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The map label for this gene is dcp [H]

Identifier: 145296256

GI number: 145296256

Start: 2396453

End: 2398489

Strand: Reverse

Name: dcp [H]

Synonym: cgR_2173

Alternate gene names: 145296256

Gene position: 2398489-2396453 (Counterclockwise)

Preceding gene: 145296260

Following gene: 145296255

Centisome position: 72.37

GC content: 59.6

Gene sequence:

>2037_bases
ATGACTGTTGAACACCTGCTCAAGCCCAGCACCTTGCCCTACCAGCTGCCCGATTTCGCAGCGATCAAGGTGGCCGATTT
CCTGCCCGCCTTCGAACTCGCATTAGCCGAACACGATGCTGAAATTACAGCGATCGCTACCAATGAGGACACGCCTACCT
GGGAGAACACCATTGAGGCCCTGGAACGCGCAGGCCTGTCCCTCAACCGCGTAGCCGCCGTATTCTTCAACTTGCAGGGC
ACCGATTCCTCCCCTGAAATGGATGAAATCGCAGCCACTATCGCGCCGAAACTCTCCGCGCATTCGGATGCGATTTTCCA
CAATGCTGCGCTTTTCGCGCGCATTGAGGCCGTAGAAGCACCGGCCGACGAGGAATCGCAACGCCTGCTGTCCCACACCA
AGCGCGCTTTTCGACGTCGCGGTGCAGCACTCAACGCCGACGGCAAGGCCCGACTGAGCACCATCAACCAGCGCCTATCG
GCACTGTCCGAACAGTTCGGCCGCAATCTGCTTCAAGACACCCGCGATCTGGCTGTCAACTTTGAAGAATCTGAACTTGC
CGGTTTTAGCGAAGCCCGCATATCCGCCGCCGCTGACTACGCAGCAGCAGTTGGCACCGAAGGATACGTGGTTCCCCTAG
AACTGCCCACCGTGCAGTCAGAGCAGGCAGTATTAACCGAATCCGCCTCGCGTGCAAAGCTTTATGAAGCCTCCCAGAAG
CGTGGCGCCAGCCTGAACAAGGACGTGCTGCTCGAAACCGTGCGTCTGCGTGCTGAACGCGCCGCACTTTTAGGCTACGA
CACCCACGCCGATTACGTCATCGAAGAAGAAACCGCCGATGACGTCGCAGCCGTGCGCGCCTTGCTTTATGATCTCGCCC
CAGCCGCCTCCGCCAATGCGAAAGCCGAATACAAACTCTCCGCAGAAGAAGCAGAAGAACACGGCCAAAAAGTCGGCGCA
GCTGACTGGAGCTTCTGGGAAGCCAAAGTCCGCGCCCGCGACTACGCCCTGGACGAAACCGAACTGCGCAACTACTTCCC
ACTGAACCAAGTACTCTGTGACGGCGTCTTCTTCGCTGCTAACCGCCTCTACGGAATCACCGTGGAACCACGCCCTGACC
TGCGCGGTTACGCCGAGGGCGTGGACGTCTGGGAAGTCCTCGATTCTGACGGCTCCGGCATCGGCCTGATCCTTACCGAC
TACTACGGCCGACCATCCAAGCGGGGCGGCGCTTGGATGTCCAGCTTTGTCGACCAATCCGAGCTGCTAGGCACCAAGCC
AGTCGTGGTCAACGTTATGGGTATTACCAAACCAACCACCGGCGAAGCACTACTCAGCCTCGATGAAGTAACCACCATCT
TCCACGAATTCGGCCACGGCCTGCACGGCTTGCTGTCCAAGGTGCGCTACCCAAGCTTCTCCGGAACCTCCGTGCCCCGC
GACTACGTAGAATTCCCCTCCCAGATCAACGAAAACTGGGCATTCGACCCTGCAGTAGTCCGCAACTACGCCCGCCACGT
GGACACCGGCGACATCATTCCAGACTCCCTGCTTGAGGCAGTGGAATCATCCCGCCAATTCGGACAAGGTTTTGCCACCT
CCGAATACTTGGCAGCATCGATTATCGACCTGGCCTGGCACTACCTGTCCGCAGCGGAAGCCGCAGCAGTCAATGACATT
GACCAATTCGAAGCCGACGCACTAGCTGCAGCAGGCCTCGACGTGGACAACATTGCACCGCGCTACCGATCCACCTACTT
CAACCACATCTTTGCTGGCGGCTACTCAGCCGGCTACTACTCCTACCTGTGGGCGGAAGCACTCGACGCCGACGGCTTCG
ACTGGTTCCGCGAAGAAGGCGCAGCCGGATCCGTGGCTTCCCTCGACGCAGCCCGCACCGCCGGCCAGAAATTCCGTGAC
CTGGTCTTATCCCGCGGCGCAGCCTCCGACTACAGCAACGCCTTCGAACAACTCCGTGGCCGTTCCAAAGACCTCGGCCC
ACTTCTGCGCCGCCGCGGTCTGGCTGGGGCAATCTAA

Upstream 100 bases:

>100_bases
AAATAATGGGGCTCGCCGGTGATGGTTCCCGCCGGGCATTCAACGGTGACGGAAGAGGTGGCAGACATGATGAAAACTCT
AGCAACTAGTATCGGTCACT

Downstream 100 bases:

>100_bases
ACAACCCGGTGTAGGCTAATAACCCATGACTGCATTCCTCGACCGGATCTCACAGCTGCTTACAACATCACCGCTGTGGA
TCCAGTCACCGATCGTCATC

Product: hypothetical protein

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 678; Mature: 677

Protein sequence:

>678_residues
MTVEHLLKPSTLPYQLPDFAAIKVADFLPAFELALAEHDAEITAIATNEDTPTWENTIEALERAGLSLNRVAAVFFNLQG
TDSSPEMDEIAATIAPKLSAHSDAIFHNAALFARIEAVEAPADEESQRLLSHTKRAFRRRGAALNADGKARLSTINQRLS
ALSEQFGRNLLQDTRDLAVNFEESELAGFSEARISAAADYAAAVGTEGYVVPLELPTVQSEQAVLTESASRAKLYEASQK
RGASLNKDVLLETVRLRAERAALLGYDTHADYVIEEETADDVAAVRALLYDLAPAASANAKAEYKLSAEEAEEHGQKVGA
ADWSFWEAKVRARDYALDETELRNYFPLNQVLCDGVFFAANRLYGITVEPRPDLRGYAEGVDVWEVLDSDGSGIGLILTD
YYGRPSKRGGAWMSSFVDQSELLGTKPVVVNVMGITKPTTGEALLSLDEVTTIFHEFGHGLHGLLSKVRYPSFSGTSVPR
DYVEFPSQINENWAFDPAVVRNYARHVDTGDIIPDSLLEAVESSRQFGQGFATSEYLAASIIDLAWHYLSAAEAAAVNDI
DQFEADALAAAGLDVDNIAPRYRSTYFNHIFAGGYSAGYYSYLWAEALDADGFDWFREEGAAGSVASLDAARTAGQKFRD
LVLSRGAASDYSNAFEQLRGRSKDLGPLLRRRGLAGAI

Sequences:

>Translated_678_residues
MTVEHLLKPSTLPYQLPDFAAIKVADFLPAFELALAEHDAEITAIATNEDTPTWENTIEALERAGLSLNRVAAVFFNLQG
TDSSPEMDEIAATIAPKLSAHSDAIFHNAALFARIEAVEAPADEESQRLLSHTKRAFRRRGAALNADGKARLSTINQRLS
ALSEQFGRNLLQDTRDLAVNFEESELAGFSEARISAAADYAAAVGTEGYVVPLELPTVQSEQAVLTESASRAKLYEASQK
RGASLNKDVLLETVRLRAERAALLGYDTHADYVIEEETADDVAAVRALLYDLAPAASANAKAEYKLSAEEAEEHGQKVGA
ADWSFWEAKVRARDYALDETELRNYFPLNQVLCDGVFFAANRLYGITVEPRPDLRGYAEGVDVWEVLDSDGSGIGLILTD
YYGRPSKRGGAWMSSFVDQSELLGTKPVVVNVMGITKPTTGEALLSLDEVTTIFHEFGHGLHGLLSKVRYPSFSGTSVPR
DYVEFPSQINENWAFDPAVVRNYARHVDTGDIIPDSLLEAVESSRQFGQGFATSEYLAASIIDLAWHYLSAAEAAAVNDI
DQFEADALAAAGLDVDNIAPRYRSTYFNHIFAGGYSAGYYSYLWAEALDADGFDWFREEGAAGSVASLDAARTAGQKFRD
LVLSRGAASDYSNAFEQLRGRSKDLGPLLRRRGLAGAI
>Mature_677_residues
TVEHLLKPSTLPYQLPDFAAIKVADFLPAFELALAEHDAEITAIATNEDTPTWENTIEALERAGLSLNRVAAVFFNLQGT
DSSPEMDEIAATIAPKLSAHSDAIFHNAALFARIEAVEAPADEESQRLLSHTKRAFRRRGAALNADGKARLSTINQRLSA
LSEQFGRNLLQDTRDLAVNFEESELAGFSEARISAAADYAAAVGTEGYVVPLELPTVQSEQAVLTESASRAKLYEASQKR
GASLNKDVLLETVRLRAERAALLGYDTHADYVIEEETADDVAAVRALLYDLAPAASANAKAEYKLSAEEAEEHGQKVGAA
DWSFWEAKVRARDYALDETELRNYFPLNQVLCDGVFFAANRLYGITVEPRPDLRGYAEGVDVWEVLDSDGSGIGLILTDY
YGRPSKRGGAWMSSFVDQSELLGTKPVVVNVMGITKPTTGEALLSLDEVTTIFHEFGHGLHGLLSKVRYPSFSGTSVPRD
YVEFPSQINENWAFDPAVVRNYARHVDTGDIIPDSLLEAVESSRQFGQGFATSEYLAASIIDLAWHYLSAAEAAAVNDID
QFEADALAAAGLDVDNIAPRYRSTYFNHIFAGGYSAGYYSYLWAEALDADGFDWFREEGAAGSVASLDAARTAGQKFRDL
VLSRGAASDYSNAFEQLRGRSKDLGPLLRRRGLAGAI

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=566, Percent_Identity=30.2120141342756, Blast_Score=210, Evalue=3e-54,
Organism=Homo sapiens, GI14149738, Length=644, Percent_Identity=27.1739130434783, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI156105687, Length=633, Percent_Identity=22.7488151658768, Blast_Score=109, Evalue=8e-24,
Organism=Escherichia coli, GI1787819, Length=690, Percent_Identity=39.7101449275362, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI1789913, Length=692, Percent_Identity=30.635838150289, Blast_Score=288, Evalue=8e-79,
Organism=Caenorhabditis elegans, GI32565901, Length=502, Percent_Identity=22.1115537848606, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319793, Length=658, Percent_Identity=24.468085106383, Blast_Score=176, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6322715, Length=579, Percent_Identity=22.9706390328152, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21356111, Length=455, Percent_Identity=24.6153846153846, Blast_Score=136, Evalue=6e-32,
Organism=Drosophila melanogaster, GI20129717, Length=417, Percent_Identity=27.5779376498801, Blast_Score=122, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 73905; Mature: 73773

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVEHLLKPSTLPYQLPDFAAIKVADFLPAFELALAEHDAEITAIATNEDTPTWENTIEA
CCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
LERAGLSLNRVAAVFFNLQGTDSSPEMDEIAATIAPKLSAHSDAIFHNAALFARIEAVEA
HHHCCCCHHHEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
PADEESQRLLSHTKRAFRRRGAALNADGKARLSTINQRLSALSEQFGRNLLQDTRDLAVN
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
FEESELAGFSEARISAAADYAAAVGTEGYVVPLELPTVQSEQAVLTESASRAKLYEASQK
CCHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHCHHHHHHHHHHHH
RGASLNKDVLLETVRLRAERAALLGYDTHADYVIEEETADDVAAVRALLYDLAPAASANA
CCCCCCHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCC
KAEYKLSAEEAEEHGQKVGAADWSFWEAKVRARDYALDETELRNYFPLNQVLCDGVFFAA
CCEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHH
NRLYGITVEPRPDLRGYAEGVDVWEVLDSDGSGIGLILTDYYGRPSKRGGAWMSSFVDQS
CCEEEEEECCCCCCCHHHCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
ELLGTKPVVVNVMGITKPTTGEALLSLDEVTTIFHEFGHGLHGLLSKVRYPSFSGTSVPR
HHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCH
DYVEFPSQINENWAFDPAVVRNYARHVDTGDIIPDSLLEAVESSRQFGQGFATSEYLAAS
HHHHCHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
IIDLAWHYLSAAEAAAVNDIDQFEADALAAAGLDVDNIAPRYRSTYFNHIFAGGYSAGYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCCCCHHH
SYLWAEALDADGFDWFREEGAAGSVASLDAARTAGQKFRDLVLSRGAASDYSNAFEQLRG
HHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
RSKDLGPLLRRRGLAGAI
CCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVEHLLKPSTLPYQLPDFAAIKVADFLPAFELALAEHDAEITAIATNEDTPTWENTIEA
CHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
LERAGLSLNRVAAVFFNLQGTDSSPEMDEIAATIAPKLSAHSDAIFHNAALFARIEAVEA
HHHCCCCHHHEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
PADEESQRLLSHTKRAFRRRGAALNADGKARLSTINQRLSALSEQFGRNLLQDTRDLAVN
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEC
FEESELAGFSEARISAAADYAAAVGTEGYVVPLELPTVQSEQAVLTESASRAKLYEASQK
CCHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHCHHHHHHHHHHHH
RGASLNKDVLLETVRLRAERAALLGYDTHADYVIEEETADDVAAVRALLYDLAPAASANA
CCCCCCHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCC
KAEYKLSAEEAEEHGQKVGAADWSFWEAKVRARDYALDETELRNYFPLNQVLCDGVFFAA
CCEEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHH
NRLYGITVEPRPDLRGYAEGVDVWEVLDSDGSGIGLILTDYYGRPSKRGGAWMSSFVDQS
CCEEEEEECCCCCCCHHHCCCHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
ELLGTKPVVVNVMGITKPTTGEALLSLDEVTTIFHEFGHGLHGLLSKVRYPSFSGTSVPR
HHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCH
DYVEFPSQINENWAFDPAVVRNYARHVDTGDIIPDSLLEAVESSRQFGQGFATSEYLAAS
HHHHCHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
IIDLAWHYLSAAEAAAVNDIDQFEADALAAAGLDVDNIAPRYRSTYFNHIFAGGYSAGYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCCCCHHH
SYLWAEALDADGFDWFREEGAAGSVASLDAARTAGQKFRDLVLSRGAASDYSNAFEQLRG
HHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
RSKDLGPLLRRRGLAGAI
CCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1537804; 11677609 [H]