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The map label for this gene is ygfU [H]

Identifier: 145296326

GI number: 145296326

Start: 2471409

End: 2473388

Strand: Direct

Name: ygfU [H]

Synonym: cgR_2241

Alternate gene names: 145296326

Gene position: 2471409-2473388 (Clockwise)

Preceding gene: 145296311

Following gene: 145296328

Centisome position: 74.57

GC content: 56.26

Gene sequence:

>1980_bases
ATGGATAAATTTCATATCGAGGACGAAGGGACAACCCCGAACGCCGTGACAACATCAACCACAACCCGGGTGAAACATCC
GGTAGACCAGGTGCCACCCGCACCCAAACTTGCAGCCCTAGGGCTCCAACACGTTCTTGCTTTCTACGCAGGAGCCGTCA
TTGTTCCGCTGCTGATTGCACAGTCGCTGAACTTGGACACTGCGACCACCATTCACCTGATTAACGCTGACTTGTTGACA
TGTGGCATCGCCACGTTGATTCAGTCTGTGGGCATTGGTCGCCACATTGGTGTGCGCCTGCCGATCGTTCAAGGTGTCAC
CACTACTGCTGTTGCTCCCATCATCGCCATTGGTTTGGGCGTTACTGATGGTCAAGGTGGCGTTGCGTCGCTGCCTGCCA
TTTACGGTGCAGTCATTGTCTCCGGCATTTTCACGTTCTTTGCAGCGCCGGTGTTTGCGCGTTTCCTCAAGTTCTTCCCA
CCAGTTGTCACCGGTACTGTGCTGTTGGTTATGGGTGCTTCCCTGCTGTCGGTATCTGCAAATGACTTTGTGAACTACGC
CGATGGGGTGCCTGCTGCCCGCGATCTTGCTTACGGTTTTGGCACCTTGGCGGTGATCATTTTGGCGCAGCGCTTCTTCC
GTGGATTCATGGGCACCTTGGCTGTGTTGATCGGCCTGGTTGGTGGCACCGCAGTTGCTCTGATCTTGGGCGATGCCAAC
TTGGATGAGGTGGGAAATGCTGAAGCGTTCGACATCACCACTCCGTTTTATTTTGGTGTTCCAGAATTTAACGCTGTTGC
CATTTTCTCCATGATTATCGTCATGATCATCACCATGGTGGAGACCACCGGTGATGTGTTTGCAACGGGGGAAATCGTCG
GCAAGCGAACTCGCCGCAGTGATGTCACCCGCGCACTGCGCGCTGACGGCCTGTCCACCCTGATTGGTGGCGTCATGAAC
TCCTTCCCGTACACCTGCTTCGCGCAAAACGTTGGCTTGGTGCGCATTACTGGCGTGAAATCTCGCTGGGTTGCGGCAGC
TGCTGCCGGCTTCATGATCATCCTCGGTGTGCTGCCCAAGGCTGGCGCGATCGTCGCTTCCATCCCTTCCCCAGTCCTCG
GTGGCGCATCCTTGGCACTGTTCGCCAACGTTGCATGGGTGGGCATCCAGACCATCGCCAAGTCTGACCTCGCTGATAGC
CGCAACTCCGTCATCGTGACCTCCGCACTTGGCCTAGCCATGCTGGTGTCCTTCCGCCCCGATGTTGCTCAGGCGTTCCC
TGAGTGGGCGCGTATCTTCGTCTCCTCCGGCATGTCCGTCGGCGCGATCACCGCGATCCTACTTAACCTGCTGTTCTTCC
ATGTCGGACGCCAATCCGGTGGACAAGTCGCTACCTCAAAATCCGGTAAGCGCATCAATTTGGATGCGGTCAACAAGATG
GATCGCACCGACTTCGTAGAAACCTTCGCACCGCTGTTCAACAGCAAGACCTGGCCTTTGGAAACCGCATGGGAATCCCA
GCCATTCGCCAACGTCACGGAACTGCGCGAAGCCATCCAAGTCGCTGTGCTCACCGCACCGTTGTCCGACCGCGAAGAGC
TCATCCACGACTACCCCGACATGGCACAGCTCATTTTGGCCACCGAAGAGGAAGCCTCCACCATCTCTCAAGACCGTGGT
TCGATCGGTCTTGATGATCTCGATGACGTGGATCAAGAAAAGCTCATCACCGTCACCGAGCAGTACCGCGAACGCTTCAA
CATGCCGTATGTTGCGTACTTCGACACCATGGATTCTGTGGATACCGTCGTCGCCGCCGGCTTGCGCCGCCTCGACAACT
CCGACGAGCAGGAGCACCGCCAAGCGCTATCGGAAATCATTGAGATTGCCAATGACCGCTTCGATATTTTGCTTGCCGAC
GCTAACCCAGCCCGTTCAGCTTTCGATCGCAAGTTTACCGAGACTGACTTCCTCGGCTAA

Upstream 100 bases:

>100_bases
GTTCTTCGATCCTACCAGTGTCAACGCCTATGTGAATAACTGAAAACTAACGATCCTATCTGATTATTTTGTGCGGTGTA
GGAAAAAGTGGACAATACTG

Downstream 100 bases:

>100_bases
GACACCAAAAACAAATTAAGGCCCTGCACTTATGTGAAGTGCAGGGCCTTACCTTATTTCTAGTTCAGATCATTCGGGTG
TGAACCACCACGATCATTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 659; Mature: 659

Protein sequence:

>659_residues
MDKFHIEDEGTTPNAVTTSTTTRVKHPVDQVPPAPKLAALGLQHVLAFYAGAVIVPLLIAQSLNLDTATTIHLINADLLT
CGIATLIQSVGIGRHIGVRLPIVQGVTTTAVAPIIAIGLGVTDGQGGVASLPAIYGAVIVSGIFTFFAAPVFARFLKFFP
PVVTGTVLLVMGASLLSVSANDFVNYADGVPAARDLAYGFGTLAVIILAQRFFRGFMGTLAVLIGLVGGTAVALILGDAN
LDEVGNAEAFDITTPFYFGVPEFNAVAIFSMIIVMIITMVETTGDVFATGEIVGKRTRRSDVTRALRADGLSTLIGGVMN
SFPYTCFAQNVGLVRITGVKSRWVAAAAAGFMIILGVLPKAGAIVASIPSPVLGGASLALFANVAWVGIQTIAKSDLADS
RNSVIVTSALGLAMLVSFRPDVAQAFPEWARIFVSSGMSVGAITAILLNLLFFHVGRQSGGQVATSKSGKRINLDAVNKM
DRTDFVETFAPLFNSKTWPLETAWESQPFANVTELREAIQVAVLTAPLSDREELIHDYPDMAQLILATEEEASTISQDRG
SIGLDDLDDVDQEKLITVTEQYRERFNMPYVAYFDTMDSVDTVVAAGLRRLDNSDEQEHRQALSEIIEIANDRFDILLAD
ANPARSAFDRKFTETDFLG

Sequences:

>Translated_659_residues
MDKFHIEDEGTTPNAVTTSTTTRVKHPVDQVPPAPKLAALGLQHVLAFYAGAVIVPLLIAQSLNLDTATTIHLINADLLT
CGIATLIQSVGIGRHIGVRLPIVQGVTTTAVAPIIAIGLGVTDGQGGVASLPAIYGAVIVSGIFTFFAAPVFARFLKFFP
PVVTGTVLLVMGASLLSVSANDFVNYADGVPAARDLAYGFGTLAVIILAQRFFRGFMGTLAVLIGLVGGTAVALILGDAN
LDEVGNAEAFDITTPFYFGVPEFNAVAIFSMIIVMIITMVETTGDVFATGEIVGKRTRRSDVTRALRADGLSTLIGGVMN
SFPYTCFAQNVGLVRITGVKSRWVAAAAAGFMIILGVLPKAGAIVASIPSPVLGGASLALFANVAWVGIQTIAKSDLADS
RNSVIVTSALGLAMLVSFRPDVAQAFPEWARIFVSSGMSVGAITAILLNLLFFHVGRQSGGQVATSKSGKRINLDAVNKM
DRTDFVETFAPLFNSKTWPLETAWESQPFANVTELREAIQVAVLTAPLSDREELIHDYPDMAQLILATEEEASTISQDRG
SIGLDDLDDVDQEKLITVTEQYRERFNMPYVAYFDTMDSVDTVVAAGLRRLDNSDEQEHRQALSEIIEIANDRFDILLAD
ANPARSAFDRKFTETDFLG
>Mature_659_residues
MDKFHIEDEGTTPNAVTTSTTTRVKHPVDQVPPAPKLAALGLQHVLAFYAGAVIVPLLIAQSLNLDTATTIHLINADLLT
CGIATLIQSVGIGRHIGVRLPIVQGVTTTAVAPIIAIGLGVTDGQGGVASLPAIYGAVIVSGIFTFFAAPVFARFLKFFP
PVVTGTVLLVMGASLLSVSANDFVNYADGVPAARDLAYGFGTLAVIILAQRFFRGFMGTLAVLIGLVGGTAVALILGDAN
LDEVGNAEAFDITTPFYFGVPEFNAVAIFSMIIVMIITMVETTGDVFATGEIVGKRTRRSDVTRALRADGLSTLIGGVMN
SFPYTCFAQNVGLVRITGVKSRWVAAAAAGFMIILGVLPKAGAIVASIPSPVLGGASLALFANVAWVGIQTIAKSDLADS
RNSVIVTSALGLAMLVSFRPDVAQAFPEWARIFVSSGMSVGAITAILLNLLFFHVGRQSGGQVATSKSGKRINLDAVNKM
DRTDFVETFAPLFNSKTWPLETAWESQPFANVTELREAIQVAVLTAPLSDREELIHDYPDMAQLILATEEEASTISQDRG
SIGLDDLDDVDQEKLITVTEQYRERFNMPYVAYFDTMDSVDTVVAAGLRRLDNSDEQEHRQALSEIIEIANDRFDILLAD
ANPARSAFDRKFTETDFLG

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680145, Length=262, Percent_Identity=25.5725190839695, Blast_Score=80, Evalue=8e-15,
Organism=Homo sapiens, GI44680143, Length=262, Percent_Identity=25.5725190839695, Blast_Score=80, Evalue=9e-15,
Organism=Homo sapiens, GI44680148, Length=158, Percent_Identity=30.379746835443, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI40316845, Length=158, Percent_Identity=30.379746835443, Blast_Score=79, Evalue=2e-14,
Organism=Escherichia coli, GI87082181, Length=466, Percent_Identity=39.2703862660944, Blast_Score=311, Evalue=6e-86,
Organism=Escherichia coli, GI1790087, Length=466, Percent_Identity=29.8283261802575, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI87082178, Length=439, Percent_Identity=29.3849658314351, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788843, Length=437, Percent_Identity=27.9176201372998, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081818, Length=415, Percent_Identity=30.1204819277108, Blast_Score=110, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17558856, Length=478, Percent_Identity=24.0585774058577, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17541904, Length=440, Percent_Identity=22.0454545454545, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17542262, Length=193, Percent_Identity=26.9430051813472, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21356175, Length=443, Percent_Identity=23.2505643340858, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 70240; Mature: 70240

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKFHIEDEGTTPNAVTTSTTTRVKHPVDQVPPAPKLAALGLQHVLAFYAGAVIVPLLIA
CCCEEECCCCCCCCCEECCCHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QSLNLDTATTIHLINADLLTCGIATLIQSVGIGRHIGVRLPIVQGVTTTAVAPIIAIGLG
HHCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCEEEHHHCCCHHHHHHHHHHHHCC
VTDGQGGVASLPAIYGAVIVSGIFTFFAAPVFARFLKFFPPVVTGTVLLVMGASLLSVSA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCH
NDFVNYADGVPAARDLAYGFGTLAVIILAQRFFRGFMGTLAVLIGLVGGTAVALILGDAN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
LDEVGNAEAFDITTPFYFGVPEFNAVAIFSMIIVMIITMVETTGDVFATGEIVGKRTRRS
CCCCCCCCEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHH
DVTRALRADGLSTLIGGVMNSFPYTCFAQNVGLVRITGVKSRWVAAAAAGFMIILGVLPK
HHHHHHHHCCHHHHHHHHHHCCCCEEHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCC
AGAIVASIPSPVLGGASLALFANVAWVGIQTIAKSDLADSRNSVIVTSALGLAMLVSFRP
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCC
DVAQAFPEWARIFVSSGMSVGAITAILLNLLFFHVGRQSGGQVATSKSGKRINLDAVNKM
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEHHHHCCC
DRTDFVETFAPLFNSKTWPLETAWESQPFANVTELREAIQVAVLTAPLSDREELIHDYPD
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCHHHHHHCCHH
MAQLILATEEEASTISQDRGSIGLDDLDDVDQEKLITVTEQYRERFNMPYVAYFDTMDSV
HHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHH
DTVVAAGLRRLDNSDEQEHRQALSEIIEIANDRFDILLADANPARSAFDRKFTETDFLG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDKFHIEDEGTTPNAVTTSTTTRVKHPVDQVPPAPKLAALGLQHVLAFYAGAVIVPLLIA
CCCEEECCCCCCCCCEECCCHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QSLNLDTATTIHLINADLLTCGIATLIQSVGIGRHIGVRLPIVQGVTTTAVAPIIAIGLG
HHCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCEEEHHHCCCHHHHHHHHHHHHCC
VTDGQGGVASLPAIYGAVIVSGIFTFFAAPVFARFLKFFPPVVTGTVLLVMGASLLSVSA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCH
NDFVNYADGVPAARDLAYGFGTLAVIILAQRFFRGFMGTLAVLIGLVGGTAVALILGDAN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
LDEVGNAEAFDITTPFYFGVPEFNAVAIFSMIIVMIITMVETTGDVFATGEIVGKRTRRS
CCCCCCCCEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHH
DVTRALRADGLSTLIGGVMNSFPYTCFAQNVGLVRITGVKSRWVAAAAAGFMIILGVLPK
HHHHHHHHCCHHHHHHHHHHCCCCEEHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCC
AGAIVASIPSPVLGGASLALFANVAWVGIQTIAKSDLADSRNSVIVTSALGLAMLVSFRP
CCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCC
DVAQAFPEWARIFVSSGMSVGAITAILLNLLFFHVGRQSGGQVATSKSGKRINLDAVNKM
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEHHHHCCC
DRTDFVETFAPLFNSKTWPLETAWESQPFANVTELREAIQVAVLTAPLSDREELIHDYPD
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCHHHHHHCCHH
MAQLILATEEEASTISQDRGSIGLDDLDDVDQEKLITVTEQYRERFNMPYVAYFDTMDSV
HHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHH
DTVVAAGLRRLDNSDEQEHRQALSEIIEIANDRFDILLADANPARSAFDRKFTETDFLG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]