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The map label for this gene is siaT [H]

Identifier: 145296392

GI number: 145296392

Start: 2540410

End: 2541726

Strand: Direct

Name: siaT [H]

Synonym: cgR_2306

Alternate gene names: 145296392

Gene position: 2540410-2541726 (Clockwise)

Preceding gene: 145296391

Following gene: 145296396

Centisome position: 76.65

GC content: 49.05

Gene sequence:

>1317_bases
ATGGAATGGTATATCTTCCTGCCAATCTACATTTTGGCACTCATCGTTGTTCTCCTTCTCAGGATTCCTGTCGCTTTCGG
CATCTTTGGTGTCGGTATCGTTGCATCACTGATTATCTTCGGAGATATCGAAACAACATCTCGCCTGATCAGCCTTAGTG
TTCTCAGCTCTGTCAACAGTTTCACTTTTACTGCGATCCCCCTTTTCATCCTCATGGGTGAAGTGCTATTCCGCTCGAGA
ATTGCACAAGACGCCATCGTTGAGATTTCAAAGATGCTTCATCGAGTTCCTGGACGCTTACCGATGGTTGCTGTTGCAGG
CGGCAGTGCGTTCGGGCTACTTTCCGGCTCGTCTCTGGCTAACACTGCACTGTTGAGCCGTACTCTGCTTCCCCAAATGA
AGAAAGCTGGATATAGCACTCACATTTCTGCTGGTTCAATCCTTGCAGCTGGTGGCCTTGCCATGGTGTTCCCTCCCAGC
GCTCTTGCTATCCTCTGGGGCGGTGTTGCCAATGTTTCCATCGGTCCTCTTCTGATTGCTGGAATCGTGCCGGGTGTCAT
GATGGCGATTGGATATGTCATCCTCATTCTTTGGCACAGCAAGAAAAAGGGTGATCCTGGGGCAGCCACCTCAGATGAGC
ATCGCCCACTTGCAGAAACCTTCCGAGGCATCGCTAAGAACCTGCTTCTTCCCGGAGTTCTCGCATTGACAGTACTCGTC
ATTATCTTCACTGGCATTGCAACCCCCACTGAAGCTGCCGCTTTCGGCGCTGTCGCTGCTATTATCATCGCGTTTGGAGC
TGGCCGGTTCAGCTTCCGTGATCTTCTCGGTGCAAGTATGAGCAGTGTTCGCATTACTGGAACTATTTTTATTCTCGTGA
TGGCATCTACCCTTTATTCCCAGATCATGGCCTATATGGGTGCAACGACTGGCCTTGTCTCGTGGGTTTCTTCCAGCATC
GCGAATGGCGTAATCATGCTGTTCTTGATTGTATTCCTGCTTGTTCTCTTGAGCTGTTTCATTGACCAAGCATCAATCAT
GCTCATCACTGCTCCCCTGCTCATGCCTATTGCAATGCAGTTCAGCTGGGATCCAGTATGGTTCTCCATCATCGTTCTTA
TCACTCTTCAAATCGGTAATATCTCTCCACCATTTGGTATGAGTTTGTTCGTGATGAAATCCACCGCGCCTTGGATTCCG
ATGCTCACTCTTTACAGAGCAGCGATTCCGTGGATCATTTCGGATTTGGTGGTCATTCTCATTCTGTGTATTTTCCCATC
GATTGTTCTCTTCCTACCACAGCTGATGGCAAACTAA

Upstream 100 bases:

>100_bases
TGTTTTGCTTCATGCAACGATTGTCTTCCTGTTCAAACTTATTAAGGCAGGAAAAACCGACTCATCTACTGATATTGCTA
ACAGAGAAGGAGCTTAAACA

Downstream 100 bases:

>100_bases
CCCACAACTTACTAAAAAGGCCCCGCACTTTGGACTTAAAGTGCGGGGCCTTTCTCGTATTTCTAGCGCTTGAGCTTGCG
GTAATCGAAGACCTGGTCAA

Product: hypothetical protein

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MEWYIFLPIYILALIVVLLLRIPVAFGIFGVGIVASLIIFGDIETTSRLISLSVLSSVNSFTFTAIPLFILMGEVLFRSR
IAQDAIVEISKMLHRVPGRLPMVAVAGGSAFGLLSGSSLANTALLSRTLLPQMKKAGYSTHISAGSILAAGGLAMVFPPS
ALAILWGGVANVSIGPLLIAGIVPGVMMAIGYVILILWHSKKKGDPGAATSDEHRPLAETFRGIAKNLLLPGVLALTVLV
IIFTGIATPTEAAAFGAVAAIIIAFGAGRFSFRDLLGASMSSVRITGTIFILVMASTLYSQIMAYMGATTGLVSWVSSSI
ANGVIMLFLIVFLLVLLSCFIDQASIMLITAPLLMPIAMQFSWDPVWFSIIVLITLQIGNISPPFGMSLFVMKSTAPWIP
MLTLYRAAIPWIISDLVVILILCIFPSIVLFLPQLMAN

Sequences:

>Translated_438_residues
MEWYIFLPIYILALIVVLLLRIPVAFGIFGVGIVASLIIFGDIETTSRLISLSVLSSVNSFTFTAIPLFILMGEVLFRSR
IAQDAIVEISKMLHRVPGRLPMVAVAGGSAFGLLSGSSLANTALLSRTLLPQMKKAGYSTHISAGSILAAGGLAMVFPPS
ALAILWGGVANVSIGPLLIAGIVPGVMMAIGYVILILWHSKKKGDPGAATSDEHRPLAETFRGIAKNLLLPGVLALTVLV
IIFTGIATPTEAAAFGAVAAIIIAFGAGRFSFRDLLGASMSSVRITGTIFILVMASTLYSQIMAYMGATTGLVSWVSSSI
ANGVIMLFLIVFLLVLLSCFIDQASIMLITAPLLMPIAMQFSWDPVWFSIIVLITLQIGNISPPFGMSLFVMKSTAPWIP
MLTLYRAAIPWIISDLVVILILCIFPSIVLFLPQLMAN
>Mature_438_residues
MEWYIFLPIYILALIVVLLLRIPVAFGIFGVGIVASLIIFGDIETTSRLISLSVLSSVNSFTFTAIPLFILMGEVLFRSR
IAQDAIVEISKMLHRVPGRLPMVAVAGGSAFGLLSGSSLANTALLSRTLLPQMKKAGYSTHISAGSILAAGGLAMVFPPS
ALAILWGGVANVSIGPLLIAGIVPGVMMAIGYVILILWHSKKKGDPGAATSDEHRPLAETFRGIAKNLLLPGVLALTVLV
IIFTGIATPTEAAAFGAVAAIIIAFGAGRFSFRDLLGASMSSVRITGTIFILVMASTLYSQIMAYMGATTGLVSWVSSSI
ANGVIMLFLIVFLLVLLSCFIDQASIMLITAPLLMPIAMQFSWDPVWFSIIVLITLQIGNISPPFGMSLFVMKSTAPWIP
MLTLYRAAIPWIISDLVVILILCIFPSIVLFLPQLMAN

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG4664

COG function: function code Q; TRAP-type mannitol/chloroaromatic compound transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=384, Percent_Identity=27.34375, Blast_Score=102, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 46630; Mature: 46630

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWYIFLPIYILALIVVLLLRIPVAFGIFGVGIVASLIIFGDIETTSRLISLSVLSSVNS
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
FTFTAIPLFILMGEVLFRSRIAQDAIVEISKMLHRVPGRLPMVAVAGGSAFGLLSGSSLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCCCHHH
NTALLSRTLLPQMKKAGYSTHISAGSILAAGGLAMVFPPSALAILWGGVANVSIGPLLIA
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCEEEEECCHHHHHHHCCCCCCCHHHHHHH
GIVPGVMMAIGYVILILWHSKKKGDPGAATSDEHRPLAETFRGIAKNLLLPGVLALTVLV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IIFTGIATPTEAAAFGAVAAIIIAFGAGRFSFRDLLGASMSSVRITGTIFILVMASTLYS
HHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHH
QIMAYMGATTGLVSWVSSSIANGVIMLFLIVFLLVLLSCFIDQASIMLITAPLLMPIAMQ
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FSWDPVWFSIIVLITLQIGNISPPFGMSLFVMKSTAPWIPMLTLYRAAIPWIISDLVVIL
CCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
ILCIFPSIVLFLPQLMAN
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEWYIFLPIYILALIVVLLLRIPVAFGIFGVGIVASLIIFGDIETTSRLISLSVLSSVNS
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
FTFTAIPLFILMGEVLFRSRIAQDAIVEISKMLHRVPGRLPMVAVAGGSAFGLLSGSSLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEECCCCHHH
NTALLSRTLLPQMKKAGYSTHISAGSILAAGGLAMVFPPSALAILWGGVANVSIGPLLIA
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCEEEEECCHHHHHHHCCCCCCCHHHHHHH
GIVPGVMMAIGYVILILWHSKKKGDPGAATSDEHRPLAETFRGIAKNLLLPGVLALTVLV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IIFTGIATPTEAAAFGAVAAIIIAFGAGRFSFRDLLGASMSSVRITGTIFILVMASTLYS
HHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHH
QIMAYMGATTGLVSWVSSSIANGVIMLFLIVFLLVLLSCFIDQASIMLITAPLLMPIAMQ
HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FSWDPVWFSIIVLITLQIGNISPPFGMSLFVMKSTAPWIPMLTLYRAAIPWIISDLVVIL
CCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
ILCIFPSIVLFLPQLMAN
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]