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The map label for this gene is scoA [H]

Identifier: 145296357

GI number: 145296357

Start: 2502847

End: 2503599

Strand: Reverse

Name: scoA [H]

Synonym: cgR_2272

Alternate gene names: 145296357

Gene position: 2503599-2502847 (Counterclockwise)

Preceding gene: 145296362

Following gene: 145296356

Centisome position: 75.54

GC content: 58.03

Gene sequence:

>753_bases
ATGTCTCACATGATTAACAAGAGCATTTCTTCCACTGCTGAAGCGGTGGCCGATATCCCAGACGGTGCGTCCATCGCCGT
CGGTGGTTTCGGCCTCGTGGGCATCCCCACTGCATTGATCCTCGCCCTCCGCGAACAAGGCGCAGGCGATCTGACCATCA
TTTCCAACAACCTAGGCACCGACGGTTTCGGCCTCGGACTGTTGCTTTTGGATAAGAAGATCTCCAAGTCCATCGGCTCC
TACCTTGGCTCCAACAAGGAATATGCACGCCAGTACCTGGAAGGAGAACTCACCGTCGAGTTCACCCCGCAGGGCACCTT
GGCTGAACGCCTCCGCGCAGGTGGCGCCGGCATCCCTGCGTTTTACACCACCGCAGGCGTGGGCACCCAGGTCGCAGAAG
GCGGACTCCCACAGCGCTACAACACCGACGGCACCGTCGCCGTGGTGTCCCAGCCAAAGGAAACCCGCGAATTCAACGGC
CAGCTCTACGTCATGGAAGAGGGCATCCGCGCCGATTACGCACTCGTGCACGCACACAAAGCAGATCGCTTTGGCAACCT
GGTGTTCCGCAAGACCGCGCAGAACTTCAACCCAGATGCAGCAATGAGCGGCAAGATCACCATTGCTCAGGTCGAGCACT
TTGTAGACGAACTCCACCCAGATGAGATCGATCTGCCAGGAATTTACGTCAACCGCGTCGTCCACGTTGGACCGCAGGAA
ACCGGAATCGAAAACAGGACGGTGTCTAACTAA

Upstream 100 bases:

>100_bases
AAATGATTGTACGAAATCTGGCGATTGTTCGACCATCCCATCAACTCCTCTTTTTGTTCGCATTGCGAACTCTTGTGCAT
ATGATGAACATTACGTTAGC

Downstream 100 bases:

>100_bases
TGACTTGGGATCATAACCAAATGGCAGCCCGCGTTGCCCAGGAACTTGAAGACGGCCAGTACGTCAACCTCGGCATCGGA
ATGCCGACACTTATCCCCGG

Product: hypothetical protein

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSHMINKSISSTAEAVADIPDGASIAVGGFGLVGIPTALILALREQGAGDLTIISNNLGTDGFGLGLLLLDKKISKSIGS
YLGSNKEYARQYLEGELTVEFTPQGTLAERLRAGGAGIPAFYTTAGVGTQVAEGGLPQRYNTDGTVAVVSQPKETREFNG
QLYVMEEGIRADYALVHAHKADRFGNLVFRKTAQNFNPDAAMSGKITIAQVEHFVDELHPDEIDLPGIYVNRVVHVGPQE
TGIENRTVSN

Sequences:

>Translated_250_residues
MSHMINKSISSTAEAVADIPDGASIAVGGFGLVGIPTALILALREQGAGDLTIISNNLGTDGFGLGLLLLDKKISKSIGS
YLGSNKEYARQYLEGELTVEFTPQGTLAERLRAGGAGIPAFYTTAGVGTQVAEGGLPQRYNTDGTVAVVSQPKETREFNG
QLYVMEEGIRADYALVHAHKADRFGNLVFRKTAQNFNPDAAMSGKITIAQVEHFVDELHPDEIDLPGIYVNRVVHVGPQE
TGIENRTVSN
>Mature_249_residues
SHMINKSISSTAEAVADIPDGASIAVGGFGLVGIPTALILALREQGAGDLTIISNNLGTDGFGLGLLLLDKKISKSIGSY
LGSNKEYARQYLEGELTVEFTPQGTLAERLRAGGAGIPAFYTTAGVGTQVAEGGLPQRYNTDGTVAVVSQPKETREFNGQ
LYVMEEGIRADYALVHAHKADRFGNLVFRKTAQNFNPDAAMSGKITIAQVEHFVDELHPDEIDLPGIYVNRVVHVGPQET
GIENRTVSN

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=249, Percent_Identity=53.8152610441767, Blast_Score=273, Evalue=1e-73,
Organism=Homo sapiens, GI11545841, Length=244, Percent_Identity=50, Blast_Score=236, Evalue=1e-62,
Organism=Escherichia coli, GI1788551, Length=216, Percent_Identity=38.4259259259259, Blast_Score=160, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17531517, Length=237, Percent_Identity=53.1645569620253, Blast_Score=250, Evalue=6e-67,
Organism=Drosophila melanogaster, GI21358325, Length=229, Percent_Identity=56.7685589519651, Blast_Score=259, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24655794, Length=229, Percent_Identity=56.7685589519651, Blast_Score=259, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 26630; Mature: 26499

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHMINKSISSTAEAVADIPDGASIAVGGFGLVGIPTALILALREQGAGDLTIISNNLGT
CCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCC
DGFGLGLLLLDKKISKSIGSYLGSNKEYARQYLEGELTVEFTPQGTLAERLRAGGAGIPA
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCH
FYTTAGVGTQVAEGGLPQRYNTDGTVAVVSQPKETREFNGQLYVMEEGIRADYALVHAHK
HHHHCCCCHHHHCCCCCCCCCCCCCEEEEECCHHHHHHCCEEEEEECCCCCCEEEEEEHH
ADRFGNLVFRKTAQNFNPDAAMSGKITIAQVEHFVDELHPDEIDLPGIYVNRVVHVGPQE
HHHHHCHHEEHHHCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCC
TGIENRTVSN
CCCCCCCCCC
>Mature Secondary Structure 
SHMINKSISSTAEAVADIPDGASIAVGGFGLVGIPTALILALREQGAGDLTIISNNLGT
CCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCC
DGFGLGLLLLDKKISKSIGSYLGSNKEYARQYLEGELTVEFTPQGTLAERLRAGGAGIPA
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCH
FYTTAGVGTQVAEGGLPQRYNTDGTVAVVSQPKETREFNGQLYVMEEGIRADYALVHAHK
HHHHCCCCHHHHCCCCCCCCCCCCCEEEEECCHHHHHHCCEEEEEECCCCCCEEEEEEHH
ADRFGNLVFRKTAQNFNPDAAMSGKITIAQVEHFVDELHPDEIDLPGIYVNRVVHVGPQE
HHHHHCHHEEHHHCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCC
TGIENRTVSN
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]