| Definition | Corynebacterium glutamicum R chromosome, complete genome. |
|---|---|
| Accession | NC_009342 |
| Length | 3,314,179 |
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The map label for this gene is ftsI [H]
Identifier: 145296126
GI number: 145296126
Start: 2255201
End: 2257156
Strand: Reverse
Name: ftsI [H]
Synonym: cgR_2046
Alternate gene names: 145296126
Gene position: 2257156-2255201 (Counterclockwise)
Preceding gene: 145296127
Following gene: 145296125
Centisome position: 68.11
GC content: 53.73
Gene sequence:
>1956_bases GTGACCTACCGGCCTAAATCTTCAACCCAGGGCGGCGCACGCAAGCGACGTGTGAACATGGTTACCGCTATCGCATTGGT CATCGCTGGCGTACTGATCATTCGCCTCGGCTGGGTCCAAGTTGTCTGGGGACCAGAACTGTCCCTCAATGCTTCGGAAC AGCGCACCCGCGTGTACGTAGATCCTGCACGCCGTGGAACCATCGTGGACCGCGAAGGAAACCAGATGGCGTACACGATG CAGGCACGTTCGCTGACGGTTTCTCCGAACATCATGCGTGAGGAATTAAAGACCGGAACGGATCTGGCCTTGCGTTTGGC GGCTGAAGAAACCGATCCGGAAAACGTGGCCAGCTATGTGACCATCGAAGAAGGCAACGCGTATGTTTTTGCGTCTGAAG AACAGCGCGAAACCATTCTGTCCGACAAGGTAGAAGAGCGCATTCAAAGCATTGCGGATCGGATCCCTGAGATCATCAAA TCCCATGACCAAGATGTCACTGGAATTTCCTCTGACGAGATCCTGGACAAGCTCAATGCTGATAGCCAGTATGAGGTGCT CGTCCGCAATGTTGATCCCGATGTAGCGTCAGAAATCACCGATGAGATGCCCAGCGTCGCAGCTGATCATCAAGACATCC GCCAATACCCAAACGGCGCGATTGGTGAAAACATCATCGGTCGAATCAGCATGGACGGCGAAGGCCAGTTCGGCTTTGAG GCTTCCAACGATTCCCTGTTGGCAGGAAACAACGGTCGCTCAACCCAGGACATGTCCATTTTGGGACAAGCAATCCCGGG CACGTTGAGGGATCAAATTCCAGCCATTGATGGTGCCAGCGTTGAACTCACCGTTGATCTGGATCTGCAAACCTATGTGC AGCAGGCATTGGAGCAGGCGAAAGCTAACTCCGGTGCAGAAAACGCCTCCGCTGTGGTTCTTGATGCCAAGACCGCTGAG GTTTTGGCGATGGCAAACACCGATACCATCAACCCCAACGAAGACACGGGAAAGCAGATTGAGCAGGGCAAGAGCTTTGA CAATCCTTCTGTCACCCACCCCTTCGAGCCTGGTTCTGTAGCCAAGGTGATTACTGCAGCAGGCGTAATTCAAGAGGGCT TGACTACTCCAGATGAAGTGTTGCAGGTACCGGGCAGTATTGAAATGGCCGGTGTTTCTGTCGGTGATGCGTGGGACCAC GGTGTCGTTCCCTATACCACTGCAGGAATTTTTGGTAAGTCCTCGAATGTAGGCACTCTGATGCTTGCGCAGCGTCTTGG TGAAGATAAATTTGCTGATTACCTGGAACGATTTGGTGTGGGACAGTCAACGGGTATTGAGCTTCCGAGCGAATCCCAAG GCCTGCTGCCCGCACGTGAGCAGTGGTCTGGCGGTACTTTTGCTAACCTGCCCATCGGTCAGGGTATGTCGATCACCACG TTGCAAATGGCTGGAATCTACCAAGCCTTGGCCAACGATGGTGAACGCATTGAACCGCGGATCATCAAGAGCGTGACTGA TTCTGACGGAACAGTCCTAGAGCAGCCAGAACCCGATAAAATCCAGGTTGTCAGCGCTGAAGCTGCCCGCACCACGGTGG ATATGTTCAGGTCTGTCACCCAGGTTGATCCAACTGGAGTGCAACAAGGTACCGCTCCAGACGCCTCCATTGAGGGTTAT CAAATCTCAGGTAAGACAGGTACGGCGCAGAAAGTTGACCCCAACACGGGCGCGTACTCTAACTCGCAATACTGGATTAC CTTCGCGGGTATTGCACCCGCTGATGATCCTCGATTTGTTGTAGCCATCATGCTTGATGAGCCAGAACGCGGAGTTCACG GTGGTGGCGGCCAAACCGCAGCACCTTTGTTCAAAGACATCGCCACCTGGTTGCTCAACCGCGACAACATCCCACTGTCT GCAGCCACCGAACCGATCATCCTTCAAGCTCAATAA
Upstream 100 bases:
>100_bases CCGCCGTTCGGCGTATCAGGACGAAAGCAGAAGAGCCGCTAGAGAGCGCGAACTTACGCGACGCAGCGGTAAAGCTAAAG TCGTAAACCAAGAAGAAGGA
Downstream 100 bases:
>100_bases CTCAAACAGAAGTGTCTTTTGTAGAATTTCATAATCTGAACTTTTGCTTGAACTCTTTTCGGCATCACCCACGTGCCGCG TCCGAATTATTAACACCTAG
Product: hypothetical protein
Products: NA
Alternate protein names: Penicillin-binding protein 3; PBP-3; Peptidoglycan glycosyltransferase 3 [H]
Number of amino acids: Translated: 651; Mature: 650
Protein sequence:
>651_residues MTYRPKSSTQGGARKRRVNMVTAIALVIAGVLIIRLGWVQVVWGPELSLNASEQRTRVYVDPARRGTIVDREGNQMAYTM QARSLTVSPNIMREELKTGTDLALRLAAEETDPENVASYVTIEEGNAYVFASEEQRETILSDKVEERIQSIADRIPEIIK SHDQDVTGISSDEILDKLNADSQYEVLVRNVDPDVASEITDEMPSVAADHQDIRQYPNGAIGENIIGRISMDGEGQFGFE ASNDSLLAGNNGRSTQDMSILGQAIPGTLRDQIPAIDGASVELTVDLDLQTYVQQALEQAKANSGAENASAVVLDAKTAE VLAMANTDTINPNEDTGKQIEQGKSFDNPSVTHPFEPGSVAKVITAAGVIQEGLTTPDEVLQVPGSIEMAGVSVGDAWDH GVVPYTTAGIFGKSSNVGTLMLAQRLGEDKFADYLERFGVGQSTGIELPSESQGLLPAREQWSGGTFANLPIGQGMSITT LQMAGIYQALANDGERIEPRIIKSVTDSDGTVLEQPEPDKIQVVSAEAARTTVDMFRSVTQVDPTGVQQGTAPDASIEGY QISGKTGTAQKVDPNTGAYSNSQYWITFAGIAPADDPRFVVAIMLDEPERGVHGGGGQTAAPLFKDIATWLLNRDNIPLS AATEPIILQAQ
Sequences:
>Translated_651_residues MTYRPKSSTQGGARKRRVNMVTAIALVIAGVLIIRLGWVQVVWGPELSLNASEQRTRVYVDPARRGTIVDREGNQMAYTM QARSLTVSPNIMREELKTGTDLALRLAAEETDPENVASYVTIEEGNAYVFASEEQRETILSDKVEERIQSIADRIPEIIK SHDQDVTGISSDEILDKLNADSQYEVLVRNVDPDVASEITDEMPSVAADHQDIRQYPNGAIGENIIGRISMDGEGQFGFE ASNDSLLAGNNGRSTQDMSILGQAIPGTLRDQIPAIDGASVELTVDLDLQTYVQQALEQAKANSGAENASAVVLDAKTAE VLAMANTDTINPNEDTGKQIEQGKSFDNPSVTHPFEPGSVAKVITAAGVIQEGLTTPDEVLQVPGSIEMAGVSVGDAWDH GVVPYTTAGIFGKSSNVGTLMLAQRLGEDKFADYLERFGVGQSTGIELPSESQGLLPAREQWSGGTFANLPIGQGMSITT LQMAGIYQALANDGERIEPRIIKSVTDSDGTVLEQPEPDKIQVVSAEAARTTVDMFRSVTQVDPTGVQQGTAPDASIEGY QISGKTGTAQKVDPNTGAYSNSQYWITFAGIAPADDPRFVVAIMLDEPERGVHGGGGQTAAPLFKDIATWLLNRDNIPLS AATEPIILQAQ >Mature_650_residues TYRPKSSTQGGARKRRVNMVTAIALVIAGVLIIRLGWVQVVWGPELSLNASEQRTRVYVDPARRGTIVDREGNQMAYTMQ ARSLTVSPNIMREELKTGTDLALRLAAEETDPENVASYVTIEEGNAYVFASEEQRETILSDKVEERIQSIADRIPEIIKS HDQDVTGISSDEILDKLNADSQYEVLVRNVDPDVASEITDEMPSVAADHQDIRQYPNGAIGENIIGRISMDGEGQFGFEA SNDSLLAGNNGRSTQDMSILGQAIPGTLRDQIPAIDGASVELTVDLDLQTYVQQALEQAKANSGAENASAVVLDAKTAEV LAMANTDTINPNEDTGKQIEQGKSFDNPSVTHPFEPGSVAKVITAAGVIQEGLTTPDEVLQVPGSIEMAGVSVGDAWDHG VVPYTTAGIFGKSSNVGTLMLAQRLGEDKFADYLERFGVGQSTGIELPSESQGLLPAREQWSGGTFANLPIGQGMSITTL QMAGIYQALANDGERIEPRIIKSVTDSDGTVLEQPEPDKIQVVSAEAARTTVDMFRSVTQVDPTGVQQGTAPDASIEGYQ ISGKTGTAQKVDPNTGAYSNSQYWITFAGIAPADDPRFVVAIMLDEPERGVHGGGGQTAAPLFKDIATWLLNRDNIPLSA ATEPIILQAQ
Specific function: Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side. Note=The bulk of the molecule, except for the N-terminal membrane anchor region, protrudes into the periplasmic space, where it acts on murein (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786272, Length=635, Percent_Identity=28.6614173228346, Blast_Score=210, Evalue=2e-55, Organism=Escherichia coli, GI1786854, Length=678, Percent_Identity=23.3038348082596, Blast_Score=102, Evalue=6e-23,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005311 - InterPro: IPR001460 [H]
Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: =2.4.1.129 [H]
Molecular weight: Translated: 69762; Mature: 69630
Theoretical pI: Translated: 4.16; Mature: 4.16
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTYRPKSSTQGGARKRRVNMVTAIALVIAGVLIIRLGWVQVVWGPELSLNASEQRTRVYV CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEE DPARRGTIVDREGNQMAYTMQARSLTVSPNIMREELKTGTDLALRLAAEETDPENVASYV CCCCCCEEEECCCCEEEEEEEECEEEECHHHHHHHHCCCCCEEEEEECCCCCCCHHEEEE TIEEGNAYVFASEEQRETILSDKVEERIQSIADRIPEIIKSHDQDVTGISSDEILDKLNA EEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC DSQYEVLVRNVDPDVASEITDEMPSVAADHQDIRQYPNGAIGENIIGRISMDGEGQFGFE CCEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCEE ASNDSLLAGNNGRSTQDMSILGQAIPGTLRDQIPAIDGASVELTVDLDLQTYVQQALEQA CCCCCEEECCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHH KANSGAENASAVVLDAKTAEVLAMANTDTINPNEDTGKQIEQGKSFDNPSVTHPFEPGSV HCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHH AKVITAAGVIQEGLTTPDEVLQVPGSIEMAGVSVGDAWDHGVVPYTTAGIFGKSSNVGTL HHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCCCHHH MLAQRLGEDKFADYLERFGVGQSTGIELPSESQGLLPAREQWSGGTFANLPIGQGMSITT HHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCEEECCCCCCCEEEE LQMAGIYQALANDGERIEPRIIKSVTDSDGTVLEQPEPDKIQVVSAEAARTTVDMFRSVT HHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEECCCCCCCEEEEECHHHHHHHHHHHHHH QVDPTGVQQGTAPDASIEGYQISGKTGTAQKVDPNTGAYSNSQYWITFAGIAPADDPRFV HCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEE VAIMLDEPERGVHGGGGQTAAPLFKDIATWLLNRDNIPLSAATEPIILQAQ EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEC >Mature Secondary Structure TYRPKSSTQGGARKRRVNMVTAIALVIAGVLIIRLGWVQVVWGPELSLNASEQRTRVYV CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEE DPARRGTIVDREGNQMAYTMQARSLTVSPNIMREELKTGTDLALRLAAEETDPENVASYV CCCCCCEEEECCCCEEEEEEEECEEEECHHHHHHHHCCCCCEEEEEECCCCCCCHHEEEE TIEEGNAYVFASEEQRETILSDKVEERIQSIADRIPEIIKSHDQDVTGISSDEILDKLNA EEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC DSQYEVLVRNVDPDVASEITDEMPSVAADHQDIRQYPNGAIGENIIGRISMDGEGQFGFE CCEEEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCEEEEEECCCCCCCEE ASNDSLLAGNNGRSTQDMSILGQAIPGTLRDQIPAIDGASVELTVDLDLQTYVQQALEQA CCCCCEEECCCCCCCHHHHHHHHHCCCHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHH KANSGAENASAVVLDAKTAEVLAMANTDTINPNEDTGKQIEQGKSFDNPSVTHPFEPGSV HCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHH AKVITAAGVIQEGLTTPDEVLQVPGSIEMAGVSVGDAWDHGVVPYTTAGIFGKSSNVGTL HHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCCCCCCCCCEEECCCCCCCCCCHHH MLAQRLGEDKFADYLERFGVGQSTGIELPSESQGLLPAREQWSGGTFANLPIGQGMSITT HHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCCCEEECCCCCCCEEEE LQMAGIYQALANDGERIEPRIIKSVTDSDGTVLEQPEPDKIQVVSAEAARTTVDMFRSVT HHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEECCCCCCCEEEEECHHHHHHHHHHHHHH QVDPTGVQQGTAPDASIEGYQISGKTGTAQKVDPNTGAYSNSQYWITFAGIAPADDPRFV HCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEE VAIMLDEPERGVHGGGGQTAAPLFKDIATWLLNRDNIPLSAATEPIILQAQ EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]