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The map label for this gene is irtA [H]

Identifier: 145295584

GI number: 145295584

Start: 1673832

End: 1674266

Strand: Direct

Name: irtA [H]

Synonym: cgR_1511

Alternate gene names: 145295584

Gene position: 1673832-1674266 (Clockwise)

Preceding gene: 145295577

Following gene: 145295585

Centisome position: 50.51

GC content: 59.31

Gene sequence:

>435_bases
ATGGGCAAGGGATTTACCGGCGCTATTTTGACCGTCATGGGCGTGAAATCGCATATCGCCACCACCACGGGAAAAACTGT
GATCAATGACCGCATGGTGACCATTCATTTTCATTCCGAGACGCTGCTCAACACGGAAGGTGAAGTCCCCGGCGATTGGC
CGCGTCTGTGGTTCCCGCACGAGAGCCGACCTGGAAAGCTCTACCAACGCGCCTACACCTTGACCAACGTGGATGCCGAT
GCCGGTACCTTTGACCTGGCTTTTGTGCTGCACGAGCCGCTGGGGCCCGCCTCGGCGTGGGCGACGCGCTGCGAGGCCGG
GGAAAGCCTGGAAGTCATGCGCTACCCAGGAATTCCGTTCACCATCCCAGATCCAGCGCCGCGTGGCTTCCTTTTCTTAG
GCGATCTGCTCGATTCTGGAGACCTTGGACGGTGA

Upstream 100 bases:

>100_bases
GCTGAGCTAGTGCTTTTGTGACACACCTCTTGCGAATGTTGATTAGGTTAGGCAAGCCATATTTAGAAAGTGTTGTGAAA
GGATAAGGGAGAAAGGAAAC

Downstream 100 bases:

>100_bases
AATCCCTGCGACCGCGTATCTTATCGCCCACGATCCACTTGATTACACCTTCGATTTTCCCCAGGGCGAGCACATCACCG
CGCAGTGGATTTCCAACGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MGKGFTGAILTVMGVKSHIATTTGKTVINDRMVTIHFHSETLLNTEGEVPGDWPRLWFPHESRPGKLYQRAYTLTNVDAD
AGTFDLAFVLHEPLGPASAWATRCEAGESLEVMRYPGIPFTIPDPAPRGFLFLGDLLDSGDLGR

Sequences:

>Translated_144_residues
MGKGFTGAILTVMGVKSHIATTTGKTVINDRMVTIHFHSETLLNTEGEVPGDWPRLWFPHESRPGKLYQRAYTLTNVDAD
AGTFDLAFVLHEPLGPASAWATRCEAGESLEVMRYPGIPFTIPDPAPRGFLFLGDLLDSGDLGR
>Mature_143_residues
GKGFTGAILTVMGVKSHIATTTGKTVINDRMVTIHFHSETLLNTEGEVPGDWPRLWFPHESRPGKLYQRAYTLTNVDADA
GTFDLAFVLHEPLGPASAWATRCEAGESLEVMRYPGIPFTIPDPAPRGFLFLGDLLDSGDLGR

Specific function: Part of the ABC transporter complex IrtAB involved in iron import. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG2375

COG function: function code P; Siderophore-interacting protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017940
- InterPro:   IPR001140
- InterPro:   IPR011527
- InterPro:   IPR003593
- InterPro:   IPR013113
- InterPro:   IPR017927
- InterPro:   IPR017938
- InterPro:   IPR007037 [H]

Pfam domain/function: PF00664 ABC_membrane; PF00005 ABC_tran; PF08021 FAD_binding_9; PF04954 SIP [H]

EC number: NA

Molecular weight: Translated: 15729; Mature: 15598

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKGFTGAILTVMGVKSHIATTTGKTVINDRMVTIHFHSETLLNTEGEVPGDWPRLWFPH
CCCCCCCHHHHHHHHHHHHCCCCCCEEECCEEEEEEECCCEEECCCCCCCCCCCEEECCC
ESRPGKLYQRAYTLTNVDADAGTFDLAFVLHEPLGPASAWATRCEAGESLEVMRYPGIPF
CCCCCHHHHHEEEEECCCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCE
TIPDPAPRGFLFLGDLLDSGDLGR
ECCCCCCCCEEEEEEECCCCCCCC
>Mature Secondary Structure 
GKGFTGAILTVMGVKSHIATTTGKTVINDRMVTIHFHSETLLNTEGEVPGDWPRLWFPH
CCCCCCHHHHHHHHHHHHCCCCCCEEECCEEEEEEECCCEEECCCCCCCCCCCEEECCC
ESRPGKLYQRAYTLTNVDADAGTFDLAFVLHEPLGPASAWATRCEAGESLEVMRYPGIPF
CCCCCHHHHHEEEEECCCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCE
TIPDPAPRGFLFLGDLLDSGDLGR
ECCCCCCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]