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The map label for this gene is pgm [H]

Identifier: 145296537

GI number: 145296537

Start: 2688595

End: 2690259

Strand: Reverse

Name: pgm [H]

Synonym: cgR_2446

Alternate gene names: 145296537

Gene position: 2690259-2688595 (Counterclockwise)

Preceding gene: 145296541

Following gene: 145296536

Centisome position: 81.17

GC content: 59.82

Gene sequence:

>1665_bases
ATGGCACACGAACGCGCCGGGCAACTCGCCCAACCAGAAGATCTCATCGATGTTGCGGAACTGGTCACCGCATATTTCAC
CCGCAAGCCGGACGTGAACAATCCTGATCAGCAGGTCGCTTTCGGTACCTCCGGACACCGTGGCTCCGCGCTGGACAGCG
CTTTCAACGAGGACCACATCCTGGCAACTACCCAGGCCATCGTTGATTACCGCAACCAGCAGCCAAAAAACTGGGTCGGC
CCGCTATTCATCGGCCGTGATACGCACGCGCTCTCCGAGCCAGCGATGATCAGCGCGCTTGAGGTCCTCATTGCCAATGA
CGTCGAAGTGCTTGTCGACGCCGACGGCCGCTATACCCCTACGCCCGCAGTGTCCCACGCGATCCTGCGACACAACGATG
GCATCATCCTTGGCGCCGCAGGACCCTCCCGCCCTTACGCCGACGGCATCGTGATCACCCCATCCCACAACCCTCCTCGT
GATGGCGGGTTCAAATACAACCCAGCCAACGGTGGCCCTGCAGATACCGACGCCACGGACTGGATCGCCAACCGCGCCAA
CGATATCCTGCGCGGCGGCCTTGCAGACGTGAAGCGAGTTCCAGTTTCCGGTGTGCTTGACGAGCGCACCACTGCTTATG
ACTTCAAGGGCATTTACATCGCTGACCTGCCAAACGTGGTCAACATCGATGCCATCCGCGAAGCTGGTGTCCGAATCGGC
GCAGACCCAATGGGCGGCGCATCCGTGGATTACTGGGGTGCCATCGCTGAGACCCACGGCCTGAACCTCACCGTAGTCAA
CCCGCACGTTGACTCCACCTTCCGCTTTATGACACTGGACACCGACGGCAAGATCCGCATGGACTGCTCCAGCCCACACG
CTATGGCATCGTTGATCGAAAACCGCGACAAGTTCGATGTGGCAACCGGCAACGACGCCGACGCCGACCGCCACGGCATT
GTCACCCCAGACGCCGGCCTGATGAACCCCAACCACTACCTGGCCGTAGCAATCGAGTACCTCTTTGCACACCGCCCAGG
CTGGTCCGCAGACACTGCAGTGGGCAAAACCCTGGTCAGCTCCTCCATGATCGACCGTGTTGTGGCGCAGCTTGGCCGCA
CCCTTGTCGAGGTCCCCGTCGGATTCAAGTGGTTTGTCCCAGGCCTGATCTCTGGCGAAATCGGATTCGGTGGTGAAGAA
TCCGCAGGTGCATCCTTCCTCCGCATGGACGGCACCACCTGGTCCACCGACAAGGACGGTATTATTTTGGATCTTCTAGC
AGCTGAGATCATCGCCGTGACTGGTAAGACCCCATCCCAGCGTTATGCAGAACTCGCCGAAGAATTCGGCGCACCGGGCT
ATGCCCGCACCGATGCAGAAGCCAACCGCGAACAAAAGGCGATTTTGAAGGCACTGTCCCCAGAACAGGTCACCGCCACC
GAACTAGCCGGCGAAGCAATCACCGCTAAGCTCACCGAAGCTCCCGGCAATGGCGCAGCCATCGGAGGACTAAAAGTGAC
CACCGAAAACGCCTGGTTCGCAGCACGCCCATCCGGCACCGAAGACAAGTACAAGATCTACGCAGAATCCTTCAAGGGCG
TAGAGCACCTCGCCCAGGTTCAGAAGGAAGCCCAAGCGTTGGTCAGCGAAGTACTCGGACAGTAA

Upstream 100 bases:

>100_bases
TGTTAAGCCACCCTACTCCGTGAATTTTGCCGTATCTCGTGCGCAGAATTGCTTTTGAGGGAAAGATGGAGGAGAAGTAT
TGGTGTTTTAAGGAGCAAAC

Downstream 100 bases:

>100_bases
AACTGCGGACTTGCTGACAAGTTTCACAGGAGATAGAAAGATCTCCTGTGAATCTTGTCTCGAGCAACTAGTGGACGGGC
CAAATAAACTGCGCATGGTT

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MAHERAGQLAQPEDLIDVAELVTAYFTRKPDVNNPDQQVAFGTSGHRGSALDSAFNEDHILATTQAIVDYRNQQPKNWVG
PLFIGRDTHALSEPAMISALEVLIANDVEVLVDADGRYTPTPAVSHAILRHNDGIILGAAGPSRPYADGIVITPSHNPPR
DGGFKYNPANGGPADTDATDWIANRANDILRGGLADVKRVPVSGVLDERTTAYDFKGIYIADLPNVVNIDAIREAGVRIG
ADPMGGASVDYWGAIAETHGLNLTVVNPHVDSTFRFMTLDTDGKIRMDCSSPHAMASLIENRDKFDVATGNDADADRHGI
VTPDAGLMNPNHYLAVAIEYLFAHRPGWSADTAVGKTLVSSSMIDRVVAQLGRTLVEVPVGFKWFVPGLISGEIGFGGEE
SAGASFLRMDGTTWSTDKDGIILDLLAAEIIAVTGKTPSQRYAELAEEFGAPGYARTDAEANREQKAILKALSPEQVTAT
ELAGEAITAKLTEAPGNGAAIGGLKVTTENAWFAARPSGTEDKYKIYAESFKGVEHLAQVQKEAQALVSEVLGQ

Sequences:

>Translated_554_residues
MAHERAGQLAQPEDLIDVAELVTAYFTRKPDVNNPDQQVAFGTSGHRGSALDSAFNEDHILATTQAIVDYRNQQPKNWVG
PLFIGRDTHALSEPAMISALEVLIANDVEVLVDADGRYTPTPAVSHAILRHNDGIILGAAGPSRPYADGIVITPSHNPPR
DGGFKYNPANGGPADTDATDWIANRANDILRGGLADVKRVPVSGVLDERTTAYDFKGIYIADLPNVVNIDAIREAGVRIG
ADPMGGASVDYWGAIAETHGLNLTVVNPHVDSTFRFMTLDTDGKIRMDCSSPHAMASLIENRDKFDVATGNDADADRHGI
VTPDAGLMNPNHYLAVAIEYLFAHRPGWSADTAVGKTLVSSSMIDRVVAQLGRTLVEVPVGFKWFVPGLISGEIGFGGEE
SAGASFLRMDGTTWSTDKDGIILDLLAAEIIAVTGKTPSQRYAELAEEFGAPGYARTDAEANREQKAILKALSPEQVTAT
ELAGEAITAKLTEAPGNGAAIGGLKVTTENAWFAARPSGTEDKYKIYAESFKGVEHLAQVQKEAQALVSEVLGQ
>Mature_553_residues
AHERAGQLAQPEDLIDVAELVTAYFTRKPDVNNPDQQVAFGTSGHRGSALDSAFNEDHILATTQAIVDYRNQQPKNWVGP
LFIGRDTHALSEPAMISALEVLIANDVEVLVDADGRYTPTPAVSHAILRHNDGIILGAAGPSRPYADGIVITPSHNPPRD
GGFKYNPANGGPADTDATDWIANRANDILRGGLADVKRVPVSGVLDERTTAYDFKGIYIADLPNVVNIDAIREAGVRIGA
DPMGGASVDYWGAIAETHGLNLTVVNPHVDSTFRFMTLDTDGKIRMDCSSPHAMASLIENRDKFDVATGNDADADRHGIV
TPDAGLMNPNHYLAVAIEYLFAHRPGWSADTAVGKTLVSSSMIDRVVAQLGRTLVEVPVGFKWFVPGLISGEIGFGGEES
AGASFLRMDGTTWSTDKDGIILDLLAAEIIAVTGKTPSQRYAELAEEFGAPGYARTDAEANREQKAILKALSPEQVTATE
LAGEAITAKLTEAPGNGAAIGGLKVTTENAWFAARPSGTEDKYKIYAESFKGVEHLAQVQKEAQALVSEVLGQ

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786904, Length=556, Percent_Identity=62.0503597122302, Blast_Score=657, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=448, Percent_Identity=25.2232142857143, Blast_Score=75, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322722, Length=498, Percent_Identity=26.1044176706827, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17864244, Length=513, Percent_Identity=23.9766081871345, Blast_Score=83, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 59090; Mature: 58958

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHERAGQLAQPEDLIDVAELVTAYFTRKPDVNNPDQQVAFGTSGHRGSALDSAFNEDHI
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHCCCCCE
LATTQAIVDYRNQQPKNWVGPLFIGRDTHALSEPAMISALEVLIANDVEVLVDADGRYTP
EEHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCC
TPAVSHAILRHNDGIILGAAGPSRPYADGIVITPSHNPPRDGGFKYNPANGGPADTDATD
CHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCCHHH
WIANRANDILRGGLADVKRVPVSGVLDERTTAYDFKGIYIADLPNVVNIDAIREAGVRIG
HHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCEEEECCEEEECCCCCEEHHHHHHCCCEEC
ADPMGGASVDYWGAIAETHGLNLTVVNPHVDSTFRFMTLDTDGKIRMDCSSPHAMASLIE
CCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHC
NRDKFDVATGNDADADRHGIVTPDAGLMNPNHYLAVAIEYLFAHRPGWSADTAVGKTLVS
CCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
SSMIDRVVAQLGRTLVEVPVGFKWFVPGLISGEIGFGGEESAGASFLRMDGTTWSTDKDG
HHHHHHHHHHHHHHHHHCCCCCEECCCCCEECCCCCCCCCCCCCEEEEECCCCCCCCCCC
IILDLLAAEIIAVTGKTPSQRYAELAEEFGAPGYARTDAEANREQKAILKALSPEQVTAT
CHHHHHHHHHEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
ELAGEAITAKLTEAPGNGAAIGGLKVTTENAWFAARPSGTEDKYKIYAESFKGVEHLAQV
HHCCCCEEEEEECCCCCCEEECCEEEEECCCEEEECCCCCCCCEEHHHHHHHHHHHHHHH
QKEAQALVSEVLGQ
HHHHHHHHHHHHCC
>Mature Secondary Structure 
AHERAGQLAQPEDLIDVAELVTAYFTRKPDVNNPDQQVAFGTSGHRGSALDSAFNEDHI
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHCCCCCE
LATTQAIVDYRNQQPKNWVGPLFIGRDTHALSEPAMISALEVLIANDVEVLVDADGRYTP
EEHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCC
TPAVSHAILRHNDGIILGAAGPSRPYADGIVITPSHNPPRDGGFKYNPANGGPADTDATD
CHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCCHHH
WIANRANDILRGGLADVKRVPVSGVLDERTTAYDFKGIYIADLPNVVNIDAIREAGVRIG
HHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCEEEECCEEEECCCCCEEHHHHHHCCCEEC
ADPMGGASVDYWGAIAETHGLNLTVVNPHVDSTFRFMTLDTDGKIRMDCSSPHAMASLIE
CCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCEEEECCCHHHHHHHHC
NRDKFDVATGNDADADRHGIVTPDAGLMNPNHYLAVAIEYLFAHRPGWSADTAVGKTLVS
CCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
SSMIDRVVAQLGRTLVEVPVGFKWFVPGLISGEIGFGGEESAGASFLRMDGTTWSTDKDG
HHHHHHHHHHHHHHHHHCCCCCEECCCCCEECCCCCCCCCCCCCEEEEECCCCCCCCCCC
IILDLLAAEIIAVTGKTPSQRYAELAEEFGAPGYARTDAEANREQKAILKALSPEQVTAT
CHHHHHHHHHEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHH
ELAGEAITAKLTEAPGNGAAIGGLKVTTENAWFAARPSGTEDKYKIYAESFKGVEHLAQV
HHCCCCEEEEEECCCCCCEEECCEEEEECCCEEEECCCCCCCCEEHHHHHHHHHHHHHHH
QKEAQALVSEVLGQ
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083177; 8905232; 9278503; 8011018 [H]