BacMap

Definition	Corynebacterium glutamicum R chromosome, complete genome.
Accession	NC_009342
Length	3,314,179

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The map label for this gene is bdhA [H]

Identifier: 145296496

GI number: 145296496

Start: 2651641

End: 2652402

Strand: Reverse

Name: bdhA [H]

Synonym: cgR_2407

Alternate gene names: 145296496

Gene position: 2652402-2651641 (Counterclockwise)

Preceding gene: 145296497

Following gene: 145296495

Centisome position: 80.03

GC content: 51.71

Gene sequence:

>762_bases
ATGTCTCAGTCCACCAACATTTCACTTGAAGGTCGCACAGCTTTGATTACTGGAGGTGCATCTGGGATTGGGGCGGCTTG
TGCTCGTGCGTTCTCTCGGGCAGGTGCCACAGTGACGGTGTGTGATCGGAATGAGCAGGCAGCGAAAGAGTTGGCTGAAG
AAATTGGGGGAGATTACTGGGCCGTGGATCTCTCAGATACCAAGGCGTTGGAGTTTCTCACCTTAGATGTGGATATTTTG
GTCAATAACGCCGGTAGTCAAAAAGTCGCGCCGATTCATGAGTTCGTTCCGGATGATTGGCGCTTCATTCACAAGCTGAT
GTTGGAATCCCCTTTCCTTCTAATTCGTGCCGCATTGCCCGCGATGTATGAGCGTGGATTCGGACGCATCATTAATATTT
CCTCCATCCATGGGCTTCGTGCGAGTGCTTTTAAATCGGCGTATGTGGCTGCAAAGCATGGCCTGGAAAGCCTTTCGAAA
GTTACGGCCCTGGAGGGTGCGGAATATGGGGTGACATCTAACTGCATGAATCCTTCTTATGTGCGGACTGCTTTAGTGGA
GAAACAGATTAAAGATCAGGCAGTCACACATGGCATTGCTCCAGAAGAAGTGGTGGAGAAGATCATGCTTACAGAATCTG
CGATAAAGGGACTTGTCGATGCGGATGAGGTCGCCTCTTTGGTCACGTGGCTGGCATCCGACATGGCGGGCATGGTTACC
GGCGCGTCTTACACCGTGGATGGTGGCTGGACAGCCAGCTAG

Upstream 100 bases:

>100_bases
CTACAAAAATCGCGAGAGAAAATTGCACCTATATATATGGTGCGAATCAGAAGTGGTTGGCATTCTGTTCTATATCTCAA
TAATGAAAGCGGGAAAAGGT

Downstream 100 bases:

>100_bases
AACCTACACTTTGAAGGCATGAGTATTTCGCACGATTTCGATGCCTGGATGGAAGATCGGGGCATTGTTGCTGAAGCTGA
GGTTATACCGGATCATGCGT

Product: hypothetical protein

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MSQSTNISLEGRTALITGGASGIGAACARAFSRAGATVTVCDRNEQAAKELAEEIGGDYWAVDLSDTKALEFLTLDVDIL
VNNAGSQKVAPIHEFVPDDWRFIHKLMLESPFLLIRAALPAMYERGFGRIINISSIHGLRASAFKSAYVAAKHGLESLSK
VTALEGAEYGVTSNCMNPSYVRTALVEKQIKDQAVTHGIAPEEVVEKIMLTESAIKGLVDADEVASLVTWLASDMAGMVT
GASYTVDGGWTAS

Sequences:

>Translated_253_residues
MSQSTNISLEGRTALITGGASGIGAACARAFSRAGATVTVCDRNEQAAKELAEEIGGDYWAVDLSDTKALEFLTLDVDIL
VNNAGSQKVAPIHEFVPDDWRFIHKLMLESPFLLIRAALPAMYERGFGRIINISSIHGLRASAFKSAYVAAKHGLESLSK
VTALEGAEYGVTSNCMNPSYVRTALVEKQIKDQAVTHGIAPEEVVEKIMLTESAIKGLVDADEVASLVTWLASDMAGMVT
GASYTVDGGWTAS
>Mature_252_residues
SQSTNISLEGRTALITGGASGIGAACARAFSRAGATVTVCDRNEQAAKELAEEIGGDYWAVDLSDTKALEFLTLDVDILV
NNAGSQKVAPIHEFVPDDWRFIHKLMLESPFLLIRAALPAMYERGFGRIINISSIHGLRASAFKSAYVAAKHGLESLSKV
TALEGAEYGVTSNCMNPSYVRTALVEKQIKDQAVTHGIAPEEVVEKIMLTESAIKGLVDADEVASLVTWLASDMAGMVTG
ASYTVDGGWTAS

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=272, Percent_Identity=30.8823529411765, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI66933014, Length=247, Percent_Identity=31.1740890688259, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI20149619, Length=258, Percent_Identity=29.8449612403101, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=29.718875502008, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI4504505, Length=264, Percent_Identity=29.1666666666667, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI157739938, Length=231, Percent_Identity=26.4069264069264, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=26.7716535433071, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=30.2040816326531, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=27.8195488721804, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI59889578, Length=233, Percent_Identity=30.0429184549356, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI4503301, Length=256, Percent_Identity=25.390625, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI142976729, Length=228, Percent_Identity=28.0701754385965, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI226371731, Length=199, Percent_Identity=27.6381909547739, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI109715829, Length=226, Percent_Identity=28.7610619469027, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=33.852140077821, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=31.2252964426877, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=32.8063241106719, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=29.296875, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=33.0708661417323, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787905, Length=261, Percent_Identity=31.0344827586207, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=29.4117647058824, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=29.1338582677165, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=27.906976744186, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1787820, Length=170, Percent_Identity=31.7647058823529, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787526, Length=193, Percent_Identity=31.0880829015544, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=28.6821705426357, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=28.4046692607004, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786701, Length=245, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=253, Percent_Identity=29.2490118577075, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25147288, Length=260, Percent_Identity=30.3846153846154, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=29.1828793774319, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI115534694, Length=256, Percent_Identity=26.953125, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=264, Percent_Identity=25.7575757575758, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=29.3650793650794, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=196, Percent_Identity=30.6122448979592, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=28.968253968254, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=226, Percent_Identity=30.5309734513274, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=224, Percent_Identity=30.8035714285714, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=270, Percent_Identity=28.5185185185185, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=263, Percent_Identity=25.8555133079848, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=230, Percent_Identity=26.0869565217391, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=194, Percent_Identity=28.3505154639175, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=24.4186046511628, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=280, Percent_Identity=24.6428571428571, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=231, Percent_Identity=30.7359307359307, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=31.3725490196078, Blast_Score=113, Evalue=9e-26,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=31.2252964426877, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24644339, Length=264, Percent_Identity=31.4393939393939, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21358495, Length=240, Percent_Identity=29.5833333333333, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI21357041, Length=269, Percent_Identity=29.7397769516729, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=29.4573643410853, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=28.4046692607004, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI18859837, Length=197, Percent_Identity=32.48730964467, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=27.6, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24640492, Length=143, Percent_Identity=32.1678321678322, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28574402, Length=190, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24584744, Length=190, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24644337, Length=256, Percent_Identity=30.46875, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355631, Length=241, Percent_Identity=25.7261410788382, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 26915; Mature: 26784

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSTNISLEGRTALITGGASGIGAACARAFSRAGATVTVCDRNEQAAKELAEEIGGDYW
CCCCCCEEECCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCEE
AVDLSDTKALEFLTLDVDILVNNAGSQKVAPIHEFVPDDWRFIHKLMLESPFLLIRAALP
EEECCCCCEEEEEEEEEEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHCCHHHHHHHHHH
AMYERGFGRIINISSIHGLRASAFKSAYVAAKHGLESLSKVTALEGAEYGVTSNCMNPSY
HHHHCCCCCEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
VRTALVEKQIKDQAVTHGIAPEEVVEKIMLTESAIKGLVDADEVASLVTWLASDMAGMVT
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
GASYTVDGGWTAS
CCEEEECCCCCCC
>Mature Secondary Structure 
SQSTNISLEGRTALITGGASGIGAACARAFSRAGATVTVCDRNEQAAKELAEEIGGDYW
CCCCCEEECCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCEE
AVDLSDTKALEFLTLDVDILVNNAGSQKVAPIHEFVPDDWRFIHKLMLESPFLLIRAALP
EEECCCCCEEEEEEEEEEEEEECCCCCCCCHHHHHCCCHHHHHHHHHHCCHHHHHHHHHH
AMYERGFGRIINISSIHGLRASAFKSAYVAAKHGLESLSKVTALEGAEYGVTSNCMNPSY
HHHHCCCCCEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
VRTALVEKQIKDQAVTHGIAPEEVVEKIMLTESAIKGLVDADEVASLVTWLASDMAGMVT
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
GASYTVDGGWTAS
CCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]