAGTWA
HHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHCCCCHHHHHCCHHEECHHH
YAAAMTRGDITVGGIAPRYLHLPLEKLKIAGAKVETYENGFRVQMDKQPEATDYQTLPFP
HHHHHHCCCEEECCCCCHHHHCCHHHHHCCCCEEEECCCCEEEEECCCCCCCCCEECCCC
GFPTDLQPMAIGINAVSNGTSVITENVFESRFRFVDEMLRLGADANVDGHHVVIRGIEQL
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHH
SSTSVWSSDIRAGAGLVLAALCADGVTEVHDVFHIDRGYPNFVENLQKLGATIERVSS
HCCCCCHHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKDKFLVTGGARLQGAVKVDGAKNSVLKLMAAALLAEGTTTLTNCPEILDVPLMRDVLVG
CCCCEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHH
LGCDVTIDGSTVTITTPAELSSNADFPAVTQFRASVCVLGPLTARCGRAVVSLPGGDAIG
CCCCEEECCCEEEEECCHHCCCCCCCCHHHHHHHCEEEECCHHHHHCCEEEECCCCCCCC
SRPLDMHQSGLEKLGATTRISHGAVVAEAEKLVGANITLDFPSVGATENILTASVMAEGR
CCCCHHHHHHHHHHCCCCEECCCCCEEEHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCC
TVLDNAAREPEIVDLCRMLRSMGANIEGEGSPTITIEGVEKLTPTQHEVIGDRIVAGTWA
HHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHCCCCHHHHHCCHHEECHHH
YAAAMTRGDITVGGIAPRYLHLPLEKLKIAGAKVETYENGFRVQMDKQPEATDYQTLPFP
HHHHHHCCCEEECCCCCHHHHCCHHHHHCCCCEEEECCCCEEEEECCCCCCCCCEECCCC
GFPTDLQPMAIGINAVSNGTSVITENVFESRFRFVDEMLRLGADANVDGHHVVIRGIEQL
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHH
SSTSVWSSDIRAGAGLVLAALCADGVTEVHDVFHIDRGYPNFVENLQKLGATIERVSS
HCCCCCHHHHHCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]