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The map label for this gene is tkt [H]

Identifier: 145295697

GI number: 145295697

Start: 1804320

End: 1806413

Strand: Direct

Name: tkt [H]

Synonym: cgR_1624

Alternate gene names: 145295697

Gene position: 1804320-1806413 (Clockwise)

Preceding gene: 145295695

Following gene: 145295698

Centisome position: 54.44

GC content: 58.55

Gene sequence:

>2094_bases
TTGACGCTGTCACCTGAACTTCAGGCGCTCACTGTACGCAATTACCCCTCTGATTGGTCCGATGTGGACACCAAGGCTGT
AGACACTGTTCGTGTCCTCGCTGCAGACGCTGTAGAAAACTGTGGCTCCGGCCACCCAGGCACCGCAATGAGCCTGGCTC
CCCTTGCATACACCTTGTACCAGCGGGTTATGAACGTAGATCCACAGGACACCAACTGGGCAGGCCGTGACCGCTTCGTT
CTTTCTTGTGGCCACTCCTCTTTGACCCAGTACATCCAGCTTTACTTGGGTGGATTCGGCCTTGAGATGGATGACCTGAA
GGCTCTGCGCACCTGGGATTCCTTGACCCCAGGACACCCTGAGTACCGCCACACCAAGGGCGTTGAGATCACCACTGGCC
CTCTTGGCCAGGGTCTTGCATCTGCAGTTGGTATGGCCATGGCTGCTCGTCGTGAGCGTGGCCTATTCGACCCAACCGCT
GCTGAGGGCGAATCCCCATTCGACCACCACATCTACGTCATTGCTTCTGATGGTGACCTGCAGGAAGGTGTCACCTCTGA
GGCATCCTCCATCGCTGGCACCCAGCAGCTGGGCAACATCATCGTGTTCTGGGATGACAACCGCATCTCCATCGAAGACA
ACACTGAGATCGCTTTCAACGAGGACGTTGTTGCTCGTTACAAGGCTTACGGCTGGCAGACCATTGAGGTTGAGGCTGGC
GAGGACGTTGCAGCAATCGAAGCTGCAGTGGCTGAGGCTAAGAAGGACACCAAGCGACCTACCTTCATCCGCGTTCGCAC
CATCATCGGCTTCCCAGCTCCAACCATGATGAACACCGGTGCTGTGCACGGTGCTGCTCTTGGCGCAGCTGAGGTTGCAG
CAACCAAGACTGAGCTTGGATTCGATCCTGAGGCTCACTTCGCGATCGACGACGAGGTCATCGCTCACACCCGCTCCCTC
GCAGAGCGCGCTGCAGAGAAGAAGGCTGCATGGCAGGTCAAGTTCGATGAGTGGGCAGCTGCCAACCCTGAGAACAAGGC
TCTGTTCGATCGCCTGAACTCCCGTGAGCTTCCAGCGGGCTACGCTGACGAGCTCCCAACATGGGATGCAGATGAGAAGG
GCGTCGCAACTCGTAAGGCGTCCGAGGCTGCACTTCAGGCACTGGGCAAGACCCTTCCTGAGCTGTGGGGCGGTTCCGCT
GACCTCGCAGGTTCCAACAACACCGTGATCAAGGGCTCCCCTTCCTTCGGCCCTGAGTCCATCTCCACCGAGACCTGGTC
TGCTGAGCCTTACGGCCGTAACCTGCACTTCGGTATCCGTGAGCACGCTATGGGATCCATCCTCAACGGCATTTCCCTCC
ACGGTGGCACCCGCCCATACGGCGGAACCTTCCTCATCTTCTCCGACTACATGCGTCCTGCAGTTCGTCTTGCAGCTCTC
ATGGAGACCGACGCTTACTACGTCTGGACCCACGACTCCATCGGTCTGGGCGAAGATGGCCCAACCCACCAGCCTGTTGA
AACCTTGGCTGCACTGCGCGCCATCCCAGGTCTGTCCGTCCTGCGTCCTGCAGATGCGAATGAGACCGCCCAGGCTTGGG
CTGCAGCACTTGAGTACAATGAAGGCCCTAAGGGTCTTGCACTGACCCGCCAGAACGTTCCTGTTCTGGAAGGCACCAAG
GAGAAGGCTGCTGAAGGCGTTCGCCGCGGTGGCTACGTCCTGGTTGAGGGTTCCAAGGAAACCCCAGATGTGATCCTCAT
GGGCTCCGGCTCCGAGGTTCAGCTTGCAGTTAACGCTGCGAAGGCTCTGGAAGCTGAGGGCGTTGCAGCTCGCGTTGTTT
CCGTTCCTTGCATGGATTGGTTCCAGGAGCAGGACGCAGAGTACATCGAGTCCGTTCTGCCTGCAGCTGTGACCGCTCGT
GTGTCTGTTGAAGCTGGCATCGCAATGCCTTGGTACCGCTTCTTGGGCACCCAGGGCCGTGCTGTCTCCCTTGAGCACTT
CGGTGCTTCTGCGGATTACCAGACCCTGTTTGAGAAGTTCGGCATCACCACCGATGCAGTCGTGGCAGCGGCCAAGGACT
CCATTAACGGTTAA

Upstream 100 bases:

>100_bases
AATTTGAACCAATTAACCTAAGTCGTAGATCTGATCATCGGATCTAACGAAAACGAACCAAAACTTTGGTCCCGGTTTAA
CCCAGGAAGGATTGACCACC

Downstream 100 bases:

>100_bases
TTGCCCTGCTGTTTTTAGCTTCAACCCGGGGCAATATGATCCTCCGGAATTTTATTGCCCCGGGTTGTTGTTAATCGGTA
TAAAGGGTCTTAAGCACATC

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 697; Mature: 696

Protein sequence:

>697_residues
MTLSPELQALTVRNYPSDWSDVDTKAVDTVRVLAADAVENCGSGHPGTAMSLAPLAYTLYQRVMNVDPQDTNWAGRDRFV
LSCGHSSLTQYIQLYLGGFGLEMDDLKALRTWDSLTPGHPEYRHTKGVEITTGPLGQGLASAVGMAMAARRERGLFDPTA
AEGESPFDHHIYVIASDGDLQEGVTSEASSIAGTQQLGNIIVFWDDNRISIEDNTEIAFNEDVVARYKAYGWQTIEVEAG
EDVAAIEAAVAEAKKDTKRPTFIRVRTIIGFPAPTMMNTGAVHGAALGAAEVAATKTELGFDPEAHFAIDDEVIAHTRSL
AERAAEKKAAWQVKFDEWAAANPENKALFDRLNSRELPAGYADELPTWDADEKGVATRKASEAALQALGKTLPELWGGSA
DLAGSNNTVIKGSPSFGPESISTETWSAEPYGRNLHFGIREHAMGSILNGISLHGGTRPYGGTFLIFSDYMRPAVRLAAL
METDAYYVWTHDSIGLGEDGPTHQPVETLAALRAIPGLSVLRPADANETAQAWAAALEYNEGPKGLALTRQNVPVLEGTK
EKAAEGVRRGGYVLVEGSKETPDVILMGSGSEVQLAVNAAKALEAEGVAARVVSVPCMDWFQEQDAEYIESVLPAAVTAR
VSVEAGIAMPWYRFLGTQGRAVSLEHFGASADYQTLFEKFGITTDAVVAAAKDSING

Sequences:

>Translated_697_residues
MTLSPELQALTVRNYPSDWSDVDTKAVDTVRVLAADAVENCGSGHPGTAMSLAPLAYTLYQRVMNVDPQDTNWAGRDRFV
LSCGHSSLTQYIQLYLGGFGLEMDDLKALRTWDSLTPGHPEYRHTKGVEITTGPLGQGLASAVGMAMAARRERGLFDPTA
AEGESPFDHHIYVIASDGDLQEGVTSEASSIAGTQQLGNIIVFWDDNRISIEDNTEIAFNEDVVARYKAYGWQTIEVEAG
EDVAAIEAAVAEAKKDTKRPTFIRVRTIIGFPAPTMMNTGAVHGAALGAAEVAATKTELGFDPEAHFAIDDEVIAHTRSL
AERAAEKKAAWQVKFDEWAAANPENKALFDRLNSRELPAGYADELPTWDADEKGVATRKASEAALQALGKTLPELWGGSA
DLAGSNNTVIKGSPSFGPESISTETWSAEPYGRNLHFGIREHAMGSILNGISLHGGTRPYGGTFLIFSDYMRPAVRLAAL
METDAYYVWTHDSIGLGEDGPTHQPVETLAALRAIPGLSVLRPADANETAQAWAAALEYNEGPKGLALTRQNVPVLEGTK
EKAAEGVRRGGYVLVEGSKETPDVILMGSGSEVQLAVNAAKALEAEGVAARVVSVPCMDWFQEQDAEYIESVLPAAVTAR
VSVEAGIAMPWYRFLGTQGRAVSLEHFGASADYQTLFEKFGITTDAVVAAAKDSING
>Mature_696_residues
TLSPELQALTVRNYPSDWSDVDTKAVDTVRVLAADAVENCGSGHPGTAMSLAPLAYTLYQRVMNVDPQDTNWAGRDRFVL
SCGHSSLTQYIQLYLGGFGLEMDDLKALRTWDSLTPGHPEYRHTKGVEITTGPLGQGLASAVGMAMAARRERGLFDPTAA
EGESPFDHHIYVIASDGDLQEGVTSEASSIAGTQQLGNIIVFWDDNRISIEDNTEIAFNEDVVARYKAYGWQTIEVEAGE
DVAAIEAAVAEAKKDTKRPTFIRVRTIIGFPAPTMMNTGAVHGAALGAAEVAATKTELGFDPEAHFAIDDEVIAHTRSLA
ERAAEKKAAWQVKFDEWAAANPENKALFDRLNSRELPAGYADELPTWDADEKGVATRKASEAALQALGKTLPELWGGSAD
LAGSNNTVIKGSPSFGPESISTETWSAEPYGRNLHFGIREHAMGSILNGISLHGGTRPYGGTFLIFSDYMRPAVRLAALM
ETDAYYVWTHDSIGLGEDGPTHQPVETLAALRAIPGLSVLRPADANETAQAWAAALEYNEGPKGLALTRQNVPVLEGTKE
KAAEGVRRGGYVLVEGSKETPDVILMGSGSEVQLAVNAAKALEAEGVAARVVSVPCMDWFQEQDAEYIESVLPAAVTARV
SVEAGIAMPWYRFLGTQGRAVSLEHFGASADYQTLFEKFGITTDAVVAAAKDSING

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=589, Percent_Identity=26.8251273344652, Blast_Score=156, Evalue=7e-38,
Organism=Homo sapiens, GI4507521, Length=589, Percent_Identity=26.8251273344652, Blast_Score=156, Evalue=7e-38,
Organism=Homo sapiens, GI133778974, Length=683, Percent_Identity=24.0117130307467, Blast_Score=114, Evalue=3e-25,
Organism=Escherichia coli, GI48994911, Length=670, Percent_Identity=46.4179104477612, Blast_Score=563, Evalue=1e-162,
Organism=Escherichia coli, GI1788808, Length=671, Percent_Identity=44.2622950819672, Blast_Score=518, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17539652, Length=706, Percent_Identity=25.3541076487252, Blast_Score=147, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6325331, Length=682, Percent_Identity=44.1348973607038, Blast_Score=533, Evalue=1e-152,
Organism=Saccharomyces cerevisiae, GI6319593, Length=684, Percent_Identity=43.7134502923977, Blast_Score=522, Evalue=1e-149,
Organism=Drosophila melanogaster, GI45551847, Length=591, Percent_Identity=25.8883248730964, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI45550715, Length=591, Percent_Identity=25.8883248730964, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24645119, Length=544, Percent_Identity=26.4705882352941, Blast_Score=136, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24666278, Length=590, Percent_Identity=25.2542372881356, Blast_Score=134, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 74767; Mature: 74636

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSPELQALTVRNYPSDWSDVDTKAVDTVRVLAADAVENCGSGHPGTAMSLAPLAYTLY
CCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
QRVMNVDPQDTNWAGRDRFVLSCGHSSLTQYIQLYLGGFGLEMDDLKALRTWDSLTPGHP
HHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCC
EYRHTKGVEITTGPLGQGLASAVGMAMAARRERGLFDPTAAEGESPFDHHIYVIASDGDL
CCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCH
QEGVTSEASSIAGTQQLGNIIVFWDDNRISIEDNTEIAFNEDVVARYKAYGWQTIEVEAG
HHCCHHHHHHHHCHHHHCCEEEEECCCEEEECCCCEEEECCHHHHHHHHCCCEEEEEECC
EDVAAIEAAVAEAKKDTKRPTFIRVRTIIGFPAPTMMNTGAVHGAALGAAEVAATKTELG
CCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHCCCCCCCHHHHCHHHHHHHHHHCC
FDPEAHFAIDDEVIAHTRSLAERAAEKKAAWQVKFDEWAAANPENKALFDRLNSRELPAG
CCCCCCEEECHHHHHHHHHHHHHHHHHHHEEEEEEHHHCCCCCCCHHHHHHCCCCCCCCC
YADELPTWDADEKGVATRKASEAALQALGKTLPELWGGSADLAGSNNTVIKGSPSFGPES
CHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCC
ISTETWSAEPYGRNLHFGIREHAMGSILNGISLHGGTRPYGGTFLIFSDYMRPAVRLAAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCEEEEEHHHHHHHHHHHHH
METDAYYVWTHDSIGLGEDGPTHQPVETLAALRAIPGLSVLRPADANETAQAWAAALEYN
HHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHCC
EGPKGLALTRQNVPVLEGTKEKAAEGVRRGGYVLVEGSKETPDVILMGSGSEVQLAVNAA
CCCCCEEEECCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCEEEEEEEHH
KALEAEGVAARVVSVPCMDWFQEQDAEYIESVLPAAVTARVSVEAGIAMPWYRFLGTQGR
HHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHCCCCC
AVSLEHFGASADYQTLFEKFGITTDAVVAAAKDSING
EEEHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TLSPELQALTVRNYPSDWSDVDTKAVDTVRVLAADAVENCGSGHPGTAMSLAPLAYTLY
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
QRVMNVDPQDTNWAGRDRFVLSCGHSSLTQYIQLYLGGFGLEMDDLKALRTWDSLTPGHP
HHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCC
EYRHTKGVEITTGPLGQGLASAVGMAMAARRERGLFDPTAAEGESPFDHHIYVIASDGDL
CCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCH
QEGVTSEASSIAGTQQLGNIIVFWDDNRISIEDNTEIAFNEDVVARYKAYGWQTIEVEAG
HHCCHHHHHHHHCHHHHCCEEEEECCCEEEECCCCEEEECCHHHHHHHHCCCEEEEEECC
EDVAAIEAAVAEAKKDTKRPTFIRVRTIIGFPAPTMMNTGAVHGAALGAAEVAATKTELG
CCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHCCCCCCCHHHHCHHHHHHHHHHCC
FDPEAHFAIDDEVIAHTRSLAERAAEKKAAWQVKFDEWAAANPENKALFDRLNSRELPAG
CCCCCCEEECHHHHHHHHHHHHHHHHHHHEEEEEEHHHCCCCCCCHHHHHHCCCCCCCCC
YADELPTWDADEKGVATRKASEAALQALGKTLPELWGGSADLAGSNNTVIKGSPSFGPES
CHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCC
ISTETWSAEPYGRNLHFGIREHAMGSILNGISLHGGTRPYGGTFLIFSDYMRPAVRLAAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCEEEEEHHHHHHHHHHHHH
METDAYYVWTHDSIGLGEDGPTHQPVETLAALRAIPGLSVLRPADANETAQAWAAALEYN
HHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHCC
EGPKGLALTRQNVPVLEGTKEKAAEGVRRGGYVLVEGSKETPDVILMGSGSEVQLAVNAA
CCCCCEEEECCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCEEEEEEEHH
KALEAEGVAARVVSVPCMDWFQEQDAEYIESVLPAAVTARVSVEAGIAMPWYRFLGTQGR
HHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHCCCCC
AVSLEHFGASADYQTLFEKFGITTDAVVAAAKDSING
EEEHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]