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The map label for this gene is nrdF [H]

Identifier: 145296522

GI number: 145296522

Start: 2674482

End: 2675486

Strand: Reverse

Name: nrdF [H]

Synonym: cgR_2432

Alternate gene names: 145296522

Gene position: 2675486-2674482 (Counterclockwise)

Preceding gene: 145296525

Following gene: 145296521

Centisome position: 80.73

GC content: 51.64

Gene sequence:

>1005_bases
ATGGCTGCTGATTCTGATCTCAGTGTTCACGATGCTTACTTAAAGGAGCATGTTGCACCTGTAAAGGCGATCAACTGGAA
CTCCATCCCAGATTCCAAAGATCTTGAAGTCTGGGATCGTCTGACCGGTAACTTCTGGCTCCCAGAAAAGGTCCCAGTAT
CCAACGACATCAAGAGCTGGGGAACCCTCAACGATGTTGAAAAAGCCGCAACCATGCGCGTGTTCACCGGACTTACCCTG
CTGGACACCATTCAGGGCACTGTCGGCGCAATCTCCCTGCTTCCAGACGCAGATTCACTGCACGAAGAAGCGGTGCTAAC
CAACATTGCGTTCATGGAATCCGTGCACGCAAAGAGTTACTCCAACATCTTCATGACTCTGGCCTCCACCGCGGAAATCA
ACGATGCGTTCCGTTGGTCTGAGGAAAATGAAAACCTGCAGCGCAAGGCAAAGATCATCCTGTCTTACTACGAGGGTGAT
GATCCACTAAAGCGCAAGATCGCCTCCGTGATCCTGGAGTCCTTCCTGTTCTACTCCGGCTTCTACCTCCCAATGTATTG
GTCCAGCCACTCCAAGCTGACCAACACCGCCGACGTGATCCGCCTGATCATCCGCGATGAGGCAGTGCACGGCTACTACA
TTGGCTACAAGTACCAAAAGGCTGTCGCGAAGGAGACTCCAGAGCGTCAGGAAGAGCTGAAGGAGTACACCTTCGATCTG
CTCTACGATCTTTATGATAACGAAACTCAGTACTCCGAAGATCTCTACGACGATCTTGGATGGACCGAGGATGTTAAGCG
ATTCCTTCGCTACAACGCCAACAAGGCCCTCAACAACCTTGGCTACGAAGGACTCTTCCCAGCGGATGAAACCAAGGTGT
CCCCAAACATCTTGTCTGCGCTGTCACCAAACGCTGATGAGAACCACGACTTCTTCTCCGGCTCCGGTTCCTCTTACGTT
ATTGGTAAGGCAGAAAACACCGAGGATGATGACTGGGACTTCTAA

Upstream 100 bases:

>100_bases
CTTCTGAAGGGCTTCGGTTGGGGTAAGCTGGCGATCTGAAATCGCGCTGCATTGTGGCGTCGAAAAGCAAAAAAATTTGT
AGAAGGGAAGAGCGCACCTA

Downstream 100 bases:

>100_bases
CTTTTAAAAAGCTGAAGCGCTCTACGGCTGTAGGTAACTGCAACCGTTAGAGCGTTTTTCGCTTTCTGGTGGGGACTTAA
GGTGCGGGTTTTTCCGAAGC

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAADSDLSVHDAYLKEHVAPVKAINWNSIPDSKDLEVWDRLTGNFWLPEKVPVSNDIKSWGTLNDVEKAATMRVFTGLTL
LDTIQGTVGAISLLPDADSLHEEAVLTNIAFMESVHAKSYSNIFMTLASTAEINDAFRWSEENENLQRKAKIILSYYEGD
DPLKRKIASVILESFLFYSGFYLPMYWSSHSKLTNTADVIRLIIRDEAVHGYYIGYKYQKAVAKETPERQEELKEYTFDL
LYDLYDNETQYSEDLYDDLGWTEDVKRFLRYNANKALNNLGYEGLFPADETKVSPNILSALSPNADENHDFFSGSGSSYV
IGKAENTEDDDWDF

Sequences:

>Translated_334_residues
MAADSDLSVHDAYLKEHVAPVKAINWNSIPDSKDLEVWDRLTGNFWLPEKVPVSNDIKSWGTLNDVEKAATMRVFTGLTL
LDTIQGTVGAISLLPDADSLHEEAVLTNIAFMESVHAKSYSNIFMTLASTAEINDAFRWSEENENLQRKAKIILSYYEGD
DPLKRKIASVILESFLFYSGFYLPMYWSSHSKLTNTADVIRLIIRDEAVHGYYIGYKYQKAVAKETPERQEELKEYTFDL
LYDLYDNETQYSEDLYDDLGWTEDVKRFLRYNANKALNNLGYEGLFPADETKVSPNILSALSPNADENHDFFSGSGSSYV
IGKAENTEDDDWDF
>Mature_333_residues
AADSDLSVHDAYLKEHVAPVKAINWNSIPDSKDLEVWDRLTGNFWLPEKVPVSNDIKSWGTLNDVEKAATMRVFTGLTLL
DTIQGTVGAISLLPDADSLHEEAVLTNIAFMESVHAKSYSNIFMTLASTAEINDAFRWSEENENLQRKAKIILSYYEGDD
PLKRKIASVILESFLFYSGFYLPMYWSSHSKLTNTADVIRLIIRDEAVHGYYIGYKYQKAVAKETPERQEELKEYTFDLL
YDLYDNETQYSEDLYDDLGWTEDVKRFLRYNANKALNNLGYEGLFPADETKVSPNILSALSPNADENHDFFSGSGSSYVI
GKAENTEDDDWDF

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Escherichia coli, GI1789031, Length=314, Percent_Identity=70.0636942675159, Blast_Score=459, Evalue=1e-131,
Organism=Escherichia coli, GI1788567, Length=290, Percent_Identity=26.2068965517241, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 38041; Mature: 37910

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS00368 RIBORED_SMALL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAADSDLSVHDAYLKEHVAPVKAINWNSIPDSKDLEVWDRLTGNFWLPEKVPVSNDIKSW
CCCCCCCHHHHHHHHHHCCCHHEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHC
GTLNDVEKAATMRVFTGLTLLDTIQGTVGAISLLPDADSLHEEAVLTNIAFMESVHAKSY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
SNIFMTLASTAEINDAFRWSEENENLQRKAKIILSYYEGDDPLKRKIASVILESFLFYSG
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHCC
FYLPMYWSSHSKLTNTADVIRLIIRDEAVHGYYIGYKYQKAVAKETPERQEELKEYTFDL
CEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCHHHHHHHHHHHHHH
LYDLYDNETQYSEDLYDDLGWTEDVKRFLRYNANKALNNLGYEGLFPADETKVSPNILSA
HHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCHHHHHH
LSPNADENHDFFSGSGSSYVIGKAENTEDDDWDF
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
AADSDLSVHDAYLKEHVAPVKAINWNSIPDSKDLEVWDRLTGNFWLPEKVPVSNDIKSW
CCCCCCHHHHHHHHHHCCCHHEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHC
GTLNDVEKAATMRVFTGLTLLDTIQGTVGAISLLPDADSLHEEAVLTNIAFMESVHAKSY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
SNIFMTLASTAEINDAFRWSEENENLQRKAKIILSYYEGDDPLKRKIASVILESFLFYSG
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHCC
FYLPMYWSSHSKLTNTADVIRLIIRDEAVHGYYIGYKYQKAVAKETPERQEELKEYTFDL
CEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCHHHHHHHHHHHHHH
LYDLYDNETQYSEDLYDDLGWTEDVKRFLRYNANKALNNLGYEGLFPADETKVSPNILSA
HHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCHHHHHH
LSPNADENHDFFSGSGSSYVIGKAENTEDDDWDF
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]