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The map label for this gene is orn

Identifier: 145296472

GI number: 145296472

Start: 2619597

End: 2620256

Strand: Direct

Name: orn

Synonym: cgR_2384

Alternate gene names: 145296472

Gene position: 2619597-2620256 (Clockwise)

Preceding gene: 145296471

Following gene: 145296475

Centisome position: 79.04

GC content: 55.61

Gene sequence:

>660_bases
GTGTCTGAATCTGAAAACAACACAACACCAGCAGTCGCTGCTCGCGATGACCGCCTGGTCTGGGTCGATCTGGAAATGAC
TGGCTTGGATTTGAAGCGCCACGTGATCGTGGAGGTCGCAGCCCTGGTCACTGACGCTAACCTCAACGTTTTGGGCGAGG
GCGTGGACTTGGTTGTTCACGCAACTGAAGAAGAGCTCGCGCAGATGGATGATTTTGTCACCAATATGCACGAATCTTCT
GGGCTAACTGAGCAGATCCGAGAATCCGCGGTCACGCTCAAAGAAGCCGAAGATGCCGTGCTCGCATTAATTGAGAAGCA
CTGCGATCCAGCCCATCCTGCACCGCTAGCTGGTAACTCCATTGCCACTGACCGCGCGTTTATCCGCGAACAGATGCCAC
GTCTTGATGAGGCCCTGCATTACCGCATGGTGGATGTGTCCTCGGTGAAGGAATTGGCGCGTCGCTGGTACCCACGCGTG
TACTACAAGCAGCCGGAAAAGGGTTTGGCGCACCGCGCGTTGGCGGACATTGTGGAATCGATTCGGGAGTTGGATTACTA
CCGTCGCTCATTTTTTGTTGCAGAGCCTGGTCCTACCTCTGAGCAGTGCGCGGATGATGCGCAGGCAGCGGTGGACCGTT
TCGCACCCTACTTTGATTAG

Upstream 100 bases:

>100_bases
GCTGTCCAAGGCCATGAATTTTGTGTCCTCTGTTGCTCCAACCGCTGTACTCTCCCCTGTCATGGGCTGGGTTTATAAGA
AGATGGGTTAGTTTTTAAAA

Downstream 100 bases:

>100_bases
AGGGTTTTTAGCAGCCTGGTGAGTTCGGTGAGCATATGCACCCGCCACCAGGCCCAATCGTGGCCGCCATGCACGCCACG
CACGCGAACCTCGCGGATGT

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSESENNTTPAVAARDDRLVWVDLEMTGLDLKRHVIVEVAALVTDANLNVLGEGVDLVVHATEEELAQMDDFVTNMHESS
GLTEQIRESAVTLKEAEDAVLALIEKHCDPAHPAPLAGNSIATDRAFIREQMPRLDEALHYRMVDVSSVKELARRWYPRV
YYKQPEKGLAHRALADIVESIRELDYYRRSFFVAEPGPTSEQCADDAQAAVDRFAPYFD

Sequences:

>Translated_219_residues
MSESENNTTPAVAARDDRLVWVDLEMTGLDLKRHVIVEVAALVTDANLNVLGEGVDLVVHATEEELAQMDDFVTNMHESS
GLTEQIRESAVTLKEAEDAVLALIEKHCDPAHPAPLAGNSIATDRAFIREQMPRLDEALHYRMVDVSSVKELARRWYPRV
YYKQPEKGLAHRALADIVESIRELDYYRRSFFVAEPGPTSEQCADDAQAAVDRFAPYFD
>Mature_218_residues
SESENNTTPAVAARDDRLVWVDLEMTGLDLKRHVIVEVAALVTDANLNVLGEGVDLVVHATEEELAQMDDFVTNMHESSG
LTEQIRESAVTLKEAEDAVLALIEKHCDPAHPAPLAGNSIATDRAFIREQMPRLDEALHYRMVDVSSVKELARRWYPRVY
YKQPEKGLAHRALADIVESIRELDYYRRSFFVAEPGPTSEQCADDAQAAVDRFAPYFD

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=175, Percent_Identity=48, Blast_Score=182, Evalue=2e-46,
Organism=Escherichia coli, GI87082382, Length=181, Percent_Identity=47.5138121546961, Blast_Score=171, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17557752, Length=178, Percent_Identity=44.3820224719101, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6323088, Length=181, Percent_Identity=37.0165745856354, Blast_Score=123, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21355135, Length=189, Percent_Identity=43.3862433862434, Blast_Score=171, Evalue=5e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_CORGB (A4QGM5)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001139293.1
- ProteinModelPortal:   A4QGM5
- SMR:   A4QGM5
- STRING:   A4QGM5
- GeneID:   4993219
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_2384
- eggNOG:   COG1949
- HOGENOM:   HBG448545
- OMA:   ARRWYPR
- ProtClustDB:   PRK05359
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 24585; Mature: 24454

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: ACT_SITE 141-141

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESENNTTPAVAARDDRLVWVDLEMTGLDLKRHVIVEVAALVTDANLNVLGEGVDLVVH
CCCCCCCCCCEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEECCCEEEEEE
ATEEELAQMDDFVTNMHESSGLTEQIRESAVTLKEAEDAVLALIEKHCDPAHPAPLAGNS
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IATDRAFIREQMPRLDEALHYRMVDVSSVKELARRWYPRVYYKQPEKGLAHRALADIVES
CHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHH
IRELDYYRRSFFVAEPGPTSEQCADDAQAAVDRFAPYFD
HHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SESENNTTPAVAARDDRLVWVDLEMTGLDLKRHVIVEVAALVTDANLNVLGEGVDLVVH
CCCCCCCCCEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEECCCEEEEEE
ATEEELAQMDDFVTNMHESSGLTEQIRESAVTLKEAEDAVLALIEKHCDPAHPAPLAGNS
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IATDRAFIREQMPRLDEALHYRMVDVSSVKELARRWYPRVYYKQPEKGLAHRALADIVES
CHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHH
IRELDYYRRSFFVAEPGPTSEQCADDAQAAVDRFAPYFD
HHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA