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The map label for this gene is idsA [H]

Identifier: 145296134

GI number: 145296134

Start: 2263530

End: 2264630

Strand: Direct

Name: idsA [H]

Synonym: cgR_2054

Alternate gene names: 145296134

Gene position: 2263530-2264630 (Clockwise)

Preceding gene: 145296132

Following gene: 145296135

Centisome position: 68.3

GC content: 54.95

Gene sequence:

>1101_bases
TTGAGCAGTTTCGATGCCCATGACCTTGACCTCGACAAATTTCCGGAGGTCGTGCGAGATCGTTTGACGCAGTTCCTCGA
TGCTCAAGAGCTAACAATTGCTGGTATCGGCGCTCCTGTCACAGATGCTGTGGCCCATCTTCGCAGTTTCGTGCTCAATG
GAGGAAAGCGAATCCGTCCTCTTTATGCGTGGGCTGGTTTCCTGGCGGCGCAAGGCCTTAAGAATTCTTCTGAAAGACTT
GAGTCCGTCCTTGACGCCGCAGCGAGTCTCGAATTCATCCAGGCTTGTGCCTTGATTCATGACGATATTATCGATTCTTC
TGATACCCGGCGGGGAGCCCCCACAGTTCACCGGGCCGTGGAAGCTGATCACCGCGCCAATAATTTCGAAGGCGATCCCG
AGCACTTTGGCGTTTCAGTCTCAATTTTGGCTGGCGATATGGCATTGGTGTGGGCAGAAGACATGCTGCAGGATTCCGGT
TTGAGTGCAGAGGCATTGGCCCGCACGAGGGATGCTTGGCGTGGCATGCGTACTGAGGTTATTGGCGGCCAGCTGCTTGA
TATTTATCTAGAGTCGCACGCCAACGAGTCGGTGGAGCTTGCGGATTCTGTCAACCGCTTCAAAACGGCCGCTTACACGA
TTGCGCGCCCATTGCACCTGGGCGCCTCCATTGCTGGCGGTTCGCCGCAGCTTATCGACGCGCTCCTCCACTACGGCCAC
GACATCGGCATTGCATTCCAGTTGAGGGATGATCTGCTTGGTGTGTTTGGGGATCCCGCTATCACCGGCAAACCAGCTGG
AGACGATATCCGTGAAGGCAAGCGCACTGTTCTTCTTGCGCTCGCTCTACAACGCGCTGATAAGCAATCTCCTGAAGCTG
CAACGGCCATTCGCGCAGGTGTTGGAAAGGTGACTTCACCAGAAGATATTGCTGTCATTGCAGAGCATATTCGAGCTACT
GGTGCTGAAGAAGAAGTTGAGCAGCGAATTTCCCAGCTGACTGAATCCGGTTTGGCTCACCTCGATGATGTAGACATCCC
CGATGAGGTGCGCGCACAGTTGCGGGCACTGGCTATCCGCTCAACCGAACGTCGGATGTAG

Upstream 100 bases:

>100_bases
CTTAGTGTGATGAAAGTGTTTTGTTGGGACTGCCTCTGGCATTTATTCACCCCCACCAAAATTCAGCCCGCATCCCCCTA
TTCGATTGAAGGACGTCTCC

Downstream 100 bases:

>100_bases
TAGACGCGTATGACACTTTTTCAACGTTTAACCAACCCTGTAGTGCTCGGCGGCCTAGCAGGTGTTTTGCTTCTGCTCGG
CTCTTTCGGTGGCGGTGCCA

Product: hypothetical protein

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSSFDAHDLDLDKFPEVVRDRLTQFLDAQELTIAGIGAPVTDAVAHLRSFVLNGGKRIRPLYAWAGFLAAQGLKNSSERL
ESVLDAAASLEFIQACALIHDDIIDSSDTRRGAPTVHRAVEADHRANNFEGDPEHFGVSVSILAGDMALVWAEDMLQDSG
LSAEALARTRDAWRGMRTEVIGGQLLDIYLESHANESVELADSVNRFKTAAYTIARPLHLGASIAGGSPQLIDALLHYGH
DIGIAFQLRDDLLGVFGDPAITGKPAGDDIREGKRTVLLALALQRADKQSPEAATAIRAGVGKVTSPEDIAVIAEHIRAT
GAEEEVEQRISQLTESGLAHLDDVDIPDEVRAQLRALAIRSTERRM

Sequences:

>Translated_366_residues
MSSFDAHDLDLDKFPEVVRDRLTQFLDAQELTIAGIGAPVTDAVAHLRSFVLNGGKRIRPLYAWAGFLAAQGLKNSSERL
ESVLDAAASLEFIQACALIHDDIIDSSDTRRGAPTVHRAVEADHRANNFEGDPEHFGVSVSILAGDMALVWAEDMLQDSG
LSAEALARTRDAWRGMRTEVIGGQLLDIYLESHANESVELADSVNRFKTAAYTIARPLHLGASIAGGSPQLIDALLHYGH
DIGIAFQLRDDLLGVFGDPAITGKPAGDDIREGKRTVLLALALQRADKQSPEAATAIRAGVGKVTSPEDIAVIAEHIRAT
GAEEEVEQRISQLTESGLAHLDDVDIPDEVRAQLRALAIRSTERRM
>Mature_365_residues
SSFDAHDLDLDKFPEVVRDRLTQFLDAQELTIAGIGAPVTDAVAHLRSFVLNGGKRIRPLYAWAGFLAAQGLKNSSERLE
SVLDAAASLEFIQACALIHDDIIDSSDTRRGAPTVHRAVEADHRANNFEGDPEHFGVSVSILAGDMALVWAEDMLQDSGL
SAEALARTRDAWRGMRTEVIGGQLLDIYLESHANESVELADSVNRFKTAAYTIARPLHLGASIAGGSPQLIDALLHYGHD
IGIAFQLRDDLLGVFGDPAITGKPAGDDIREGKRTVLLALALQRADKQSPEAATAIRAGVGKVTSPEDIAVIAEHIRATG
AEEEVEQRISQLTESGLAHLDDVDIPDEVRAQLRALAIRSTERRM

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=260, Percent_Identity=26.9230769230769, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789578, Length=296, Percent_Identity=30.4054054054054, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786623, Length=289, Percent_Identity=31.4878892733564, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17508563, Length=296, Percent_Identity=30.7432432432432, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24651612, Length=293, Percent_Identity=26.962457337884, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 39531; Mature: 39400

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFDAHDLDLDKFPEVVRDRLTQFLDAQELTIAGIGAPVTDAVAHLRSFVLNGGKRIRP
CCCCCCCCCCHHHHHHHHHHHHHHHHCHHHEEEEECCCCHHHHHHHHHHHHHCCCCHHHH
LYAWAGFLAAQGLKNSSERLESVLDAAASLEFIQACALIHDDIIDSSDTRRGAPTVHRAV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
EADHRANNFEGDPEHFGVSVSILAGDMALVWAEDMLQDSGLSAEALARTRDAWRGMRTEV
HHHHCCCCCCCCHHHHCEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IGGQLLDIYLESHANESVELADSVNRFKTAAYTIARPLHLGASIAGGSPQLIDALLHYGH
HCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
DIGIAFQLRDDLLGVFGDPAITGKPAGDDIREGKRTVLLALALQRADKQSPEAATAIRAG
CCEEEEEEHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
VGKVTSPEDIAVIAEHIRATGAEEEVEQRISQLTESGLAHLDDVDIPDEVRAQLRALAIR
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
STERRM
HHHCCC
>Mature Secondary Structure 
SSFDAHDLDLDKFPEVVRDRLTQFLDAQELTIAGIGAPVTDAVAHLRSFVLNGGKRIRP
CCCCCCCCCHHHHHHHHHHHHHHHHCHHHEEEEECCCCHHHHHHHHHHHHHCCCCHHHH
LYAWAGFLAAQGLKNSSERLESVLDAAASLEFIQACALIHDDIIDSSDTRRGAPTVHRAV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
EADHRANNFEGDPEHFGVSVSILAGDMALVWAEDMLQDSGLSAEALARTRDAWRGMRTEV
HHHHCCCCCCCCHHHHCEEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IGGQLLDIYLESHANESVELADSVNRFKTAAYTIARPLHLGASIAGGSPQLIDALLHYGH
HCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
DIGIAFQLRDDLLGVFGDPAITGKPAGDDIREGKRTVLLALALQRADKQSPEAATAIRAG
CCEEEEEEHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
VGKVTSPEDIAVIAEHIRATGAEEEVEQRISQLTESGLAHLDDVDIPDEVRAQLRALAIR
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
STERRM
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]