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The map label for this gene is rhtC [C]

Identifier: 145296312

GI number: 145296312

Start: 2457513

End: 2458184

Strand: Reverse

Name: rhtC [C]

Synonym: cgR_2227

Alternate gene names: 145296312

Gene position: 2458184-2457513 (Counterclockwise)

Preceding gene: 145296313

Following gene: 145296308

Centisome position: 74.17

GC content: 57.59

Gene sequence:

>672_bases
GTGGAGTGGACCGCTTTTGGCACCCTGATTCTGCTCAATTTGGTGGGCAGTTTATCCCCGGGGCCTGATACCTTTTTCCT
CCTCCGCTTAGCCACCCGCTCCAGAGCGCACGCGATCGCTGGCGTCGCCGGCATCGTCACCGGACTCACGGTGTGGGTGA
CGCTGACGGTCGTGGGAGCAGCGGCGCTGCTCACCACTTATCCGTCCATCCTCGGAATCATTCAGCTTGTCGGCGGCACA
TACCTAAGCTTCATGGGGTACAAGTTGCTGCGCTCGGCGTCGAGAGAGCTTATCGACGCCCGCCAGTTCCGTTTCAACGC
CGATGCCCGACCTATCCCGGATGCGGTAGAAGCACTGGGAACCCGCACTCAGGTATATCGACAAGGTTTGGCCACCAACC
TGTCAAACCCTAAAGTTGTCATGTACTTCGCGGCAATTCTGGCTCCGTTGATGCCAGCGCACCCATCACCGGTGCTGGCG
ATCTCTATCATCGTGGCGATTTTAGTGCAGACCTTTGTTACCTTCTCTGCTGTGTGCCTCATTGTCTCTACGGAGCGTGT
GCGCAAAGCAATGCTGCGTGCAGGTCCCTGGTTTGACCTGCTTGCTGGCGTTGTCTTCCTCGTTGTGGGTGTGACTCTGC
TGTATGAAGGCCTGACCGGTTTATTCGGGTAA

Upstream 100 bases:

>100_bases
GCTGGTGGTGCTGACCCATACGCTGGAACTCCAACTGCTGTTGATACCGCCAAGATGTTTGGCCGCGAGGATCTCGTAGC
TCGCTTCGAGTCATAGGCCG

Downstream 100 bases:

>100_bases
AGGCATAAAAAATGGCTTCCAATCAAAACTGATAGGAAGCCATTTTTAAAAGAGCCAAAAATTAGCCAAGCTTGTTGAAA
GCGGTAGCCATGTTGGACTT

Product: hypothetical protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MEWTAFGTLILLNLVGSLSPGPDTFFLLRLATRSRAHAIAGVAGIVTGLTVWVTLTVVGAAALLTTYPSILGIIQLVGGT
YLSFMGYKLLRSASRELIDARQFRFNADARPIPDAVEALGTRTQVYRQGLATNLSNPKVVMYFAAILAPLMPAHPSPVLA
ISIIVAILVQTFVTFSAVCLIVSTERVRKAMLRAGPWFDLLAGVVFLVVGVTLLYEGLTGLFG

Sequences:

>Translated_223_residues
MEWTAFGTLILLNLVGSLSPGPDTFFLLRLATRSRAHAIAGVAGIVTGLTVWVTLTVVGAAALLTTYPSILGIIQLVGGT
YLSFMGYKLLRSASRELIDARQFRFNADARPIPDAVEALGTRTQVYRQGLATNLSNPKVVMYFAAILAPLMPAHPSPVLA
ISIIVAILVQTFVTFSAVCLIVSTERVRKAMLRAGPWFDLLAGVVFLVVGVTLLYEGLTGLFG
>Mature_223_residues
MEWTAFGTLILLNLVGSLSPGPDTFFLLRLATRSRAHAIAGVAGIVTGLTVWVTLTVVGAAALLTTYPSILGIIQLVGGT
YLSFMGYKLLRSASRELIDARQFRFNADARPIPDAVEALGTRTQVYRQGLATNLSNPKVVMYFAAILAPLMPAHPSPVLA
ISIIVAILVQTFVTFSAVCLIVSTERVRKAMLRAGPWFDLLAGVVFLVVGVTLLYEGLTGLFG

Specific function: Conducts The Efflux Of Threonine. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=210, Percent_Identity=30.4761904761905, Blast_Score=104, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23866; Mature: 23866

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWTAFGTLILLNLVGSLSPGPDTFFLLRLATRSRAHAIAGVAGIVTGLTVWVTLTVVGA
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALLTTYPSILGIIQLVGGTYLSFMGYKLLRSASRELIDARQFRFNADARPIPDAVEALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
TRTQVYRQGLATNLSNPKVVMYFAAILAPLMPAHPSPVLAISIIVAILVQTFVTFSAVCL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IVSTERVRKAMLRAGPWFDLLAGVVFLVVGVTLLYEGLTGLFG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEWTAFGTLILLNLVGSLSPGPDTFFLLRLATRSRAHAIAGVAGIVTGLTVWVTLTVVGA
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AALLTTYPSILGIIQLVGGTYLSFMGYKLLRSASRELIDARQFRFNADARPIPDAVEALG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
TRTQVYRQGLATNLSNPKVVMYFAAILAPLMPAHPSPVLAISIIVAILVQTFVTFSAVCL
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IVSTERVRKAMLRAGPWFDLLAGVVFLVVGVTLLYEGLTGLFG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]