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The map label for this gene is betT [H]

Identifier: 145296476

GI number: 145296476

Start: 2624332

End: 2626629

Strand: Reverse

Name: betT [H]

Synonym: cgR_2388

Alternate gene names: 145296476

Gene position: 2626629-2624332 (Counterclockwise)

Preceding gene: 145296477

Following gene: 145296474

Centisome position: 79.25

GC content: 50.96

Gene sequence:

>2298_bases
GTGAGCGACAATTCGCAGAGTATTCCTGATTCTGGCGATAAGCCGAAGCAGGATGTGAACACTCAAGCGCTCCGAGAATC
TGTGAAGCGCGATGAACTTGGTGGTCGTAATCGATCGCCGAAGGAGGAGGAGCGGCGTCAAAACCGTCCTCCGGTTTCGC
GTGAAGATCTGTCTAAGGGGGCCCAAGTTTTTGGTGATGCCAAGGTCAACTGGTTTGTTCTTGGTATCAGTGCCGCAATT
ATTCTTGCCTTTTCTATTTGGGCCATGATGGCACCTGATCATGCTTTCAACACGATGGAAAGCATTGTTGGTTTCATCGG
CGAGAGCCTTGGTTGGTACTACGTGTTGACAGTATTTATTGTCATTGCGTTCGTGTTGTGGGTTGCGTTGTCTAGGACTG
GAAAAGTCCGTTTGGGCCCTGATCATTCACGGCCTCACTACAGTTTGTTTACTTGGGTTTCCATGCTGTTTGCTGCTGGT
GTGGGCATTGACATGCTATTTTACTCAGTAACCGGGCCTATTACTCAATATGTCACCCCACCTGATGCTGATCCTGAATC
GGCGGCTGCTGCACGAGATGCTGTGGTGTGGACAATGTTCCACTACGGCATTGGTGGCTGGGCTATGTATTCATTGCTAG
GCATGGCGATGGGCTATTTTGCTTATCGCTGGGGAATGCCACTTTCTGTTCGTGCTGCACTTTATCCACTGCTGGGTAAA
CGAGTCCGAGGTAAAGCTGGTGACGCCATTGATATTGTCACCCTCGTTGGCACAGTGATGGGTGTTGCAACATCCATGGG
CATCGGCGTGGTGTTGTTGTCGGTCGGTTTCTCTAAACTCTTTGGTTTTACTGATGGTTTGGGCCTTCAAATTGCGCTGG
TGATCGTCGCTGTTGTGATCACCATTGCAGCTTGCACCTCTGGTGTGGATAAGGGCGTTCGCCTAATTTCGGAGCTCAAC
CTGTGGAGTGCAGGTGCAATGATTTTGTACATCATTGTTACTGGTCGAACCTCATTCCTGCTCAACGGCATGGTGGAAAA
CATCGGCCGCTTCATCAACACCCTTCCAGAGCGTTCTCTCCAGACGATGGTCTACCAAGAGGGCGGATCTGATTGGATGG
CTGGATGGACCCTGTTTTTCTGGGCGTTTTGGCTGGCATGGGGACCATTCGTGGGCATGTTCCTCGCTCGAATTTCTCGT
GGTCGAACCTTGAGAGAATTCGTTATCGCCGCTATTACCGTTCCGGTTCTGTGTGACTTCCTCATTGTCACCACCTTCGG
TAACTCAGCAATGTATGAGGTCCTCAACGGCAATGATGCTTTTGCACAACTTGCGATGGAATCACCAGAACAAGGTTGGT
ACACCCTCTTGGAGATGTTCCCAGGTGCAACCTTCCTCATTGGCCTTGCCACACTATCTGGCTTGTTGTTCTATCTGACC
TCTGCAAACTCAGGTGCGATGGTAATGGCCAACTTCTCCTCATCAATTCCTGATCCTGCACAAGATGGTGCAAAATGGCT
CCGCATTCTGTGGGCGGTGATCACTGCGATCTTGACCATCGCTATGTTGCTGGCTGGCGGTGTCACCACCATGGAATATG
CGACGCTGATCTTCGCGCTTCCTGTAACGATCATTGCGTACCTGGTCATGGCGTCTTTCCTCAAGGTGCTTCGCATGGAG
CGTGCAGAGATGGAAGGCCGGCGCCTATTCAACCAGCACGTGGCAACTGACGGCGGTAGCGCACCAGAGAAAACCTGGCG
TCAACGTCTGGCAAGTATGCGTTCCTACCCAAGTAGAGACCAGGTGGAAAAGTATGTCCGGACCACTGTGGAGCCTGCAC
TAAAGGATGTGTACAAGGAGTTCCGTCGCCTTGGTTATGAAACTGAATTGTTTAGCGATTTCGATGCAGCGTCGAATATC
CCTACCCACGTGTTGCTGGTCAACATTGAAAACCAGCGCAGGTTCCAGTACTTCGTGGCACCAGTTCCAACACCCATCCC
ATCATTTGGTGGACGTCGAGCACAAACAGAAGATAGCTACTACAGGCTAGAAGTGTTCAATCAGACCGGCACGGAAGGCT
ATGACCTCATGGGGTTGAGCAAGCAGCAGGTGATTGATGATGTCATCGACCGCTATGAAACCCACATGACCTTCCTGACG
TTGACTTTCAACCTGGATAATCCATCATTTTTGACTCCTCCGCAGCCACCCGTCGCAGAACCAGCATTGGCAGAGCAAGA
GGAAGAAATCGTGACGGAACAACAGCAGTTAGAAACTGGTGATTCCGACAGAACTTAG

Upstream 100 bases:

>100_bases
AAAAACTGAGGCATGCCCGATTGCGGGTTCCGGCTTTGCCATGGGCGGATGAAACTACACCACGCAACTGAACATGGAAT
AAATAGGGAAGGAGTAATGA

Downstream 100 bases:

>100_bases
ACCTGGGTCTCAAACAAAGCCTTCTTCCACAAGCACACATCCACCTTTGGTGATCACGTGTGCTTGCCCGGATCCTCCAA
CCACACGAGACCAGCTTTCA

Product: hypothetical protein

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 765; Mature: 764

Protein sequence:

>765_residues
MSDNSQSIPDSGDKPKQDVNTQALRESVKRDELGGRNRSPKEEERRQNRPPVSREDLSKGAQVFGDAKVNWFVLGISAAI
ILAFSIWAMMAPDHAFNTMESIVGFIGESLGWYYVLTVFIVIAFVLWVALSRTGKVRLGPDHSRPHYSLFTWVSMLFAAG
VGIDMLFYSVTGPITQYVTPPDADPESAAAARDAVVWTMFHYGIGGWAMYSLLGMAMGYFAYRWGMPLSVRAALYPLLGK
RVRGKAGDAIDIVTLVGTVMGVATSMGIGVVLLSVGFSKLFGFTDGLGLQIALVIVAVVITIAACTSGVDKGVRLISELN
LWSAGAMILYIIVTGRTSFLLNGMVENIGRFINTLPERSLQTMVYQEGGSDWMAGWTLFFWAFWLAWGPFVGMFLARISR
GRTLREFVIAAITVPVLCDFLIVTTFGNSAMYEVLNGNDAFAQLAMESPEQGWYTLLEMFPGATFLIGLATLSGLLFYLT
SANSGAMVMANFSSSIPDPAQDGAKWLRILWAVITAILTIAMLLAGGVTTMEYATLIFALPVTIIAYLVMASFLKVLRME
RAEMEGRRLFNQHVATDGGSAPEKTWRQRLASMRSYPSRDQVEKYVRTTVEPALKDVYKEFRRLGYETELFSDFDAASNI
PTHVLLVNIENQRRFQYFVAPVPTPIPSFGGRRAQTEDSYYRLEVFNQTGTEGYDLMGLSKQQVIDDVIDRYETHMTFLT
LTFNLDNPSFLTPPQPPVAEPALAEQEEEIVTEQQQLETGDSDRT

Sequences:

>Translated_765_residues
MSDNSQSIPDSGDKPKQDVNTQALRESVKRDELGGRNRSPKEEERRQNRPPVSREDLSKGAQVFGDAKVNWFVLGISAAI
ILAFSIWAMMAPDHAFNTMESIVGFIGESLGWYYVLTVFIVIAFVLWVALSRTGKVRLGPDHSRPHYSLFTWVSMLFAAG
VGIDMLFYSVTGPITQYVTPPDADPESAAAARDAVVWTMFHYGIGGWAMYSLLGMAMGYFAYRWGMPLSVRAALYPLLGK
RVRGKAGDAIDIVTLVGTVMGVATSMGIGVVLLSVGFSKLFGFTDGLGLQIALVIVAVVITIAACTSGVDKGVRLISELN
LWSAGAMILYIIVTGRTSFLLNGMVENIGRFINTLPERSLQTMVYQEGGSDWMAGWTLFFWAFWLAWGPFVGMFLARISR
GRTLREFVIAAITVPVLCDFLIVTTFGNSAMYEVLNGNDAFAQLAMESPEQGWYTLLEMFPGATFLIGLATLSGLLFYLT
SANSGAMVMANFSSSIPDPAQDGAKWLRILWAVITAILTIAMLLAGGVTTMEYATLIFALPVTIIAYLVMASFLKVLRME
RAEMEGRRLFNQHVATDGGSAPEKTWRQRLASMRSYPSRDQVEKYVRTTVEPALKDVYKEFRRLGYETELFSDFDAASNI
PTHVLLVNIENQRRFQYFVAPVPTPIPSFGGRRAQTEDSYYRLEVFNQTGTEGYDLMGLSKQQVIDDVIDRYETHMTFLT
LTFNLDNPSFLTPPQPPVAEPALAEQEEEIVTEQQQLETGDSDRT
>Mature_764_residues
SDNSQSIPDSGDKPKQDVNTQALRESVKRDELGGRNRSPKEEERRQNRPPVSREDLSKGAQVFGDAKVNWFVLGISAAII
LAFSIWAMMAPDHAFNTMESIVGFIGESLGWYYVLTVFIVIAFVLWVALSRTGKVRLGPDHSRPHYSLFTWVSMLFAAGV
GIDMLFYSVTGPITQYVTPPDADPESAAAARDAVVWTMFHYGIGGWAMYSLLGMAMGYFAYRWGMPLSVRAALYPLLGKR
VRGKAGDAIDIVTLVGTVMGVATSMGIGVVLLSVGFSKLFGFTDGLGLQIALVIVAVVITIAACTSGVDKGVRLISELNL
WSAGAMILYIIVTGRTSFLLNGMVENIGRFINTLPERSLQTMVYQEGGSDWMAGWTLFFWAFWLAWGPFVGMFLARISRG
RTLREFVIAAITVPVLCDFLIVTTFGNSAMYEVLNGNDAFAQLAMESPEQGWYTLLEMFPGATFLIGLATLSGLLFYLTS
ANSGAMVMANFSSSIPDPAQDGAKWLRILWAVITAILTIAMLLAGGVTTMEYATLIFALPVTIIAYLVMASFLKVLRMER
AEMEGRRLFNQHVATDGGSAPEKTWRQRLASMRSYPSRDQVEKYVRTTVEPALKDVYKEFRRLGYETELFSDFDAASNIP
THVLLVNIENQRRFQYFVAPVPTPIPSFGGRRAQTEDSYYRLEVFNQTGTEGYDLMGLSKQQVIDDVIDRYETHMTFLTL
TFNLDNPSFLTPPQPPVAEPALAEQEEEIVTEQQQLETGDSDRT

Specific function: High-affinity uptake of choline driven by a proton- motive force [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=668, Percent_Identity=41.9161676646707, Blast_Score=573, Evalue=1e-164,
Organism=Escherichia coli, GI1788102, Length=476, Percent_Identity=26.4705882352941, Blast_Score=166, Evalue=5e-42,
Organism=Escherichia coli, GI1786224, Length=476, Percent_Identity=25.4201680672269, Blast_Score=146, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 84735; Mature: 84604

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SDNSQSIPDSGDKPKQDVNTQALRESVKRDELGGRNRSPKEEERRQNRPPVSREDLSKG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCHHHHHHH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EEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]