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The map label for this gene is cobL [H]

Identifier: 145295618

GI number: 145295618

Start: 1706975

End: 1708255

Strand: Reverse

Name: cobL [H]

Synonym: cgR_1545

Alternate gene names: 145295618

Gene position: 1708255-1706975 (Counterclockwise)

Preceding gene: 145295619

Following gene: 145295616

Centisome position: 51.54

GC content: 53.71

Gene sequence:

>1281_bases
ATGTCAGCACCCGACTCCGCTTCAGGATCAGAGCGCGGTCATGAGCGCACCCACTTTGCGGTAGTCGGTGACTCCCAGGA
TCTAGCGCAAGCAACAGCACCTAGGGAGCCAGCAGAATCAATTACTTTGATTGGCATTGGTACTGATGGGTTTGAGGGGC
TTGGTCTCAAGGCACGACAAGCGTTGCAACGTGCCTCTGTGGTGATTGGATCTTGGCGCCAGCTCAACCTTGTACCTGAT
GCCATTAAGGCAGAGCGGCGTCCATGGCCGGGTAATACAAAGCATCCAGACTTAGACGCTTTGTTTAAAGAGTTCCTCGG
CCGACATGTGGCTGTATTGGCTTCTGGCGATCCGCTATTTTACGGCGTGGGCACCGCAATGGTCCATGTGCTGGGGATGG
ATAGACTCACGGTTATTCCGGGACCATCATCCGCGTCGCTTGCTTGCGCCCGCTTGGGTTGGACAGTCAACCGCACACGG
GTGGTGTACCTAGGACAAGAACCCATTGAGACACTCATCCCGATTATTGAATCAGGCGCTCAATTCCTCGTCTTGGGTAA
AGATGAATTCAGTACAGCTCAAGTTGCCACGTTGTTGAATGAACTCGGACTGGGGGAGACTCCACTGACTGTGCTCAGCG
ATTTGGGCAGTACTGATGAGGAGATCACCCAAGGCACAGCTTCACATCCACCAGCCGCAGTGTCTGTTCTCAATGTGATT
GCCGTGGGAGCTCGCACCGCAATGCCAAAACCCCACTTTGAAGGCGACGTATCAAACGAAGACCTTCGGGCACTGACCGT
GGCAGCTCTAGAACCCACCCAGGGACAAATGCTGTGGACCTTCGGGGATATTGGAGCAGCACTTGCCTGCGATTGGCTAC
GCGCAGCCGGCAACAAGGCGCACGCTATTAGTTTTGCCTCCATGGTTGAGCAAAGCCAAAGGAATGCTCGCAAACTAGGT
GTATCCACCCTCAGTGTGAAAGAGACCCTGTCACCCAAAACGCTCAAAGATATCCGCTATGTGCAAGGACCAGAATCAGC
AAGCCCACATGCCATCTTCATGAACAAAGGCCTAGGCATCGATCTAGTTCCTGAAACCGCATGGATGATGCTGCGGCCTG
GAGGAAAGCTCATTGCGCAAGCCTCCACGGAAGACAACATCGCAAAGCTTCACACACTCCAAGAACAACACGGCGGAATC
ATCAAACACATCCGCATCGATGACACCGATGTGCACCAATGGCGAGTTACAAAGCCGGTGACTCCAGAAGCGGTGAATTA
G

Upstream 100 bases:

>100_bases
GAGTCAGTGGTTGTCGGGGTTTCACAGTCACTTATTCTATGCAGGATTCACCATGTATATCGTGGGGATTTGTCTACAAT
TAGTGGTTATGAGCCAACCG

Downstream 100 bases:

>100_bases
CATCAAAAACCAACCCCATGGGAGCCAGAACCTTCACCACCTGTTCTGCAACACCCTCATGCAAATCATGAATGATCAAC
GAATTCCATGGGGTAATAGT

Product: hypothetical protein

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MSAPDSASGSERGHERTHFAVVGDSQDLAQATAPREPAESITLIGIGTDGFEGLGLKARQALQRASVVIGSWRQLNLVPD
AIKAERRPWPGNTKHPDLDALFKEFLGRHVAVLASGDPLFYGVGTAMVHVLGMDRLTVIPGPSSASLACARLGWTVNRTR
VVYLGQEPIETLIPIIESGAQFLVLGKDEFSTAQVATLLNELGLGETPLTVLSDLGSTDEEITQGTASHPPAAVSVLNVI
AVGARTAMPKPHFEGDVSNEDLRALTVAALEPTQGQMLWTFGDIGAALACDWLRAAGNKAHAISFASMVEQSQRNARKLG
VSTLSVKETLSPKTLKDIRYVQGPESASPHAIFMNKGLGIDLVPETAWMMLRPGGKLIAQASTEDNIAKLHTLQEQHGGI
IKHIRIDDTDVHQWRVTKPVTPEAVN

Sequences:

>Translated_426_residues
MSAPDSASGSERGHERTHFAVVGDSQDLAQATAPREPAESITLIGIGTDGFEGLGLKARQALQRASVVIGSWRQLNLVPD
AIKAERRPWPGNTKHPDLDALFKEFLGRHVAVLASGDPLFYGVGTAMVHVLGMDRLTVIPGPSSASLACARLGWTVNRTR
VVYLGQEPIETLIPIIESGAQFLVLGKDEFSTAQVATLLNELGLGETPLTVLSDLGSTDEEITQGTASHPPAAVSVLNVI
AVGARTAMPKPHFEGDVSNEDLRALTVAALEPTQGQMLWTFGDIGAALACDWLRAAGNKAHAISFASMVEQSQRNARKLG
VSTLSVKETLSPKTLKDIRYVQGPESASPHAIFMNKGLGIDLVPETAWMMLRPGGKLIAQASTEDNIAKLHTLQEQHGGI
IKHIRIDDTDVHQWRVTKPVTPEAVN
>Mature_425_residues
SAPDSASGSERGHERTHFAVVGDSQDLAQATAPREPAESITLIGIGTDGFEGLGLKARQALQRASVVIGSWRQLNLVPDA
IKAERRPWPGNTKHPDLDALFKEFLGRHVAVLASGDPLFYGVGTAMVHVLGMDRLTVIPGPSSASLACARLGWTVNRTRV
VYLGQEPIETLIPIIESGAQFLVLGKDEFSTAQVATLLNELGLGETPLTVLSDLGSTDEEITQGTASHPPAAVSVLNVIA
VGARTAMPKPHFEGDVSNEDLRALTVAALEPTQGQMLWTFGDIGAALACDWLRAAGNKAHAISFASMVEQSQRNARKLGV
STLSVKETLSPKTLKDIRYVQGPESASPHAIFMNKGLGIDLVPETAWMMLRPGGKLIAQASTEDNIAKLHTLQEQHGGII
KHIRIDDTDVHQWRVTKPVTPEAVN

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2241

COG function: function code H; Precorrin-6B methylase 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 45570; Mature: 45439

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPDSASGSERGHERTHFAVVGDSQDLAQATAPREPAESITLIGIGTDGFEGLGLKARQ
CCCCCCCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHH
ALQRASVVIGSWRQLNLVPDAIKAERRPWPGNTKHPDLDALFKEFLGRHVAVLASGDPLF
HHHHHHHHHCCCEEECCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCEE
YGVGTAMVHVLGMDRLTVIPGPSSASLACARLGWTVNRTRVVYLGQEPIETLIPIIESGA
EEHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCEECCEEEEEECCCCHHHHHHHHHCCC
QFLVLGKDEFSTAQVATLLNELGLGETPLTVLSDLGSTDEEITQGTASHPPAAVSVLNVI
EEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHH
AVGARTAMPKPHFEGDVSNEDLRALTVAALEPTQGQMLWTFGDIGAALACDWLRAAGNKA
HHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHCCCCH
HAISFASMVEQSQRNARKLGVSTLSVKETLSPKTLKDIRYVQGPESASPHAIFMNKGLGI
HHHHHHHHHHHHHHHHHHHCCEEEEHHHHCCCHHHHHHHHHCCCCCCCCCEEEEECCCCE
DLVPETAWMMLRPGGKLIAQASTEDNIAKLHTLQEQHGGIIKHIRIDDTDVHQWRVTKPV
EECCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCC
TPEAVN
CCCCCC
>Mature Secondary Structure 
SAPDSASGSERGHERTHFAVVGDSQDLAQATAPREPAESITLIGIGTDGFEGLGLKARQ
CCCCCCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHH
ALQRASVVIGSWRQLNLVPDAIKAERRPWPGNTKHPDLDALFKEFLGRHVAVLASGDPLF
HHHHHHHHHCCCEEECCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHCCEEEEEECCCCEE
YGVGTAMVHVLGMDRLTVIPGPSSASLACARLGWTVNRTRVVYLGQEPIETLIPIIESGA
EEHHHHHHHHHCCCCEEEECCCCCHHHHHHHHCCEECCEEEEEECCCCHHHHHHHHHCCC
QFLVLGKDEFSTAQVATLLNELGLGETPLTVLSDLGSTDEEITQGTASHPPAAVSVLNVI
EEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHH
AVGARTAMPKPHFEGDVSNEDLRALTVAALEPTQGQMLWTFGDIGAALACDWLRAAGNKA
HHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHCCCCH
HAISFASMVEQSQRNARKLGVSTLSVKETLSPKTLKDIRYVQGPESASPHAIFMNKGLGI
HHHHHHHHHHHHHHHHHHHCCEEEEHHHHCCCHHHHHHHHHCCCCCCCCCEEEEECCCCE
DLVPETAWMMLRPGGKLIAQASTEDNIAKLHTLQEQHGGIIKHIRIDDTDVHQWRVTKPV
EECCCCEEEEECCCCCEEEECCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCC
TPEAVN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]