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The map label for this gene is pyrF

Identifier: 145295730

GI number: 145295730

Start: 1841675

End: 1842511

Strand: Reverse

Name: pyrF

Synonym: cgR_1657

Alternate gene names: 145295730

Gene position: 1842511-1841675 (Counterclockwise)

Preceding gene: 145295731

Following gene: 145295729

Centisome position: 55.59

GC content: 58.78

Gene sequence:

>837_bases
ATGACATTCGGCGAGAAGCTTCTGAACGCCGCCTCCACCCGTGGCAGGCTATGCGTGGGCATTGATCCCCACGAAAGCCT
GCTGACGTCCTGGGGGCTGCCGGTAAACGTAGACGGACTTGCGGAGTTCTCCCGCGCCTGCGTGGAGGCTTTCGCCGACA
CCGTGGCATTGGTGAAGCCTCAGGTGGCGTTCTATGAGCGTTTCGGTTCCGCTGGCTTTGCCATCTTGGAAGAAACCATT
CAGACGCTGCGTGAGCGTGGCTGTTTGGTGGTCTCTGACGCCAAACGCGGCGATATTGGCTCCACCATGGCTGGCTATGC
CTCAGCGTGGTTAGATCCAGCGTCACCGCTGTCTAGCGACGCTGTGACGGTCTCTCCCTACCTTGGTTTTCATTCCTTGG
ACCCAGTGTTCGAACTTGCCGAGCAACACGGCAGGGGAGTGTTTGTCTTGGCCGCGACCTCAAACCCTGAGGCCCGCGAA
CTCCAGGACCAGCAAAACGCTGACGGCGTGAGCATTTCCCAGCAGATCGTGGATCAGGCAGCGGCGCTTAACGCGCCTTA
TATGGCCCAGGGCAAGGCTGGCAACATTGGCGTCGTCATCGGCGCCACCTTGTCCAAACCACCACGCTTATCGACGCTCG
GGGGCGCCATTTTGATGCCCGGCGTCGGCGCCCAGGGCGGCACGGCAAGCGACGTTGATGAGATTGCGGGAGACATGGCT
CATCTTGCGTTCCCAAATGTCTCTAGAAGTATTTTGGCGACAGGCCCAGATATCGCTGAAATGAAGAATTCTGTGGCAAA
AACTGCTGCAGACTTTCCTGGTTTCCCCAGGTCATAG

Upstream 100 bases:

>100_bases
GTGTCACCGCAGCTGTTCAGGGCATTGAGGCCCTGCGTGAGGGCGTTGTCAGCGTCCGCGCGCTGCAGGAACTCGACCAC
GCAGTCAAGGCTTAAGCCCT

Downstream 100 bases:

>100_bases
TCGCGGAAACGGCCCTTAATTGCAAGCCTGTGACCTGCAGGTTTAGCTTTTAGGGGTCCTGCCACCTTTGTGTTTGCGAA
AGTAGTGCTAGACTATTCGA

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MTFGEKLLNAASTRGRLCVGIDPHESLLTSWGLPVNVDGLAEFSRACVEAFADTVALVKPQVAFYERFGSAGFAILEETI
QTLRERGCLVVSDAKRGDIGSTMAGYASAWLDPASPLSSDAVTVSPYLGFHSLDPVFELAEQHGRGVFVLAATSNPEARE
LQDQQNADGVSISQQIVDQAAALNAPYMAQGKAGNIGVVIGATLSKPPRLSTLGGAILMPGVGAQGGTASDVDEIAGDMA
HLAFPNVSRSILATGPDIAEMKNSVAKTAADFPGFPRS

Sequences:

>Translated_278_residues
MTFGEKLLNAASTRGRLCVGIDPHESLLTSWGLPVNVDGLAEFSRACVEAFADTVALVKPQVAFYERFGSAGFAILEETI
QTLRERGCLVVSDAKRGDIGSTMAGYASAWLDPASPLSSDAVTVSPYLGFHSLDPVFELAEQHGRGVFVLAATSNPEARE
LQDQQNADGVSISQQIVDQAAALNAPYMAQGKAGNIGVVIGATLSKPPRLSTLGGAILMPGVGAQGGTASDVDEIAGDMA
HLAFPNVSRSILATGPDIAEMKNSVAKTAADFPGFPRS
>Mature_277_residues
TFGEKLLNAASTRGRLCVGIDPHESLLTSWGLPVNVDGLAEFSRACVEAFADTVALVKPQVAFYERFGSAGFAILEETIQ
TLRERGCLVVSDAKRGDIGSTMAGYASAWLDPASPLSSDAVTVSPYLGFHSLDPVFELAEQHGRGVFVLAATSNPEAREL
QDQQNADGVSISQQIVDQAAALNAPYMAQGKAGNIGVVIGATLSKPPRLSTLGGAILMPGVGAQGGTASDVDEIAGDMAH
LAFPNVSRSILATGPDIAEMKNSVAKTAADFPGFPRS

Specific function: Unknown

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 2 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRF_CORGB (A4QEI3)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138551.1
- ProteinModelPortal:   A4QEI3
- SMR:   A4QEI3
- STRING:   A4QEI3
- GeneID:   4992968
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1657
- eggNOG:   COG0284
- HOGENOM:   HBG348634
- OMA:   LLCRTSN
- ProtClustDB:   PRK00125
- HAMAP:   MF_01215
- InterPro:   IPR013785
- InterPro:   IPR018089
- InterPro:   IPR011995
- InterPro:   IPR001754
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00934
- TIGRFAMs:   TIGR02127

Pfam domain/function: PF00215 OMPdecase; SSF51366 RibP_bind_barrel

EC number: =4.1.1.23

Molecular weight: Translated: 28907; Mature: 28776

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00156 OMPDECASE

Important sites: ACT_SITE 95-95

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFGEKLLNAASTRGRLCVGIDPHESLLTSWGLPVNVDGLAEFSRACVEAFADTVALVKP
CCHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCH
QVAFYERFGSAGFAILEETIQTLRERGCLVVSDAKRGDIGSTMAGYASAWLDPASPLSSD
HHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCC
AVTVSPYLGFHSLDPVFELAEQHGRGVFVLAATSNPEARELQDQQNADGVSISQQIVDQA
CEEEECCCCCCCCCHHHHHHHHHCCEEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHH
AALNAPYMAQGKAGNIGVVIGATLSKPPRLSTLGGAILMPGVGAQGGTASDVDEIAGDMA
HHCCCCCEECCCCCCEEEEEECCCCCCCCCHHHCCEEEECCCCCCCCCCCCHHHHHHHHH
HLAFPNVSRSILATGPDIAEMKNSVAKTAADFPGFPRS
HHHCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TFGEKLLNAASTRGRLCVGIDPHESLLTSWGLPVNVDGLAEFSRACVEAFADTVALVKP
CHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCH
QVAFYERFGSAGFAILEETIQTLRERGCLVVSDAKRGDIGSTMAGYASAWLDPASPLSSD
HHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCC
AVTVSPYLGFHSLDPVFELAEQHGRGVFVLAATSNPEARELQDQQNADGVSISQQIVDQA
CEEEECCCCCCCCCHHHHHHHHHCCEEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHH
AALNAPYMAQGKAGNIGVVIGATLSKPPRLSTLGGAILMPGVGAQGGTASDVDEIAGDMA
HHCCCCCEECCCCCCEEEEEECCCCCCCCCHHHCCEEEECCCCCCCCCCCCHHHHHHHHH
HLAFPNVSRSILATGPDIAEMKNSVAKTAADFPGFPRS
HHHCCCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA