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The map label for this gene is galE [H]

Identifier: 145295826

GI number: 145295826

Start: 1942063

End: 1943052

Strand: Direct

Name: galE [H]

Synonym: cgR_1751

Alternate gene names: 145295826

Gene position: 1942063-1943052 (Clockwise)

Preceding gene: 145295825

Following gene: 145295828

Centisome position: 58.6

GC content: 53.94

Gene sequence:

>990_bases
ATGAAGCTTCTGGTTACCGGTGGCGCTGGCTATGTTGGCAGCGTTGCTGCCGCTGTTCTTCTAGAACATGGGCACGATGT
CACAATCATTGACAATTTCAGTACCGGCAACCGTGAAGCAGTCCCTGCTGACGCTCGCCTGATAGAAGGTGACGTCAGCG
ATATCGTTGAGGAAGTCCTTTCTGAAGGCGGATTCGAGGGTGTCGTCCACTTCGCTGCTCGCTCATTGGTAGGCGAATCA
GTGGAAAAGCCCAATGAATACTGGCACGACAATGTGGTCACGGCGCTCACCTTGCTCGATGCAATGCGTGCCCATGGGGT
GAACAACCTTGTGTTCTCCTCCACTGCTGCTACCTACGGTGAACCAGACGTTGTTCCCATCACCGAGGACATGCCCACCC
AGCCCACCAATGCTTATGGCGCAACGAAGCTGTCCATCGACTACGCAATTACGTCCTACGCTGCTGCTTTTGGTCTGGCT
GCAACCAGCTTGCGCTACTTCAACGTTGCTGGCGCATACGGAAACATCGGTGAAAATCGTGAAGTTGAAACTCACCTCAT
TCCACTAGTGCTGCAGGTAGCAACCGGTCACCGCGAGAAAATCTTCATGTTCGGCGATGACTGGCCTACTCCCGATGGAA
CCGCGGTCCGCGATTACATCCACATTCTTGATCTTGCCAAAGCACACGTGTTGGCTTTGGAATCCAACGAAGCCGGTAAG
CACCGCATTTTCAACCTTGGTTCCGGAGATGGCTACAGCGTGAAACAGGTTGTGGAGATGTGCCGTGAAGTAACCGGACA
TCCCATCCCGGCAGAGGTCGCACCCAGGCGTGCAGGAGATCCAGCAACACTAATTGCATCTTCTGAGAAGGCAAAGCAAG
AACTGGGTTGGACCCCTGAGCACACTGATCTGCGCACCATCGTTGAGGACGCTTGGGCGTTTACATCCGCACTGGGCGAT
CGTTCCCATGCTGCAAAGAAGAAAGCTTAA

Upstream 100 bases:

>100_bases
GCAGGGCCGGGTCGTGATCACCCACAACGGCTCCAGCGTAGAACTGATTGACGATCTTGCACATGCAGTCCGCGTAGAAA
AGGTTGAGGGCTAACACACG

Downstream 100 bases:

>100_bases
GCTTTCGGATCGGGGACGTGAAAGTCCCGCAATTGCTGGTTGCCGCGGAGGCAGGCGTCGATAAGCTTTGTTGTTTCGCC
GTTGAACAACCCTTCGCGCA

Product: hypothetical protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKLLVTGGAGYVGSVAAAVLLEHGHDVTIIDNFSTGNREAVPADARLIEGDVSDIVEEVLSEGGFEGVVHFAARSLVGES
VEKPNEYWHDNVVTALTLLDAMRAHGVNNLVFSSTAATYGEPDVVPITEDMPTQPTNAYGATKLSIDYAITSYAAAFGLA
ATSLRYFNVAGAYGNIGENREVETHLIPLVLQVATGHREKIFMFGDDWPTPDGTAVRDYIHILDLAKAHVLALESNEAGK
HRIFNLGSGDGYSVKQVVEMCREVTGHPIPAEVAPRRAGDPATLIASSEKAKQELGWTPEHTDLRTIVEDAWAFTSALGD
RSHAAKKKA

Sequences:

>Translated_329_residues
MKLLVTGGAGYVGSVAAAVLLEHGHDVTIIDNFSTGNREAVPADARLIEGDVSDIVEEVLSEGGFEGVVHFAARSLVGES
VEKPNEYWHDNVVTALTLLDAMRAHGVNNLVFSSTAATYGEPDVVPITEDMPTQPTNAYGATKLSIDYAITSYAAAFGLA
ATSLRYFNVAGAYGNIGENREVETHLIPLVLQVATGHREKIFMFGDDWPTPDGTAVRDYIHILDLAKAHVLALESNEAGK
HRIFNLGSGDGYSVKQVVEMCREVTGHPIPAEVAPRRAGDPATLIASSEKAKQELGWTPEHTDLRTIVEDAWAFTSALGD
RSHAAKKKA
>Mature_329_residues
MKLLVTGGAGYVGSVAAAVLLEHGHDVTIIDNFSTGNREAVPADARLIEGDVSDIVEEVLSEGGFEGVVHFAARSLVGES
VEKPNEYWHDNVVTALTLLDAMRAHGVNNLVFSSTAATYGEPDVVPITEDMPTQPTNAYGATKLSIDYAITSYAAAFGLA
ATSLRYFNVAGAYGNIGENREVETHLIPLVLQVATGHREKIFMFGDDWPTPDGTAVRDYIHILDLAKAHVLALESNEAGK
HRIFNLGSGDGYSVKQVVEMCREVTGHPIPAEVAPRRAGDPATLIASSEKAKQELGWTPEHTDLRTIVEDAWAFTSALGD
RSHAAKKKA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=334, Percent_Identity=42.814371257485, Blast_Score=235, Evalue=4e-62,
Organism=Homo sapiens, GI56118217, Length=334, Percent_Identity=42.814371257485, Blast_Score=235, Evalue=4e-62,
Organism=Homo sapiens, GI189083684, Length=334, Percent_Identity=42.814371257485, Blast_Score=235, Evalue=4e-62,
Organism=Homo sapiens, GI42516563, Length=308, Percent_Identity=26.2987012987013, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI7657641, Length=276, Percent_Identity=25, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI4504031, Length=335, Percent_Identity=26.865671641791, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786974, Length=332, Percent_Identity=41.566265060241, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1788353, Length=340, Percent_Identity=26.4705882352941, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI48994969, Length=334, Percent_Identity=26.0479041916168, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788366, Length=358, Percent_Identity=27.6536312849162, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790049, Length=263, Percent_Identity=26.615969581749, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71982035, Length=340, Percent_Identity=39.1176470588235, Blast_Score=212, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI71982038, Length=342, Percent_Identity=38.8888888888889, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17568069, Length=328, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115532424, Length=327, Percent_Identity=22.3241590214067, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=39.4736842105263, Blast_Score=223, Evalue=3e-59,
Organism=Drosophila melanogaster, GI19923002, Length=338, Percent_Identity=38.1656804733728, Blast_Score=200, Evalue=9e-52,
Organism=Drosophila melanogaster, GI21356223, Length=309, Percent_Identity=23.9482200647249, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35263; Mature: 35263

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLVTGGAGYVGSVAAAVLLEHGHDVTIIDNFSTGNREAVPADARLIEGDVSDIVEEVL
CEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHEECCCHHHHHHHHH
SEGGFEGVVHFAARSLVGESVEKPNEYWHDNVVTALTLLDAMRAHGVNNLVFSSTAATYG
HCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
EPDVVPITEDMPTQPTNAYGATKLSIDYAITSYAAAFGLAATSLRYFNVAGAYGNIGENR
CCCEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCC
EVETHLIPLVLQVATGHREKIFMFGDDWPTPDGTAVRDYIHILDLAKAHVLALESNEAGK
CHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCC
HRIFNLGSGDGYSVKQVVEMCREVTGHPIPAEVAPRRAGDPATLIASSEKAKQELGWTPE
EEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCCCC
HTDLRTIVEDAWAFTSALGDRSHAAKKKA
CHHHHHHHHHHHHHHHHHCCHHHHHCCCC
>Mature Secondary Structure
MKLLVTGGAGYVGSVAAAVLLEHGHDVTIIDNFSTGNREAVPADARLIEGDVSDIVEEVL
CEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHEECCCHHHHHHHHH
SEGGFEGVVHFAARSLVGESVEKPNEYWHDNVVTALTLLDAMRAHGVNNLVFSSTAATYG
HCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
EPDVVPITEDMPTQPTNAYGATKLSIDYAITSYAAAFGLAATSLRYFNVAGAYGNIGENR
CCCEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCC
EVETHLIPLVLQVATGHREKIFMFGDDWPTPDGTAVRDYIHILDLAKAHVLALESNEAGK
CHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCC
HRIFNLGSGDGYSVKQVVEMCREVTGHPIPAEVAPRRAGDPATLIASSEKAKQELGWTPE
EEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCCCC
HTDLRTIVEDAWAFTSALGDRSHAAKKKA
CHHHHHHHHHHHHHHHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8921853; 12948626 [H]