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The map label for this gene is ileS [H]

Identifier: 145296110

GI number: 145296110

Start: 2234988

End: 2238152

Strand: Reverse

Name: ileS [H]

Synonym: cgR_2031

Alternate gene names: 145296110

Gene position: 2238152-2234988 (Counterclockwise)

Preceding gene: 145296112

Following gene: 145296109

Centisome position: 67.53

GC content: 55.61

Gene sequence:

>3165_bases
ATGTCTGAAGCCGTTGGCGGAGTTTACCCACAGGTTGACTTATCTGGTGGGTCATCCAGATTTCCAGAGATGGAAGAGAA
TGTACTGAGCTACTGGAAGAAGGATGACACCTTCCAGGCGAGCATCGATCAGCGCGATGGTGCTGAAGACTACGTCTTTT
ACGATGGACCTCCTTTTGCAAACGGTCTGCCACACTACGGCCACCTACTGACTGGTTACGTCAAGGACATTGTTCCTCGC
TACCAGACCATGCGTGGCTACCGCGTTCCTCGTGTCTTCGGTTGGGATACCCACGGTCTGCCAGCTGAACTTGAGGCTGA
AAAGCAGCTCGGCATCAAGGACAAAGGCGAGATCGAAGCCATGGGTCTTGCCAAGTTCAATGAATACTGTGCTACCTCGG
TGTTGCAGTACACCAAGGAATGGGAAGAGTACGTCACCCGCCAAGCTCGTTGGGTTGACTTTGAAAATGGCTACAAGACC
ATGGATCTTTCCTACATGGAGTCCGTAATCTGGGCATTTAAGGAACTTTACGACAAGGGCCTGATCTACCAGGGCTTCCG
CGTGTTGCCTTATTCCTGGGCAGAGCACACCCCGTTGTCCAACCAGGAAACCCGCCTGGATGACTCCTACAAGTTGCGCC
AAGACCCAACCTTGACCGTCACTTTCCCAGTGACTGGCACTGTAGAGGGAACTGACGCTAACCCTGACCTTGTTGGAGCA
CTTGCACTGGCATGGACGACCACCCCGTGGACCCTTCCGTCCAACCTTGCATTGGCAGTTAATCCAAGCGTGACCTACGC
ATTGGTTGAGGTTGCTGAAGACGGTGAGGAGGGATTCGTCGGCAAGCGTGTTCTTCTGGCTAAGGACCTCGTCGGTGCCT
ACTCCAAGGAGTTGGGTGCTGAGGCAGTGGTGGTTTCTGAGCACCCTGGTTCTGAACTGGTCGGACTGACCTACGAGCCA
ATTTTCGGTTACTTCCGTGATCAAGCGAATGCATTCCAAATCTTGGGTGCAGAGTACGTCACCACCGAAGACGGCACCGG
TATCGTCCACCAAGCACCGGCTTTCGGTGAAGACGATATGAACACCTGCAACGCTGCCGGCATTGAGCCAGTCATCCCAG
TGGACATGGACGGCAAGTTCACCGGTTTGGTTCCTGAATACCAAGGTCAGCTTGTTTTCGATGCCAACAAGGACATCATC
AAGGACTTGAAGGCTGCAGGTCGCGTGGTTCGCCACCAGACCATCGAACACTCCTACCCACACTCTTGGCGTTCCGGTGA
GCCACTGATCTACATGGCTCTGCCATCTTGGTTTGTGAATGTCACCGAAATCCGCGACCGCATGGTTGAGGTCAACCAGG
ACATCGAGTGGATGCCAGCGCACATCCGCGACGGCCAGTTCGGCAAGTGGCTAGAAGGTGCCCGCGACTGGAACATCTCC
CGTTCCCGTTACTGGGGTTCACCAATTCCAGCATGGGTCTCCGACAACGACGAATACCCACGCGTTGATGTTTATGGTTC
CCTCGATGAGCTCGAGGCTGACTTTGGCGTGCGTCCAAAGTCCCTGCACCGCCCAGATATCGATGAACTGACCCGTCCAA
ACCCAGACGATCCAACCGGAAAGTCCACCATGCGACGCGTCACCGACGTGCTCGACGTGTGGTTTGACTCCGGTTCCATG
CCGTTTGCTCAGGTGCACTACCCATTCGAGAACAAAGAGTGGTTTGATACCCACGCACCAGCAGACTTCATCGTGGAGTA
CATCGGCCAGACCCGTGGCTGGTTCTACCTGCTGCACGTGCTGTCCACCGCACTGTTTGACCGCCCAGCTTTCAAGAAGG
TTGTCGCACACGGCATCGTCTTGGGTGATGACGGACTGAAGATGTCCAAGTCCAAGGGCAACTACCCGAACGTCAACGAG
GTCTTCGACCGCGACGGCTCCGACGCCATGCGTTGGTTCCTCATGAGTTCCCCAATCCTGCGCGGCGGCAACTTGATTGT
CACCGAAAAGGGCATCCGCGAAGGTGTGCGCCAAGCACAGCTTCCAATGTGGAACGCATACTCCTTCCTGCAGCTGTACA
CCTCCAAGAAGGCAACCTGGTCAGTCGACTCCACTGACGTGCTGGACCGCTACATCCTGGCGAAGCTTCACGACTTGGTG
GCAGAGACCCAGACGGCACTCGACGGCACTGACATTGCAAAGGCTTGCGACTTGGTTCGTAACTTCTGTGATGCGTTGAC
CAACTGGTACGTGCGTCGTTCCCGCGACCGATTCTGGGCTGGTGATGAAGCACACCCAGAGGCTTTCAACACCTTGTACA
CCGTGCTGGAAACCCTCACCCGCGTAGCAGCTCCACTGCTGCCAATGACCACCGAAGTGATCTGGCGTGGACTGACCGGC
GAGCGTTCTGTGCACCTGACTGATTTCCCATCCGCTGAGTCTTTCCCAGCAGATGCTGATTTGGTTCGCACCATGGATGA
GATCCGTGGCGTGTGCTCTGCGGCTTCCTCTGTTCGTAAGGCCCACAAGCTGCGTAACCGTCTGCCACTTCCAGGCCTGA
CTGTTGCTCTTCCAGACTCTGCTCGCCTGGCAGACTTTGCTTCCATCATCCGCGATGAGGTCAACGTGAAGAACGTGGAT
CTGACCTCTGACGTAGATTCCGTGGGAACCTTCGAGGTTGTTGTTAACGCTAAGGTTGCAGGTCCTCGCTTGGGCAAGGA
CGTCCAGCGCGTGATCAAGGCTGTGAAGGCTGGCAACTACACCCGCGAAGGCGACGTCGTTGTTGCCGATGGCATCGAGC
TCAACGAGGGTGAATTCACCGAGCGTCTCGTAGCAGCAAACCCTGATTCCACCGCGCAGATCGACGGCGTGGATGGACTC
GTGGTTCTGAACATGGAAGTCACGGAAGAACTTGAAGCAGAAGGCTGGGCAGCGGACGCGATCCGTGGCCTACAGGATGC
TCGAAAGAACTCCGGCTTTGAGGTTTCTGACCGCATTTCTGTTGTCGTCAGCGTTCCTGAGGACAAGAAGGAATGGATCA
CCACTCACGCTGATCACATCGCAGCGGAAGTTTTGGCAACCTCCTTTGAGATCGTCACTGATGCTCTCGACGGCGAAACC
CACGACATTGTCGCTGGTGTGACCGCGAAGGTTACTAAGAACTAA

Upstream 100 bases:

>100_bases
ATTTAGCTCAAGCTGGGTGGTACCGCGTCCGTTTTTGGGGCGTCCCCGCAGGTAGAACGATAATTATTGTTACTTGCGTG
AAGGATGGGACCGAACACAC

Downstream 100 bases:

>100_bases
GAGTTGTTTTGTTGAGAAAGCCCGCTGCACATCGGTGTGGCGGGTTTTCTTATGCCCAGATATTGACCTTGTCACTGTGT
TAAGGCATTGAATGAGTGCC

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS [H]

Number of amino acids: Translated: 1054; Mature: 1053

Protein sequence:

>1054_residues
MSEAVGGVYPQVDLSGGSSRFPEMEENVLSYWKKDDTFQASIDQRDGAEDYVFYDGPPFANGLPHYGHLLTGYVKDIVPR
YQTMRGYRVPRVFGWDTHGLPAELEAEKQLGIKDKGEIEAMGLAKFNEYCATSVLQYTKEWEEYVTRQARWVDFENGYKT
MDLSYMESVIWAFKELYDKGLIYQGFRVLPYSWAEHTPLSNQETRLDDSYKLRQDPTLTVTFPVTGTVEGTDANPDLVGA
LALAWTTTPWTLPSNLALAVNPSVTYALVEVAEDGEEGFVGKRVLLAKDLVGAYSKELGAEAVVVSEHPGSELVGLTYEP
IFGYFRDQANAFQILGAEYVTTEDGTGIVHQAPAFGEDDMNTCNAAGIEPVIPVDMDGKFTGLVPEYQGQLVFDANKDII
KDLKAAGRVVRHQTIEHSYPHSWRSGEPLIYMALPSWFVNVTEIRDRMVEVNQDIEWMPAHIRDGQFGKWLEGARDWNIS
RSRYWGSPIPAWVSDNDEYPRVDVYGSLDELEADFGVRPKSLHRPDIDELTRPNPDDPTGKSTMRRVTDVLDVWFDSGSM
PFAQVHYPFENKEWFDTHAPADFIVEYIGQTRGWFYLLHVLSTALFDRPAFKKVVAHGIVLGDDGLKMSKSKGNYPNVNE
VFDRDGSDAMRWFLMSSPILRGGNLIVTEKGIREGVRQAQLPMWNAYSFLQLYTSKKATWSVDSTDVLDRYILAKLHDLV
AETQTALDGTDIAKACDLVRNFCDALTNWYVRRSRDRFWAGDEAHPEAFNTLYTVLETLTRVAAPLLPMTTEVIWRGLTG
ERSVHLTDFPSAESFPADADLVRTMDEIRGVCSAASSVRKAHKLRNRLPLPGLTVALPDSARLADFASIIRDEVNVKNVD
LTSDVDSVGTFEVVVNAKVAGPRLGKDVQRVIKAVKAGNYTREGDVVVADGIELNEGEFTERLVAANPDSTAQIDGVDGL
VVLNMEVTEELEAEGWAADAIRGLQDARKNSGFEVSDRISVVVSVPEDKKEWITTHADHIAAEVLATSFEIVTDALDGET
HDIVAGVTAKVTKN

Sequences:

>Translated_1054_residues
MSEAVGGVYPQVDLSGGSSRFPEMEENVLSYWKKDDTFQASIDQRDGAEDYVFYDGPPFANGLPHYGHLLTGYVKDIVPR
YQTMRGYRVPRVFGWDTHGLPAELEAEKQLGIKDKGEIEAMGLAKFNEYCATSVLQYTKEWEEYVTRQARWVDFENGYKT
MDLSYMESVIWAFKELYDKGLIYQGFRVLPYSWAEHTPLSNQETRLDDSYKLRQDPTLTVTFPVTGTVEGTDANPDLVGA
LALAWTTTPWTLPSNLALAVNPSVTYALVEVAEDGEEGFVGKRVLLAKDLVGAYSKELGAEAVVVSEHPGSELVGLTYEP
IFGYFRDQANAFQILGAEYVTTEDGTGIVHQAPAFGEDDMNTCNAAGIEPVIPVDMDGKFTGLVPEYQGQLVFDANKDII
KDLKAAGRVVRHQTIEHSYPHSWRSGEPLIYMALPSWFVNVTEIRDRMVEVNQDIEWMPAHIRDGQFGKWLEGARDWNIS
RSRYWGSPIPAWVSDNDEYPRVDVYGSLDELEADFGVRPKSLHRPDIDELTRPNPDDPTGKSTMRRVTDVLDVWFDSGSM
PFAQVHYPFENKEWFDTHAPADFIVEYIGQTRGWFYLLHVLSTALFDRPAFKKVVAHGIVLGDDGLKMSKSKGNYPNVNE
VFDRDGSDAMRWFLMSSPILRGGNLIVTEKGIREGVRQAQLPMWNAYSFLQLYTSKKATWSVDSTDVLDRYILAKLHDLV
AETQTALDGTDIAKACDLVRNFCDALTNWYVRRSRDRFWAGDEAHPEAFNTLYTVLETLTRVAAPLLPMTTEVIWRGLTG
ERSVHLTDFPSAESFPADADLVRTMDEIRGVCSAASSVRKAHKLRNRLPLPGLTVALPDSARLADFASIIRDEVNVKNVD
LTSDVDSVGTFEVVVNAKVAGPRLGKDVQRVIKAVKAGNYTREGDVVVADGIELNEGEFTERLVAANPDSTAQIDGVDGL
VVLNMEVTEELEAEGWAADAIRGLQDARKNSGFEVSDRISVVVSVPEDKKEWITTHADHIAAEVLATSFEIVTDALDGET
HDIVAGVTAKVTKN
>Mature_1053_residues
SEAVGGVYPQVDLSGGSSRFPEMEENVLSYWKKDDTFQASIDQRDGAEDYVFYDGPPFANGLPHYGHLLTGYVKDIVPRY
QTMRGYRVPRVFGWDTHGLPAELEAEKQLGIKDKGEIEAMGLAKFNEYCATSVLQYTKEWEEYVTRQARWVDFENGYKTM
DLSYMESVIWAFKELYDKGLIYQGFRVLPYSWAEHTPLSNQETRLDDSYKLRQDPTLTVTFPVTGTVEGTDANPDLVGAL
ALAWTTTPWTLPSNLALAVNPSVTYALVEVAEDGEEGFVGKRVLLAKDLVGAYSKELGAEAVVVSEHPGSELVGLTYEPI
FGYFRDQANAFQILGAEYVTTEDGTGIVHQAPAFGEDDMNTCNAAGIEPVIPVDMDGKFTGLVPEYQGQLVFDANKDIIK
DLKAAGRVVRHQTIEHSYPHSWRSGEPLIYMALPSWFVNVTEIRDRMVEVNQDIEWMPAHIRDGQFGKWLEGARDWNISR
SRYWGSPIPAWVSDNDEYPRVDVYGSLDELEADFGVRPKSLHRPDIDELTRPNPDDPTGKSTMRRVTDVLDVWFDSGSMP
FAQVHYPFENKEWFDTHAPADFIVEYIGQTRGWFYLLHVLSTALFDRPAFKKVVAHGIVLGDDGLKMSKSKGNYPNVNEV
FDRDGSDAMRWFLMSSPILRGGNLIVTEKGIREGVRQAQLPMWNAYSFLQLYTSKKATWSVDSTDVLDRYILAKLHDLVA
ETQTALDGTDIAKACDLVRNFCDALTNWYVRRSRDRFWAGDEAHPEAFNTLYTVLETLTRVAAPLLPMTTEVIWRGLTGE
RSVHLTDFPSAESFPADADLVRTMDEIRGVCSAASSVRKAHKLRNRLPLPGLTVALPDSARLADFASIIRDEVNVKNVDL
TSDVDSVGTFEVVVNAKVAGPRLGKDVQRVIKAVKAGNYTREGDVVVADGIELNEGEFTERLVAANPDSTAQIDGVDGLV
VLNMEVTEELEAEGWAADAIRGLQDARKNSGFEVSDRISVVVSVPEDKKEWITTHADHIAAEVLATSFEIVTDALDGETH
DIVAGVTAKVTKN

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI94721239, Length=1029, Percent_Identity=39.2614188532556, Blast_Score=713, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1029, Percent_Identity=39.2614188532556, Blast_Score=713, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=794, Percent_Identity=28.463476070529, Blast_Score=289, Evalue=9e-78,
Organism=Homo sapiens, GI268370297, Length=889, Percent_Identity=23.9595050618673, Blast_Score=144, Evalue=6e-34,
Organism=Homo sapiens, GI268370293, Length=889, Percent_Identity=23.9595050618673, Blast_Score=143, Evalue=7e-34,
Organism=Homo sapiens, GI268370295, Length=873, Percent_Identity=23.9404352806415, Blast_Score=140, Evalue=7e-33,
Organism=Homo sapiens, GI5454158, Length=821, Percent_Identity=23.020706455542, Blast_Score=128, Evalue=3e-29,
Organism=Escherichia coli, GI2367096, Length=806, Percent_Identity=28.9081885856079, Blast_Score=301, Evalue=1e-82,
Organism=Escherichia coli, GI1790708, Length=909, Percent_Identity=23.4323432343234, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI1786861, Length=190, Percent_Identity=27.3684210526316, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17541896, Length=1029, Percent_Identity=39.2614188532556, Blast_Score=688, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=808, Percent_Identity=26.8564356435644, Blast_Score=230, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI72001587, Length=884, Percent_Identity=24.2081447963801, Blast_Score=142, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17510661, Length=526, Percent_Identity=24.3346007604563, Blast_Score=110, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1053, Percent_Identity=38.7464387464387, Blast_Score=700, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325217, Length=800, Percent_Identity=26.25, Blast_Score=238, Evalue=4e-63,
Organism=Saccharomyces cerevisiae, GI6321531, Length=809, Percent_Identity=24.4746600741656, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI28574730, Length=1075, Percent_Identity=38.046511627907, Blast_Score=679, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1075, Percent_Identity=38.046511627907, Blast_Score=679, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1075, Percent_Identity=38.046511627907, Blast_Score=679, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=765, Percent_Identity=27.3202614379085, Blast_Score=256, Evalue=6e-68,
Organism=Drosophila melanogaster, GI17864482, Length=911, Percent_Identity=23.2711306256861, Blast_Score=149, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24653289, Length=911, Percent_Identity=23.2711306256861, Blast_Score=149, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21355675, Length=650, Percent_Identity=24.4615384615385, Blast_Score=130, Evalue=5e-30,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008 [H]

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]

EC number: =6.1.1.5 [H]

Molecular weight: Translated: 117603; Mature: 117472

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAVGGVYPQVDLSGGSSRFPEMEENVLSYWKKDDTFQASIDQRDGAEDYVFYDGPPFA
CCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEECCCCCC
NGLPHYGHLLTGYVKDIVPRYQTMRGYRVPRVFGWDTHGLPAELEAEKQLGIKDKGEIEA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCHHHHCCCCCCCCEEE
MGLAKFNEYCATSVLQYTKEWEEYVTRQARWVDFENGYKTMDLSYMESVIWAFKELYDKG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEECHHHHHHHHHHHHHHHHCC
LIYQGFRVLPYSWAEHTPLSNQETRLDDSYKLRQDPTLTVTFPVTGTVEGTDANPDLVGA
CEECCCEECCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEEEEEEEECCCCCCCHHHHH
LALAWTTTPWTLPSNLALAVNPSVTYALVEVAEDGEEGFVGKRVLLAKDLVGAYSKELGA
HHHEEECCCCCCCCCCEEEECCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCC
EAVVVSEHPGSELVGLTYEPIFGYFRDQANAFQILGAEYVTTEDGTGIVHQAPAFGEDDM
CEEEEECCCCCCEEEEEHHHHHHHHHCCCCEEEEECCEEEECCCCCCEEECCCCCCCCCC
NTCNAAGIEPVIPVDMDGKFTGLVPEYQGQLVFDANKDIIKDLKAAGRVVRHQTIEHSYP
CCCCCCCCCCEEEECCCCCEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCC
HSWRSGEPLIYMALPSWFVNVTEIRDRMVEVNQDIEWMPAHIRDGQFGKWLEGARDWNIS
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCC
RSRYWGSPIPAWVSDNDEYPRVDVYGSLDELEADFGVRPKSLHRPDIDELTRPNPDDPTG
HHHCCCCCCCCCCCCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCC
KSTMRRVTDVLDVWFDSGSMPFAQVHYPFENKEWFDTHAPADFIVEYIGQTRGWFYLLHV
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
LSTALFDRPAFKKVVAHGIVLGDDGLKMSKSKGNYPNVNEVFDRDGSDAMRWFLMSSPIL
HHHHHHCCHHHHHHHHCCEEECCCCCEECCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCC
RGGNLIVTEKGIREGVRQAQLPMWNAYSFLQLYTSKKATWSVDSTDVLDRYILAKLHDLV
CCCCEEEECHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHH
AETQTALDGTDIAKACDLVRNFCDALTNWYVRRSRDRFWAGDEAHPEAFNTLYTVLETLT
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
RVAAPLLPMTTEVIWRGLTGERSVHLTDFPSAESFPADADLVRTMDEIRGVCSAASSVRK
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AHKLRNRLPLPGLTVALPDSARLADFASIIRDEVNVKNVDLTSDVDSVGTFEVVVNAKVA
HHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCEEEEEEEEECC
GPRLGKDVQRVIKAVKAGNYTREGDVVVADGIELNEGEFTERLVAANPDSTAQIDGVDGL
CCCCCHHHHHHHHHHHCCCCCCCCCEEEECCEECCCCHHHHHHHCCCCCCCEEECCCCCE
VVLNMEVTEELEAEGWAADAIRGLQDARKNSGFEVSDRISVVVSVPEDKKEWITTHADHI
EEEEEHHHHHHHCCCCHHHHHHHHHHHHHCCCCEECCCEEEEEECCCCHHHHHHHHHHHH
AAEVLATSFEIVTDALDGETHDIVAGVTAKVTKN
HHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECC
>Mature Secondary Structure 
SEAVGGVYPQVDLSGGSSRFPEMEENVLSYWKKDDTFQASIDQRDGAEDYVFYDGPPFA
CCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEECCCCCC
NGLPHYGHLLTGYVKDIVPRYQTMRGYRVPRVFGWDTHGLPAELEAEKQLGIKDKGEIEA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCHHHHCCCCCCCCEEE
MGLAKFNEYCATSVLQYTKEWEEYVTRQARWVDFENGYKTMDLSYMESVIWAFKELYDKG
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEECHHHHHHHHHHHHHHHHCC
LIYQGFRVLPYSWAEHTPLSNQETRLDDSYKLRQDPTLTVTFPVTGTVEGTDANPDLVGA
CEECCCEECCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEEEEEEEECCCCCCCHHHHH
LALAWTTTPWTLPSNLALAVNPSVTYALVEVAEDGEEGFVGKRVLLAKDLVGAYSKELGA
HHHEEECCCCCCCCCCEEEECCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCC
EAVVVSEHPGSELVGLTYEPIFGYFRDQANAFQILGAEYVTTEDGTGIVHQAPAFGEDDM
CEEEEECCCCCCEEEEEHHHHHHHHHCCCCEEEEECCEEEECCCCCCEEECCCCCCCCCC
NTCNAAGIEPVIPVDMDGKFTGLVPEYQGQLVFDANKDIIKDLKAAGRVVRHQTIEHSYP
CCCCCCCCCCEEEECCCCCEECCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCC
HSWRSGEPLIYMALPSWFVNVTEIRDRMVEVNQDIEWMPAHIRDGQFGKWLEGARDWNIS
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCCC
RSRYWGSPIPAWVSDNDEYPRVDVYGSLDELEADFGVRPKSLHRPDIDELTRPNPDDPTG
HHHCCCCCCCCCCCCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCC
KSTMRRVTDVLDVWFDSGSMPFAQVHYPFENKEWFDTHAPADFIVEYIGQTRGWFYLLHV
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHH
LSTALFDRPAFKKVVAHGIVLGDDGLKMSKSKGNYPNVNEVFDRDGSDAMRWFLMSSPIL
HHHHHHCCHHHHHHHHCCEEECCCCCEECCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCC
RGGNLIVTEKGIREGVRQAQLPMWNAYSFLQLYTSKKATWSVDSTDVLDRYILAKLHDLV
CCCCEEEECHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHH
AETQTALDGTDIAKACDLVRNFCDALTNWYVRRSRDRFWAGDEAHPEAFNTLYTVLETLT
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
RVAAPLLPMTTEVIWRGLTGERSVHLTDFPSAESFPADADLVRTMDEIRGVCSAASSVRK
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AHKLRNRLPLPGLTVALPDSARLADFASIIRDEVNVKNVDLTSDVDSVGTFEVVVNAKVA
HHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCEEEEEEEEECC
GPRLGKDVQRVIKAVKAGNYTREGDVVVADGIELNEGEFTERLVAANPDSTAQIDGVDGL
CCCCCHHHHHHHHHHHCCCCCCCCCEEEECCEECCCCHHHHHHHCCCCCCCEEECCCCCE
VVLNMEVTEELEAEGWAADAIRGLQDARKNSGFEVSDRISVVVSVPEDKKEWITTHADHI
EEEEEHHHHHHHCCCCHHHHHHHHHHHHHCCCCEECCCEEEEEECCCCHHHHHHHHHHHH
AAEVLATSFEIVTDALDGETHDIVAGVTAKVTKN
HHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]