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The map label for this gene is aroE [H]

Identifier: 145295751

GI number: 145295751

Start: 1863059

End: 1863889

Strand: Reverse

Name: aroE [H]

Synonym: cgR_1677

Alternate gene names: 145295751

Gene position: 1863889-1863059 (Counterclockwise)

Preceding gene: 145295752

Following gene: 145295747

Centisome position: 56.24

GC content: 60.77

Gene sequence:

>831_bases
TTGGGTTCTCACATCACTCACCGGGCGGCCGTACTCGGCTCACCCATCGAGCATTCCAAATCCCCAGTCCTCCACAACAC
CGGCTATAAAGCCCTCGGACTGGACCAATGGGAATACGACCGCTTTGAGTGCACCGGCGACATGCTCCCCGGAATCGTCT
CCGGCGCTGATGAAACCTACCGCGGATTCTCCGTCACTATGCCGTCCAAATTCGCAGCCCTCGAATTCGCCGACGAAGTA
ACCGAACGCGCCCGCGCCATCGGCTCCGCAAACACACTTCTGCGCACCGAAACCGGATGGCGCGCAGACAACACCGACGT
CGACGGCATCAGGGGAGCCCTCGGTGAACTCCTCGGCAGCGCATCACTGGCCGGCAAACACGCCATCGTCATCGGCTCCG
GCGGCACCGCACGCCCCGCCATCTGGGCACTCATCGAAGCCGGGGTCGCGCGGATCACGGTGCTCAACCGCTCCGATCGA
ACCGCCGAACTGCAAACGCTTTTCGACGAAACCCCCACCACCTTGGCCTACGCCCCGCTCGAACATCTCGACATCGAAGC
CGACGTCGTAGTCTCTACAGTGCCCTCCGCAGCAATCGCAGGCCTCGAAGACACACTCGCAATCGCCCCAGTCCTCGACG
TCATCTACGATCCTTGGCCAACACCACTCGTAGAAGTCGCACGAGCCAAAGGTCTCAAAGCTGTCGGAGGCCACGTCATG
CTGGCACACCAGTCCTACGGACAGTTTGAACAATTCACCGGAATGGATGCACCCCGCGATGCTATGCGTGAGGCTTTGGA
AGAATCCCTAGGCATCTCGGAAGAACACTAG

Upstream 100 bases:

>100_bases
ACCGTGTTCAACGACACCTTCGAAGAGCACGAAGCCGACATTGAGCAAGCTTTGAACAGTGGCGTTCTAGACAGCAACCG
ATAAGGATCAACGAATAAAA

Downstream 100 bases:

>100_bases
GTCCCTCTGGTGGCGGCCAAGGGGCGACTTCGCATCACCCGACTTCTCACGCTCAACTTCGCTAGGAAATCCGGGGGATT
CCGAGGGAAGTCGTGTGATG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MGSHITHRAAVLGSPIEHSKSPVLHNTGYKALGLDQWEYDRFECTGDMLPGIVSGADETYRGFSVTMPSKFAALEFADEV
TERARAIGSANTLLRTETGWRADNTDVDGIRGALGELLGSASLAGKHAIVIGSGGTARPAIWALIEAGVARITVLNRSDR
TAELQTLFDETPTTLAYAPLEHLDIEADVVVSTVPSAAIAGLEDTLAIAPVLDVIYDPWPTPLVEVARAKGLKAVGGHVM
LAHQSYGQFEQFTGMDAPRDAMREALEESLGISEEH

Sequences:

>Translated_276_residues
MGSHITHRAAVLGSPIEHSKSPVLHNTGYKALGLDQWEYDRFECTGDMLPGIVSGADETYRGFSVTMPSKFAALEFADEV
TERARAIGSANTLLRTETGWRADNTDVDGIRGALGELLGSASLAGKHAIVIGSGGTARPAIWALIEAGVARITVLNRSDR
TAELQTLFDETPTTLAYAPLEHLDIEADVVVSTVPSAAIAGLEDTLAIAPVLDVIYDPWPTPLVEVARAKGLKAVGGHVM
LAHQSYGQFEQFTGMDAPRDAMREALEESLGISEEH
>Mature_275_residues
GSHITHRAAVLGSPIEHSKSPVLHNTGYKALGLDQWEYDRFECTGDMLPGIVSGADETYRGFSVTMPSKFAALEFADEVT
ERARAIGSANTLLRTETGWRADNTDVDGIRGALGELLGSASLAGKHAIVIGSGGTARPAIWALIEAGVARITVLNRSDRT
AELQTLFDETPTTLAYAPLEHLDIEADVVVSTVPSAAIAGLEDTLAIAPVLDVIYDPWPTPLVEVARAKGLKAVGGHVML
AHQSYGQFEQFTGMDAPRDAMREALEESLGISEEH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=289, Percent_Identity=29.0657439446367, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789675, Length=272, Percent_Identity=30.8823529411765, Blast_Score=84, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6320332, Length=279, Percent_Identity=33.6917562724014, Blast_Score=135, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29447; Mature: 29316

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSHITHRAAVLGSPIEHSKSPVLHNTGYKALGLDQWEYDRFECTGDMLPGIVSGADETY
CCCCHHHHHHHHCCCHHHCCCCCEECCCCCEECCCCCCCCHHEECCHHCCHHHCCCCCCC
RGFSVTMPSKFAALEFADEVTERARAIGSANTLLRTETGWRADNTDVDGIRGALGELLGS
CCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHC
ASLAGKHAIVIGSGGTARPAIWALIEAGVARITVLNRSDRTAELQTLFDETPTTLAYAPL
CCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCH
EHLDIEADVVVSTVPSAAIAGLEDTLAIAPVLDVIYDPWPTPLVEVARAKGLKAVGGHVM
HHCCCCHHHEEECCCHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEECCCEEE
LAHQSYGQFEQFTGMDAPRDAMREALEESLGISEEH
EEECCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GSHITHRAAVLGSPIEHSKSPVLHNTGYKALGLDQWEYDRFECTGDMLPGIVSGADETY
CCCHHHHHHHHCCCHHHCCCCCEECCCCCEECCCCCCCCHHEECCHHCCHHHCCCCCCC
RGFSVTMPSKFAALEFADEVTERARAIGSANTLLRTETGWRADNTDVDGIRGALGELLGS
CCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHC
ASLAGKHAIVIGSGGTARPAIWALIEAGVARITVLNRSDRTAELQTLFDETPTTLAYAPL
CCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCH
EHLDIEADVVVSTVPSAAIAGLEDTLAIAPVLDVIYDPWPTPLVEVARAKGLKAVGGHVM
HHCCCCHHHEEECCCHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEECCCEEE
LAHQSYGQFEQFTGMDAPRDAMREALEESLGISEEH
EEECCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA