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The map label for this gene is mdmB [H]

Identifier: 145295527

GI number: 145295527

Start: 1608067

End: 1609452

Strand: Direct

Name: mdmB [H]

Synonym: cgR_1455

Alternate gene names: 145295527

Gene position: 1608067-1609452 (Clockwise)

Preceding gene: 145295526

Following gene: 145295528

Centisome position: 48.52

GC content: 51.15

Gene sequence:

>1386_bases
ATGACGTCGAAAAGCATTAGCGGCAAGCGCCCGAATCTGCCGTCGCTCACTGGAGCGCGGTGGCTCGCGGCGCTGGCTGT
TTATTTTTTGCATGCGTTGGTGTTTTTGTCGGTGTATCCGTTCCAGCAGTCGGAACTGTTTGCCACAATCCATAAATTTG
TCCCCATGCAGCTGGGTTCAGCTGGTGTGACCTTCTTCTTCATCCTGTCCGGATTTTTGATCTATTGGTCAAATAGCCAG
CTCAAGGGTTTTAAGAATGTGCTGTATTACTGCAAGCGTCGCATCACCAAGATTTATCCCATGCATCTGATTGCGTTGGC
GATGTTTATTGTGGCGTCCGCGAAGTTCACGACCACAGGCATTACGTGGGTGTTGAATTTTGCGCGAGTGGAGCTGTGGC
TGCCGAACGCACTGCTGATCCACACGTGGAATCCTGATTGGGTGACGCTGGGTGGATTGAATGTGCCATCGTGGTCGCTG
GGCGCGGAAATGCTGTTCTACCTGACATTCCCACTGTTTATTCCGTTGGTGCGCAAAGTGAAGGGCGTGGGCAACTGGTG
GGCATTTGGCATCACCTTTGCCGTGAGCTTGGCGCTGATTACAGTGATTCACTTTTATGCGGACGGACCAAAGGGGATTG
AGAACTTCTTTGTTCCTCGCTTGTGGGACACCAATGTTTCACCGGTCGCGGAAGTACACGCCGATCCAGTGTGGTTCATG
CAGGAAGAAATTCCCGTGCTGGAATCTTACTGGCTGTCTTACTACTTCCCTCTGACCAGACTCATCGAGTTCTACCTCGG
TGTGTTTGGCGCGAAGCTGGTTGCAGAAGGCATGTTTAAAAACACCAACATCACCATCCCACTGATCGCACTAGCTGTTT
CTTTTGTTGCTACTTGGTTTGTGCCACTGGCATTCAAGATGTCTGTCATCATGTCCCTGCCAATGGCTTTTGTGGTGGCA
ACGCTTGCGGTGAGAGACATTGAAGGCAAGAGTGGGGAAATCGCCTCGCCTCGCGCGGTTTTGTTGGGCAATATTTCCTT
TGCCTTCTACATGGTGCAGTTCCCAGTGATGGTGTTTGTGCAGCGCTATTTCATCGCTGGCAAGGAATACGGTTTCCTTG
GCTGGGCATTCTATGCAGTGGTGTGTTTCATCGTGTCAGTCATTCTTGCGTGGGTGCTGTTTACCTTCGTTGATGATCCT
TTGATGAAGGCCACGGCGCGCAAGAAGGGGAGTAGGCGCTTGAAGCAGTCCAATATTTTGGTCCGTGACCTGAAAGTTCT
CTTCGGCAAAAGCCCCGAAAAGCCGTTAAAAGTTGAGACTCGCGCTGAGAATCTCGCAGAAAACTCCGAAGCTCCCGCTA
AGGTAGCTACCGGAATCAAATCTTAG

Upstream 100 bases:

>100_bases
TTGATGCACGTGCAGAAATCGTCGGCGGTCCGTGGCACCCATCTGTTAAGGGAGACTCGGTTACTGCAGGGATCCTGCGA
GATCGAGTAAACGCCTAAAG

Downstream 100 bases:

>100_bases
GGAAGGAAAACATATGGCTATTTACCGTAAGCTTGCGGCTTCCGCTGCAGCACTGGCCCTGTCCGCATCACTGGTCGCTT
GTGGCGACTCTGAGGACACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MTSKSISGKRPNLPSLTGARWLAALAVYFLHALVFLSVYPFQQSELFATIHKFVPMQLGSAGVTFFFILSGFLIYWSNSQ
LKGFKNVLYYCKRRITKIYPMHLIALAMFIVASAKFTTTGITWVLNFARVELWLPNALLIHTWNPDWVTLGGLNVPSWSL
GAEMLFYLTFPLFIPLVRKVKGVGNWWAFGITFAVSLALITVIHFYADGPKGIENFFVPRLWDTNVSPVAEVHADPVWFM
QEEIPVLESYWLSYYFPLTRLIEFYLGVFGAKLVAEGMFKNTNITIPLIALAVSFVATWFVPLAFKMSVIMSLPMAFVVA
TLAVRDIEGKSGEIASPRAVLLGNISFAFYMVQFPVMVFVQRYFIAGKEYGFLGWAFYAVVCFIVSVILAWVLFTFVDDP
LMKATARKKGSRRLKQSNILVRDLKVLFGKSPEKPLKVETRAENLAENSEAPAKVATGIKS

Sequences:

>Translated_461_residues
MTSKSISGKRPNLPSLTGARWLAALAVYFLHALVFLSVYPFQQSELFATIHKFVPMQLGSAGVTFFFILSGFLIYWSNSQ
LKGFKNVLYYCKRRITKIYPMHLIALAMFIVASAKFTTTGITWVLNFARVELWLPNALLIHTWNPDWVTLGGLNVPSWSL
GAEMLFYLTFPLFIPLVRKVKGVGNWWAFGITFAVSLALITVIHFYADGPKGIENFFVPRLWDTNVSPVAEVHADPVWFM
QEEIPVLESYWLSYYFPLTRLIEFYLGVFGAKLVAEGMFKNTNITIPLIALAVSFVATWFVPLAFKMSVIMSLPMAFVVA
TLAVRDIEGKSGEIASPRAVLLGNISFAFYMVQFPVMVFVQRYFIAGKEYGFLGWAFYAVVCFIVSVILAWVLFTFVDDP
LMKATARKKGSRRLKQSNILVRDLKVLFGKSPEKPLKVETRAENLAENSEAPAKVATGIKS
>Mature_460_residues
TSKSISGKRPNLPSLTGARWLAALAVYFLHALVFLSVYPFQQSELFATIHKFVPMQLGSAGVTFFFILSGFLIYWSNSQL
KGFKNVLYYCKRRITKIYPMHLIALAMFIVASAKFTTTGITWVLNFARVELWLPNALLIHTWNPDWVTLGGLNVPSWSLG
AEMLFYLTFPLFIPLVRKVKGVGNWWAFGITFAVSLALITVIHFYADGPKGIENFFVPRLWDTNVSPVAEVHADPVWFMQ
EEIPVLESYWLSYYFPLTRLIEFYLGVFGAKLVAEGMFKNTNITIPLIALAVSFVATWFVPLAFKMSVIMSLPMAFVVAT
LAVRDIEGKSGEIASPRAVLLGNISFAFYMVQFPVMVFVQRYFIAGKEYGFLGWAFYAVVCFIVSVILAWVLFTFVDDPL
MKATARKKGSRRLKQSNILVRDLKVLFGKSPEKPLKVETRAENLAENSEAPAKVATGIKS

Specific function: Catalyzes the acylation of the mycaminose sugar during midecamycin biosynthesis [H]

COG id: COG1835

COG function: function code I; Predicted acyltransferases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyltransferase 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002656 [H]

Pfam domain/function: PF01757 Acyl_transf_3 [H]

EC number: NA

Molecular weight: Translated: 51934; Mature: 51803

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKSISGKRPNLPSLTGARWLAALAVYFLHALVFLSVYPFQQSELFATIHKFVPMQLGS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
AGVTFFFILSGFLIYWSNSQLKGFKNVLYYCKRRITKIYPMHLIALAMFIVASAKFTTTG
CHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ITWVLNFARVELWLPNALLIHTWNPDWVTLGGLNVPSWSLGAEMLFYLTFPLFIPLVRKV
HHHHHHHHHHEEECCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KGVGNWWAFGITFAVSLALITVIHFYADGPKGIENFFVPRLWDTNVSPVAEVHADPVWFM
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHCCCCEEEH
QEEIPVLESYWLSYYFPLTRLIEFYLGVFGAKLVAEGMFKNTNITIPLIALAVSFVATWF
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VPLAFKMSVIMSLPMAFVVATLAVRDIEGKSGEIASPRAVLLGNISFAFYMVQFPVMVFV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHH
QRYFIAGKEYGFLGWAFYAVVCFIVSVILAWVLFTFVDDPLMKATARKKGSRRLKQSNIL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VRDLKVLFGKSPEKPLKVETRAENLAENSEAPAKVATGIKS
HHHHHHHHCCCCCCCCEEHHHHHHHHCCCCCCHHHHCCCCC
>Mature Secondary Structure 
TSKSISGKRPNLPSLTGARWLAALAVYFLHALVFLSVYPFQQSELFATIHKFVPMQLGS
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
AGVTFFFILSGFLIYWSNSQLKGFKNVLYYCKRRITKIYPMHLIALAMFIVASAKFTTTG
CHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ITWVLNFARVELWLPNALLIHTWNPDWVTLGGLNVPSWSLGAEMLFYLTFPLFIPLVRKV
HHHHHHHHHHEEECCCEEEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
KGVGNWWAFGITFAVSLALITVIHFYADGPKGIENFFVPRLWDTNVSPVAEVHADPVWFM
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHCCCCEEEH
QEEIPVLESYWLSYYFPLTRLIEFYLGVFGAKLVAEGMFKNTNITIPLIALAVSFVATWF
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VPLAFKMSVIMSLPMAFVVATLAVRDIEGKSGEIASPRAVLLGNISFAFYMVQFPVMVFV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHH
QRYFIAGKEYGFLGWAFYAVVCFIVSVILAWVLFTFVDDPLMKATARKKGSRRLKQSNIL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VRDLKVLFGKSPEKPLKVETRAENLAENSEAPAKVATGIKS
HHHHHHHHCCCCCCCCEEHHHHHHHHCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1629172 [H]