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The map label for this gene is hmrR [H]

Identifier: 145296108

GI number: 145296108

Start: 2233824

End: 2234264

Strand: Reverse

Name: hmrR [H]

Synonym: cgR_2029

Alternate gene names: 145296108

Gene position: 2234264-2233824 (Counterclockwise)

Preceding gene: 145296109

Following gene: 145296107

Centisome position: 67.42

GC content: 56.46

Gene sequence:

>441_bases
ATGCTGATCGGTGAGGTGTCCAAGCTCAGTGGGGTGAGTGCGCGCATGTTGCGGCACTACGAAAAGCTGGGTTTGGTCGA
GCCGAAGCAGTCGACGGCGGGGTATCGGGAATACTCAGAAGGCGATGTGCGCAGGATTTTCCATATCGAAGGTTTGCGCA
GCTTGGGTCTTAGTTTGAAGCAGGTTGGAGACGCGCTTGAGGATCCAGACTTTGATCCTCAGGCAGTCATTTCCGAGATG
ATTGCTGAGACTTCTGCGCGGATTTCTATGGAACGGGAGTTGCTTGCCAGGCTGAAAGCGGTGCGTCATGCGCAGGCCTC
GGATTGGGAATCGGCGTTGGATGCGGTGCAGATTTTACGTCGCCTGCGATCGGGGGATCCGGCGCAACGTCAAGCCGTGG
CCTTTGACTCTGTCTCTGGTAAAGAAGCAGTTGCGCGCTAG

Upstream 100 bases:

>100_bases
CGAGCGCGCACGCGGTGGCCACCGCCAAGCTCATTGCGGATCCGGACTCCGATTTCATGGCTGATCTGGAGGAAGCGCGG
CGCGTGGATAATATGGGTGC

Downstream 100 bases:

>100_bases
AAACCTTGGTGGAATCGGCGCTTGGTGAGTTGCATTTGAACGTGGAGGGGGCGCTGTCGTGGGCGGTTGTGCAGCGTGGT
GAGGAAGCTGTTGCATTGGC

Product: hypothetical protein

Products: NA

Alternate protein names: Copper efflux regulator; Copper export regulator [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MLIGEVSKLSGVSARMLRHYEKLGLVEPKQSTAGYREYSEGDVRRIFHIEGLRSLGLSLKQVGDALEDPDFDPQAVISEM
IAETSARISMERELLARLKAVRHAQASDWESALDAVQILRRLRSGDPAQRQAVAFDSVSGKEAVAR

Sequences:

>Translated_146_residues
MLIGEVSKLSGVSARMLRHYEKLGLVEPKQSTAGYREYSEGDVRRIFHIEGLRSLGLSLKQVGDALEDPDFDPQAVISEM
IAETSARISMERELLARLKAVRHAQASDWESALDAVQILRRLRSGDPAQRQAVAFDSVSGKEAVAR
>Mature_146_residues
MLIGEVSKLSGVSARMLRHYEKLGLVEPKQSTAGYREYSEGDVRRIFHIEGLRSLGLSLKQVGDALEDPDFDPQAVISEM
IAETSARISMERELLARLKAVRHAQASDWESALDAVQILRRLRSGDPAQRQAVAFDSVSGKEAVAR

Specific function: Regulates the transcription of actP. It detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations. In the absence of copper, it negatively regulates the transcription of actP [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16164; Mature: 16164

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIGEVSKLSGVSARMLRHYEKLGLVEPKQSTAGYREYSEGDVRRIFHIEGLRSLGLSLK
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHH
QVGDALEDPDFDPQAVISEMIAETSARISMERELLARLKAVRHAQASDWESALDAVQILR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RLRSGDPAQRQAVAFDSVSGKEAVAR
HHHCCCCHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure
MLIGEVSKLSGVSARMLRHYEKLGLVEPKQSTAGYREYSEGDVRRIFHIEGLRSLGLSLK
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHH
QVGDALEDPDFDPQAVISEMIAETSARISMERELLARLKAVRHAQASDWESALDAVQILR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RLRSGDPAQRQAVAFDSVSGKEAVAR
HHHCCCCHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11936079 [H]